Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT05443633Recruiting
Brain and speech training for people with aphasia
This study looks at ways to improve language (speaking and understanding) for people with aphasia caused by stroke or dementia, using MRI to study brain function. It may help by testing language-focused approaches and how brain activity changes during treatment.
Tucson, ArizonaAges 21–80 - NCT06377449Recruiting
Lung ultrasound for better outcomes after heart surgery
This study tests whether using ultrasound to look at the lungs during and after heart surgery helps improve recovery. You may be eligible if you are having open-heart surgery with a heart-lung machine and meet certain health criteria.
Saint Petersburg, Sankt-PeterburgAges 18 years+ - NCT06236373Recruiting
Understanding cancer survivors' needs in Reggio Emilia
This study aims to understand the challenges and needs of people who have survived certain cancers (breast, prostate, thyroid, colorectal, multiple myeloma, or lymphoma) and their caregivers. It uses interviews or focus groups to gather perspectives.
Reggio Emilia, Reggio EmiliaAges 18 years+ - NCT06424756RecruitingPhase 2
Antioxidant supplement for blood vessel health
This study tests whether an antioxidant supplement can improve blood vessel health in healthy adults. It compares the supplement's effects in non-Hispanic Black and non-Hispanic White participants to see if there are differences in how blood vessels respond.
Athens, GeorgiaAges 18–75 - NCT07580547Recruiting
Atrial fibrillation ablation: study on sex differences
This research compares how atrial fibrillation (AF) affects men and women differently. If you are having your first catheter ablation for AF and are between 18 and 80, this study may help doctors understand outcomes better.
Be’er Ya‘aqovAges 18–80 - NCT07582432RecruitingPhase 3
Gamunex for Blood Cancer Patients With Low Antibodies
This trial tests whether Gamunex, an antibody replacement therapy, helps patients with chronic lymphocytic leukemia, multiple myeloma, or non-Hodgkin lymphoma who have low immunoglobulin (antibody) levels. The treatment may reduce infections and improve how well the body fights disease.
St. Petersburg, FloridaAges 18 years+ - NCT07585968Recruiting
New Catheter Treatment for Dangerous Heart Rhythms
This trial tests a new catheter-based procedure to treat life-threatening irregular heartbeats (ventricular tachycardia) that keep coming back despite medication. If you've had a heart attack and your implanted defibrillator hasn't fully controlled these arrhythmias, this procedure might help prevent future episodes.
Indianapolis, IndianaAges 18–85 - NCT07585097Recruiting
Long-term Safety Study of Odevixibat for Alagille Syndrome
This study follows patients with Alagille syndrome who are taking odevixibat to see how safe the medicine is over time. Alagille syndrome is a rare liver disease that affects bile flow, and odevixibat is a treatment that may help reduce itching and improve liver function.
BronAges 6 months+ - NCT07581210RecruitingPhase 2
QD202 Study for Recent Stroke Treated With Clot-Busting Medicine
This study tests whether a new drug called QD202 can help protect the brain and improve recovery when given alongside standard clot-busting therapy (thrombolysis) for acute ischemic stroke. You would be in the trial if you had a stroke in the last 24 hours and are receiving or planning to receive thrombolytic treatment.
Meizhou, GuangdongAges 18–85 - NCT07579234RecruitingPhase 3
New drug F182112 for hard-to-treat multiple myeloma
This trial tests a new drug called F182112 against standard treatments for multiple myeloma that has stopped responding to previous therapies. The goal is to see if F182112 works better and is safe for patients whose cancer has become resistant to multiple drug classes.
TianjingAges 18 years+ - NCT07583446RecruitingPhase 2/Phase 3
Istaroxime for acute heart failure with low blood pressure
This trial tests an investigational drug called istaroxime for people hospitalized with acute heart failure and low blood pressure (cardiogenic shock). The drug aims to improve heart function and stabilize blood pressure, potentially helping you feel better and recover.
YerevanAges 18–80 - NCT07581431RecruitingPhase 1
Testing ISM8969 in healthy and obese adults with heart disease risk
This early-stage trial tests a new drug called ISM8969 to see if it's safe and how the body handles it. Participants are either healthy adults or adults who are overweight with risk factors for heart disease, like high blood pressure or high cholesterol.
