Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,607 recruiting studies in this area right now.
By phase
- Not applicable5,333
- Phase 2607
- Phase 1559
- Phase 3418
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 384
Top conditions
- Obesity620
- Ovarian Cancer335
- Pancreatic Cancer287
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus183
- Diabetes Mellitus, Type 2171
- Hypertension138
- Type 1 Diabetes130
- Metabolic Syndrome126
- Obesity & Overweight124
- Breast Cancer110
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Colorectal Cancer90
- Pancreas Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- Eli Lilly and Company41
- M.D. Anderson Cancer Center41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California520
- Maryland180
- Alabama176
- Arizona171
- Florida166
- Texas158
- Massachusetts150
- New York142
- Colorado115
- Pennsylvania113
Recruiting studies7,607 total
- NCT07663136Recruiting
Finding early type 1 diabetes signs
This study looks for early signs of type 1 diabetes in people who have donated samples to the Indiana Biobank. It may help identify who is at risk, which could lead to earlier care.
Indianapolis, IndianaAges 1–99 - NCT07658755Recruiting
LiverSeek: Finding advanced liver scarring in MASLD
This study uses routine blood tests to find people with advanced liver scarring caused by a condition called MASLD. If you are between 50 and 75, have certain metabolic risks, and get blood work from your primary care doctor at select centers, you may be eligible.
Madrid, MadridAges 50–75 - NCT07662330Recruiting
Spermidine for weight and cholesterol in overweight adults
This trial tests if a natural supplement called spermidine can help lower cholesterol and body weight in overweight people with high cholesterol. You cannot be on any cholesterol or diabetes medications.
Shanghai, Shanghai MunicipalityAges 18–60 - NCT07660445Recruiting
Endoscopic stomach reshaping and duodenal procedure for obese type 2 diabetes
This trial tests a procedure that reshapes the stomach and treats the upper intestine to help control blood sugar and weight in people with obesity and type 2 diabetes. It may be an option if you have a moderate to high need for metabolic surgery.
ShatinAges 18–70 - NCT07660627Recruiting
ctDNA test for tracking cancer after treatment
This trial uses a blood test to find tiny bits of tumor DNA after treatment. It helps doctors see if any cancer remains, which could guide next steps for people with esophageal, stomach, or pancreatic cancer.
BrnoAges Any age - NCT02832388Recruiting
Study of primary aldosteronism in Western Norway
This study is looking at people with primary aldosteronism (a hormone condition that can affect blood pressure and salt balance) to better understand the condition. It may help researchers learn what causes problems and how to manage them, including for some participants who do a heart MRI.
BergenAges 18–85 - NCT06668649Recruiting
Polish fatigue scale study for MS, ALS, or stroke
This study tests a Polish version of a scale that measures how tired people feel. It's for people with MS, ALS, or stroke, or healthy volunteers.
Krakow, Lesser Poland VoivodeshipAges 18 years+ - NCT06626360Recruiting
Screening for malnutrition in people with obesity
This study looks at whether overweight or obese patients may also be malnourished. Researchers will screen people with a BMI of 25 or higher to find hidden malnutrition so they can get the right nutritional support.
AmsterdamAges 18 years+ - NCT06681610Recruiting
Testing pulse stimulation to improve movement in ALS
This trial studies if a non-invasive pulse stimulation can help people with ALS move better. It aims to see if this treatment can improve motor function.
Barcelona, CataloniaAges 21–80 - NCT06680492Recruiting
Nutrition and muscle health after weight loss surgery
This study looks at how nutrition affects muscle strength and function in people who have bariatric surgery. It may help you understand how to keep your muscles healthy after surgery.
Montreal, QuebecAges 18–65 - NCT06680791Recruiting
Endometrial cancer study on recurrence prevention and lifestyle
This study looks at how your cancer type and daily habits might help prevent endometrial cancer from coming back. It only requires that you've had endometrial cancer and a hysterectomy.
PragueAges Any age - NCT04447742Recruiting
Study of how healthy babies’ gut microbes develop from birth
This study follows pregnant people from about 20 weeks until delivery, to understand how gut microbes (tiny organisms in the intestines) develop in healthy babies. It may help researchers learn how early-life gut development affects health later on.
