Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT05685069Recruiting
Studying stroke risk factors in people with silent brain infarcts
This study looks for what may have caused “silent” mini-strokes in the brain that were found on MRI, and which risk factors might be changeable. It may help doctors better understand how to prevent future stroke in people who have no clear stroke symptoms from the finding.
ToursAges 16 years+ - NCT04255563Recruiting
Drug-coated balloon for coronary artery disease
This trial studies a balloon treatment coated with medicine (to help keep the artery open) for people with coronary artery disease. You may be a candidate if you are planned to receive this type of procedure and do not have certain key safety risks.
Nanjing, JiangsuAges 18 years+ - NCT07643818Enrolling by invitationPhase 2
Intravenous iron for heart failure patients with low iron
This study tests whether giving intravenous iron improves symptoms, quality of life, and exercise ability in people with heart failure and low iron levels. Participants will receive iron infusions and be monitored over time to see if their condition improves.
Saint HelierAges 18 years+ - NCT07640542RecruitingEarly Phase 1
Brain imaging study for Parkinson's and MSA patients
This early-stage research trial tests a new brain-imaging tracer called [11C]MODAG-005 to help doctors better understand Parkinson's disease (PD) and multiple system atrophy (MSA). You would undergo PET/CT and MRI scans twice, a few weeks apart, to see how reliable the imaging is.
Tübingen, Baden-WurttembergAges 50–75 - NCT07642362Recruiting
Digital Support to Improve Quality of Life in Multiple Myeloma
This trial tests a digital app designed to help people with multiple myeloma (a blood cancer) manage their quality of life and symptoms. The study wants to see if using this app on a phone or computer can help patients feel better and stay connected to their care.
AthensAges Any age - NCT07644364RecruitingPhase 1
Blood Pressure Medication Study for Japanese Adults
This early-stage trial tests a new blood pressure medication called HJB647 in Japanese adults with elevated or high blood pressure. The study aims to see if the drug is safe and how the body handles it.
Sumida Ku, TokyoAges 18–60 - NCT05439863Recruiting
Valve procedure trial for severe aortic valve problems
This trial studies people with severe aortic valve disease who will receive a catheter-based valve replacement (TAVR). It aims to check how well this approach works for fixing a narrowed or leaky aortic valve, and to monitor outcomes afterward.
Nanjing, JiangsuAges 18 years+ - NCT05800002Recruiting
IVUS-guided stent placement for badly calcified heart arteries
This trial studies a heart procedure that uses a special camera to guide where to place a drug-coated stent in an artery with heavy calcium. It may help improve how well the stent fits and works for people with certain types of coronary artery blockages.
Nanjing, JiangsuAges 18 years+ - NCT06691230Recruiting
Looking at blood flow after stroke clot removal
This study uses a special CT scan to see how well blood flows in the brain after a stroke patient has had a procedure to remove a clot. The goal is to learn more about recovery and improve future care.
BaselAges 18 years+ - NCT07638995Recruiting
Leadless Pacemaker for Slow Heart Rhythm
This trial tests a new type of pacemaker (without traditional wires) for people whose hearts beat too slowly. It may help you if you have symptoms like fainting or fatigue from a slow heartbeat and haven't had a pacemaker before.
Bay Shore, New YorkAges 18 years+ - NCT07640828Recruiting
Digital Models to Improve Aortic Stent Graft Outcomes
This study uses computer models and artificial intelligence to better understand how aortic stent grafts (TEVAR) work in patients. Researchers will analyze your medical imaging to create a digital copy of your aorta, which may help doctors predict long-term success and improve future patient care.
MilanAges 18 years+ - NCT07641309Recruiting
Health Program for Diabetes, Lung, or Heart Disease
This study measures how a health improvement program helps people with type 2 diabetes, chronic lung disease, or heart disease. Researchers will track your health before and after you participate in the program offered by your local municipality.
