Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT07629791Recruiting
Augmented reality and brain stimulation for balance problems
This study tests whether combining augmented reality (a computer-based visual experience) with a non-invasive brain stimulation technique called tDCS can help improve balance and walking in people with balance impairment. You would receive therapy sessions using both technologies together.
Rawalpindi, Punjab ProvinceAges 18–90 - NCT07636759Recruiting
AI Heart Rhythm Test for Heart Pump Weakness
This study tests whether an artificial intelligence system can detect a weakened heart pump using an ECG (heart rhythm test). If successful, it could help doctors diagnose heart problems faster and more easily.
Suwon, Gyeonggi-doAges 19 years+ - NCT07630402Recruiting
Heart Imaging Study for Women With Early Breast Cancer
This study helps doctors find the best way to monitor heart health in women with HER2-positive breast cancer who are receiving a type of targeted chemotherapy. The goal is to catch any heart problems early and keep you safe during treatment.
Rochester, New YorkAges 18–79 - NCT07629856Recruiting
Dual-Task Training to Improve Balance After Stroke
This study tests whether doing balance exercises while performing mental tasks together can help stroke survivors improve their stability and walking ability. Many stroke patients struggle with balance, and this training aims to help them regain confidence and reduce fall risk.
Chak One Hundred Fifty-seven, Punjab ProvinceAges 40–75 - NCT07636343Recruiting
Eccentric Training for Heart Failure Recovery
This trial tests a special type of strength training (eccentric exercise, where muscles lengthen under load) for people with heart failure who have reduced pumping ability. The goal is to improve your exercise capacity and heart function safely.
EdegemAges Any age - NCT07631156RecruitingPhase 4
Safely Reducing Heart Failure Medications After Recovery
This study tests whether patients whose heart function has fully recovered after surgery or a heart procedure can safely reduce or stop their heart failure medications. Researchers will carefully monitor whether gradually lowering these medicines is safe and maintains heart health.
Daegu, DaeguAges 19 years+ - NCT07633145Recruiting
Lifestyle Changes to Lower Blood Pressure in Kidney Disease
This study tests whether lifestyle changes—like diet and exercise—can help lower blood pressure in Black adults with moderate kidney disease. It's designed specifically for people at higher risk of kidney problems, and the goal is to see if these changes can slow kidney disease progression and reduce heart disease risk.
Durham, North CarolinaAges 18 years+ - NCT07637266Recruiting
Heart Protection Methods During Bypass Surgery
This study compares two different methods of protecting your heart during coronary artery bypass surgery. Researchers will use MRI scans to see which method keeps heart muscle healthier after surgery.
ZagrebAges 18–80 - NCT07634640RecruitingEarly Phase 1
Testing an Inflammation Treatment for Heart Failure
This early-stage trial tests a new approach to treat heart failure with preserved ejection fraction (HFpEF)—a type of heart failure where the heart's pumping strength is normal, but it doesn't relax properly. Researchers believe inflammation plays a role and want to see if targeting it can help patients feel better and function more easily.
Gainesville, FloridaAges 18–85 - NCT07629687Recruiting
Ear Nerve Stimulation for Balance After Stroke
This trial tests a non-invasive device that stimulates a nerve in your ear to help improve balance and body control after stroke. It may help you regain stability and reduce symptoms like muscle tightness.
Islamabad, Punjab ProvinceAges 18–70 - NCT07636642Recruiting
New Heart Attack Blood Test Accuracy Study
This study compares two versions of a sensitive heart attack blood test to see how well the newer version can quickly rule out heart attacks in the emergency department. You'll have blood drawn as part of your normal care, and researchers will review your medical records.
Edinburgh, MidlothianAges 18 years+ - NCT07635498Recruiting
Virtual versus in-person care after stroke
This study compares two ways of caring for stroke patients who aren't candidates for emergency clot-removal surgery. Half will receive care through a virtual stroke unit (telemedicine), and half will receive traditional in-person care at the hospital. The goal is to see if both approaches work equally well for recovery and safety.
