Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT06089577RecruitingPhase 4
Cangrelor for heart blood flow during planned stent procedure
This trial tests if cangrelor, a fast-acting blood thinner, can prevent small vessel damage during a planned stent placement in patients with stable chest pain. It may help improve blood flow to the heart muscle.
FerraraAges 18 years+ - NCT06089902Recruiting
European registry for anomalous aortic origin of coronary arteries
This is a European registry for people with an anomalous origin of a coronary artery from the aorta (AAOCA). It will track how the condition is treated—whether with surgery or monitoring—to learn what works best.
Padova, PDAges Any age - NCT06090201Recruiting
Brain health study for severe bleeding disorders
This study uses brain scans and thinking tests to understand how severe hemophilia or von Willebrand disease affects the brain and memory over time.
LilleAges 18 years+ - NCT06090591Recruiting
Heart condition research registry at Dubrava Hospital
This study is a registry that will collect information from people with certain heart conditions (like having a pacemaker, a blood clot, a heart attack, or a valve replacement procedure called TAVI). The goal is to learn more about these conditions and how they are treated.
ZagrebAges 18 years+ - NCT06091332RecruitingPhase 2
Sirolimus for brainstem cavernoma bleeding
This trial tests if sirolimus, a medicine that may help reduce abnormal blood vessels, can prevent another brain bleed in people who recently had a bleed from a brainstem cavernoma. You would receive either sirolimus or a placebo to see if it works.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06091319Recruiting
Florbetaben imaging for vascular amyloid after heart or brain event
This trial tests whether florbetaben, a special dye, can show amyloid buildup in blood vessels after a recent heart attack, chest pain episode, or stroke. It aims to help doctors better understand and prevent future events.
Ottawa, OntarioAges 18 years+ - NCT06091475Recruiting
Maintaining remission in improved dilated cardiomyopathy
This study tests whether people with dilated cardiomyopathy whose heart function has already recovered to normal can safely stop or reduce one of their heart medications while staying in remission. It aims to find the best way to keep the heart healthy without extra medicines.
LondonAges 18–85 - NCT06091774Recruiting
Digital therapy for heart disease risk factors
This study tests a smartphone app (iATROS) for managing heart disease risk factors in patients with coronary heart disease. If you have had a heart attack, a stent, angioplasty, or bypass surgery, and you can use a smartphone, this program may help you reduce your risk through digital monitoring and guidance.
Munich, BavariaAges 18 years+ - NCT06092034RecruitingPhase 2
Gene therapy for Danon disease in males
This trial tests a gene therapy called RP-A501 for men with Danon disease, a heart condition. It aims to replace the faulty gene that causes the disease to improve heart function.
La Jolla, CaliforniaAges 8 years+ - NCT06092554Recruiting
Probiotics to prevent pneumonia in ventilated patients
This trial tests whether giving probiotics to patients on a breathing machine (mechanical ventilation) can help prevent pneumonia. It is for adults who are on a ventilator after a recent head injury, stroke, or brain bleed.
BrusselsAges 18–80 - NCT06092346Recruiting
Understanding rare purine and pyrimidine metabolism disorders
This study aims to learn more about rare disorders of purine and pyrimidine metabolism (DPPM), which can affect the brain, immune system, kidneys, and muscles. Researchers will study people with these disorders, their family members, and healthy volunteers to better understand the condition over time.
Bethesda, MarylandAges 1 month–100 years - NCT06092437Recruiting
Testing a personalized diuretic plan for acute heart failure
This trial is testing whether a diuretic (water pill) dose tailored to each patient works better for treating fluid buildup during a heart failure flare-up. It may help you get the right amount of medication faster and avoid complications.
Heerlen, LimburgAges 18 years+ - NCT06092736RecruitingPhase 4
Danshen pill for chest pain with normal arteries
This trial tests if a traditional Chinese medicine pill (compound Danshen dripping pill) can help people who have chest pain on exertion but whose heart arteries appear normal or nearly normal on scans. If you have this type of chest pain and fit the criteria, you may be able to join.
Jinan, ShandongAges 30–75 - NCT06092814Recruiting
Brain stimulation to boost language after stroke
This study tests whether a gentle electrical current (tACS) applied to the scalp can improve language abilities in people with aphasia after a stroke. Healthy volunteers are also needed as a comparison group.
Philadelphia, PennsylvaniaAges 18–85 - NCT06093100Recruiting
Wearable device study for Duchenne muscular dystrophy
This study uses a wearable device to track blood sugar levels and heart rate in people with Duchenne muscular dystrophy. It aims to understand how these factors relate to heart health over time.
Nashville, TennesseeAges 10 years+ - NCT06093932RecruitingPhase 4
Songling Xuemaikang Capsules for mild high blood pressure
This study tests whether Songling Xuemaikang Capsules can help lower blood pressure in people with mild hypertension who are not currently on regular medication. It may offer a natural treatment option for managing early-stage high blood pressure.
Beijing, Beijing MunicipalityAges 35–65 - NCT06094205Recruiting
BrainGate2 speech study for people with tetraplegia
This study tests a brain-computer interface to help people with severe paralysis communicate by decoding attempted speech or movements. It may offer a new way to interact with devices using only brain signals.
Sacramento, CaliforniaAges 18–80 - NCT06094478Recruiting
Stroke emergency protocol study
This study tests a hospital stroke protocol to quickly evaluate and manage patients with a stroke caused by a clot (AIS), bleeding in the brain (ICH), or bleeding around the brain (SAH). It may help improve emergency care and outcomes.
New Haven, ConnecticutAges 18 years+ - NCT06095050Recruiting
Embolization for chronic shoulder pain
This trial tests a procedure called embolization to treat long-lasting shoulder pain that hasn't improved with other treatments like physical therapy or injections. The goal is to see if blocking certain blood vessels can reduce pain and improve function.
Boston, MassachusettsAges 21–80 - NCT06095466Recruiting
Heart check with ultrasound in severe liver disease
This study tests if a simple bedside heart ultrasound (echocardiogram) and blood tests can spot early heart problems in people with severe liver disease (cirrhosis) who are in the intensive care unit. It may help doctors better understand and manage heart complications in cirrhosis.
Sector-12, ChandigarhAges 18–65 - NCT06095765RecruitingPhase 3
Colchicine for heart disease after stent placement
This trial tests if colchicine, a common anti-inflammatory medicine, can help prevent future heart problems in people who have coronary artery disease and recently had a stent placed. It's for adults with at least one extra risk factor like diabetes, smoking, or high blood pressure.
AalstAges 45 years+ - NCT06096246Recruiting
Comparing treatments for persistent atrial fibrillation
This study compares two treatments for persistent atrial fibrillation (AF) that lasts more than 7 days but less than 2 years: electrical cardioversion (a shock to reset your heart rhythm) versus catheter ablation (using radio waves to fix the heart's electrical pathways). It aims to find which option works better for patients like you.
LondonAges 18–85 - NCT06096350Recruiting
Nutrition and recovery in recent stroke patients
This study looks at how nutrition affects recovery in people who had a stroke within the last 6 months. It aims to help improve rehabilitation by checking your nutritional status.
Roma, RMAges 18–90 - NCT06098235Recruiting
Test of the Oriental diet for brain health in people at high stroke risk
This trial tests whether a special diet (the Oriental diet) can help protect thinking and memory in people who have several stroke risk factors. It may be a good fit if you are 40 or older and have three or more stroke risk factors, such as high blood pressure, diabetes, or being overweight.
Hangzhou, ZhejiangAges 40 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Pain
- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.