Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,749 recruiting studies in this area right now.
By phase
- Not applicable3,095
- Phase 4251
- Phase 2145
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University96
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University32
- Tanta University30
- Foundation University Islamabad27
- Mayo Clinic26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California158
- New York80
- Massachusetts68
- Florida65
- Texas52
- Ohio48
- Maryland42
- Minnesota41
- North Carolina38
- Illinois37
Recruiting studies3,748 total
- NCT07084935Recruiting
Comparing pain monitors during children’s surgery
This trial compares two devices that measure pain levels during surgery in children. It may help doctors better manage pain for children having planned surgery with general anesthesia.
Nijmegen, GelderlandAges 1–12 - NCT07085065Recruiting
Virtual reality for pain and anxiety during blood cancer procedures
This trial tests whether watching a virtual reality experience during a medical procedure can help reduce pain and anxiety for people with blood cancers. You may be able to take part if you are getting a bone marrow biopsy, spinal tap, blood draw, or chemotherapy.
Tunis, Sfax GovernorateAges 6 years+ - NCT07085247Recruiting
Role of bacteria in lower back disc disease
This trial looks at whether a specific bacteria, Cutibacterium acnes, is linked to disc problems in the lower back. If you're having surgery for a herniated disc, your tissue sample may help researchers understand the cause.
BrnoAges 18 years+ - NCT07089628Recruiting
Core stability and hand-eye coordination in rotator cuff injury
This study looks at how a rotator cuff tear affects your core stability, reaction time, hand-eye coordination, pain, and daily function. It compares people with rotator cuff problems to healthy individuals to understand these connections better.
AnkaraAges 18–65 - NCT07090096Recruiting
Plant-based diet study for endometriosis pain
This study tests whether a plant-based diet can help reduce pelvic pain in women with endometriosis. Participants are randomly assigned to either follow a plant-based diet or continue their usual diet for several months.
La Jolla, CaliforniaAges 18–45 - NCT07090356Recruiting
Soft tissue therapy versus stretching for athletes with piriformis syndrome
This study compares two techniques—instrument-assisted soft tissue mobilization and PNF stretching—to see which works better for reducing pain and improving movement in athletes with piriformis syndrome. It may help if you are an athlete with ongoing buttock or hip pain that makes sitting uncomfortable.
Lahore, Punjab ProvinceAges 18–35 - NCT07090928RecruitingPhase 4
Numbing medicine for less pain after knee scope surgery
This study tests whether giving bupivacaine (a numbing medicine) around the time of knee arthroscopy can reduce pain at the surgery sites and help you move your knee better after the operation.
Peshawar, KPKAges 18–70 - NCT07093138RecruitingPhase 4
CBD cream for migraine attacks
This trial tests whether a cream made with cannabidiol (CBD) can help stop migraine attacks. It is for people aged 18 to 55 who have had migraines for at least a year and get 2 to 8 attacks per month.
TehranAges 18–55 - NCT07093437Recruiting
Comparing ways to secure urinary catheters in ICU patients
This study compares two methods of securing a urinary catheter to the thigh to see which works better. It's for patients in the intensive care unit (ICU) who need a catheter for more than 48 hours.
BarcelonaAges 18–99 - NCT07094282Recruiting
Integrative therapies study for chronic back or neck pain
This study is testing integrative medicine therapies for chronic back or neck pain. It is for military members and their families who receive care at Nellis Air Force Base. The goal is to see if these therapies can help reduce pain and improve quality of life.
Nellis Air Force Base, NevadaAges 18 years+ - NCT07094386Recruiting
Pain relief study after open upper abdominal surgery
This trial compares two types of nerve blocks to control pain after open upper abdominal surgery. It aims to find which block works better and may help you recover with less pain.
CairoAges 18–60 - NCT07094997Recruiting
Massage therapy for healthcare workers with low back pain
This study tests if massage therapy can help healthcare workers with ongoing low back pain. If you qualify, you would receive several massage sessions to see if they reduce your pain and improve your well-being.