SevilleAges 18 years+ - NCT07637084Recruiting
Light therapy for chronic pain and fatigue in Ehlers-Danlos Syndrome
This trial tests whether a non-invasive light therapy called photobiomodulation can reduce chronic pain and fatigue in people with hypermobile Ehlers-Danlos Syndrome (hEDS), a genetic condition affecting connective tissue. The light is applied to the skin and may help cells produce energy and reduce inflammation.
Boulogne-Billancourt, Île-de-France RegionAges 18 years+ - NCT07634991RecruitingPhase 4
N-acetyl Cysteine for Diabetic Eye Disease
This study tests whether a supplement called N-acetyl cysteine can help slow or improve mild to moderate diabetic eye disease (diabetic retinopathy). The goal is to see if it's safe and effective for people with type 2 diabetes.
CairoAges 18–70 - NCT06250257RecruitingPhase 3
Bromocriptine for Heart Weakness in Women 18-50
This trial tests a medicine called bromocriptine to see if it helps women with a weak heart muscle (dilated cardiomyopathy). It is for women between 18 and 50 whose heart weakness was found recently or is caused by blocked arteries, and who are not pregnant or planning pregnancy.
Jimma, OromiyaAges 18–50 - NCT05590871Recruiting
Kidney nerve ablation to treat hard-to-control blood pressure
This trial tests a procedure that targets nerves near the kidney (renal denervation) to help lower blood pressure in people whose hypertension is not controlled despite medication. It uses a special 3D mapping system to guide the procedure.
Chongqing, Chongqing MunicipalityAges 18–70 - NCT05930899Recruiting
Study tissue and blood samples from heart disease patients
This study builds a biobank, meaning it collects and stores your health information, blood, and possibly heart-related samples to help researchers learn why heart conditions happen. You might join if you have certain heart diagnoses and are having cardiac surgery for a problem other than an aortic valve issue.
Montreal, QuebecAges 19 years+ - NCT06698159Recruiting
Wider pulmonary vein isolation in AFib ablation with single-shot cryoablation
This study tests a new approach to a common procedure for atrial fibrillation (AFib) called pulmonary vein isolation. It uses a single-shot cryoablation technique to treat people with paroxysmal or persistent AFib.
Pozzilli, IserniaAges 18 years+ - NCT06564831Recruiting
Placental graft for diabetic foot ulcers
This study tests whether a special placental tissue graft placed on a diabetic foot ulcer helps it heal faster than standard wound care alone. It is for people with a diabetic foot ulcer that has not healed after 4 weeks of usual care.
Clinton Township, MichiganAges 18 years+ - NCT07623525RecruitingPhase 1/Phase 2
DIAG723 study for hereditary hemorrhagic telangiectasia
This study tests a new drug called DIAG723 in adults with hereditary hemorrhagic telangiectasia (HHT), a genetic condition that causes abnormal blood vessels and bleeding. Depending on which part of the study you qualify for, the drug may help reduce nosebleeds, improve anemia, or help with lung blood vessel problems caused by HHT.
Camperdown, New South WalesAges 18 years+ - NCT07621003Recruiting
PULSed Field Ablation for New-Onset Atrial Fibrillation
This study tests a newer ablation technique using pulsed electrical energy to treat atrial fibrillation (an irregular heartbeat). You may qualify if you were recently diagnosed with AF and haven't had ablation before.
Bad OeynhausenAges 18 years+ - NCT07621055Recruiting
AI software to guide heart rhythm ablation treatment
This study tests new AI software (Volta AF-Xplorer II) that helps doctors guide catheter ablation—a procedure to treat irregular heartbeats like atrial fibrillation. The software may help doctors perform the procedure more effectively and safely in real-world settings.
MarseilleAges 18 years+ - NCT07628829Recruiting
Video AI to Monitor Newborn Brain Health
This study uses artificial intelligence to watch and analyze videos of newborns in the hospital nursery or NICU to help doctors spot neurological problems early. The goal is to see if this video AI tool can safely and accurately help care for newborns during their hospital stay.
New York, New YorkAges Any age - NCT07628296Recruiting
Blood Pressure Measurement Accuracy Study
This study tests how accurately a non-invasive blood pressure device measures your pressure compared to a direct measurement from an arterial line (a thin tube in an artery that directly measures pressure). You'll need to be in a hospital or intensive care setting where you already have an arterial line as part of your standard care.
TampereAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.