Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,982 recruiting studies in this area right now.
By phase
- Not applicable7,962
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke844
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California465
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas118
Recruiting studies9,979 total
- NCT07688551RecruitingPhase 2/Phase 3
Speech therapy with brain stimulation for aphasia after stroke
This trial tests if adding a gentle brain stimulation (tDCS) to speech therapy helps people with aphasia (trouble speaking) after a stroke. If you had a stroke more than 6 months ago and have trouble naming objects, this study may be a good fit.
Charleston, South CarolinaAges 25–80 - NCT07172971RecruitingPhase 1
SGLT2i drug for heart health in Duchenne muscular dystrophy
This trial tests if an SGLT2i medication can help protect heart function in people with Duchenne muscular dystrophy (DMD). The drug is already approved for other conditions, and researchers want to see if it can slow or prevent heart muscle damage.
Nashville, TennesseeAges 8–18 - NCT07388355Recruiting
Ease of use study for a new heart monitor device
This study tests how easy it is to use a new device that records your heart's electrical activity through a simple patch on your chest. You will need to use a smartphone app with the patch.
New London, North CarolinaAges 18 years+ - NCT05396105Enrolling by invitationPhase 2/Phase 3
Oral PHA-022121 extension for hereditary angioedema attacks
This study is an extension trial of an oral medicine (PHA-022121) for treating acute attacks in people with hereditary angioedema (HAE), especially HAE type III (HAE-nC1INH). It checks whether continuing this oral treatment can safely help manage attacks after you’ve taken it before.
Birmingham, AlabamaAges 12 years+ - NCT06096675Recruiting
Physical activity study for cardiac amyloidosis patients
This study tests whether a 12-week supervised exercise program is safe and helpful for people with cardiac amyloidosis and heart failure. It aims to see if regular exercise can improve how you feel and function.
Charlotte, North CarolinaAges 18 years+ - NCT07715656Recruiting
Middle-meningeal-artery embolization for chronic subdural hematoma
This trial studies a procedure called middle-meningeal-artery embolization, which blocks the blood supply to a chronic subdural hematoma (a slow-growing blood collection around the brain). It compares outcomes in people with one-sided versus both-sided bleeds, and aims to see if this less invasive treatment can help reduce the need for surgery or improve recovery.
Burlington, MassachusettsAges 18 years+ - NCT07715630RecruitingPhase 1
PICX CAR-T therapy for relapsed or hard-to-treat multiple myeloma
This trial tests a new treatment called PICX CAR-T, a type of immune cell therapy, for multiple myeloma that has come back or not responded well to at least two prior treatments. It aims to see if this therapy can help control the disease.
Kunming, YunnanAges 18 years+ - NCT07714746RecruitingPhase 3
Ivabradine for treating cardiogenic shock after heart attack
This trial tests if ivabradine, a drug that lowers heart rate, can help patients in cardiogenic shock after a type of heart attack called STEMI. It is for patients with a fast heart rate (at least 100 beats per minute) who cannot take beta-blockers.
KarachiAges 18–75 - NCT07713615Recruiting
Blood clots and heart ultrasound in people with device-detected afib
This study looks at blood clotting markers and heart ultrasound in people who have a pacemaker or defibrillator that has detected short episodes of atrial fibrillation (afib). The goal is to better understand stroke risk and help guide future treatment decisions.
EsbjergAges 50 years+ - NCT07501299Recruiting
HeartBeam ECG Registry for heart monitoring
This registry collects ECG data from people who are already getting an ECG for their heart health. It uses a device called HeartBeam to see if it works as well as the standard ECG machine.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07713537Recruiting
Stroke risk score for AF patients on blood thinners
This study is testing a new scoring system to predict stroke risk in people with atrial fibrillation who are taking DOAC blood thinners. The goal is to help doctors personalize treatment and prevent blood clots.
Barcelona, BarcelonaAges Any age - NCT07629687Recruiting
Ear Nerve Stimulation for Balance After Stroke
This trial tests a non-invasive device that stimulates a nerve in your ear to help improve balance and body control after stroke. It may help you regain stability and reduce symptoms like muscle tightness.
