Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,066 recruiting studies in this area right now.
By phase
- Not applicable8,037
- Phase 2488
- Phase 4482
- Phase 3452
- Phase 1360
- Phase 1/Phase 2161
- Phase 2/Phase 386
Top conditions
- Stroke856
- Heart Failure566
- Hypertension403
- Cardiovascular Diseases390
- Coronary Artery Disease375
- Multiple Myeloma329
- Atrial Fibrillation273
- Ischemic Stroke199
- Atrial Fibrillation (AF)146
- Acute Ischemic Stroke141
- Pulmonary Hypertension104
- Myocardial Infarction98
- Congenital Heart Disease87
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome83
- Obesity80
- Aortic Valve Stenosis78
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital54
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California467
- Alabama198
- Massachusetts181
- Arizona176
- New York166
- Florida145
- Illinois120
- Maryland120
- Texas120
- Minnesota119
Recruiting studies10,063 total
- NCT07575984RecruitingPhase 4
Mexidol Safety and Efficacy for Acute Ischemic Stroke
This trial tests whether Mexidol, a medication that may protect brain tissue, can help people recover better after an acute ischemic stroke (a type of stroke caused by a blood clot). The study includes stroke patients and healthy volunteers to understand how the drug works and if it's safe.
ArkhangelskAges 18–90 - NCT07576166Recruiting
Breathing and Balance Training After Stroke
This study tests whether combining rhythmic breathing exercises with balance training can improve balance and trunk control in people recovering from stroke. You'll participate in structured exercises designed to help you regain stability and core strength.
Sargodha, Punjab ProvinceAges 45–65 - NCT07576465Recruiting
Combining Movement Therapy and Electrical Stimulation After Stroke
This trial tests whether combining a specialized movement therapy (SBMT) with electrical nerve stimulation (NMES) can help improve upper arm and hand function in people recovering from stroke. The study focuses on patients 3–6 months after their stroke, when recovery potential is still strong.
Jhang, Punjab ProvinceAges 4.2 years–5.4 years - NCT07576894Recruiting
How the Heart Responds to Exercise in COPD Patients
This study looks at how the right side of your heart responds when you exercise, in people with COPD (a chronic lung condition). The goal is to understand this response better and potentially improve treatments.
Aurora, ColoradoAges 40 years+ - NCT07577206RecruitingEarly Phase 1
New PET Scan Tracer for Advanced Solid Cancers
This early-stage trial tests a new radioactive tracer called [68Ga]Ga-R54 that helps doctors see certain advanced cancers (like breast, lung, colon, ovary, pancreas, or multiple myeloma) on PET scans. The tracer targets a specific protein (CXCR4) found on cancer cells, which may help doctors better detect and understand your cancer.
Naples, ItaliaAges 18 years+ - NCT07577609Recruiting
AI-assisted CT scan to assess heart artery disease risk
This study uses artificial intelligence to analyze your heart CT scan and better predict your risk of coronary artery disease (narrowing of the arteries that supply your heart). The goal is to help doctors identify who might need earlier treatment or more careful monitoring.
GalwayAges 18 years+ - NCT07577700Recruiting
Blood flow imaging study during pulmonary surgery
This study uses a special imaging technique called electrical impedance tomography (EIT) to measure how blood flows through your lungs during surgery for chronic thromboembolic pulmonary hypertension. The goal is to better understand how this imaging tool works and improve outcomes for patients having this procedure.
São Paulo, São PauloAges 18 years+ - NCT07578090Recruiting
Managing high blood pressure, blood sugar, and cholesterol
This study tests a new approach to helping people manage chronic conditions like high blood pressure, high blood sugar, or high cholesterol. Researchers will work with participants to improve their care and quality of life.
New Taipei CityAges 18 years+ - NCT07579026Recruiting
Breathing exercises for pregnant women with POTS
This study tests whether special breathing exercises can help pregnant women with POTS (a condition where your heart races when you stand up). POTS causes dizziness, lightheadedness, and fainting, and this trial aims to see if breathing retraining makes these symptoms better during pregnancy.
Sialkot, Punjab ProvinceAges 19–35 - NCT07579234RecruitingPhase 3
New drug F182112 for hard-to-treat multiple myeloma
This trial tests a new drug called F182112 against standard treatments for multiple myeloma that has stopped responding to previous therapies. The goal is to see if F182112 works better and is safe for patients whose cancer has become resistant to multiple drug classes.
TianjingAges 18 years+ - NCT07579871Recruiting
Sleep patterns and recovery after first stroke
This study looks at how sleep affects recovery in people who have had their first ischemic stroke (a stroke caused by a blood clot). Researchers want to understand whether sleep quality influences how well patients regain function after stroke.
