Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,644 recruiting studies in this area right now.
By phase
- Not applicable4,309
- Phase 2852
- Phase 1471
- Phase 3427
- Phase 1/Phase 2310
- Phase 4209
- Phase 2/Phase 366
Top conditions
- Lung Cancer426
- Asthma194
- Non Small Cell Lung Cancer188
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD142
- Breast Cancer111
- COVID-19107
- Pulmonary Hypertension101
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Interstitial Lung Disease79
- Pneumonia79
- Cystic Fibrosis78
- Chronic Obstructive Pulmonary Disease (COPD)73
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca64
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama172
- Arizona155
- Massachusetts128
- Florida117
- New York113
- Maryland111
- Texas91
- Pennsylvania81
- Illinois72
Recruiting studies6,644 total
- NCT07528274RecruitingPhase 2
Microwave ablation with immunotherapy for advanced lung cancer
This trial tests combining microwave ablation (heat treatment of tumors) with two drugs—tislelizumab (an immune-boosting drug) and docetaxel (chemotherapy)—for patients with advanced non-small cell lung cancer whose disease progressed after initial immunotherapy. The goal is to see if this combination can slow or shrink tumors better than standard treatment alone.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT07529145Recruiting
Heart and Lung Fitness Testing During Lung Cancer Treatment
This study measures how well your heart and lungs work before and during lung cancer treatment using an exercise test. The goal is to understand how cancer treatment affects your physical fitness and help doctors better monitor your health.
Bialystok, Podlaskie VoivodeshipAges 18 years+ - NCT07529847Recruiting
Breathing Techniques to Help Asthma Control
This study compares two special breathing techniques—alternating which nostril you breathe through and a method called Buteyko breathing—to see which helps asthma patients breathe easier and improve lung function. You'll practice these techniques and we'll measure how well they work for you.
IslamabadAges 18–45 - NCT07530302Recruiting
Better ways to adjust CPAP therapy when it isn't working well
This trial tests whether a wearable device called Sunrise can help doctors adjust your CPAP machine better than standard sleep tests. If your current CPAP isn't stopping all your breathing pauses, this study may help find the right adjustments for you.
GrenobleAges 18–85 - NCT07530770Recruiting
Benralizumab for Severe Asthma with Aspergillus Allergy
This study tests whether benralizumab, a biologic medicine, works well in real-world settings for people with severe asthma caused by an allergic reaction to a common mold called Aspergillus. You may qualify if you have hard-to-control asthma despite strong medications and recent asthma flare-ups.
Jinan, ShandongAges 18–75 - NCT07531771Recruiting
Breathing Exercises for Early-Stage COPD
This study tests whether two types of breathing exercises—pursed lip breathing (slowing your breath) and alternate nostril breathing—can improve lung function and quality of life in people with mild COPD. You'll learn and practice these techniques to see if they help you breathe better.
IslamabadAges 40–65 - NCT07531810Recruiting
Nose Surgery Recovery and Patient Satisfaction Study
This study tracks how patients feel and function after nose surgery that uses a piece of cartilage (septal extension graft) to reshape the nose. Researchers want to understand both the benefits and any complications to improve future care.
Sivas, SivasAges 18 years+ - NCT07535437RecruitingPhase 1/Phase 2
New Drug Combination for Advanced Lung Cancer After Previous Treatment
This study tests a new combination of drugs (ivonescimab with either dato-DXd or osimertinib) for people with advanced lung cancer that has a specific EGFR gene mutation and has already been treated with other therapies. The goal is to see if this combination can help control the cancer better than current options.
Basking Ridge, New JerseyAges 18 years+ - NCT07535398Recruiting
Telehealth Exercise Program for High Lung Blood Pressure
This study tests whether people with elevated pressure in the blood vessels of the lungs can safely exercise at home using video sessions with therapists. It aims to see if remote rehabilitation can improve heart function and daily activity without requiring in-person visits.
Tokat ProvinceAges 18–65 - NCT07535463RecruitingPhase 1/Phase 2
Ivonescimab, chemotherapy, and radiation for lung cancer with brain tumors
This study tests a combination of a new immunotherapy drug (ivonescimab), standard chemotherapy, and focused radiation (stereotactic radiosurgery) for non-small cell lung cancer that has spread to the brain. The goal is to see if this combination can shrink tumors in both the lungs and brain.
Basking Ridge, New JerseyAges 18 years+ - NCT07536035Recruiting
Comparing Hospital Care Pathways for Acute Medical Illness
This study compares two different hospital care pathways for adults admitted with acute medical emergencies like infections, falls, or COPD flare-ups. The goal is to see which pathway provides more appropriate and effective care.