Melbourne, VictoriaAges 18–80 - NCT06692140Recruiting
Comparing two types of stents for heart artery treatment
This trial compares a newer type of stent (with very thin struts and a coating that dissolves) to a standard stent in people having a heart artery procedure. It aims to see if the new stent works as well or better.
AalborgAges 18 years+ - NCT07577596RecruitingPhase 4
Continuous Furosemide Infusion for Heart Failure Fluid Overload
This study tests whether giving furosemide (a water pill) as a continuous IV drip works better than standard doses for patients hospitalized with heart failure and fluid buildup. The goal is to help your body get rid of excess fluid more effectively.
RandersAges 18 years+ - NCT07580443Recruiting
Quality of Life After Open Surgery for Complex Aortic Aneurysms
This study follows patients who have had open surgery to repair complex abdominal aortic aneurysms—bulges in the main blood vessel in the belly. Researchers will ask you about your quality of life after surgery to understand how well people recover and feel.
LucerneAges 18 years+ - NCT07581587Recruiting
Breathing Exercises and Brain Function in Heart Failure
This study tests whether special breathing exercises—done alone or while doing a mental task—can improve memory and thinking skills in people with heart failure. Researchers want to see if training your breathing muscles helps your brain work better.
Istanbul, FatihAges 40 years+ - NCT07577336Recruiting
Portable MRI for children with oxygen-related brain injury
This study tests whether a small, portable MRI scanner can safely take pictures of the brain in seriously ill children who may have brain injury from lack of oxygen. It could help doctors diagnose and treat these children faster, without moving them from the ICU.
Kansas City, MissouriAges Up to 17 years - NCT07583940Recruiting
Energy Intake and Blood Pressure in College Athletes
This study looks at whether not eating enough calories affects blood pressure in Division I college athletes. Researchers want to understand if improving nutrition can help prevent high blood pressure in young athletes.
Greensboro, North CarolinaAges 18–26 - NCT07579871Recruiting
Sleep patterns and recovery after first stroke
This study looks at how sleep affects recovery in people who have had their first ischemic stroke (a stroke caused by a blood clot). Researchers want to understand whether sleep quality influences how well patients regain function after stroke.
Lund, Skåne CountyAges 18 years+ - NCT07579026Recruiting
Breathing exercises for pregnant women with POTS
This study tests whether special breathing exercises can help pregnant women with POTS (a condition where your heart races when you stand up). POTS causes dizziness, lightheadedness, and fainting, and this trial aims to see if breathing retraining makes these symptoms better during pregnancy.
Sialkot, Punjab ProvinceAges 19–35 - NCT07585760RecruitingPhase 2
Two-drug treatment for newly diagnosed myeloma with kidney problems
This trial tests a combination of two drugs, CM336 and isatuximab, for people newly diagnosed with multiple myeloma who also have kidney problems caused by the disease. The goal is to see if this combination can help control the myeloma while also improving kidney function.
TianjinAges 18–80 - NCT07579962RecruitingPhase 2
Bleomycin with electrical current for low-flow vascular malformations
This study tests a treatment called bleomycin electrosclerotherapy (BEST) for people with low-flow vascular malformations—abnormal clusters of blood or lymph vessels that can cause pain or swelling. The treatment combines a drug (bleomycin) with a small electrical current to shrink these abnormal vessels, and the goal is to see if it helps when other treatments haven't worked well or the problem came back.
LjubljanaAges 18–99 - NCT07582848Recruiting
Breastfeeding Support for Babies with Heart Disease
This study helps mothers of babies born with heart defects learn to breastfeed directly, even when the baby needs heart surgery in the first month of life. Researchers want to see if direct breastfeeding improves health outcomes for both mother and baby during this critical time.
Phoenix, ArizonaAges 18 years+ - NCT07584187Recruiting
Brain monitoring during emergency heart-lung support treatment
This study uses special monitoring devices to measure brain activity in patients receiving emergency mechanical heart-lung support (ECMO). The goal is to help doctors quickly predict which patients might recover neurologically and guide early treatment decisions.
ViennaAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.