FrederiksværkAges 18 years+ - NCT07638683RecruitingPhase 2
Teclistamab and Daratumumab for New Multiple Myeloma With Amyloidosis
This trial tests a combination of two newer cancer-fighting drugs (teclistamab and daratumumab) to treat people who have just been diagnosed with multiple myeloma—a blood cancer—and also have light chain amyloidosis, a condition where abnormal proteins build up in organs. The goal is to see if this combination works better and is safe for newly diagnosed patients.
ShanghaiAges 18 years+ - NCT07642765Recruiting
Frailty Score and Blood Pressure Changes During Surgery
This study looks at a simple scoring system (EASIX) that predicts whether older or frail patients will experience dangerous blood pressure drops when anesthesia is given before surgery. Understanding this risk might help doctors better protect vulnerable patients during their operations.
KonyaAges 18 years+ - NCT07645066Recruiting
Heart Pacemaker Placement to Prevent Irregular Heartbeat
This trial tests a new pacemaker placement technique for people with a slow heartbeat (sinus node dysfunction) who need a pacemaker anyway. The goal is to see if this special placement can help prevent atrial fibrillation, a type of irregular heartbeat that can cause stroke and other complications.
Anqing, AnhuiAges 18 years+ - NCT07638137Recruiting
Advanced Heart Catheter Testing for Stent Patients With Chest Pain
This study tests a detailed diagnostic procedure during heart catheterization for patients who previously had stents placed and now have chest pain or signs of heart stress. The goal is to better understand blood flow in treated arteries to guide treatment decisions.
Leganés, MadridAges 18 years+ - NCT07638462Recruiting
Early mobility recovery program after acute stroke
This study tests whether early movement and physical activity help stroke patients recover better mobility. You'd be in the hospital after a recent stroke, and the team would work with you on safe movement and exercises during your recovery.
Winston-Salem, North CarolinaAges 18 years+ - NCT07639606Recruiting
Mobile therapy app for mood after recent stroke
This study tests whether using a smartphone or tablet app for cognitive behavioral therapy (a type of talk therapy you do on your device) can help with anxiety and depression in the first month after a stroke. The goal is to see if this convenient, at-home approach improves how you feel during early recovery.
New York, New YorkAges 18–79 - NCT07643337Recruiting
Vagus Nerve Stimulation With Rehab to Improve Walking After Stroke
This study tests whether vagus nerve stimulation (a small device that stimulates a nerve in your neck) combined with rehabilitation therapy can help improve walking and leg function in stroke survivors. You would be one of the first to try this combination approach for stroke recovery.
Buffalo, New YorkAges 22–80 - NCT07642154Recruiting
Balance and Sensory Training After Stroke
This study compares two types of physical therapy to help stroke patients improve balance, sensation in their legs, and confidence walking. The goal is to see which approach works better for people recovering from stroke.
Lahore, Punjab ProvinceAges 50–65 - NCT07643610Recruiting
Heart Failure Crisis Registry Study
This registry collects information from patients admitted to the hospital with cardiogenic shock—a serious condition where the heart cannot pump enough blood to the body. Doctors will gather data to better understand what happens to these patients and how to improve their care.
Basel, Canton of Basel-CityAges 18 years+ - NCT07641790Recruiting
Vibration Devices to Improve Arm Movement After Stroke
This study tests whether wearing small vibrating devices on your arm can help improve movement and function in the arm weakened by stroke. The vibrations may help retrain your brain and muscles to work together better during the recovery period.
Faisalābad, Punjab ProvinceAges 30–60 - NCT07641582Recruiting
Gene Testing to Predict Heart Rhythm Problems
This study uses a genetic test to identify who might develop atrial fibrillation (an irregular heartbeat) in the future. Researchers believe certain genetic patterns combined with health factors can help predict this condition early, which could lead to better prevention.
IncheonAges 20–79 - NCT07644715Recruiting
AI Analysis of Heart Rhythms and Immune-Related Heart Damage
This study uses artificial intelligence to analyze heart electrical recordings (ECGs) from existing patient databases to better detect dangerous heart rhythm problems and heart inflammation caused by cancer immunotherapy. Researchers are not giving any new treatments—they're studying existing data to improve diagnosis.
ParisAges Any age
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.