Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,981 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2482
- Phase 4481
- Phase 3449
- Phase 1361
- Phase 1/Phase 2164
- Phase 2/Phase 387
Top conditions
- Stroke841
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke201
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke138
- Myocardial Infarction100
- Pulmonary Hypertension100
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas117
Recruiting studies9,978 total
- NCT07581899Recruiting
Heart Health Program for Lumbee Indian Women
This study tests a mind-body program designed to reduce heart disease risk in Lumbee Indian women. The program combines stress-management techniques with lifestyle changes to help improve heart health.
Pembroke, North CarolinaAges 18–55 - NCT07537868RecruitingPhase 2
Montelukast to reduce heart damage after heart attack
This study tests whether montelukast (a medication that reduces inflammation) can limit heart damage when given immediately after a sudden heart attack. Researchers will measure inflammation markers and heart injury to see if this drug helps patients recover better.
Al MansurahAges 30–75 - NCT07532733Recruiting
Sedation Safety During Minimally Invasive Heart Valve Procedure
This study examines how a specific sedative medication (dexmedetomidine) affects breathing and heart function during a minimally invasive procedure to replace a faulty heart valve. Researchers want to ensure the sedation is safe and effective for older adults.
BrusselsAges 60 years+ - NCT07484477Recruiting
Sitting less to improve heart and lung function after heart surgery
This study tests whether helping people sit less and move more after heart surgery can improve their breathing, heart function, and quality of life. If you're between 50 and 80 and have had heart surgery, this may help you recover better.
Peshawar, KPKAges 50–80 - NCT07481578Recruiting
Exercise and gut health study for active men
This study looks at how your training load affects your gut bacteria and how that relates to exercise performance and muscle health. It may help understand overreaching in healthy men.
Leuven, Vlaams BrabantAges 18–45 - NCT07496424Recruiting
Comparing manual vs automatic strain in heart surgery patients
This trial compares two ways of measuring heart strain (the heart's ability to squeeze) after cardiac surgery. It uses GE ultrasound machines and special software to see if automatic measurements are as good as manual ones.
ViennaAges 18–99 - NCT07501923Recruiting
How heat exposure day and night affects human health
This study looks at how exposure to heat during the day, night, or both affects the health of healthy young adults. It may help understand how heat impacts the body and find ways to protect people from heat-related risks.
Hefei, AnhuiAges 18–30 - NCT07434193Recruiting
Pacing study after aortic valve replacement
This trial tests if special pacing of the heart's lower chambers (called cardiac resynchronization therapy, or CRT) can help people who develop a new electrical delay in the heart after having a transcatheter aortic valve replacement (TAVI). The study compares two types of pacing to see which works better for recovery.
BudapestAges 18 years+ - NCT07400458Recruiting
Long-term study after Hearticellgram-AMI for heart attack patients
This study checks on people who have already received a treatment called Hearticellgram-AMI for heart attack. It wants to see how they are doing over the long term.
Seoul, GangnamAges Any age - NCT07435337RecruitingPhase 4
Pain medicine study for heart surgery patients
This trial tests two different pain medicines, nalbuphine and fentanyl, to see which one causes fewer changes in blood pressure and heart rate during the placement of a breathing tube for heart surgery.
Rawalpindi, Punjab ProvinceAges 40–60 - NCT07432607Recruiting
High-Flow Nasal Oxygen vs Face Mask for Heart Surgery
This trial compares two ways of giving oxygen during a heart surgery that uses small chest cuts. One method is a face mask, the other is a high-flow nasal tube. The study will see which keeps your oxygen levels better while you are awake but relaxed.
Istanbul, KARTALAges 18–75 - NCT07385170Recruiting
Glucose monitor accuracy during heart surgery
This trial checks how well a continuous glucose monitor works during heart surgery. It aims to help manage blood sugar levels more safely in the operating room.
