Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,001 recruiting studies in this area right now.
By phase
- Not applicable7,980
- Phase 2482
- Phase 4481
- Phase 3447
- Phase 1360
- Phase 1/Phase 2163
- Phase 2/Phase 388
Top conditions
- Stroke846
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation268
- Ischemic Stroke200
- Atrial Fibrillation (AF)142
- Acute Ischemic Stroke139
- Pulmonary Hypertension101
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Minnesota121
- Illinois120
- Maryland120
- Texas118
Recruiting studies9,998 total
- NCT06576089Recruiting
Stroke recovery rehab trial testing Maraviroc vs. placebo
This trial tests if the drug Maraviroc (compared to a placebo) can improve stroke recovery when added to standard rehabilitation. It is for people who have had a specific type of stroke (ischemic anterior circulation) and have weakness on one side of the body, and are already in inpatient rehab.
Calgary, AlbertaAges 18 years+ - NCT06576466Recruiting
Creatine for stroke recovery
This study tests whether taking a daily creatine supplement for a few weeks can help people recover movement better after a recent clot-caused stroke. If you've had a stroke in the past 1 to 5 days and need rehab for weakness or coordination issues, you may be able to join.
Palma de Mallorca, Balearic IslandsAges 18–80 - NCT06576752Recruiting
Home heart failure management after hospital discharge
This trial tests a program to manage heart failure at home after you leave the hospital. It aims to safely adjust your medications to optimal doses while you recover at home.
Lørenskog, AkershusAges 18 years+ - NCT06577519RecruitingPhase 3
Study of vicagrel for heart attack patients getting stents
This trial tests a new medicine called vicagrel for people who have had a heart attack or unstable angina and are getting a stent. The goal is to see if it works better than standard treatments to prevent future heart problems.
Shenyang, LiaoningAges 18–80 - NCT06578078RecruitingPhase 3
Best heart failure care for older patients with kidney disease
This study tests the best way to manage heart failure in older adults who also have kidney problems and high potassium levels. It compares different treatment strategies to see which one is safest and most effective.
Alcorcón, MadridAges 70 years+ - NCT06577896Recruiting
Onyx stent safety and effectiveness in older adults
This study looks at how well a specific brand of heart stent (Onyx) works in people 75 and older who have narrowed heart arteries. If you've already received an Onyx stent, the study will check its safety and effectiveness over time.
Yangsan, Gyeongsangnam-doAges 75–100 - NCT06578234RecruitingPhase 4
Comparing Adenosine Doses for Heart MRI
This study will compare different doses of adenosine during a heart MRI to find the best dose for measuring blood flow to the heart muscle. It is for people with known or possible coronary artery disease or heart failure, as well as healthy volunteers.
LundAges 40 years+ - NCT06578520RecruitingPhase 4
Testing dapagliflozin for heart failure on dialysis
This trial tests whether adding dapagliflozin (a medication that helps protect the heart and kidneys) helps people with heart failure who are also on peritoneal dialysis. It may offer extra support for your heart and kidney health.
ValenciaAges 18 years+ - NCT06578689Recruiting
Diabetes foot problems study in Jordan
This study looks at why people with diabetes develop foot problems and how these problems affect their lives. It is being done in Jordan and uses a phone survey to collect information.
IrbidAges 18–90 - NCT06578793Recruiting
Catheter plus vein ablation for atrial fibrillation with heart failure
This trial tests whether adding a vein ablation to standard catheter ablation helps people with persistent atrial fibrillation and heart failure. It aims to find the best treatment to improve heart function and reduce symptoms.
Changsha, HunanAges 18–80 - NCT06579807Recruiting
Cardiac rehab for coronary artery disease
This study tests if a cardiac rehabilitation program helps people with coronary artery disease. You can join if you are between 40 and 70, have heart disease (or are a healthy volunteer), and do not have other health issues like heart failure or smoking.
