Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,609 recruiting studies in this area right now.
By phase
- Not applicable7,632
- Phase 4472
- Phase 2469
- Phase 3439
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke797
- Heart Failure534
- Hypertension388
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction97
- Congenital Heart Disease84
- Peripheral Arterial Disease79
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California453
- Alabama196
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois112
Recruiting studies9,609 total
- NCT04345627Recruiting
Japanese registry for patients having lead removal from veins
This study collects information about people in Japan who need a procedure to remove heart device wires (leads) through a vein. It helps doctors understand outcomes and improve care for future patients.
Suita, OsakaAges Any age - NCT03729232Recruiting
Japanese registry for people who had catheter ablation
This is a national registry that collects health information from people in Japan who received catheter ablation. It may help doctors and researchers understand outcomes and improve future care.
Suita, OsakaAges Any age - NCT06116942Recruiting
Brain stimulation and computer training for arm recovery after stroke
This trial combines magnetic brain stimulation with computer-based motor training to help improve arm and hand function in people who had a stroke at least 6 months ago. It may be a good fit if you have moderate to severe weakness on one side and can take part in brain-computer interface training.
Leipzig, SaxonyAges 20–80 - NCT06126367Recruiting
Study on lipoprotein(a) and clot breakdown in heart disease
This trial looks at how a type of fat in the blood called lipoprotein(a) and your body's ability to break down clots affect heart disease or heart valve disease. It is for people who are already taking certain cholesterol-lowering medicines or have severe aortic valve narrowing from calcium buildup.
StevenageAges 18 years+ - NCT06125236Recruiting
Stroke study for large artery blockages in Southwest China
This study is collecting information from people in Southwest China who have had a stroke caused by a blocked large or medium artery. The goal is to learn more about these strokes and how to treat them better.
LuzhouAges Any age - NCT06129799Recruiting
Exercise heart MRI for low-flow aortic stenosis
This trial uses a special heart MRI scan before and after exercise to study blood flow in people with a type of aortic stenosis where the heart's pumping function may be reduced. It could help doctors better understand how to treat this condition.
GöttingenAges 18 years+ - NCT06128317Recruiting
Heart attack and chest pain registry study
This study is a registry that collects information from people who come to the hospital with heart-related symptoms like chest pain or high troponin levels. It helps doctors better understand different heart conditions and improve care.
Heidelberg, Baden-WurttembergAges 18 years+ - NCT06129656Recruiting
Cardiac Amyloidosis Registry at Leipzig Hospital
This study is a registry that collects information from people with cardiac amyloidosis. It helps doctors learn more about the condition and how to better treat it.
Leipzig, SaxonyAges Any age - NCT02438085Recruiting
Registry study of acute chest pain heart events in Ferrara
This study records information about heart problems that require hospital care, such as acute coronary syndromes. It helps researchers understand how these events happen in the Ferrara area and what care people receive.
Cona, FerraraAges 18 years+ - NCT05469165RecruitingPhase 2
Testing serotonin blockers after a first heart attack
This Phase 2 trial tests whether blocking serotonin receptors can help after a first heart attack that has caused a specific type of leaking mitral valve problem. It aims to see if the treatment improves heart function and heart-valve measurements while keeping patients safe.
QuébecAges 18–80 - NCT05698901Recruiting
Testing heart blood tests and scans to monitor Fabry disease
This study checks whether certain heart-related blood tests and heart scans can help monitor people with Fabry disease. It may be useful for both people who have never received enzyme replacement therapy and those who have.
TaipeiAges 18 years+ - NCT05275088Recruiting
Transcatheter valve replacement for badly calcified heart valves
This trial tests Prizvalve, a catheter-based procedure to replace a severely damaged “atrioventricular” valve in people at high risk from open-heart surgery. It may help reduce symptoms caused by valve narrowing or leaking when traditional surgery is not a good option.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT05363748Recruiting
Kidney artery fibromuscular dysplasia registry for patients
This registry collects information from people diagnosed with kidney artery fibromuscular dysplasia (or certain similar, “atypical” cases). It helps doctors better understand patterns of the condition and may guide future research and care.