SeoulAges 19 years+ - NCT07386379Recruiting
Propofol infusion for nausea after heart bypass surgery
This study tests whether a continuous infusion of propofol (a common anesthesia medicine) during and after heart bypass surgery can reduce postoperative nausea and vomiting. If you are having planned bypass surgery and meet basic health criteria, this trial may help find a better way to feel more comfortable after your operation.
Istanbul, Outside of the USAges 18 years+ - NCT07385599Recruiting
Study of a new heart device for atrial fibrillation patients
This trial tests a new device called LAmbre™ II that closes off a part of the heart called the left atrial appendage to help prevent strokes in people with atrial fibrillation who cannot take blood thinners.
ShatinAges 18 years+ - NCT07331558Recruiting
Virtual reality rehab for heart surgery recovery
This study tests if virtual reality exercises can improve your heart and lung fitness after coronary artery bypass surgery. If you still feel short of breath, this might help you recover better.
Lahore, Punjab ProvinceAges 30–60 - NCT07348510Recruiting
Diuretic Effect of Aminophylline and Furosemide in Heart Surgery Patients
This study is testing if a combination of two medicines (aminophylline and furosemide) can help the kidneys produce more urine after heart surgery. It may help reduce fluid buildup and protect kidney function.
CairoAges 18–65 - NCT07303855Recruiting
Better fluid management after major abdominal surgery
This study compares two ways of giving fluids to people after major abdominal surgery in the ICU. It will see if using a measure of how much blood the heart pumps (cardiac index) is better than the usual method based on vein pressure.
Jakarta Pusat, DKI JakartaAges 18–65 - NCT07327840RecruitingPhase 2
Study of Kylo-11 for heart disease with high Lp(a)
This trial tests a new drug, Kylo-11, for people with heart or blood vessel disease and high Lp(a), a type of cholesterol that raises risk of heart problems. The study will see if Kylo-11 can help lower that risk.
Los Angeles, CaliforniaAges 18–80 - NCT07316231Recruiting
AI ECG accuracy for atrial fibrillation and tachycardia
This study tests an artificial intelligence (AI) system that reads 12-lead ECGs (a standard heart test) to see how accurately it can detect atrial fibrillation or atrial tachycardia. You may be able to join if you have these heart rhythm issues and can have a normal rhythm at the time of the test.
Ōta-ku, TokyoAges 18–99 - NCT07304115Recruiting
Noise from mechanical heart valve and quality of life
This study looks at how the noise from a mechanical heart valve affects your quality of life after surgery. You will be asked about your memories of the information you received before surgery and how you feel now.
ParisAges 18 years+ - NCT07305922Recruiting
Treating delayed brain damage after a brain bleed
This study tests a treatment for people who have had a brain bleed (subarachnoid hemorrhage) and are at risk for delayed brain damage due to narrowed blood vessels. It looks at whether a special procedure to relax the vessels (spasmolysis) combined with raising blood pressure can prevent long-term harm.
StockholmAges 18 years+ - NCT07324902Recruiting
How Lp(a) affects heart and blood vessel health
This study looks at how a fatty substance in your blood called lipoprotein(a), or Lp(a), might affect the stiffness of your arteries and how well your heart muscle works. It will help us understand if high Lp(a) is connected to early signs of heart disease.
Athens, AtticaAges 18–75 - NCT07251361Enrolling by invitation
Exercise program for heart failure with preserved ejection fraction
This study tests whether a special exercise program that combines different types of training (like aerobic, strength, and balance) can improve heart and muscle function, daily abilities, and quality of life in people with heart failure with preserved ejection fraction (HFpEF). You may benefit if your heart failure is stable and you are able to exercise safely.
Pamplona, NavarreAges 18 years+ - NCT07255469Recruiting
Fluid response test in children after heart surgery
This trial tests how well the body responds to a fluid bolus in children who have just had heart surgery. It uses blood gas tests and maybe an ultrasound to guide treatment.
Bron, FranceAges birth–15 years
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,981 recruiting cardiology studies from the U.S. registry right now, out of 15,236 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.