Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,984 recruiting studies in this area right now.
By phase
- Not applicable7,964
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California465
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,981 total
- NCT04349358Recruiting
PET/CT scan test to find bone lesions in new myeloma
This trial compares two types of PET/CT scans to see which one better finds lesions (areas of disease) in people with newly diagnosed multiple myeloma. If you qualify, you may help doctors choose the most useful scan to guide care.
BesançonAges 18–75 - NCT04353960Recruiting
Study of heart rate response during eye muscle surgery
This study looks at how the heart rate changes when eye doctors move the eye muscles during strabismus (eye alignment) surgery. It may help doctors better understand and manage this normal reflex during surgery.
Anchorage, AlaskaAges 1 month–100 years - NCT04355975Recruiting
Study follow-up outcomes after a lung blood clot
This trial looks at how people do after an acute pulmonary embolism (a blood clot in the lungs). It aims to understand real-world outcomes over follow-up and may help improve how care teams track patients after treatment.
Bern, Canton of BernAges Any age - NCT04361994Recruiting
GErman Italian Spanish Takotsubo Registry
This registry studies people who have been diagnosed with Takotsubo syndrome (a temporary heart condition that can mimic a heart attack). It helps researchers learn about who gets it, what happens over time, and what factors may affect recovery.
Lübeck, Schleswig-HolsteinAges 18 years+ - NCT04367220Recruiting
Canadian heart imaging registry for people getting scans
This trial is a registry that collects information from people referred for hospital heart imaging. It helps researchers better understand cardiovascular imaging and care, without changing your treatment.
Calgary, AlbertaAges 18 years+ - NCT04372563Recruiting
Check treatment for aortic enlargement with tricuspid valve
This trial studies how to treat an enlarged part of the ascending aorta in people who have a tricuspid aortic valve. It may help slow or manage the risk connected to aorta enlargement.
TomskAges 45–75 - NCT04375306Recruiting
Testing a heart-pressure ratio to choose bypass surgery plan
This trial studies whether a special heart “pressure/flow ratio” test (measured during the procedure) can help doctors choose the best plan for coronary bypass surgery. It may improve how bypass targets the problem blood vessels, but only if certain heart and health factors fit the study rules.
BonheidenAges 18 years+ - NCT04375722Recruiting
Brain stimulation study for language problems after stroke
This trial tests whether gentle, noninvasive brain stimulation (tACS) can improve speech and language (aphasia) after stroke. You may be asked to do language and thinking tests before and after the stimulation to see if it helps.
Milwaukee, WisconsinAges 18–85 - NCT04374799RecruitingPhase 3
Heparin vs placebo during cardiac catheterization
This trial tests whether giving heparin (a blood thinner) during a specific type of heart procedure is safer and works better than not giving it. It focuses on patients where the blood supply in the hand’s artery connection is functioning properly.
Hamilton, OntarioAges 18 years+ - NCT04377854Recruiting
Checking whether BNP predicts outcomes in advanced heart failure
This study looks at whether a blood test called BNP can help predict what happens over time in people being evaluated for advanced heart failure treatment. It may help doctors better plan care and follow-up for patients long-term.
Copenhagen, DKAges 18 years+ - NCT04377490Recruiting
Study of blood clots in hospitalized COVID-19 patients
This study looks at how often blood clot–related problems happen in people hospitalized with serious COVID-19 lung illness. It may help doctors understand risks and improve care for patients in the hospital.
AmiensAges 18 years+ - NCT04388943Recruiting
BRICCS study: health data for cardiovascular research
This trial helps researchers study heart (cardiovascular) conditions using information collected about your care. It may help improve how doctors understand and treat cardiovascular diseases over time.
LeicesterAges 18–90 - NCT04393389Recruiting
Follow-up study for a drug-coated balloon in leg arteries
This is a post-market follow-up study of a drug-coated balloon used to open blocked leg arteries. It checks how safe the device is and how well it works over time after your procedure.
Halle, Saxony-AnhaltAges 18 years+ - NCT04395495Recruiting
RASopathy disorder study biobank for kids and families
This study collects and stores health samples and information from people with RASopathy conditions (like Noonan or Costello syndromes) and from family members who may not have the condition. It helps researchers understand these disorders and supports future studies that could lead to better care.
Cincinnati, OhioAges Any age - NCT04396899RecruitingPhase 1/Phase 2
Stem cell heart patch for advanced heart failure
This early-phase study tests a lab-made heart tissue (“engineered myocardium”) placed surgically to help the heart work better in people with advanced heart failure. It mainly checks safety first, and also looks for signs the patch can improve heart function in selected patients.
Göttingen, Lower SaxonyAges 18–80 - NCT04398992Recruiting
Anti-inflammatory add-on treatment after certain aortic conditions
This study tests whether an “add-on” anti-inflammatory approach can help after surgery for certain problems affecting the aorta (the body’s main artery) soon after symptoms begin. It may be designed to reduce inflammation-related complications in people who are treated quickly and can join follow-up.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04399200Recruiting
Study apnea after stroke to prevent new heart events
This trial looks at sleep apnea (breathing pauses during sleep) in people soon after a first stroke or a TIA, to see if it can be linked to new cardiovascular (heart/blood vessel) events. It also aims to make sure you can safely follow the study and rehabilitation plan.
GrenobleAges 18–85 - NCT04402086Recruiting
Rheumatology patient and skin sample registry study at Yale
This study builds a health record and blood/skin sample collection for people with rheumatic autoimmune diseases who are getting care at Yale. It may help researchers understand these conditions and develop better tests or treatments over time.
New Haven, ConnecticutAges 18–99 - NCT04405583Recruiting
Follow-up study for a heart device in heart failure patients
This study follows people with chronic heart failure to see how well an implanted device (called the Occlutech AFR) works and whether it is safe over time. It may help doctors better understand who benefits and how to manage treatment safely.
BesançonAges 18 years+ - NCT04408430Recruiting
Valve replacement for severe mitral valve disease in high-risk adults
This trial tests a less-invasive way to treat severe mitral valve problems using a transcatheter valve. It may help people who are too high-risk for standard open-heart mitral surgery by improving symptoms and heart function.
Gilbert, ArizonaAges 18 years+ - NCT04407780Recruiting
Cardio-oncology patient registry
This is a registry (a research database) for people who are being followed in cardio-oncology, which means care for heart problems related to cancer or cancer treatments. It may help doctors better understand these conditions and improve future care.
ParisAges 18 years+ - NCT04409431Recruiting
Spironolactone plus adrenal nerve treatment for adrenal overactivity
This trial studies whether blocking part of the adrenal blood supply (“adrenal artery ablation”) along with spironolactone can improve hormone-driven high blood pressure caused by primary aldosteronism. It may help people who have confirmed adrenal overactivity and do not want surgery.
Chongqing, Chongqing MunicipalityAges 30–60 - NCT04413331Recruiting
Study follows adults with vasculitis over time
This observational study follows adults with vasculitis (inflammation of blood vessels) during an active flare or relapse. It aims to better understand how the disease changes over time and may help researchers plan future treatments.
ParisAges 18 years+ - NCT04412187Recruiting
Study of inflammation after a new stroke
This study looks at inflammation-related changes soon after an acute ischemic stroke (a type caused by a blocked blood vessel). It may help researchers understand what factors drive recovery and how they could be targeted in the future.
Munich, GermanyAges 50 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,984 recruiting cardiology studies from the U.S. registry right now, out of 15,291 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
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- Pain
- Injuries & trauma
- Mouth & dental
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.