Shanghai, Shanghai MunicipalityAges Any age - NCT05864456Recruiting
Study testing a new valve delivered through a blood vessel
This trial studies Prizvalve Pro™, a new transcatheter (catheter-based) aortic valve replacement, for people with severe aortic valve narrowing who are too high-risk for standard surgery. It may help your heart work better and improve symptoms by replacing the failing valve without open-heart surgery.
ShanghaiAges 65 years+ - NCT06131112Recruiting
PET scan for heart inflammation in sarcoidosis
This study tests if a special PET scan with 64Cu-DOTATATE can detect inflammation in the heart caused by sarcoidosis. It may help diagnose heart sarcoidosis more accurately in people with symptoms or known disease.
CopenhagenAges 18 years+ - NCT06136429Recruiting
A study of a new valve device for severe aortic stenosis
This trial tests a new valve device placed through a small tube (catheter) to treat severe aortic stenosis, a condition where the aortic valve is narrowed and doesn't open fully. It's for patients who cannot have traditional open-heart surgery.
BeijingAges 70 years+ - NCT06138457Recruiting
How a hands-on exam affects stress in medical students
This study looks at how a type of hands-on exam (the OSCE) affects stress levels in medical students. If you're a medical student willing to join, you can help researchers understand exam stress better.
Clermont-Ferrand, Auvergne-Rhône-AlpesAges 18 years+ - NCT05310461Recruiting
Early or delayed valve surgery for mixed heart valve disease
This study compares doing aortic valve replacement sooner versus waiting, in people with moderate aortic valve narrowing plus at least moderate leakage in the mitral valve. It aims to see which timing improves heart symptoms and outcomes while keeping treatment safe.
BernAges 18 years+ - NCT06039735Recruiting
Heart ultrasound study in multiple myeloma treated with RVd
This study looks at how a new heart ultrasound test can measure heart side effects and overall outcomes in people with multiple myeloma who are treated with the RVd drug combination. It may help doctors better understand heart risks during treatment.
Jinan, ShandongAges 18–70 - NCT06082466Recruiting
Comparing two types of leg bypass surgery
This study compares two types of bypass surgery for blocked leg arteries. One uses a standard vein from your own body, and the other uses a vein supported by a special metal frame. The goal is to see which works better and lasts longer.
SalzburgAges 18 years+ - NCT06142474RecruitingPhase 3
SGLT2 inhibitors for heart failure patients during ventilator weaning
This trial tests a heart failure medication (SGLT2 inhibitor) to help people with heart failure who are on a breathing machine (ventilator) get better and come off the machine faster. It is for patients with a specific type of heart failure where the heart pumps weakly (EF ≤ 40%).
TaipeiAges 20 years+ - NCT01670383Recruiting
Study sample collection for sepsis and after cardiac arrest
This trial collects and stores small samples from people in the ICU who are either being treated for sepsis or who have survived a non-traumatic cardiac arrest. It may help researchers better understand how the body changes after severe infection or after revival, which could improve future care.
SeoulAges 16 years+ - NCT04347434RecruitingPhase 4
Long-term cholesterol medicines after heart attack
This trial studies how well long-term cholesterol-lowering treatment works in people who recently had a heart attack (STEMI or NSTEMI). It may help your care team understand which patients benefit most and how treatment should be continued safely.
PenzaAges 30–70 - NCT05292209RecruitingPhase 2
RiLuzole pill to reduce atrial fibrillation on heart monitoring
This Phase 2 study tests whether riLuzole can reduce episodes of atrial fibrillation (an irregular heart rhythm) around the time of planned cardioversion. Doctors will monitor your heart using a Holter monitor to count and compare rhythm episodes.
Salt Lake City, UtahAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,609 recruiting cardiology studies from the U.S. registry right now, out of 14,617 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.