Trauma
Injuries & trauma clinical trials
Wounds, fractures, and recovery from physical injury. We’re tracking 3,015 recruiting studies in this area right now.
By phase
- Not applicable2,560
- Phase 2122
- Phase 4114
- Phase 382
- Phase 181
- Phase 1/Phase 234
- Phase 2/Phase 322
Top conditions
- Traumatic Brain Injury151
- Spinal Cord Injuries142
- Spinal Cord Injury104
- Stroke64
- Trauma52
- Mild Traumatic Brain Injury40
- Amputation38
- Anterior Cruciate Ligament Injuries37
- Hip Fractures37
- Radiotherapy Side Effect37
- Rotator Cuff Tears35
- Spinal Cord Injuries (SCI)34
- Carpal Tunnel Syndrome28
- Anterior Cruciate Ligament Rupture27
- Burns27
- Cardiotoxicity27
- Carpal Tunnel Syndrome (CTS)26
- Breast Cancer25
Leading sponsors
- VA Office of Research and Development34
- Cairo University22
- Kessler Foundation19
- University of Miami19
- Zimmer Biomet19
- Johns Hopkins University18
- University of Florida18
- University of British Columbia17
- Mayo Clinic16
- Riphah International University16
Where studies are running
- California161
- Texas91
- Florida80
- New York78
- Illinois57
- Massachusetts55
- Pennsylvania50
- Minnesota45
- Ohio42
- Colorado41
Recruiting studies3,015 total
- NCT06840262Recruiting
Nerve surgery for pain after cancer amputation
This study tests two surgical techniques—target muscle re-innervation and regenerative peripheral nerve interfaces—alone or together, to help reduce pain felt in the remaining limb or the missing limb (phantom pain) after amputation for cancer. The goal is to find the best way to manage pain and improve quality of life.
Houston, TexasAges 18 years+ - NCT05448807RecruitingPhase 3
Phentolamine to reverse numbing from dental local anesthesia in kids
This trial studies whether phentolamine can quickly undo (reverse) the numbness from local anesthesia used during dental procedures in children. It may help kids feel normally sooner and safely use their mouth (like speaking and drinking) after treatment.
Cairo, El ManialAges 5–7 - NCT06538792Recruiting
Proprioception and strength after ACL reconstruction
This study looks at how well people regain body awareness, muscle strength, and fear of movement after ACL knee surgery. It may help understand recovery patterns in the first year after surgery.
IstanbulAges 18–35 - NCT06828107Recruiting
Testing a device to detect traumatic brain injury
This study tests a new device called SENSE to see if it can detect traumatic brain injury (TBI) quickly. You may qualify if you have a TBI with bleeding seen on a CT scan, or if you are a healthy volunteer without brain problems.
Gainesville, FloridaAges 22 years+ - NCT06830291Recruiting
Validating a digital cognitive test for head trauma patients
This study aims to validate a digital cognitive assessment tool (Neuralix) for people who have experienced moderate to severe head trauma within the past 5 years. Participation helps ensure the tool is accurate and useful for monitoring recovery.
ClamartAges 18–65 - NCT06828458Recruiting
Immune response to fungus in burn patients
This study looks at how the immune system fights fungus after a burn. It may help doctors understand which patients are at higher risk for infection and how to better protect them.
ParisAges 18 years+ - NCT06827483Enrolling by invitation
Balance and thinking test for young adults after ACL surgery
This study looks at how thinking skills affect balance in young adults who had ACL repair surgery in the past 5-7 months, compared to healthy young adults. You will do balance tasks and answer some questions.
Durham, North CarolinaAges 18–25 - NCT06828653Recruiting
Comparing 3D-printed vs standard ankle braces for walking
This study compares custom-made ankle-foot braces made with a digital 3D printing method versus the traditional plaster cast method. It aims to find out which type is more comfortable and effective for people with conditions like cerebral palsy, stroke, or spinal cord injury who need a brace to help them walk better.
Mississauga, OntarioAges 8 years+ - NCT06830655Enrolling by invitation
Climbing performance and body factors study
This study looks at how mobility, balance, and fatigue affect climbing performance. If you are a healthy climber, you may help researchers understand what makes a better climber.
Gdansk, GdańskAges 15–45 - NCT06834633Recruiting
Kidney protection for severe trauma patients
This trial tests a method to protect kidneys in patients with severe injuries who show early signs of kidney stress. If you or a loved one had a serious accident and are at risk for kidney damage, this study may offer extra monitoring or treatment.
Clermont-FerrandAges 18 years+ - NCT06835049RecruitingPhase 2
Heating therapy before surgery for high-risk soft tissue sarcoma
This trial tests a new approach for high-risk soft tissue sarcoma of the arm, leg, or trunk. Before surgery, you would receive chemotherapy combined with local hyperthermia (a treatment that gently heats the tumor area) to see if this can improve outcomes.
