Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT05667805RecruitingPhase 4
Testing blood clotting in people with liver cirrhosis
This Phase 4 study looks at how clotting measurements relate to bleeding risk in people with liver cirrhosis who need a planned liver procedure. The study may help doctors understand what coagulation results mean when doing these procedures safely.
ViennaAges 18 years+ - NCT05671406Recruiting
Digital game to help people manage high blood pressure
This study tests whether a sensor-controlled phone/tablet digital game can help people with high blood pressure better take care of their health at home. It may be helpful if you live in a Native American community and are willing to use the technology.
Chapel Hill, North CarolinaAges 18 years+ - NCT05672706Recruiting
Pressure wave test for people with angina
This study looks at how a pressure waveform in the heart’s blood vessels can be analyzed to learn more about angina (chest discomfort from reduced blood flow). You may be asked to undergo specific heart/blood-flow measurements, which could help improve understanding and future care.
HsinchuAges 21 years+ - NCT05674604Recruiting
Cryoneurolysis to reduce knee and shoulder pain in hospital
This trial tests whether a procedure called cryoneurolysis can reduce pain in people recovering from certain recent brain or nerve injuries (like stroke or traumatic brain injury). It may be helpful if you have either hemiplegic shoulder pain or knee pain from osteoarthritis while you’re in inpatient rehab.
Victoria, British ColumbiaAges 18–80 - NCT05676970Recruiting
Telehealth coaching to improve preventive health decisions
This study tests a telehealth program that helps people make better choices about preventive health (like staying on track with healthy care). You may benefit if you can use a phone or computer for visits and want practical guidance delivered remotely.
New Orleans, LouisianaAges 18–55 - NCT05676476Recruiting
Tested extra blood-pressure control to extend pregnancy in preeclampsia
This trial studies whether using specific blood-pressure medicines can help people with non-severe preeclampsia stay pregnant longer. It aims to improve outcomes by treating blood pressure early while monitoring you and the baby closely.
Birmingham, AlabamaAges 14–49 - NCT05677880Recruiting
Study for CADASIL using MRI, blood tests, and follow-up visits
This trial studies CADASIL (a genetic blood-vessel condition in the brain) by following people over time with MRI scans, blood draws, and questionnaires. It may help researchers better understand how the condition changes and how factors like medications affect outcomes.
Los Angeles, CaliforniaAges 18 years+ - NCT05677607Recruiting
Study of brain artery narrowing and small-vessel disease
This study looks at how two types of blood vessel problems in the brain affect each other over time. It may help researchers better understand what to watch for and potentially how to improve outcomes.
Beijing, Beijing MunicipalityAges 30 years+ - NCT05679024RecruitingPhase 3
Apixaban to prevent stroke in atrial fibrillation and kidney failure
This trial tests apixaban (a blood thinner) to prevent stroke in people with atrial fibrillation or atrial flutter who have very poor kidney function or are on dialysis. If you qualify, you may help researchers find a safer way to lower stroke risk for this higher-risk group.
HelsinkiAges 18 years+ - NCT05679206Recruiting
Postpartum care study for pregnancy blood-pressure complications
This study looks at people with preeclampsia during pregnancy and how their lung blood pressure and related symptoms change after delivery. It may help doctors better monitor and manage postpartum risks, especially involving the heart and lungs.
BernAges 16 years+ - NCT05679739Recruiting
Caring for brain after cardiac arrest
This study tests a treatment approach aimed at protecting the brain and supporting better blood flow to the brain after a cardiac arrest. It may help some people who are in a coma right after the event recover more safely or with less brain injury.
SingaporeAges 21–79 - NCT05681702RecruitingPhase 4
Personalizing medicines to reduce bleeding after stent procedure
This trial studies ways to reduce bleeding in people after a stent procedure (PCI) who have been taking two anti-platelet medicines (aspirin plus prasugrel or ticagrelor) for a set amount of time. It may help find a safer plan for preventing blood clots while lowering bleeding risk.
