Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT04459806Recruiting
Study dose timing to improve care for brain injury
This trial studies how to time medication or treatment doses when a person has serious brain injury, using measurements from a pressure monitor in the skull. It may help doctors manage brain swelling and pressure more effectively.
Monza, MBAges 18–80 - NCT04460573RecruitingPhase 2
Using a smart boot to improve diabetic foot offloading
This trial studies whether a special “smart boot” can help people with diabetic foot ulcers rest (offload) the affected foot as they should. Better offloading may improve healing by reducing pressure on the wound.
Downey, CaliforniaAges 18 years+ - NCT04463316Recruiting
Clinic study for people with rare genetic conditions
This study is for people who have a rare syndrome or rare congenital condition and are seen at a rare-disease clinic. It aims to better understand these conditions and how care works in a team setting, which may help guide future treatment decisions.
Rotterdam, South HollandAges 18 years+ - NCT04464655Recruiting
10-minute heart MRI protocol for people with heart conditions
This study uses a short, 10-minute heart MRI to check how well it works for people who need a clinically indicated heart scan. It may help streamline heart MRI testing, making exams faster while still providing useful heart information.
Montreal, QuebecAges 18 years+ - NCT04467671RecruitingPhase 2
Tested new blood vessel graft for a heart surgery
This trial studies whether a newer “tissue-engineered” blood vessel graft is safe and works well in children who need a specific heart surgery connection outside the heart. It may help by offering a new type of graft, but your team will screen for size and medical factors first.
Columbus, OhioAges Any age - NCT04465591Recruiting
Study of troponin fragments after heart muscle injury
This study looks at a specific lab pattern (“troponin fragmentation”) in blood samples taken from people after a heart muscle injury. It may help researchers understand the injury better and improve how it’s measured.
Turku, Southwest FinlandAges 18 years+ - NCT04466852Recruiting
Telemedicine program after hospital discharge for heart failure
This trial checks whether follow-up by telemedicine after a hospital stay for heart failure can help patients after discharge. It may help you stay connected to care without frequent in-person visits.
Rio de JaneiroAges 18 years+ - NCT04469517Recruiting
Study of low-oxygen factors in hereditary bleeding disorder
This study looks at how “low-oxygen” signals may affect people with hereditary hemorrhagic telangiectasia (HHT), a genetic bleeding disorder. It may help researchers understand what drives symptoms and could guide future treatments.
Essen, North Rhine-WestphaliaAges 18 years+ - NCT04475510Recruiting
Stop blood-thinner therapy after PFO closure in younger stroke patients
This trial tests whether it’s safe to stop antithrombotic (blood-thinner) treatment after a successful hole-in-the-heart procedure (PFO closure) in people age 60 and under who had an unexplained stroke or TIA. It may help some people avoid long-term blood-thinner side effects if their risk stays low.
Québec, QuebecAges 18–60 - NCT04477330Recruiting
Brain stimulation to improve walking after a stroke
This study tests whether a brain stimulation method (“cortical priming”) can improve walking after a stroke. It may help people with ongoing walking problems improve gait and leg control over a rehabilitation program.
Chicago, IllinoisAges 18 years+ - NCT04479072RecruitingPhase 4
Aspirin for preeclampsia during delivery
This trial tests whether taking aspirin during pregnancy around the time of delivery helps people with preeclampsia. You may be asked to take aspirin as part of a study plan, with monitoring to see how you do.
Chicago, IllinoisAges 18–45 - NCT04483206RecruitingPhase 1
Personalized stem cell transplant for multiple myeloma
This Phase 1 study tests a personalized (tailored) autologous stem cell transplant for people with multiple myeloma or related plasma cell diseases. The goal is to see how safe it is and how well it works, using your own stem cells.
Atlanta, GeorgiaAges 18 years+ - NCT04487340Recruiting
Online database for people with acute stroke care
This study sets up an online database to track people who have had a stroke soon after it happens. The goal is to understand and improve how stroke care quality is evaluated.
Hangzhou, ZhejiangAges Any age - NCT04489199Recruiting
Join the Dijon stroke patient registry study
This study follows people who are already in the Dijon Stroke Registry and asks if they agree to participate. If you say yes, your information may be used to better understand stroke outcomes and care.
DijonAges 18 years+ - NCT04490161Recruiting
Preventing blood-vessel spasm after aneurysm brain bleeding
This trial studies a spinal fluid (CSF) treatment to help prevent dangerous blood-vessel tightening (vasospasm) after a type of brain bleed caused by an aneurysm. If you qualify, the goal is to reduce complications soon after aneurysm repair.
Innsbruck, TyrolAges 18–90 - NCT04490720Recruiting
Buckwheat husk extract for heart risk factors
This trial studies whether buckwheat husk extract can improve certain heart-related measurements in people with mildly high blood pressure. It may help lower cardiovascular risk factors by affecting things like blood pressure.
TaipeiAges 20–65 - NCT04493372Recruiting
Testing how well nerves control the heart after spinal cord injury
This study looks at how well the body’s automatic nerve functions (like heart and blood pressure control) work after a traumatic spinal cord injury. The goal is to better understand preserved nerve function and autonomic (automatic body) control, which could help guide future treatments.
Rochester, MinnesotaAges 18–50 - NCT04493970Recruiting
Study tests a CPR training app for high school students
This trial looks at whether using a required CPR training approach (through instruction and an app) improves learning among high school students. You may be asked to complete a short survey to help researchers understand how well the training is working.
Overland Park, KansasAges 12–25 - NCT04496947Recruiting
Stress reduction program for stressed adults’ heart health
This pilot study tests whether a stress-reduction program can improve heart-related outcomes for adults who feel highly stressed. You may be invited because the study focuses on how stress affects the body—especially the heart.
Boston, MassachusettsAges 30–65 - NCT04499326Recruiting
Improve quality-of-life reporting after defibrillator heart ablation
This study looks at how to better track patients’ quality of life (how you feel and function) after catheter ablation for a dangerous heart rhythm, using questionnaires you complete. It may help the care team understand how to measure patient outcomes more accurately after treatment.
LondonAges 18 years+ - NCT04499859RecruitingPhase 4
Low-dose cholesterol medicines versus high-dose after heart attack
This study compares two cholesterol treatment approaches after a heart attack: a lower dose combination versus a higher dose single medicine. It aims to see which option works well and is tolerable for people after a treated heart attack.
Bucheon-si, GyeonggidoAges 19 years+ - NCT04500899RecruitingPhase 1/Phase 2
Phenylephrine test to better grade mitral valve leak severity
This trial tests whether a medication called phenylephrine helps doctors measure how severe mitral regurgitation (mitral valve leak) is. If you’re already scheduled for a special ultrasound from the esophagus, this study may help improve how your valve leak is assessed.
New York, New YorkAges 18 years+ - NCT04503395Recruiting
Testing two new ways to repair an abdominal aneurysm
This trial compares two procedures (ESAR and FEVAR) to repair an abdominal aortic aneurysm in people whose anatomy makes the usual repair hard. It may help find a safer, more durable option for patients with challenging aortic neck features.
La Jolla, CaliforniaAges 18 years+ - NCT04505618Recruiting
Eye scan study using special imaging for blood-vessel disease
This study uses a detailed eye scan (optical coherence tomography angiography) to look at how blood vessels in the retina are affected. It may help researchers better understand retinal vascular diseases, though some people will be excluded for safety or image-quality reasons.
Baltimore, MarylandAges 18–99
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,297 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
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- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.