Islamabad, Punjab ProvinceAges 18–70 - NCT07436689Enrolling by invitationPhase 3
Long-term study of oral levosimendan for heart failure
This long-term study gives continued access to the oral levosimendan medication for people who finished the earlier TNX-103 study. The goal is to see if ongoing treatment remains safe and helpful.
Chicago, IllinoisAges Any age - NCT05890716Recruiting
AI analyzes your ECG to help in high-risk heart rhythm cases
This trial uses an AI program to review ECG heart-tracing data collected from short-term monitoring devices. It aims to see whether the AI can better detect concerning heart rhythm patterns in people who are high risk for heart rhythm or heart problems.
Groningen, Provincie GroningenAges 4 years+ - NCT07629791Recruiting
Augmented reality and brain stimulation for balance problems
This study tests whether combining augmented reality (a computer-based visual experience) with a non-invasive brain stimulation technique called tDCS can help improve balance and walking in people with balance impairment. You would receive therapy sessions using both technologies together.
Rawalpindi, Punjab ProvinceAges 18–90 - NCT07629856Recruiting
Dual-Task Training to Improve Balance After Stroke
This study tests whether doing balance exercises while performing mental tasks together can help stroke survivors improve their stability and walking ability. Many stroke patients struggle with balance, and this training aims to help them regain confidence and reduce fall risk.
Chak One Hundred Fifty-seven, Punjab ProvinceAges 40–75 - NCT07113223Recruiting
AI heart test for heart failure detection in people over 65
This trial uses an artificial intelligence system to analyze electrocardiograms (ECGs, which are recordings of your heart's electrical activity) to detect heart failure early. It is for people over 65 who either have symptoms that might be heart failure or have risk factors for heart failure but no current symptoms.
MadridAges 65 years+ - NCT07405762Recruiting
Stroke recovery after blood clot removal: brain blood flow study
This trial looks at how blood flow and brain activity change in the first days after a stroke caused by a large blockage in the front part of the brain. It tests if certain patterns can help predict recovery after a procedure to remove the clot.
Xi'an, Shan'xiAges 18–85 - NCT06361537RecruitingPhase 3
Study of a C1 inhibitor medicine for HAE attacks
This trial tests a plasma-derived C1 esterase inhibitor to treat and prevent acute attacks in people with hereditary angioedema (HAE) types 1 or 2. It aims to see if the medicine can quickly relieve swelling episodes and reduce their frequency.
Centennial, ColoradoAges 2 years+ - NCT07185204Recruiting
Early detection and treatment of postpartum preeclampsia in Nepal
This study tests a new way to find and treat women at high risk for preeclampsia after childbirth. It uses a blood test and a medicine called nifedipine to prevent serious complications.
Milwaukee, WisconsinAges 18 years+ - NCT07398508RecruitingPhase 1/Phase 2
Northera for dizziness and diarrhea in Menkes disease survivors
This trial tests if the drug Northera (droxidopa) can help children with Menkes disease who have dizziness when standing or chronic diarrhea. It aims to improve these symptoms by supporting blood pressure and bowel function.
New York, New YorkAges 7–17 - NCT05701280Recruiting
Deep brain stimulation plus rehab after stroke
This trial looks at whether adding deep brain stimulation (a surgically placed device that delivers therapy signals) to rehab can improve arm function after a stroke. It is aimed at people whose stroke happened 12 months to 6 years ago and who still have arm weakness or poor control.
Phoenix, ArizonaAges 21 years+ - NCT04163614Recruiting
Testing blood pressure patterns and fluid removal during dialysis
This study looks at how blood pressure changes during hemodialysis and how much fluid is removed, to see what approach works best for controlling blood pressure. It may help dialysis patients whose blood pressure is often high before or after treatment.
Dallas, TexasAges 18 years+ - NCT07149142Recruiting
AI eye screening for children with type 1 diabetes
This study tests if an artificial intelligence (AI) system can effectively screen for eye problems related to diabetes (retinopathy) in children. The goal is to find a faster, easier way to protect your child's vision.
Prague, Prague 5Ages 11–19
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,982 recruiting cardiology studies from the U.S. registry right now, out of 15,268 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.