Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,626 recruiting studies in this area right now.
By phase
- Not applicable7,647
- Phase 4471
- Phase 2470
- Phase 3439
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke798
- Heart Failure538
- Hypertension390
- Cardiovascular Diseases374
- Coronary Artery Disease361
- Multiple Myeloma328
- Atrial Fibrillation258
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke138
- Pulmonary Hypertension105
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Acute Coronary Syndrome74
- Obesity74
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine57
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona183
- Massachusetts174
- New York165
- Florida141
- Texas122
- Maryland119
- Minnesota118
- Illinois111
Recruiting studies9,626 total
- NCT07284550Recruiting
Smartphone screening for aortic valve stenosis
This study tests if a smartphone app can detect aortic valve stenosis (a heart valve condition) by recording heart sounds. If successful, it could offer a simple, non-invasive way to screen for this condition without a doctor's visit.
InnsbruckAges 18 years+ - NCT07282041RecruitingPhase 2/Phase 3
A study on dulaglutide for brain artery narrowing after stroke
This trial tests if a once-weekly injection called dulaglutide (Trulicity) helps people with severe narrowing of a major brain artery after a minor stroke or TIA. The goal is to improve blood flow and reduce the risk of another stroke.
SingaporeAges 21–80 - NCT07282301Recruiting
Filter to catch debris during leg artery cleaning
This trial tests a special filter that catches debris during a procedure to clear blockages in the leg artery (the one behind the knee). It aims to reduce the risk of debris traveling to smaller blood vessels, which can cause complications. If you have a hardened leg artery and plan to have plaque removal before a stent or balloon, this study may be for you.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07279259RecruitingPhase 2
Blood pressure management after stroke clot-dissolving treatment
This trial tests how managing high blood pressure during clot-dissolving treatment for acute ischemic stroke affects recovery. It is for patients who have high blood pressure at the start of treatment.
ShanghaiAges 18–80 - NCT07283159RecruitingPhase 2
Tenecteplase plus a second drug for stroke recovery
This study tests whether giving a second drug (urinary kallidinogenase) after the clot-busting drug tenecteplase can help people with moderate to severe ischemic strokes recover better. It is for patients who started treatment within 4.5 hours of symptoms.
ShenyangAges 18 years+ - NCT07284446Recruiting
Depression, memory, and outcomes in heart failure patients
This study looks at how depression and memory problems affect recovery in people hospitalized with worsening chronic heart failure. It aims to find better ways to support patients during their hospital stay.
KaunasAges 18–85 - NCT07282717Recruiting
Skin cell study for COL5A mutation and aortic aneurysm
This trial collects a small skin sample from adults with a COL5A gene mutation and thoracic aortic aneurysm. Researchers study the skin cells to better understand the condition and explore potential treatments.
San Donato Milanese, ItalyAges 18 years+ - NCT07284641RecruitingPhase 2
Stem cell transplant for immune disorders
This trial tests a stem cell transplant to treat common variable immunodeficiency (CVID) and other immune problems. It aims to replace a faulty immune system with a healthy one from a donor.
Pittsburgh, PennsylvaniaAges 5–40 - NCT06882967Recruiting
Aortic aneurysm stent trial for high-risk anatomy
This trial tests a new stenting approach for patients with large or fast-growing aneurysms in the lower part of the chest's main artery. It focuses on people whose aneurysm shape makes standard treatment tricky.
Roma, RMAges 18 years+ - NCT06884631Recruiting
Heart failure risk assessment with exercise test and kidney health
This study uses a special exercise test, along with heart and kidney measurements, to better predict risks for people with heart failure. It may help your doctors understand your condition and choose the best care for you.
Milan, ItalyAges 18 years+ - NCT03710902Recruiting
Mobile coaching to lower heart risk after stroke
This trial tests whether a mobile technology program can help people manage risk factors like high blood pressure after an ischemic stroke or a “mini-stroke” (TIA). It may help lower future cardiovascular risks by improving day-to-day control of these conditions.