Rio de Janeiro, Rio de JaneiroAges 40–70 - NCT06579664Recruiting
Brain stimulation for memory loss from small vessel disease
This trial tests whether a type of non-invasive brain stimulation called intermittent theta burst stimulation can improve memory and thinking in people whose cognitive problems are caused by cerebral small vessel disease (damage to the small blood vessels in the brain). You may qualify if you have mild memory or thinking issues that have lasted at least three months.
BeijingAges 45–80 - NCT06579677Recruiting
Watching small blood vessels in the brain over time
This study watches how small blood vessels in the brain change over time. It may help doctors understand brain health as people age.
Beijing, Beijing MunicipalityAges 50–75 - NCT06580158Recruiting
AI for diagnosing heart valve and pump problems
This trial is testing how well an AI tool can help doctors diagnose aortic stenosis and diastolic dysfunction by analyzing your scheduled ECG (heart test). The study takes place during your routine care at the clinic.
Rochester, MinnesotaAges 60 years+ - NCT06580392Recruiting
CCM device plus medications for heart failure with low pump strength
This study tests a heart device (CCM) plus standard medications to see if the combination helps people with a weak heart pump. It's for those whose heart function is low and who still have symptoms despite current treatment.
Rome, ItalyAges 18 years+ - NCT06580613Recruiting
Better blood pressure management in primary care
This trial tests a new way to manage high blood pressure in primary care. It aims to help people better control their blood pressure using home monitoring and digital tools.
HelsingborgAges Any age - NCT06580652Recruiting
Comparing airway devices during in-hospital cardiac arrest
This trial is comparing different ways to manage the airway (how you breathe) during a cardiac arrest that happens inside the hospital. It helps doctors decide which type of breathing device works best in an emergency.
Bath, BanesAges 18 years+ - NCT06580717RecruitingPhase 4
Testing empagliflozin for heart stiffness in hypertrophic cardiomyopathy
This study tests whether a diabetes drug (empagliflozin) can improve the heart's ability to relax and fill with blood in people with non-obstructive hypertrophic cardiomyopathy, a type of heart muscle thickening. You may be able to join if you have this condition and are not currently taking an SGLT2 inhibitor.
SeoulAges 19–80 - NCT06581471Recruiting
New device for severe leaky heart valve
This study tests a new device to fix a leaky tricuspid valve without open-heart surgery. It is for people with severe leakage who are considered too high-risk for traditional surgery.
AalstAges 18 years+ - NCT06581484Recruiting
Improving care for adults with congenital heart disease
This study aims to improve care for adults with congenital heart disease. If you join, researchers will work to better understand your needs and help enhance your treatment.
San Francisco, CaliforniaAges 18 years+ - NCT06581562RecruitingPhase 1
Testing rituximab plus AB-101 for autoimmune diseases
This trial tests a new treatment (AB-101) combined with rituximab for people with certain autoimmune diseases like rheumatoid arthritis, pemphigus vulgaris, vasculitis, or lupus. It is for those who have not had success with standard therapies.
Plantation, FloridaAges 18 years+ - NCT06581640RecruitingPhase 2
BCMA-targeting CAR-T cells for relapsed/refractory myeloma
This trial tests a new type of immune cell therapy (CAR-T cells) that targets a protein called BCMA on multiple myeloma cells. It is for people whose myeloma has come back or has not responded to other treatments.
Xiamen, FujianAges 18–80 - NCT06582316Recruiting
Digital program for brain health in midlife
This study tests a digital program to help improve brain health in people aged 40–55 who have high blood pressure, high cholesterol, or type 2 diabetes. It uses an app and online sessions to offer tips and support for keeping your thinking skills sharp.
SingaporeAges 40–64 - NCT06582472Recruiting
Early eye changes and diabetes trial
This study looks at early damage to the retina (the back of the eye) in people with type 2 diabetes, even before vision problems start. It aims to find new ways to detect and treat diabetic eye disease early.
Milan, Italy/milanAges 40–80
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,001 recruiting cardiology studies from the U.S. registry right now, out of 15,328 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.