Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,981 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2482
- Phase 4481
- Phase 3449
- Phase 1361
- Phase 1/Phase 2164
- Phase 2/Phase 387
Top conditions
- Stroke841
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke201
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke138
- Myocardial Infarction100
- Pulmonary Hypertension100
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas117
Recruiting studies9,978 total
- NCT06648577Recruiting
3D ultrasound heart muscle wave measurements
This study uses 3D ultrasound to measure mechanical waves in the heart muscle of people with different severities of mitral regurgitation (a leaky heart valve). It aims to better understand how the heart adapts to the leak, which could help guide treatment decisions.
Paris, ParisAges 18 years+ - NCT07052123Recruiting
Blood pressure monitoring in ICU with DARE device
This trial tests a new non-invasive device (DARE) to measure blood pressure and core body temperature in patients who are already receiving standard monitoring with an arterial line and a urinary catheter in the ICU.
Saint-Denis, FranceAges 18 years+ - NCT07417462Recruiting
Pain relief after heart surgery to help you recover faster
This trial tests a combination of pain medicines given during cardiac surgery to reduce pain and speed up recovery. It may help patients who are having a first-time bypass surgery through a standard breastbone incision.
AsyutAges 40–60 - NCT07053657Recruiting
Vitamin D for heart health in overweight teens
This study looks at whether giving vitamin D can improve heart and metabolic health in overweight or obese teens who have low vitamin D levels. It may help lower risks like high blood sugar or cholesterol.
Anqing, AnhuiAges 10–16 - NCT05275088Recruiting
Transcatheter valve replacement for badly calcified heart valves
This trial tests Prizvalve, a catheter-based procedure to replace a severely damaged “atrioventricular” valve in people at high risk from open-heart surgery. It may help reduce symptoms caused by valve narrowing or leaking when traditional surgery is not a good option.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06094816RecruitingPhase 4
Brain MRI study on salt and blood pressure
This study uses MRI scans to look at how the brain controls salt and blood pressure. It is for people aged 40–60 with normal to slightly high blood pressure, who have no major health conditions.
Newark, DelawareAges 40–60 - NCT07699016Recruiting
Hemostatic agent use in heart and blood vessel surgery
This trial surveys surgeons about how they use hemostatic agents (medications that stop bleeding during surgery). It aims to understand current practices and improve patient safety.
Milan, MIAges 18 years+ - NCT07695376Recruiting
Caramel study on women's health with digital devices
This study follows women aged 40–60 to see how smartphones and wearable devices can help monitor health over time. It aims to improve care by using technology that fits easily into daily life.
BogotáAges 40–60 - NCT07712445Recruiting
Testing a clot-busting drug coated with platelet membranes
This study tests a new way to deliver a clot-dissolving drug called tenecteplase. The drug is coated with platelet membranes to target blood clots in arteries. It may offer a safer, more effective treatment for heart attack patients and is also enrolling healthy volunteers for comparison.
Nanjing, JiangsuAges 18–75 - NCT07687745RecruitingEarly Phase 1
Breathing exercises for healthy blood pressure during pregnancy
This trial tests whether a simple breathing exercise device can help keep your blood pressure healthy during pregnancy. You will use a small device 5-7 days a week and sync measurements with your smartphone.
Tucson, ArizonaAges 18–55 - NCT07621120Recruiting
Wearable Device to Predict Surgery Risk in Older Adults
This study uses a wristwatch-like device to measure your movement and body functions before and after surgery to help predict which older patients might have complications. The goal is to improve safety planning for people 65 and older having surgery.
Beijing, Beijing MunicipalityAges 65 years+ - NCT07623785Recruiting
Beef and Brain Health in Older Adults
This study looks at whether eating lean beef and dairy products daily affects brain health markers in people 65 and older. Researchers will track blood, urine, and other samples to see if beef consumption influences how your brain functions at the molecular level.