Jacksonville, FloridaAges 18 years+ - NCT05681858Recruiting
Testing heart inflammation and reduced blood flow in MINOCA
This study looks at why some people have chest pain and heart injury signs, but their heart arteries are not blocked. It tests scans of blood flow and heart tissue to better understand the cause and guide care.
BergenAges 18 years+ - NCT05682118Recruiting
Using a new heart scan guide to plan blood-flow procedures
This trial tests whether a computer guidance system can help doctors choose the right pressure/blood-flow measurements during certain heart artery procedures. It may help ensure treatment decisions are based on the clearest information about narrowed arteries.
Yongin, Gyeonggi-doAges 19 years+ - NCT05681988Recruiting
Minimally invasive endoscopic surgery for brain bleeding
This trial studies whether a minimally invasive, image-guided endoscopic procedure can remove blood after a specific type of brain bleed. It may help reduce symptoms and improve outcomes compared with standard care, but you must meet timing and medical criteria.
BaselAges 18–85 - NCT05683093Recruiting
Follow-up study for adults after hypertensive pregnancy
This study follows young adults who previously joined the ALSPAC study to better understand long-term heart and metabolic health after a pregnancy affected by high blood pressure. You may be asked to return for visits and possibly an MRI, and your data may help researchers plan better long-term care.
Oxford, OxfordshireAges 30–40 - NCT05683808RecruitingPhase 2
Apixaban to prevent blood clots in outpatient brain tumor patients
This trial tests whether apixaban, a blood thinner, can prevent dangerous blood clots in people with a certain type of malignant brain tumor who are getting radiation and chemotherapy. It may help lower the risk of clots like leg clots or lung clots.
Burlington, VermontAges 18 years+ - NCT05683873Recruiting
Study of heart stress after stroke using a blood marker
This study looks at how heart function changes soon after a new stroke, and whether a blood marker called GDF-15 can help explain or predict that change. It may help doctors better monitor heart stress after stroke and tailor care sooner.
DijonAges 18 years+ - NCT05684770Recruiting
Remote follow-up for low-risk blood clot patients
This study tests whether remote care (check-ins by phone/video or other remote support) can safely help people with a low-risk deep vein thrombosis or pulmonary embolism after an ER diagnosis. It may improve follow-up and support while reducing the need for frequent in-person visits.
ÉvreuxAges 18 years+ - NCT05685069Recruiting
Studying stroke risk factors in people with silent brain infarcts
This study looks for what may have caused “silent” mini-strokes in the brain that were found on MRI, and which risk factors might be changeable. It may help doctors better understand how to prevent future stroke in people who have no clear stroke symptoms from the finding.
ToursAges 16 years+ - NCT05686447Recruiting
Testing blood samples to study multiple myeloma
This study looks at stored blood (serum) samples to see whether a lab test called MALDI-TOF mass spectrometry can help analyze multiple myeloma proteins. If you have multiple myeloma (or are a healthy matched control), your existing lab samples may be used for testing.
Guangzhou, GuangdongAges Any age - NCT05686642RecruitingPhase 2
Drug LT3001 for sudden stroke symptoms within 24 hours
This Phase 2 study tests LT3001 to improve recovery after an acute ischemic stroke (a stroke caused by blocked blood flow). It is designed for people who can be treated within 24 hours of symptom onset and who meet specific safety and health requirements.
Beijing, Beijing MunicipalityAges 18–80 - NCT05687292Recruiting
Decision tool to shorten breathing machine time in children
This study tests whether a computer “decision support” tool can help doctors safely reduce how long a child stays on a breathing machine after heart surgery. It may help children get off mechanical ventilation sooner and recover faster.
Boston, MassachusettsAges 1 day–12 years - NCT05689385Recruiting
Online cardiac rehab after a heart attack you can do at home
This trial tests an eHealth (phone or internet-based) cardiac rehabilitation program for people after a heart attack, meant to help you recover with safer activity guidance. It may fit you if you’re not able to go to a rehab clinic in person.
TaipeiAges 20 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.