BernAges 18–45 - NCT06671665Recruiting
Manual therapy for low back pain in women with osteopenia
This study tests if manual therapy (hands-on treatment by a therapist) can reduce low back pain in postmenopausal women who have osteopenia, a condition where bones are weaker than normal but not yet osteoporosis. It aims to help with pain located in the lower back area.
GizaAges 50–60 - NCT05554224Recruiting
Personalized treatment based on obesity-related fatty liver tests
This study uses multiple types of health data (“multi-omics”) to help choose a personalized treatment plan for people with obesity-related fatty liver disease. It may help match treatment to your biology to improve outcomes.
Reus, TarragonaAges 18 years+ - NCT07651306Recruiting
Bone Loss After Stroke: New X-ray Detection Method
This study tests whether a new way of measuring X-rays can detect bone loss in the shoulder after a stroke. The research may help doctors identify patients at risk for fractures earlier.
IstanbulAges 18 years+ - NCT07649317RecruitingPhase 1
Ketoconazole effects on cortisol rhythms in mild adrenal hormone changes
This study tests whether the drug ketoconazole can safely help regulate daily cortisol patterns in people with mild autonomous cortisol secretion (MACS), a condition where the adrenal glands make too much cortisol. It will compare how patients with MACS and healthy volunteers respond to the medication.
Bethesda, MarylandAges 18–100 - NCT07650123Recruiting
7-Ketolithocholic Acid for Prediabetes Treatment
This study tests whether a compound called 7-ketolithocholic acid can help people with prediabetes (blood sugar levels higher than normal but not yet diabetic) prevent or delay developing type 2 diabetes. Participants will take the study medication while following a healthy diet and exercise plan.
BordigheraAges 18–70 - NCT07654972RecruitingPhase 1
Study of a new weight loss drug in healthy people with obesity or overweight
This study tests a new medication (LY4174794) for weight loss in people who are overweight or have obesity. It will help see if the drug is safe and how the body processes it.
San Antonio, TexasAges 18–65 - NCT07650682Recruiting
Blood Sugar and Hormone Patterns in Type 2 Diabetes
This study uses math models to understand how your blood sugar and hormones respond to food and insulin. You'll eat study foods and provide blood samples so researchers can better predict how your body handles diabetes.
Chicago, IllinoisAges 18–65 - NCT07653477RecruitingPhase 3
New diabetes drug for type 2 diabetes not well controlled with metformin
This trial tests an investigational drug called UBT251 for people with type 2 diabetes whose blood sugar is not well controlled despite taking metformin, either alone or with another diabetes medicine. The goal is to see if it can lower blood sugar levels more than a placebo.
ShanghaiAges 18–75 - NCT07652047RecruitingPhase 1
Safety Study of CX11 Tablets for Weight Management
This study tests whether a new medication called CX11 is safe and well-tolerated at different doses in people with overweight or obesity. The goal is to understand how the body responds to the drug before larger trials test whether it helps with weight loss.
Las Vegas, NevadaAges 18–55 - NCT07654374RecruitingPhase 3
Study of a new pill for weight loss and diabetes
This study tests a new daily pill (aleniglipron) to help adults with excess weight and type 2 diabetes lose weight and improve blood sugar control. It may be a good fit if you have a BMI of 27 or higher and your diabetes is managed with A1c between 6.5% and 10%.
Birmingham, AlabamaAges 18–79 - NCT07654361RecruitingPhase 3
A new pill for weight loss in obesity and overweight
This study tests an investigational pill called aleniglipron to see if it helps people with obesity or overweight who also have a weight-related health problem (like high blood pressure) lose weight safely. It is a Phase 3 trial, meaning it is in the final stages before seeking approval.
Birmingham, AlabamaAges 18–79 - NCT07653620Recruiting
Hydration and women's life stages
This study looks at how hydration affects women at different stages of life (before, during, and after menopause). You'll be asked to exercise, drink certain amounts of water, and sometimes limit fluids so researchers can see how your body responds.
Bradenton, FloridaAges 18–60
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,607 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,855 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.