Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT06199180Recruiting
Comparing two ablation methods for repeat atrial fibrillation treatment
This trial tests a newer type of energy (pulsed field ablation) against the standard heat-based method (radiofrequency) for people who have already had one ablation and now have atrial fibrillation again. The goal is to see which works better for keeping your heart in a normal rhythm.
GroningenAges 18–80 - NCT06474884Recruiting
Single blood thinner after shielded stent for brain aneurysm
This study is testing whether using only one blood-thinning medication (single antiplatelet therapy) after placing a special stent (Pipeline Flex with Shield) is safe and effective for treating unruptured brain aneurysms. It is for people who have already been on two blood thinners for a few days before the stent placement.
BeijingAges 18–80 - NCT06721234Recruiting
Vein thickness and inflammation in Behcet disease
This study looks at how the thickness of the femoral vein wall and certain markers of inflammation relate to Behcet disease. It may help doctors better understand and monitor the condition.
SohagAges 19–80 - NCT07575867Recruiting
Reduced Blood Thinner Strategy After Heart Device Closure
This trial tests whether patients who receive a special device to close a hole in the heart (to prevent stroke from irregular heartbeat) can safely take fewer blood-thinning medications afterward. The study compares taking a standard blood thinner for 3 months versus taking aspirin only, to see which approach works best with fewer bleeding risks.
MoscowAges 18 years+ - NCT07575269Recruiting
New ablation treatment for irregular heartbeat
This trial tests a new tool called FARAFLEX that uses pulsed electrical energy to treat atrial fibrillation (an irregular heart rhythm). The goal is to see if this method can safely stop AF symptoms in people whose medications haven't worked.
Jonesboro, ArkansasAges 18 years+ - NCT07570264Recruiting
LEXURE device training for stroke-related speech problems
This study tests whether a device or workbook-based training called LEXURE can help people who lost the ability to speak or understand words after a stroke. If you had a stroke at least 3 months ago and struggle with language, this trial may help you regain some communication skills.
Ansan, Gyeonggi-doAges 19 years+ - NCT07575984RecruitingPhase 4
Mexidol Safety and Efficacy for Acute Ischemic Stroke
This trial tests whether Mexidol, a medication that may protect brain tissue, can help people recover better after an acute ischemic stroke (a type of stroke caused by a blood clot). The study includes stroke patients and healthy volunteers to understand how the drug works and if it's safe.
ArkhangelskAges 18–90 - NCT03356392Recruiting
Registry for stroke patients getting clot-busting treatment
This study records information from adults with an acute ischemic stroke (a stroke caused by a blocked artery) who receive clot-busting medicine within 4.5 hours. It may help doctors better understand which patients benefit from treatment and how care decisions are made for certain blocked brain arteries.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT04145024Recruiting
Pulmonary hypertension registry and blood sample biobank
This study keeps a health registry and biobank for people diagnosed with pulmonary hypertension using a specific heart test. It helps researchers better understand the condition and may improve future care.
GiessenAges Any age - NCT05053607Recruiting
Text and Fitbit monitoring during isatuximab treatment
This trial follows people with multiple myeloma who are getting isatuximab through a vein (IV). It tests how well real-world health tracking (text/app messages and Fitbit data) works during treatment, and whether it can help care teams understand your experience.
Houston, TexasAges 18 years+ - NCT05024981Recruiting
Video-based feedback and walking rehab after stroke
This trial tests whether using video feedback during walking therapy can help people regain safer walking after a recent stroke. You may be asked to walk while being video-recorded so therapists can guide your practice.
Nice, Alpes-MaritimeAges 70 years+ - NCT07576166Recruiting
Breathing and Balance Training After Stroke
This study tests whether combining rhythmic breathing exercises with balance training can improve balance and trunk control in people recovering from stroke. You'll participate in structured exercises designed to help you regain stability and core strength.
