Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,001 recruiting studies in this area right now.
By phase
- Not applicable7,980
- Phase 2482
- Phase 4481
- Phase 3447
- Phase 1360
- Phase 1/Phase 2163
- Phase 2/Phase 388
Top conditions
- Stroke846
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation268
- Ischemic Stroke200
- Atrial Fibrillation (AF)142
- Acute Ischemic Stroke139
- Pulmonary Hypertension101
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Minnesota121
- Illinois120
- Maryland120
- Texas118
Recruiting studies9,998 total
- NCT06569940Recruiting
Contactless sleep monitoring device vs standard monitors
This study compares a new contactless device (Sleepiz One+) to standard equipment that measures breathing and heart activity. It is for adults both with and without chronic health conditions.
Zurich, Canton of ZurichAges 18 years+ - NCT06570473RecruitingPhase 2
RV failure treatment trial for pulmonary hypertension patients
This trial is testing two heart medications, empagliflozin and ranolazine, to see if they can improve right heart function in people with pulmonary hypertension and right ventricular failure. Participants will monitor their symptoms using a smartphone or tablet.
Calgary, AlbertaAges 18 years+ - NCT06570460RecruitingPhase 4
Estrogen pills vs. patch for Turner syndrome
This study compares two ways of taking estrogen (pills or a skin patch) in women with Turner syndrome to see which works better over time. It also includes healthy women for comparison.
Aarhus, Aarhus NAges 18–50 - NCT06570681Recruiting
Video call assessment for acute stroke
This trial tests whether a video call with a doctor can help assess stroke symptoms quickly in the ambulance or emergency setting. It aims to see if this approach speeds up care and improves outcomes for people with possible stroke.
Aabenraa, Region SyddanmarkAges 18 years+ - NCT06570902Recruiting
Heart monitor vest after first bypass surgery
This study tests a wearable heart monitor vest (WCD) for people who have had their first coronary bypass surgery and have a weakened heart pump (ejection fraction below 35%). The vest watches for dangerous heart rhythms and can shock the heart back to normal if needed.
Bad Nauheim, HesseAges 18 years+ - NCT06571162Recruiting
Study on LDL cholesterol management for heart disease patients
This study tests whether a clinical pharmacist-led team can help manage LDL cholesterol levels in patients with heart or blood vessel disease. It aims to improve care for people with conditions like coronary artery disease, stroke, or peripheral artery disease.
Salt Lake City, UtahAges 18 years+ - NCT06571552Recruiting
Comparing two blood filtering methods' effect on clotting
This study compares two ways of filtering your blood (plasmapheresis) to see how each affects your blood's ability to clot. If you already receive regular plasmapheresis with citrate, you might help doctors learn which method is safer for you.
NîmesAges 18 years+ - NCT06571721Recruiting
Almond oil vs. tretinoin for face wrinkles in certain women
This study compares a topical almond oil cream to tretinoin to see which reduces facial wrinkles better. It is for post-menopausal women with light to medium skin tones who have fine lines and wrinkles.
Sacramento, CaliforniaAges 18 years+ - NCT06572085RecruitingPhase 4
Butylphthalide for brain protection after cardiac arrest
This trial tests a medicine called butylphthalide (NBP) to see if it helps protect the brain after a cardiac arrest. It is for adults who remained unconscious after their heart was restarted.
Beijing, Beijing MunicipalityAges 18–80 - NCT06572267RecruitingPhase 2
Meplazumab for coronary artery disease
This trial tests if meplazumab can help people with chronic coronary syndrome who have stable angina. It focuses on patients with certain fatty deposits around their heart arteries that show up on a special CT scan.
Xi'an, ShannxiAges 18 years+ - NCT06572605RecruitingPhase 1/Phase 2
Radiation plus talquetamab for myeloma outside the bone
This trial tests combining radiation therapy with a targeted drug called talquetamab for multiple myeloma that has formed tumors outside the bone (extramedullary disease). It aims to see if this combination can shrink or control these tumors and improve outcomes.