Brookings, South DakotaAges 65 years+ - NCT07658989Recruiting
Blood thinners in pregnancy with mechanical heart valves
This study looks at the best way to manage blood thinners for pregnant people who have mechanical heart valves. It aims to find the safest approach for both the mother and the baby.
Toronto, OntarioAges 18–45 - NCT07611890RecruitingPhase 4
Comparing two medications to reduce heart stress during cardiac surgery
This trial tests whether dexmedetomidine or lignocaine better prevents dangerous heart-rate and blood-pressure changes when a breathing tube is placed during heart surgery. If you're having cardiac surgery and are at high risk for heart complications, this study may help protect your heart during the procedure.
Rawalpindi, Punjab ProvinceAges 18–65 - NCT07677319Recruiting
Heart surgery after age 75: a study on recovery
This study looks at how well people aged 75 and older recover after emergency heart surgery. It uses a special test to measure frailty and quality of life for one year after surgery.
Bordeaux, FranceAges 75 years+ - NCT07628296Recruiting
Blood Pressure Measurement Accuracy Study
This study tests how accurately a non-invasive blood pressure device measures your pressure compared to a direct measurement from an arterial line (a thin tube in an artery that directly measures pressure). You'll need to be in a hospital or intensive care setting where you already have an arterial line as part of your standard care.
TampereAges 18 years+ - NCT07628270Recruiting
Heart Surgery Outcomes Study Using CT Scans and Blood Tests
This study follows patients who had heart bypass surgery guided by special CT scans and blood flow measurements. Researchers want to understand how well the surgery works and study a blood protein called Lp(a) that may affect heart health.
Milan, MIAges 18 years+ - NCT07574736Recruiting
Finding the right way to place a heart ultrasound probe
This study helps doctors find the easiest way to correctly position a small ultrasound probe in your food pipe to get better pictures of your heart. If you're in the ICU and need this type of heart imaging, this research could improve how safely and quickly the procedure is done.
Merano, BZAges Any age - NCT07556627Recruiting
How chocolate affects heart health during long sitting
This study tests whether eating chocolate before sitting for several hours helps protect your heart and blood vessels. Researchers want to see if chocolate's natural compounds can reduce the harmful effects of prolonged sitting on cardiovascular health.
Riyadh, Riyadh RegionAges 18–40 - NCT07564531Recruiting
Safe sedation for heart catheterization in children
This study tests whether a combination of two sedative medications (dexmedetomidine and ketamine) works safely and effectively to keep children calm and still during heart catheterization—a procedure where a thin tube is guided through blood vessels to the heart for diagnosis or treatment.
HanoiAges Up to 18 years - NCT07533214Enrolling by invitation
Left-Handed Endoscopic Mitral Surgery Training Program
This trial tests a specialized training program designed specifically for left-handed surgeons learning minimally invasive heart valve surgery. The goal is to help left-handed surgeons develop the precise hand skills needed to perform these delicate procedures using specially adapted equipment and techniques.
PortugalAges Any age - NCT07584187Recruiting
Brain monitoring during emergency heart-lung support treatment
This study uses special monitoring devices to measure brain activity in patients receiving emergency mechanical heart-lung support (ECMO). The goal is to help doctors quickly predict which patients might recover neurologically and guide early treatment decisions.
ViennaAges 18 years+ - NCT07546656Recruiting
Using Vein Size to Predict Fluid Response in ICU Patients
This study tests whether measuring the size of a vein in your groin using ultrasound can help doctors decide if you need more fluids when you're critically ill in the ICU. The goal is to improve how doctors manage fluid treatment for patients on breathing machines.
Istanbul, IstanbulAges 18 years+ - NCT07577596RecruitingPhase 4
Continuous Furosemide Infusion for Heart Failure Fluid Overload
This study tests whether giving furosemide (a water pill) as a continuous IV drip works better than standard doses for patients hospitalized with heart failure and fluid buildup. The goal is to help your body get rid of excess fluid more effectively.
RandersAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,981 recruiting cardiology studies from the U.S. registry right now, out of 15,236 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Immune system & allergy
- Women’s health & pregnancy
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- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.