Sargodha, Punjab ProvinceAges 45–65 - NCT07576894Recruiting
How the Heart Responds to Exercise in COPD Patients
This study looks at how the right side of your heart responds when you exercise, in people with COPD (a chronic lung condition). The goal is to understand this response better and potentially improve treatments.
Aurora, ColoradoAges 40 years+ - NCT07572721Enrolling by invitation
Virtual Fitness and Health Program for Heart Health
This study tests a virtual fitness program delivered through Peloton and wearable fitness trackers to help adults improve their heart health and fitness. You'll exercise from home, track your progress with a device you already own, and provide blood samples to measure your health improvements.
San Francisco, CaliforniaAges 30–60 - NCT07569458Recruiting
Online therapy for heart disease patients with depression or anxiety
This trial tests an online program designed to help people with heart disease who are also experiencing depression or anxiety. The program is personalized to your needs and delivered through a computer or tablet over several weeks.
AalborgAges 18 years+ - NCT07576465Recruiting
Combining Movement Therapy and Electrical Stimulation After Stroke
This trial tests whether combining a specialized movement therapy (SBMT) with electrical nerve stimulation (NMES) can help improve upper arm and hand function in people recovering from stroke. The study focuses on patients 3–6 months after their stroke, when recovery potential is still strong.
Jhang, Punjab ProvinceAges 4.2 years–5.4 years - NCT07568795Recruiting
Testing a portable electronic stethoscope for heart valve disease
This study validates a new portable electronic stethoscope that can help detect heart valve disease. If you've had an echocardiogram (heart ultrasound) recently, researchers want to test whether this device accurately identifies valve problems.
Hong Kong, Pok Fu Lam Rd.Ages 18 years+ - NCT07577206RecruitingEarly Phase 1
New PET Scan Tracer for Advanced Solid Cancers
This early-stage trial tests a new radioactive tracer called [68Ga]Ga-R54 that helps doctors see certain advanced cancers (like breast, lung, colon, ovary, pancreas, or multiple myeloma) on PET scans. The tracer targets a specific protein (CXCR4) found on cancer cells, which may help doctors better detect and understand your cancer.
Naples, ItaliaAges 18 years+ - NCT07572435Recruiting
Remote Heart Exercise Program for Kids With Heart Surgery
This study tests whether kids aged 8–18 who had complex heart surgery can safely improve their fitness and well-being using exercise activities at home through a mobile app or video. The goal is to help them become more active after surgery.
SeoulAges 8–18 - NCT07574151Recruiting
Clarity of study info for aortic disease
This study is testing how clear and acceptable the information materials are for people with thoracic aortic disease. It does not test any new treatments but aims to improve how studies are explained to patients.
NottinghamAges 18 years+ - NCT07575347Recruiting
Gum Disease and Rare Kidney Disorders Study
This study explores whether people with certain rare kidney diseases or chronic kidney problems have more gum disease than others. Researchers will examine your teeth and gums to understand the connection and help improve care for people with kidney conditions.
BucharestAges 18 years+ - NCT07572955Recruiting
Understanding Fluid Changes in Hospitalized Heart Failure
This study observes patients admitted to the hospital with heart failure that has suddenly worsened. Researchers will use daily ultrasound scans of your lungs to track fluid buildup and understand how the heart failure progresses during your hospital stay.
Rochester, MinnesotaAges 18 years+ - NCT07569887Recruiting
Brain Imaging Study of Arteriovenous Malformations Before and After Surgery
This research study uses special brain imaging scans to understand how an unruptured arteriovenous malformation (an abnormal tangle of blood vessels in the brain) affects blood flow and thinking abilities before and after surgical treatment. The goal is to learn how surgery impacts brain function and cognition in patients like you.
Montpellier, FranceAges 18 years+ - NCT07576647Recruiting
Improving stroke research recruitment for better outcomes
This study aims to make stroke research more inclusive by improving recruitment methods. It includes people with suspected TIA or minor stroke seen in urgent clinics, as well as those hospitalized for ischemic stroke or bleeding in the brain.
Calgary, AlbertaAges Any age
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.