Duarte, CaliforniaAges 18 years+ - NCT06572709Recruiting
Ultrasound of rib muscles in stroke survivors
This study uses an ultrasound to look at the small muscles between your ribs (parasternal intercostal muscles) in people who have had a stroke. It aims to understand whether stroke affects these breathing muscles, which might guide future rehabilitation.
IstanbulAges 30–90 - NCT06573242Recruiting
Home heart rehab for heart failure and caregivers
This trial tests a home-based heart rehab program for people with heart failure and their caregivers. It aims to help you manage your condition with support at home, instead of traveling to a center.
Herlev, copenhagenAges 18 years+ - NCT06573359Recruiting
Expanded rehab scale study for stroke survivors
This study aims to test a new scale that measures rehabilitation complexity for stroke patients. It could help doctors better plan your rehab.
Istanbul, BahçelievlerAges 2 months–6 months - NCT06573437Recruiting
VESTO vascular stent for leg artery blockages
This study tests a new stent (a tiny mesh tube) to open blocked arteries in the pelvis or thigh area. It may help improve blood flow and reduce leg pain or wounds.
Salvador, Estado de BahiaAges 18 years+ - NCT06573554Recruiting
Comparing two casts for Charcot foot healing
This study compares two ways to take weight off a Charcot foot (a diabetic foot complication) — a special contact cast versus a removable back slab. The goal is to see which method helps your foot heal better.
ChandigarhAges 18 years+ - NCT06573723Recruiting
Rare disease registry at Hospital Italiano
This study collects information from patients with certain rare diseases to better understand them. If you have one of these conditions and receive care at Hospital Italiano de Buenos Aires, you may be able to join.
Buenos Aires, Buenos AiresAges Any age - NCT06573853Recruiting
Comparing two types of ablation for fast heart rhythm
This trial compares two ablation methods (pulsed field vs. radiofrequency) to treat a fast heart rhythm called PSVT. It aims to see which works better and has fewer risks.
Ningbo, ZhejiangAges 18–80 - NCT06573892Recruiting
Gut Bacteria and Chronic Heart Failure
This study looks at how the bacteria in your gut (the microbiome) relates to chronic heart failure. Researchers want to see if certain probiotics (friendly bacteria) might help people with heart failure feel better.
AstanaAges 18 years+ - NCT06574568RecruitingPhase 1
Study of YKST02 for relapsed or refractory multiple myeloma
This study tests a new drug called YKST02 for people with multiple myeloma that has come back or hasn't responded to other treatments. The goal is to see if it can help when other therapies have stopped working.
Beijing, Beijing MunicipalityAges 18–75 - NCT06574737Recruiting
Can muscle signals predict arm recovery after stroke?
This study tests whether a simple muscle signal test (called surface EMG) can predict how well your arm will recover after a stroke. It involves placing small stickers on your skin to measure muscle activity while you try to move your affected arm.
Bandung, West JavaAges 18 years+ - NCT06575140Recruiting
Stroke recovery arm stimulation study
This study tests a noninvasive stimulation technique to help improve arm movement in people who recently had a stroke. It is for those who still have some ability to move their fingers but have significant weakness on one side.
Mexico CityAges 18–79 - NCT06575270Recruiting
Study of skin color and pulse oximeters in children with heart disease
This trial checks how well pulse oximeters (devices that measure oxygen levels) work in children with congenital heart disease who have different skin colors. It aims to make sure these devices are accurate for all children during heart surgery.
New York, New YorkAges Up to 18 years - NCT06575881Recruiting
Genetic heart muscle disease and heart rhythm study
This study looks at the risk of a fast heart rhythm (ventricular tachycardia) in people with genetic heart muscle diseases. It tests whether having a specific genetic change affects the success of a heart ablation procedure.
Nashville, TennesseeAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,001 recruiting cardiology studies from the U.S. registry right now, out of 15,328 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
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- Mental health
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- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.