SingaporeAges 21 years+ - NCT07536256Recruiting
Youth Resilience Through Native Hawaiian Culture in Wai'anae
This program connects young people in the Wai'anae community with culturally rooted activities and support to build resilience and improve physical and mental health. You'll work with other youth and community organizations that use Native Hawaiian values to help you thrive.
Waianae, HawaiiAges 12–25 - NCT07536477Recruiting
High-flow oxygen versus standard oxygen for altitude lung swelling
This trial tests whether high-flow oxygen (delivered through a special nasal tube) works better than standard oxygen therapy for a condition called high-altitude pulmonary edema (HAPE)—fluid buildup in the lungs caused by rapid ascent to high altitude. The study aims to see which approach helps patients breathe better and recover faster.
Xigazê, TibetAges 18 years+ - NCT07536750Recruiting
Comparing Two Sedation Drugs for ICU Patients on Breathing Support
This study compares two medications (ciprofol and propofol) used to keep ICU patients calm and comfortable while they receive non-invasive breathing support, such as oxygen masks or tubes that help them breathe without a breathing tube in their windpipe. Researchers want to see which drug works better and is safer.
Guangzhou, GuangdongAges 18 years+ - NCT07537517Recruiting
Understanding heart failure and blood vessel pressure changes
This research study examines how certain biological pathways work in patients with heart failure who need heart catheterization (a procedure to measure heart pressures). By understanding these pathways, researchers hope to develop better treatments for pulmonary hypertension, a condition where blood pressure in the lungs becomes dangerously high.
Madrid, MadridAges 18 years+ - NCT07538947Recruiting
Real-time imaging to diagnose lung cancer faster and safer
This trial tests a new camera tool (confocal laser endomicroscopy) that lets doctors see lung tissue in real-time during a biopsy procedure. The goal is to diagnose non-small cell lung cancer more quickly and safely than standard biopsies alone.
NancyAges 18 years+ - NCT07540572RecruitingPhase 1
Testing IDE574 safety and effectiveness in advanced solid tumors
This early-stage trial tests a new drug called IDE574 to see if it is safe and effective in treating advanced cancers that have spread or stopped responding to standard treatments. The trial focuses mainly on hormone-receptor positive breast cancer, but also includes lung, prostate, and colorectal cancers.
Plantation, FloridaAges 18–99 - NCT07541638Recruiting
Early Lung Fibrosis Detection in Rheumatic Diseases
This study helps doctors identify early signs of lung scarring (fibrosis) in patients with autoimmune diseases like scleroderma, rheumatoid arthritis, and Sjögren's syndrome. By catching this early, researchers hope to better understand and treat these complications.
RomaAges 18–75 - NCT07542301Recruiting
Breathing Patterns in Premature Babies During Extubation
This study watches how premature babies breathe before and after removal of their breathing tube. By measuring breathing patterns, doctors hope to better understand when babies are ready to breathe on their own and improve outcomes.
Newark, DelawareAges birth–6 months - NCT07542366Recruiting
Testing a new lung imaging method in ICU patients
This study tests whether a special imaging technique called EIT (electrical impedance tomography) combined with a safe contrast injection can measure blood flow in the lungs of patients on breathing machines. If it works, it could help doctors better manage critically ill patients.
Wuhu, AnhuiAges 18 years+ - NCT07543588Recruiting
Physiotherapy assessment for unexplained breathing problems
This study evaluates how physiotherapy can help adults with unexplained breathlessness or breathing pattern problems. Breathing pattern disorder happens when your breathing becomes inefficient or irregular without an obvious lung or heart disease—and physio may help retrain how you breathe.
London, LondonAges 18 years+ - NCT07543601Recruiting
Better COPD care for people evaluated for lung cancer
This trial tests whether people being checked for possible lung cancer can also get improved care for a breathing condition called COPD (chronic obstructive pulmonary disease). It focuses on patients whose lung function tests show airflow problems.
VejleAges 18 years+ - NCT07545499Recruiting
Daily rhythms and physical recovery after COVID-19
This study looks at how your body's natural daily rhythms (sleep-wake cycles, energy patterns) affect physical function and daily activities in people recovering from long COVID. Understanding these patterns may help develop better recovery strategies.
Ankara, AltindağAges 18–65 - NCT07548060RecruitingPhase 2
New drug combination for advanced lung cancer after prior treatments
This trial tests two newer drugs (sacituzumab tirumotecan and furmonertinib) together for patients with advanced non-squamous lung cancer whose tumors have specific genetic mutations and have stopped responding to earlier EGFR-targeted drugs and chemotherapy. The goal is to find out if this combination can help patients whose cancer has progressed.
Tianjin, Tianjin MunicipalityAges 18–75
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,644 recruiting pulmonology studies from the U.S. registry right now, out of 10,689 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.