Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,008 recruiting studies in this area right now.
By phase
- Not applicable7,984
- Phase 2484
- Phase 4481
- Phase 3449
- Phase 1360
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke846
- Heart Failure563
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease371
- Multiple Myeloma331
- Atrial Fibrillation271
- Ischemic Stroke200
- Atrial Fibrillation (AF)143
- Acute Ischemic Stroke141
- Pulmonary Hypertension101
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic84
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California467
- Alabama197
- Massachusetts182
- Arizona174
- New York163
- Florida143
- Minnesota121
- Maryland120
- Illinois119
- Texas118
Recruiting studies10,005 total
- NCT06736899Recruiting
Orbital atherectomy versus standard care for calcified branch blockages
This trial compares a special device called orbital atherectomy to the usual procedure for treating hardened, calcified blockages that occur where a coronary artery branches. It aims to see which approach works better for patients needing a stent.
AlicanteAges 18 years+ - NCT07296744Recruiting
Study of a heart pump for high-risk angioplasty
This trial tests a new device called the Supira system to support the heart during a high-risk procedure to open blocked arteries. It is for people who are stable enough to wait for the procedure (not in emergency or shock).
Loma Linda, CaliforniaAges 18–90 - NCT01311323Recruiting
Testing heart procedures to fully open blocked coronary arteries
This trial compares different ways to treat serious heart artery blockages in people with a recent heart attack or unstable chest pain. It aims to see which revascularization approach works best when doctors think the heart arteries can be fully treated.
Chrzanów, MalopolskaAges 18 years+ - NCT07649135Recruiting
Remote Step-Counting Program for Stroke Recovery
This study tests whether a remote (at-home) program that tracks your daily steps and includes support from someone you know can help you become more physically active after a stroke. Researchers want to see if this approach is practical and if it helps people who had a stroke 6+ months ago move more.
Minneapolis, MinnesotaAges 18 years+ - NCT06601127RecruitingPhase 2
Tiprogrel for recent minor stroke or high-risk TIA
This trial tests a new anti-platelet drug called Tiprogrel to prevent another stroke in people who recently had a minor stroke or a transient ischemic attack (TIA) with certain artery narrowing or plaques. It aims to see if this medicine is safe and works better than current treatments.
Shenyang, LiaoningAges 40 years+ - NCT06601153Recruiting
Heart health study using CT scans and blood samples
This study looks at blood samples and CT scans from people with stable coronary artery disease to find new ways to predict and prevent future heart problems. If you've had or are about to have a cardiac CT and have blood stored, you might be able to join.
Pisa, ItalyAges 40–75 - NCT06601842Recruiting
Brain blood flow monitoring after cardiac arrest
This study tests a way to monitor blood flow to the brain after a cardiac arrest that was not caused by trauma. It aims to help doctors find the best blood pressure to support brain recovery in the ICU.
TaipeiAges 18 years+ - NCT06601998Recruiting
Heart health after severe pneumonia
This study looks at how heart health changes in people who have recovered from severe pneumonia, including COVID-19. It compares survivors to healthy people and those with heart risk factors.
AlexandroupoliAges 18 years+ - NCT06602609Recruiting
Remote heart monitoring after TAVI valve procedure
This trial tests whether patients can go home the same day after TAVI and use a smart device for remote monitoring. It aims to see if this approach is safe and effective for recovery.
LondonAges 18 years+ - NCT06602635Recruiting
New scoring system for outflow tract arrhythmias with wide QRS
This study is testing a new scoring system (called a Hybrid Score) to better predict the origin of ventricular arrhythmias coming from the outflow tract of the heart. The goal is to improve treatment planning for people with a wide QRS complex on their ECG.
Brussels, BelgiumAges 18 years+ - NCT06603363Recruiting
Statin effects on heart artery plaques seen on CT scans
This trial studies how short-term statin therapy changes plaque buildup in heart arteries. It uses CT scans to see if statins can make plaques more stable and reduce heart risks.