Lund, Skåne CountyAges 18 years+ - NCT07581145RecruitingPhase 3
Semaglutide for Faster Healing of Diabetic Foot Ulcers
This study tests whether a diabetes medication called semaglutide can help foot ulcers heal faster in people with type 2 diabetes. If it works, it could offer a new treatment option for a common and serious diabetes complication.
CopenhagenAges 18–90 - NCT07581210RecruitingPhase 2
QD202 Study for Recent Stroke Treated With Clot-Busting Medicine
This study tests whether a new drug called QD202 can help protect the brain and improve recovery when given alongside standard clot-busting therapy (thrombolysis) for acute ischemic stroke. You would be in the trial if you had a stroke in the last 24 hours and are receiving or planning to receive thrombolytic treatment.
Meizhou, GuangdongAges 18–85 - NCT07581704RecruitingPhase 1
Sirolimus plus immunotherapy for relapsed multiple myeloma
This study tests whether a drug called sirolimus, given before certain immunotherapy treatments (teclistamab or talquetamab), helps these treatments work better against multiple myeloma. These immunotherapies teach your immune cells to attack myeloma cells.
Iowa City, IowaAges 18 years+ - NCT07581808RecruitingPhase 4
Two cholesterol drugs for heart disease prevention
This study tests two newer cholesterol-lowering medications (inclisiran and alirocumab) together in people who've had heart problems or strokes and cannot tolerate standard cholesterol drugs. The goal is to see if this combination safely lowers cholesterol further and reduces future cardiovascular events.
LjubljanaAges 18 years+ - NCT07582354Recruiting
Understanding Multiple Myeloma Differences Between Patients
This study collects information and samples from people with multiple myeloma or related blood disorders to understand why the disease affects people differently. Researchers will use this information to develop better, personalized treatment approaches.
Bologna, BoAges 18 years+ - NCT07582432RecruitingPhase 3
Gamunex for Blood Cancer Patients With Low Antibodies
This trial tests whether Gamunex, an antibody replacement therapy, helps patients with chronic lymphocytic leukemia, multiple myeloma, or non-Hodgkin lymphoma who have low immunoglobulin (antibody) levels. The treatment may reduce infections and improve how well the body fights disease.
St. Petersburg, FloridaAges 18 years+ - NCT07582835RecruitingPhase 3
Long-term heart clot prevention after stent placement
This study tests whether taking a single blood-thinning medication (instead of two) after heart stent placement is safe and effective over the long term. If you've recovered well from a stent procedure, this trial may help determine the safest way to prevent future heart problems.
Lugano, Ch/tiAges 18 years+ - NCT07583940Recruiting
Energy Intake and Blood Pressure in College Athletes
This study looks at whether not eating enough calories affects blood pressure in Division I college athletes. Researchers want to understand if improving nutrition can help prevent high blood pressure in young athletes.
Greensboro, North CarolinaAges 18–26 - NCT07585799Recruiting
Heart Pacing Method for Wide QRS Rhythm Patients
This trial compares two ways to place a heart pacemaker in patients with an abnormally wide heartbeat pattern. Researchers want to see if a newer pacing technique that targets the heart's natural conduction system works better than traditional pacing methods.
Granada, AndalusiaAges 18 years+ - NCT07586137Recruiting
Understanding Systemic Vasculitis: A Long-Term Health Study
This study follows people with systemic vasculitis (inflammation of blood vessels throughout the body) to better understand how the disease progresses and what outcomes to expect. Researchers will collect health information over time to improve treatment and care for vasculitis patients.
Pavia, PaviaAges 18 years+ - NCT07588230Recruiting
Nerve Block for Minimally Invasive Heart Valve Surgery Pain
This study tests a targeted nerve block (pain-numbing injection) to help manage pain after minimally invasive heart valve surgery. Researchers want to see if this technique reduces pain and the need for opioid medications during recovery.
Diyarbakır, Outside of the USAges 18–75 - NCT07588256Recruiting
AI Digital Health Platform for High Blood Pressure and Related Conditions
This study uses artificial intelligence and a digital health app to help manage high blood pressure, high cholesterol, diabetes, kidney disease, and heart disease. It aims to help people track their health at home and receive better care recommendations through technology.
New Taipei CityAges Any age - NCT07588295Recruiting
How immune cells respond in heart and leg blood vessel disease
This study examines how immune cells (macrophages) behave differently in patients with blocked arteries in the heart or legs. Understanding this may help doctors develop better treatments for these conditions.
Cotignola, RavennaAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,066 recruiting cardiology studies from the U.S. registry right now, out of 15,554 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.