Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,008 recruiting studies in this area right now.
By phase
- Not applicable7,984
- Phase 2484
- Phase 4481
- Phase 3449
- Phase 1360
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke846
- Heart Failure563
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease371
- Multiple Myeloma331
- Atrial Fibrillation271
- Ischemic Stroke200
- Atrial Fibrillation (AF)143
- Acute Ischemic Stroke141
- Pulmonary Hypertension101
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic84
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California467
- Alabama197
- Massachusetts182
- Arizona174
- New York163
- Florida143
- Minnesota121
- Maryland120
- Illinois119
- Texas118
Recruiting studies10,005 total
- NCT07115940Recruiting
Clot removal after 24 hours for stroke patients
This trial tests if removing a large blood clot from the brain up to 3 days after a stroke improves recovery compared to standard medical care alone. It is for patients who have a severe stroke and are otherwise healthy enough for the procedure.
Chicago, IllinoisAges 18–85 - NCT07228312Recruiting
Stent treatment for unruptured brain aneurysm
This study tests a flexible stent (Choydar flow-directed mesh) to treat unruptured brain aneurysms in the neck area of the carotid or vertebral arteries. It is for people whose aneurysm has not bled and fits certain size and shape limits.
ChenzhouAges 18 years+ - NCT07354477RecruitingPhase 2
New eye drop for glaucoma and diabetic retinopathy
This trial tests a new eye drop (QLS-111) to see if it improves blood flow in the back of the eye. It may help people with mild to moderate glaucoma or stable diabetic retinopathy by reducing pressure inside the eye and nourishing the optic nerve.
Palo Alto, CaliforniaAges 18 years+ - NCT07569887Recruiting
Brain Imaging Study of Arteriovenous Malformations Before and After Surgery
This research study uses special brain imaging scans to understand how an unruptured arteriovenous malformation (an abnormal tangle of blood vessels in the brain) affects blood flow and thinking abilities before and after surgical treatment. The goal is to learn how surgery impacts brain function and cognition in patients like you.
Montpellier, FranceAges 18 years+ - NCT07491510Enrolling by invitation
Reducing early preeclampsia risk in low-income pregnancy care
This study tests whether adding doula support to prenatal care can lower the chance of developing preeclampsia (dangerously high blood pressure in pregnancy). It is for people who are early in pregnancy and have moderate or high risk for this condition.
Kansas City, KansasAges 18–45 - NCT07403760Recruiting
Ablation for atrial fibrillation in patients 80 and older
This study investigates whether a catheter ablation procedure can improve wellbeing and reduce the risk of serious events for people 80 and older with symptomatic atrial fibrillation. The goal is to see if this treatment offers better outcomes than standard care in this age group.
BeijingAges 80 years+ - NCT07245927Recruiting
Staphylokinase for massive pulmonary embolism with shock
This trial tests a single injection of a clot-busting drug called staphylokinase for people with a massive pulmonary embolism that is causing shock or very low blood pressure. It aims to see how well the drug works in this emergency situation.
BelgorodAges 18 years+ - NCT07560982Recruiting
Improving medication adherence in advanced heart failure
This study looks at whether patients with severe heart failure follow their prescribed medications as recommended by treatment guidelines. The researchers want to understand what helps or prevents patients from taking their medicines correctly, which could improve their heart function and symptoms.
BergamoAges 18–75 - NCT07428473RecruitingPhase 1
Study of STX-1150 for high cholesterol
This early-phase trial tests a new medication called STX-1150 for people with high LDL cholesterol. It aims to see if the drug is safe and how well it works to lower cholesterol.
Clayton, VictoriaAges 18–70 - NCT07688863Enrolling by invitation
Comparing breathing muscle training methods for heart failure
This trial compares two different types of breathing muscle training to see which works better for people with heart failure and weak breathing muscles. You may join if you have heart failure with reduced pumping ability and are stable overall.
Viña del Mar, ValparaisoAges 18 years+ - NCT07377383Recruiting
Exercise for heart health in postmenopausal women
This study tests how different exercise routines affect heart and metabolic health in women after menopause. It may help if you are already active, have few heart risk factors, and are not on hormone therapy.