Budapest, BudapestAges 45–75 - NCT06603454Recruiting
Chest CT before aortic valve replacement surgery
This study looks at whether a CT scan of the chest before aortic valve replacement surgery (with or without bypass) can help doctors plan the procedure better. It is for people with severe aortic valve stenosis who are already scheduled for surgery.
Nieuwegein, UtrechtAges 18 years+ - NCT06603870RecruitingPhase 4
Preventing blood clots in cancer patients with catheter-related clots
This study tests whether a lower dose of the blood thinner apixaban (Eliquis) can safely prevent another blood clot in people with cancer who have a catheter-related clot in their upper arm or neck. It aims to find a balance between preventing clots and reducing bleeding risk.
Ottawa, OntarioAges 18 years+ - NCT06604143Recruiting
Hand and finger recovery after stroke
This study tests whether a hand exercise program can improve movement in people who had a stroke more than 6 months ago. It aims to help you regain control of your hand and fingers.
Toronto, OntarioAges 19–80 - NCT06604117Recruiting
Probucol and statins for recent ischemic stroke
This trial tests whether adding probucol to statin therapy can help people who recently had an ischemic stroke caused by hardened arteries. The goal is to see if this combination works better than statins alone for preventing future strokes.
Xicheng District, Beijing MunicipalityAges 18 years+ - NCT06604468Recruiting
Portable chest device for detecting lung fluid in heart failure
This trial tests a small, portable device worn on the chest that measures changes in fluid levels in your lungs to help detect early signs of fluid buildup (pulmonary congestion). This could help people with heart failure avoid emergency hospital visits.
Montreal, QuebecAges 18 years+ - NCT06604650Recruiting
Park-based health program for older adults in Miami
This study looks at how community park programs can help older adults stay healthy. It will use information already collected from people who are already part of the Miami-Dade Active Older Adults study.
Miami, FloridaAges 50–95 - NCT06605014Recruiting
Body alignment after stroke or mini-stroke
This study looks at how a stroke or mini-stroke affects the body's natural movement and alignment (called somatic dysfunction). Researchers want to see if there are common patterns of tightness or imbalance after a stroke, which could help guide future treatments.
Sacramento, CaliforniaAges 18 years+ - NCT06605209Recruiting
A covered stent study for iliac artery blockage
This trial tests a balloon-expandable covered stent to treat blockages in the iliac artery (a major blood vessel in your pelvis). It may be an option for people with leg pain from poor blood flow.
Beijing, Beijing MunicipalityAges 18–80 - NCT06606210Recruiting
Testing a pig skin wound treatment for hard-to-heal leg ulcers
This trial tests if adding a special wound dressing made from pig placenta to standard care helps heal leg ulcers faster than standard care alone. You may qualify if you have a leg ulcer that has not shown much improvement in the last 4 weeks.
North Port, FloridaAges 21 years+ - NCT06606821RecruitingPhase 4
Tirzepatide for heart health in people with overweight or obesity
This trial tests the weight‑loss medication tirzepatide (Mounjaro) in people who are overweight or have obesity and have stable coronary artery disease. The goal is to see if tirzepatide can reduce dangerous fatty plaque in heart arteries.
CopenhagenAges 18 years+ - NCT06607471Recruiting
Study on non-ischemic heart muscle diseases
This study looks at different types of heart muscle diseases that are not caused by blocked arteries (non-ischemic cardiomyopathies). It aims to better understand how to diagnose, predict outcomes, and treat these conditions by gathering information from many patients over time.
Milan, MilanoAges 18 years+ - NCT06608771Recruiting
Outcomes of cardiac arrest patients over the years
This trial looks at how well patients do after a cardiac arrest, focusing on how care has improved over time following new guidelines. It aims to find better ways to help people who survive a cardiac arrest.
Monza, Monza E BrianzaAges 18 years+ - NCT06609668Recruiting
Thrombomodulin blood test to rule out giant cell arteritis in PMR
This study tests whether a blood test for a protein called thrombomodulin can help rule out giant cell arteritis (a blood vessel inflammation) in people with polymyalgia rheumatica. It involves a blood draw and a one-time imaging scan to look at your blood vessels.
DijonAges 50 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,008 recruiting cardiology studies from the U.S. registry right now, out of 15,355 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.