Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,982 recruiting studies in this area right now.
By phase
- Not applicable7,962
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke844
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California465
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas118
Recruiting studies9,979 total
- NCT07479992Recruiting
Using AI to detect aortic stenosis from ECG
This study tests a new AI tool that can spot aortic stenosis (a narrowed heart valve) by analyzing your ECG. It may help find the condition earlier, when treatment is more effective.
BonnAges 18 years+ - NCT05432856Recruiting
Track metabolic health habits during breast cancer treatment
This study follows how “metabolic health” patterns (like eating timing and daily activity) change over time during breast cancer care. It may help researchers learn which habit patterns are linked to better outcomes and comfort during chemotherapy.
Edmonton, AlbertaAges 18 years+ - NCT07698522Recruiting
Digital therapy for arm movement after stroke
This study tests a digital therapy program to help people who have had a stroke improve arm and hand movement. It is for people who still have some arm function and can come to the lab often for 3 weeks.
Salt Lake City, UtahAges 30–85 - NCT07712198Recruiting
AI predicts muscle loss risk in brain injury ICU patients
This study uses artificial intelligence to predict which brain injury patients in the intensive care unit are at risk for muscle loss (sarcopenia). It aims to help doctors identify and prevent this complication early.
TrabzonAges 18–65 - NCT07709780RecruitingPhase 3
Comparing two blood thinners for left ventricle blood clots
This trial compares the blood thinner apixaban to warfarin for treating blood clots in the main pumping chamber of the heart (left ventricle). The goal is to see which medicine is better at preventing strokes and other complications.
Tucson, ArizonaAges 18 years+ - NCT07711106Recruiting
Comparing expert IVUS to standard IVUS for left main artery stenting
This study compares two ways of using a special ultrasound camera (IVUS) inside your heart's main artery during stenting. The goal is to see if a new 'expert' computer system helps the doctor place the stent better than the standard IVUS method. It may help people with blockages at the Y-shaped split of the left main artery.
Saint PetersburgAges 18 years+ - NCT07672210Recruiting
Pregnancy-related aortic dissection in China
This study is looking at cases of aortic dissection that happen during pregnancy or shortly after childbirth in China. It aims to understand how these events occur and how they can best be managed.
Shanghai, Shanghai MunicipalityAges 16–55 - NCT07060274Recruiting
How fast does the halo sign vanish after steroids in GCA?
This trial is for people newly diagnosed with giant cell arteritis (GCA) who have a 'halo' sign on their temporal artery ultrasound. It will study how quickly the halo disappears after starting steroid treatment, helping doctors understand the best way to use steroids for this condition.
Le Mans, SartheAges 50 years+ - NCT07711821Recruiting
Heart failure screening in primary care for older adults
This trial is testing a simple screening tool to find early signs of heart failure in people aged 50 or older, especially those with risk factors like diabetes or high blood pressure. If you're at risk, this could help catch heart problems sooner.
AmadoraAges 49 years+ - NCT07225075Recruiting
Silk Vista Baby flow diverter for brain aneurysms
This trial tests a device called Silk Vista Baby that is placed inside a blood vessel to treat a brain aneurysm (a weak spot in a blood vessel) that hasn't burst. The goal is to see if it helps prevent the aneurysm from growing or bursting.
Thousand Oaks, CaliforniaAges 22–80 - NCT07703618Recruiting
Does arm massage and tapping prevent IV irritation?
This study tests whether gentle massage and tapping on your arm near the IV site can lower the chance of irritation (phlebitis) from the IV. If you qualify, you would do simple hand and arm motions for a short time each day while you have the IV.
Bogotá, Bogota D.C.Ages 18–110 - NCT07620262Recruiting
Combined atrial fibrillation treatment and stroke prevention study
This study tests a new approach for people with atrial fibrillation (a type of irregular heartbeat) who are also at high risk for stroke. It combines a procedure to fix the heart's electrical signals with closing off a small pouch in the heart to reduce stroke risk, potentially avoiding long-term blood thinners.