Oleiros, A CoruñaAges 46–65 - NCT07494890Recruiting
Walking test study for stroke survivors with slow walking
This study looks at how we measure the effort of walking in people who have had a stroke and still walk slowly. It may help understand your walking and guide better treatments.
Cincinnati, OhioAges 30–80 - NCT07447908Recruiting
Understanding worsening heart failure after leaving the hospital
This study monitors heart failure patients after a hospital stay or urgent clinic visit to better understand the signs of worsening heart failure. It may help researchers find ways to predict and prevent future exacerbations.
Newmarket, OntarioAges 18 years+ - NCT06995625RecruitingPhase 1
Stem cell particles for recent stroke recovery
This trial tests whether stem cell-derived extracellular vesicles can help people recover after a moderate to severe stroke. You may join if you had a stroke in the last 5 days and still have arm or leg weakness, even after standard treatments like clot-busting drugs or clot removal.
Suwon, Gyeonggi-doAges 19 years+ - NCT07451028Recruiting
Mouth training device for swallowing problems after stroke
This trial tests a device that strengthens mouth muscles to help people who have trouble swallowing after their first stroke. It may improve your ability to swallow safely.
Hammel, JutlandAges 18 years+ - NCT07477613Recruiting
Brain implant for arm recovery after stroke
This trial tests a brain-computer interface (a device implanted in the brain) to help people who have had a stroke regain arm movement. It may help if you have a single stroke that happened 6 to 18 months ago and still have trouble using your arm.
GrenobleAges 18–70 - NCT07210151Recruiting
Imaging Catheter for Heart Ablation Procedures
This study tests a new imaging catheter (VERAFEYE) to help doctors guide ablation procedures for atrial flutter or atrial fibrillation. It may lead to safer, more precise treatment of these heart rhythm problems.
SplitAges 18 years+ - NCT07635407Recruiting
Virtual Stent Planning to Improve Heart Artery Procedures
This trial tests whether using computer software to virtually plan stent placement before your heart procedure leads to better outcomes. The goal is to optimize how stents are positioned in your coronary arteries.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07636642Recruiting
New Heart Attack Blood Test Accuracy Study
This study compares two versions of a sensitive heart attack blood test to see how well the newer version can quickly rule out heart attacks in the emergency department. You'll have blood drawn as part of your normal care, and researchers will review your medical records.
Edinburgh, MidlothianAges 18 years+ - NCT07619820RecruitingPhase 1
CSL300 Safety Study for Kidney Dialysis Patients
This study tests how a new drug called CSL300 (clazakizumab) works in the body of people with end-stage kidney disease who are on dialysis. Researchers want to understand if it's safe and how your body processes it.
BeijingAges 18 years+ - NCT07001800RecruitingPhase 2/Phase 3
Slowing aortic valve disease with ataciguat
This trial tests a new pill, ataciguat, to slow down the progression of moderate calcific aortic valve stenosis (a condition where your aortic valve stiffens). If you have moderate valve narrowing and meet the other criteria, participation could help find a way to delay needing surgery.
Birmingham, AlabamaAges 50 years+ - NCT06708299RecruitingPhase 3
CardiolRx for recurrent pericarditis
This trial tests if CardiolRx can help people with recurrent pericarditis (inflammation of the heart lining) who are stable on an IL-1 blocker and are planning to stop it. Researchers will see if CardiolRx can prevent a recurrence when the current treatment is tapered off.
Phoenix, ArizonaAges 18 years+ - NCT06709950Recruiting
Art therapy for movement recovery after stroke
This study tests art therapy (like painting or clay) to help improve movement and emotional well-being after a recent stroke. It is designed for people in the subacute phase (2 weeks to 3 months after their first stroke) who have mild to moderate physical challenges and can actively participate in creative activities.
Jiamusi, HeilongjiangAges 40–75 - NCT06709898Recruiting
Returning to work after a stroke
This study looks at how job accommodations can help people return to work after a stroke. It focuses on those who had a stroke within the last year and have some thinking or emotional symptoms.
Helsinki, UusimaaAges 18–68
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,008 recruiting cardiology studies from the U.S. registry right now, out of 15,355 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
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- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.