Wroclaw, Lower Silesian VoivodeshipAges 30–65 - NCT07095036Recruiting
Spinal cord stimulation and sensation study
This study looks at how a spinal cord stimulator affects your sense of touch and movement. It may help doctors better understand how this device works for people with chronic pain.
Chapel Hill, North CarolinaAges 18–85 - NCT07095556Recruiting
Laser therapy to help gums heal after tooth extraction
This trial tests whether a special laser treatment can help your gums heal better after a tooth is removed and the socket is prepared for a future dental implant. If you're having a tooth pulled and bone preservation, this laser might speed up healing and reduce pain.
Charleston, South CarolinaAges 18 years+ - NCT07096349Recruiting
Chronic pain study in severe hemophilia A
This study looks at chronic pain in people with severe hemophilia A. It aims to understand pain better through questionnaires and joint health checks.
Oviedo, Principality of AsturiasAges 18 years+ - NCT07097792Recruiting
Concussion recovery support program for headaches
This study tests a support program for young people who have had a concussion and are still having headaches. It aims to help them recover and feel better.
Seattle, WashingtonAges 18–29 - NCT07098390Recruiting
Relaxation to Reduce Fear and Pain After Joint Replacement
This study tests whether a simple relaxation technique (progressive muscle relaxation) can help reduce fear of falling, pain, and anxiety after hip or knee replacement surgery. It may be a safe, drug-free way to feel better during recovery.
AnkaraAges 18 years+ - NCT07098741Recruiting
Physical therapy for low back pain and pelvic tilt
This study looks at different physical therapy treatments for people with chronic, non-specific low back pain and a forward-tilted pelvis (anterior pelvic tilt). It aims to find which type of exercise or therapy works best to improve posture and reduce pain.
Chak Four Hundred Fifty-four, Punjab ProvinceAges 20–40 - NCT07099157RecruitingPhase 4
Brivudine for Shingles: Safety and Effectiveness Study
This trial tests whether the antiviral drug brivudine is safe and effective for treating shingles (herpes zoster). It compares brivudine to other antiviral treatments like famciclovir, and may be an option if you are looking for a shorter treatment course.
BeijingAges 18 years+ - NCT07099560Recruiting
Comparing two numbing blocks for hypospadias repair in children
This study compares two ways to numb the lower belly and groin area for children having hypospadias repair. It tests if a newer injection method (sacral erector spinae block) works as well as the standard method (caudal block) to control pain during and after surgery.
Tanta, El-Gharbia GovenorateAges 1–5 - NCT07100782RecruitingPhase 3
Estrogen & pain trial for endometriosis pelvic pain
This study tests whether a drug called relugolix CT can reduce pelvic pain from endometriosis. You'll have brain scans and pain tests to measure how your body processes pain. It might help if other treatments haven't worked well.
Ann Arbor, MichiganAges 18–49 - NCT07101250RecruitingPhase 4
Study of acetazolamide before laparoscopic hysterectomy
This trial tests a medication called acetazolamide given before surgery to see if it can help prevent shoulder pain after a laparoscopic hysterectomy. If you are a woman scheduled for this type of hysterectomy, you may be able to join.
Greenville, South CarolinaAges 21–65 - NCT07102446Recruiting
Opioid safety program for chronic pain patients without cancer
This trial tests a program to help manage opioid use safely for people with chronic non-cancer pain. If you take opioids for long-term pain and do not have cancer, this study may help improve your care.
Seoul, SeoulAges 19–79 - NCT07103135RecruitingPhase 1
Testing an accelerated TMS for chronic pain
This study tests an accelerated form of Transcranial Magnetic Stimulation (TMS) — a non-invasive treatment that uses magnetic pulses to stimulate the brain — to see if it can reduce chronic pain. If you have long-term pain that hasn't responded well to at least two medications, this trial might be a good option for you.
Minneapolis, MinnesotaAges 18 years+
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,749 recruiting pain medicine studies from the U.S. registry right now, out of 6,811 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.