AarauAges 18 years+ - NCT06831981Recruiting
Heat therapy with chemo and radiation for rectal cancer
This trial tests if adding heat therapy (hyperthermia) to standard chemotherapy and radiation helps treat rectal cancer that has high-risk features. Heat therapy is thought to make cancer cells more sensitive to treatment.
Tübingen, Baden-WurttembergAges 18 years+ - NCT06097000Recruiting
Smart exoskeleton for leg recovery after spine surgery
This trial tests whether a powered exoskeleton can help people who have leg weakness after spinal surgery improve their walking at home. If you've had spinal surgery within the past year and can walk a bit, this device may help retrain your legs.
Beijing, Beijing MunicipalityAges 18–70 - NCT06333990RecruitingPhase 3
Quetiapine for concussion symptoms in veterans
This study tests whether quetiapine (a medication that can help with mood, sleep, and thinking) reduces ongoing concussion symptoms in veterans who had a mild traumatic brain injury (mTBI) at least 6 months ago. You may join if you are already taking at least three medications for your brain or mental health symptoms and have some PTSD symptoms.
Albuquerque, New MexicoAges 18–65 - NCT05455034RecruitingPhase 1/Phase 2
Blood and lung-sample test to guide treatment for lung inflammation
This Phase 1/2 study uses detailed “single-cell” testing (from lung samples) to better understand why lung inflammation happens after cancer radiation or immunotherapy. It aims to help choose the right treatment approach for people with radiation pneumonitis or immune checkpoint inhibitor pneumonitis.
Chongqing, Chongqing MunicipalityAges 18–80 - NCT06821516Recruiting
Comparing two nerve blocks for hip replacement pain
This study compares two different nerve block techniques to manage pain after a total hip replacement. The goal is to find out which method provides better pain relief and recovery.
Istanbul, Türki̇yeAges 18 years+ - NCT06816095Recruiting
Ozone therapy for pelvic pain after gynecological cancer treatment
This study is looking at whether ozone therapy can help relieve chronic pelvic pain caused by gynecological cancer treatments like radiation and chemotherapy. It aims to understand how the treatment works at a molecular level.
Las Palmas, Las PalmasAges 18 years+ - NCT06819904Recruiting
Combined talk therapy and balance rehab for mild TBI
This trial tests a new type of therapy that combines acceptance and commitment therapy (a counseling approach) with vestibular rehabilitation (exercises for balance and dizziness). It's designed for people with mild traumatic brain injury who still have symptoms like dizziness, anxiety, or memory problems.
Pittsburgh, PennsylvaniaAges 18–49 - NCT06817837Enrolling by invitation
Can hypnosis help adults with brain injury?
This study tests if hypnosis can help adults with stroke or traumatic brain injury who have symptoms like anxiety, trouble sleeping, pain, or behavior issues. Researchers want to see if it's a feasible and useful addition to usual care.
Tinlot, LiègeAges 18 years+ - NCT06819592RecruitingPhase 3
Preventing early lung infections after severe brain injury
This study tests whether giving an antibiotic (ceftriaxone) early after a severe brain injury can prevent lung infections caused by the breathing machine (ventilator). It is for adults in the ICU who recently started on a ventilator due to a brain emergency.
Canberra, Australian Capital TerritoryAges 18 years+ - NCT06820151Enrolling by invitation
Exploring injury and repair in the human esophagus
This study looks at how the esophagus heals after injury or surgery. It may help doctors find better ways to prevent or treat leaks that can happen after certain upper gastrointestinal procedures.
CambridgeAges 18–99 - NCT06823193Recruiting
How self-processing impacts mental time travel
This study explores how thinking about yourself affects your ability to imagine past or future events. It may help researchers understand how the brain connects self-awareness to memory and planning.
Castel Goffredo, MantovaAges 40–80 - NCT06818201Recruiting
Brain stimulation for ACL surgery recovery
This study tests if a gentle, noninvasive brain stimulation called tDCS can improve how your brain controls leg muscles and speeds up recovery after ACL surgery.
Valencia, ValenciaAges 16–40 - NCT04588311RecruitingPhase 3
Epoetin to improve outcomes in severe trauma ICU patients
This trial tests epoetin alfa (a blood-building medicine) to help reduce death and severe disability in critically ill trauma patients in the ICU. You may be considered if your ICU team expects a longer stay and the timing after injury is early.
Camperdown, New South WalesAges 18–75
Common questions
- How many injuries & trauma clinical trials are recruiting?
- Clin2 is tracking 3,015 recruiting trauma studies from the U.S. registry right now, out of 4,899 we cover in this area in total.
- What does “Injuries & trauma” cover here?
- Wounds, fractures, and recovery from physical injury. We group each study into injuries & trauma based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a injuries & trauma trial near me?
- Use the search to filter injuries & trauma studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.