Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,008 recruiting studies in this area right now.
By phase
- Not applicable7,984
- Phase 2484
- Phase 4481
- Phase 3449
- Phase 1360
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke846
- Heart Failure563
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease371
- Multiple Myeloma331
- Atrial Fibrillation271
- Ischemic Stroke200
- Atrial Fibrillation (AF)143
- Acute Ischemic Stroke141
- Pulmonary Hypertension101
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic84
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California467
- Alabama197
- Massachusetts182
- Arizona174
- New York163
- Florida143
- Minnesota121
- Maryland120
- Illinois119
- Texas118
Recruiting studies10,005 total
- NCT06710938Recruiting
Stent graft for thoracoabdominal aortic aneurysm
This trial tests a new stent graft system for treating a thoracoabdominal aortic aneurysm, a bulging of the main blood vessel in your chest and belly. It may be an option if your aneurysm is large, growing, or causing pain and you are healthy enough for the procedure.
HamburgAges 18–80 - NCT06711016Recruiting
Managing brain oxygen after emergency life support
This trial tests a targeted approach to manage oxygen levels in the brain for patients who received ECMO (a machine that does the heart and lung work) after a cardiac arrest that did not respond to standard CPR. The goal is to improve brain recovery and outcomes.
Jinan, ShandongAges 18–75 - NCT06711003Recruiting
Enhanced circulation therapy for recent stroke recovery
This trial tests whether a non-invasive treatment that boosts blood flow can help people recovering from a stroke. If you had a stroke within the last month and have moderate to moderately severe disability, you may be eligible to participate and potentially improve your recovery.
TaichungAges 20 years+ - NCT06711120Recruiting
Comparing two treatments for varicose veins in the lower legs
This study compares two minimally invasive treatments (radiofrequency ablation and microwave ablation) for varicose veins in the small saphenous vein. If your varicose veins cause symptoms like pain, swelling, or heaviness, this trial may help determine which treatment works better.
ChengduAges 18–90 - NCT06711432Recruiting
Blood Pressure Management During Tumor Surgery and Brain Function
This trial compares different blood pressure management strategies during abdominal tumor surgery to see which one better protects cognitive function (thinking, memory, and clarity). It is for patients who have multiple stroke risk factors and are undergoing a lengthy surgery.
Hangzhou, ZhejiangAges 40–85 - NCT06711705RecruitingPhase 2
Elranatamab for relapsed or refractory multiple myeloma
This study tests a new drug called elranatamab for people with multiple myeloma that has come back or not responded to previous treatments. Elranatamab is a type of immunotherapy that targets a protein on myeloma cells to help your immune system fight the cancer.
La Jolla, CaliforniaAges 18 years+ - NCT06712004RecruitingPhase 2
Testing a new stroke drug: different doses for people who cannot get standard care
This trial tests a new medication (bevifibatide) to see which dose works best for people having an ischemic stroke who cannot get standard treatments like clot-busting drugs or a procedure to remove the clot. It aims to improve recovery by stopping clots from getting worse.
Guangzhou, GuangdongAges 18–80 - NCT06712186RecruitingPhase 1/Phase 2
Dexmedetomidine for safer intubation in high blood pressure patients
This study tests if dexmedetomidine can help prevent dangerous blood pressure spikes during breathing tube placement for surgery in patients with high blood pressure. It is for older adults (over 60) who have been managing their hypertension for at least 6 months.
Karachi, SindhAges 60 years+ - NCT06712810RecruitingPhase 1
Q702 for blood cancers and histiocytic disorders
This study tests an experimental pill called Q702 for people with certain blood cancers and related disorders (like histiocytoses, myelofibrosis, and lymphomas) that have not responded to standard treatments. It aims to see if Q702 is safe and effective.
Scottsdale, ArizonaAges 18 years+ - NCT06712862Recruiting
Testing heart muscle health with PET/MR scan
This study uses a special imaging test (PET/MR) to check if damaged heart muscle is still alive and can recover. It is for people with severe blocked arteries and weak heart pumping function who are planning bypass surgery or stem cell treatment.
Shanghai, Shanghai MunicipalityAges Up to 80 years - NCT06713252Recruiting
Art therapy for stroke recovery
This study tests whether art therapy can help improve non-motor symptoms (like mood and thinking) during the early recovery phase after a stroke. Participants will attend art sessions while continuing their regular rehab.