Bay Shore, New YorkAges 18 years+ - NCT06337708RecruitingPhase 2
Smart Walk: App for African American women to get active
This study tests whether a smartphone app designed specifically for African American women can help you become more active. The app provides a personalized physical activity program and support through your phone, with the goal of improving your health and well-being.
Phoenix, ArizonaAges 24–65 - NCT07709858Recruiting
Outcomes after TAVR for severe aortic valve disease
This is a registry study that tracks how people do after a TAVR procedure for a severely narrowed aortic heart valve. It helps doctors learn more about long-term outcomes and improve care for future patients.
SeoulAges 18 years+ - NCT06041594Recruiting
Treating pulmonary embolism with the Laguna thrombectomy system
This trial tests a device (Laguna Thrombectomy System) to remove blood clots in the lungs. It may help people with a recent pulmonary embolism who are stable enough to undergo a minimally invasive procedure.
Birmingham, AlabamaAges 18–85 - NCT02359812Recruiting
Robot-assisted arm and hand rehab after recent stroke
This study tests whether a robot-guided therapy program can help people regain arm and hand movement after a recent stroke. You may be able to join if you are within a month of a first stroke on one side and have specific levels of arm and hand recovery.
Baltimore, MarylandAges 18–85 - NCT04879043RecruitingPhase 1/Phase 2
Safety study of HDP-101 for relapsed myeloma patients
This early-phase trial tests whether HDP-101 is safe and can potentially help adults with multiple myeloma that has come back or didn’t respond to standard treatments. It focuses on people who have already tried key myeloma medicines and still have measurable disease.
Atlanta, GeorgiaAges 18 years+ - NCT07347665Recruiting
Endovascular therapy for M2 segment stroke
This study tests whether a minimally invasive procedure to remove a blood clot from a specific branch of a brain artery (the M2 segment) helps people recover from a stroke better than standard care alone. It is for people who have had a moderate to severe stroke within the past 24 hours and could not get clot-dissolving medicine or it didn't work.
Nishinomiya, HyōgoAges 18–84 - NCT06723106Enrolling by invitationPhase 1
Long-term safety study of RAY121 for immune conditions
This study is for people who already took RAY121 in a previous trial and did well. It tests whether continuing the treatment is safe and effective over a longer period. The goal is to manage chronic immune conditions.
Camperdown, New South WalesAges 18–85 - NCT01524276Recruiting
Registry to track outcomes of Medtronic medical devices
This is a follow-up registry that collects information from people who have (or will receive) an eligible Medtronic device. It helps the company and doctors better understand how the device works in real-world use.
Birmingham, AlabamaAges Any age - NCT02359253Recruiting
Robot-assisted arm therapy after a recent stroke
This study tests whether robot-guided therapy can improve arm and hand recovery after a stroke. You may be a candidate if your stroke was recent and you still have certain levels of arm weakness and movement.
Baltimore, MarylandAges 18–85 - NCT06461988RecruitingPhase 2
Talquetamab and lenalidomide after stem cell transplant for myeloma
This trial tests combining two drugs, talquetamab and lenalidomide, as maintenance therapy after a stem cell transplant for multiple myeloma. The goal is to see if this combination helps keep the cancer from coming back.
Palo Alto, CaliforniaAges 18 years+ - NCT07499661Recruiting
Study of blood clots in the lungs with heart failure
This study looks at whether a blood clot in the lungs (pulmonary embolism) is a hidden cause in patients who are hospitalized for acute heart failure. It involves additional imaging tests to find a clot if present, which could change your treatment.
AgenAges 18 years+ - NCT04984473Recruiting
Breathing muscle training during heart rehab
This study tests whether breathing muscle training, added to regular heart rehab, can improve how well people with heart failure do day-to-day. It also compares results with healthy volunteers who do not have certain health problems.
Rochester, MinnesotaAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,982 recruiting cardiology studies from the U.S. registry right now, out of 15,268 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.