HämeenlinnaAges 40 years+ - NCT04513639RecruitingPhase 2/Phase 3
Checking treatment for multiple myeloma after MRD becomes negative
This study looks at whether people with newly diagnosed multiple myeloma can safely continue or adjust treatment after they reach “MRD-negative,” meaning very low signs of disease in the bone marrow. It may help reduce the chance of relapse while avoiding unnecessary treatment for some patients.
ÅlesundAges 18–75 - NCT05496751Recruiting
Exercise study for people with low activity habits
This study looks at how much your body’s response to exercise can vary over time. They’re enrolling people who are usually sedentary and whose weight and BMI fit their targets, to better understand exercise effects.
Kingston, OntarioAges 25–65 - NCT05312164Recruiting
Study collects heart procedure measurements for coronary artery disease
This study helps collect measurement data during a heart catheter procedure when coronary disease is suspected. You may be eligible if you’re having a catheter-based evaluation and doctors plan to assess blood flow to determine how severe a new heart blockage is.
Palo Alto, CaliforniaAges 18 years+ - NCT06262529Recruiting
Thinking after a Stroke: A Study of Memory and Thinking
This study looks at thinking and memory problems in younger adults (18 to 45) who have had an ischemic stroke. It aims to understand how a stroke affects the brain's ability to think clearly.
CannesAges 18–45 - NCT06885307Recruiting
Building a research network for children with heart conditions
This study is building a network of hospitals across China to help children with congenital heart disease. If your child was born with a heart problem and is under 18, they may be able to join and help improve care for kids like them.
Wuhan, HubeiAges Up to 18 years - NCT06862427Recruiting
Healthy lifestyle app for firefighters
This study tests a smartphone app that helps firefighters adopt healthier habits like better eating, exercise, and stress management. It aims to see if using the app can improve your overall health and well-being.
TaipeiAges 20 years+ - NCT06758375RecruitingPhase 2
Low dose teclistamab for newly diagnosed multiple myeloma
This trial tests a lower dose of the drug teclistamab in people newly diagnosed with multiple myeloma. It aims to see if a lower dose is still effective and has fewer side effects.
Monterrey, Nuevo LeónAges 18 years+ - NCT06887114Recruiting
Lumbar back therapy for better walking and balance after stroke
This study tests a gentle, hands-on therapy called Mulligan Mobilization for the lower back. It may help improve walking, balance, and body awareness after a stroke.
AnkaraAges 30–65 - NCT06887101Recruiting
Stress and heart risks in peripheral artery disease
This study looks at how stress affects heart and blood vessel events in people with peripheral artery disease (PAD). It aims to help understand if stress plays a role in worsening PAD or causing related problems like heart attacks or strokes.
EssenAges 18 years+ - NCT06887894Recruiting
Studying unstable plaque in the carotid artery
This trial looks at specific markers in the blood to better understand unstable plaque in the carotid artery. It may help doctors identify which patients are at higher risk for stroke.
Roma, RMAges 18 years+ - NCT06884098RecruitingPhase 1
A study comparing two versions of a medicine in healthy adults
This trial tests a new version of a medicine (AD-228B) against the original (AD-2284) to see how they work in the body and if they are safe. Healthy volunteers are needed.
SeoulAges 19 years+ - NCT03711110Recruiting
Heart-protection plan for older people with certain cancers
This trial looks at strategies to help prevent heart and blood-vessel problems in people over 65 who have certain cancers. It may help by monitoring and treating heart risks early to lower the chance of future cardiovascular events.
Santiago de Compostela, A CoruñaAges 65 years+ - NCT05386173Recruiting
Tests fetal aortic valve balloon surgery for severe narrowing
This trial studies whether doing a procedure before birth to open a baby’s aortic valve improves outcomes. It compares this approach in a specific group of pregnancies with severe heart flow problems seen on ultrasound.
San Francisco, CaliforniaAges 5 months–7 months
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,626 recruiting cardiology studies from the U.S. registry right now, out of 14,734 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.