Jiamusi, HeilongjiangAges 40–75 - NCT06713720Recruiting
Arm Cuff Therapy for Early Diabetic Eye Disease
This study tests if a simple, non-invasive treatment called remote ischemic conditioning (briefly restricting blood flow to one arm using a special cuff) can help slow down early-stage diabetic eye disease in people with type 2 diabetes. You join the study to potentially prevent your retinopathy from getting worse.
Beijing, Beijing MunicipalityAges 40–80 - NCT06713850Recruiting
Balloon treatment for leg artery blockages with calcium
This trial uses a special balloon (Shockwave IVL) to break up calcium in leg artery blockages, improving blood flow and reducing pain. It's for people with moderate to severe calcium buildup in the femoropopliteal artery.
Wuhan, HubeiAges 18 years+ - NCT06713889Recruiting
Study of heart valve disease and events
This study looks for biological markers in the blood that might help predict heart-related events in people with a narrowed aortic heart valve. It aims to improve care for those with this condition, whether or not they have a procedure called TAVI to replace the valve.
LyonAges 18 years+ - NCT06713993Recruiting
Esophageal Cancer Study: Using Noninvasive Tests to Guide Care
This study is looking for people newly diagnosed with esophageal cancer or cancer at the stomach-esophagus junction who are planning to have surgery. The goal is to see if certain noninvasive tests (like scans) can help predict how the disease will progress.
BudapestAges 18 years+ - NCT06714409Recruiting
Ultrasound-guided fluid removal in hospitalized heart failure
This study tests whether using ultrasound-guided treatment to reduce fluid buildup in the body can help people hospitalized for worsening heart failure feel better faster. It's for adults admitted with heart failure and high BNP levels.
OsloAges 18 years+ - NCT06714344Recruiting
Heart failure therapy support study
This trial tests a new tool to help doctors better manage heart failure treatment. It may be for patients who need IV diuretics for fluid buildup, either in the hospital or at home to avoid hospitalization.
Graz, StyriaAges 18 years+ - NCT06714526Recruiting
Gene test to pick best anti-clot drug for narrowed brain arteries
This trial compares using a genetic test to choose between two anti-clot medications (clopidogrel and ticagrelor) versus the usual approach of giving clopidogrel alone. It aims to see if personalized treatment can better prevent strokes in people with narrowed brain arteries.
Calgary, AlbertaAges 40 years+ - NCT06714565Recruiting
Can blood pressure and brain oxygen predict falls?
This study looks at how measuring blood pressure and oxygen levels in the brain may help predict falls in older adults. If you have fallen before, your participation could help doctors find better ways to prevent future falls.
AmsterdamAges 65 years+ - NCT06714734Recruiting
Blood thinners in cancer patients with blood clots
This study looks at how well blood thinners (anticoagulants) work in people with cancer who have had a blood clot. It aims to compare the benefits and risks of different anticoagulant medicines.
BolognaAges 18 years+ - NCT06715046Recruiting
Blood DNA test after stem cell transplant
This study checks if looking at DNA in your blood can help doctors see how well your stem cell transplant is working and catch any problems early. It is for people with blood cancers getting a transplant from a donor.
Milan, MilanAges 18 years+ - NCT06715007Recruiting
Study on blood thinners and artery health for small vessel stroke
This study tests whether a combination of antiplatelet drugs and artery-stabilizing medication can improve recovery after a small stroke caused by damage to tiny blood vessels in the brain. It may help prevent further strokes and support healing.
Nanjing, JiangsuAges 30–79 - NCT06717113RecruitingEarly Phase 1
A new imaging test for multiple myeloma
This trial tests a special imaging dye that targets a protein called BCMA on multiple myeloma cells. It may help doctors see and diagnose the disease more clearly during bone marrow or tissue biopsies.
Beijing, Beijing MunicipalityAges 18–80 - NCT06717581Recruiting
Drug interaction study for older people with HIV
This study looks at how other medicines you take for conditions like high blood pressure, diabetes, or cholesterol might interact with your HIV medication (Biktarvy) if you are 60 or older. The goal is to learn how to better manage your overall health.
BolognaAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,008 recruiting cardiology studies from the U.S. registry right now, out of 15,355 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.