Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,764 recruiting studies in this area right now.
By phase
- Not applicable3,111
- Phase 4251
- Phase 2144
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University97
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University32
- Tanta University30
- Foundation University Islamabad26
- Mayo Clinic26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California158
- New York80
- Massachusetts68
- Florida65
- Texas52
- Ohio48
- Maryland42
- Minnesota41
- Illinois38
- North Carolina38
Recruiting studies3,763 total
- NCT07373275Enrolling by invitation
Lifestyle Medicine for Teen Migraine
This study tests whether a lifestyle medicine program (like healthy habits and stress management) can help reduce migraine headaches in teenagers. It's for teens who get frequent migraines and are patients at certain MaineHealth clinics.
Scarborough, MaineAges 14–18 - NCT07371442Enrolling by invitation
Audio distraction and acupoint stimulation for kids during tooth extraction
This study tests two non-drug methods to help children feel less pain and worry during a tooth extraction: an audio-video distraction (like a movie or music) and a special pressure point (acupoint) stimulation on the hand. It aims to see which approach works best for kids ages 5 to 8 who need a baby tooth removed.
Al MansurahAges 5–8 - NCT07368738Enrolling by invitationPhase 4
IV Pain Meds for Shock Wave Lithotripsy
This study tests whether giving two pain relievers—acetaminophen (Tylenol) and ketorolac (an anti-inflammatory)—through an IV during shock wave lithotripsy helps control pain better than standard care. You may qualify if you need this kidney stone procedure and don't have certain health conditions.
Saint John, New BrunswickAges 19 years+ - NCT07362589Enrolling by invitation
Does pain education before knee or hip replacement help?
This study tests whether a special education session before knee or hip replacement surgery can help reduce anxiety, pain, and the need for pain medicine after surgery. If you are scheduled for joint replacement and can take part in a short learning session, you may be eligible.
Istanbul, KayişdağiAges 18 years+ - NCT07362407Enrolling by invitation
Cannabinoid treatment study for patients in Brazil
This study tracks how cannabis-based medicines work in real life. It looks at how people feel and function while using these treatments prescribed by their doctor.
Florianópolis, Santa CatarinaAges 18 years+ - NCT07352774Enrolling by invitation
Laughter therapy for breathing and pain in older adults
This study tests whether laughter therapy can improve breathing and reduce pain in people aged 60 and older. It may be a fun, drug-free way to feel better.
Ankara, AnkaraAges 60 years+ - NCT07352384Enrolling by invitation
Brain stimulation for chronic face and mouth pain
This trial tests if a non-invasive brain stimulation technique (called TMS or tDCS) can help reduce long-lasting pain in the face, jaw, or mouth. It's for people who have tried other treatments without enough relief.
Almada, Setúbal DistrictAges 18–75 - NCT07349914Enrolling by invitation
Shoulder Pain and Function with Heart Devices
This study looks at shoulder pain and how well the shoulder works in people who have a heart device like a pacemaker. It aims to understand if having the device affects shoulder function over time.
Ankara, SamanpazariAges 18 years+ - NCT07347457Enrolling by invitation
Rehab and pain relief for chronic low back pain
This trial tests whether a functional rehabilitation program can improve how your body naturally reduces pain after exercise. It may help people with chronic low back pain who are starting a rehab program.
Villeneuve-d'AscqAges 18–60 - NCT07345377Enrolling by invitation
Personalized brain stimulation for irritable bowel syndrome
This study uses brain stimulation (TMS) customized for each person to treat IBS. It uses MRI scans to see how the brain responds, aiming to find better ways to predict who will benefit from this therapy.
Hangzhou, ZhejiangAges 18–75 - NCT07331766Enrolling by invitation
Collaborative care for chronic pain patients
This trial tests a team-based treatment approach for people with chronic pain. You'll work with at least two pain clinic specialists to create a care plan that fits your needs.
Ottestad, InnlandetAges 18 years+ - NCT07326163Enrolling by invitation
Peppermint oil aromatherapy for fibromyalgia pain relief
This study tests whether smelling peppermint oil can help reduce pain and improve daily function in people with fibromyalgia, while also looking at cost. It uses a simple, non-invasive method (aromatherapy) to see if it can be a helpful addition to your current care.
Bilecik, BilecikAges 18 years+ - NCT07322185Enrolling by invitation
Comparing two bodywork methods for piriformis syndrome
This study compares two hands-on treatments, Stecco-fascial manipulation and Rolfing, for people with piriformis syndrome—a condition that causes buttock pain. The goal is to see which approach works better for reducing pain and improving movement.
Sambrial, Punjab ProvinceAges 25–45 - NCT07319806Enrolling by invitation
Two ways to help kids feel better during breathing tube removal
This study tests two different methods to lower pain, fear, and emotional upset when a breathing sample is taken from hospitalized children aged 6 to 12. The goal is to find which approach works best to make the experience easier for your child.
DüzceAges 6–12 - NCT07318116Enrolling by invitation
Cabbage Leaf for Knee Osteoarthritis Pain
This study tests whether applying cabbage leaves to the knee can reduce pain in people with knee osteoarthritis. If you have had knee pain for at least 6 months and are not allergic to cabbage, you may be able to join.
Şirnak, MerkezAges 18–80 - NCT07316348Enrolling by invitation
Vocalization and natural pushing during labor
This study looks at whether making sounds (vocalizing) and pushing naturally during the pushing stage of labor—without medication—can help first-time mothers. You'll be asked to try either vocal pushing or silent pushing, and the researchers will see how it affects your labor.
Istanbul, AtaşehirAges 18 years+ - NCT07316075Enrolling by invitation
Heart and metabolic health in silent pheochromocytoma or paraganglioma
This study looks at heart and metabolic health in people who have pheochromocytomas or paragangliomas that do not produce extra hormones. It aims to understand whether these 'silent' tumors affect cardiovascular and metabolic health, and how they compare to other cases.
AthensAges 18 years+ - NCT07313280Enrolling by invitation
PTSD and chronic pain therapy study for women
This study looks at how a psychological program can help women with chronic pain conditions linked to central sensitization (where the nervous system stays on high alert) and PTSD. It aims to reduce pain and stress symptoms.
Málaga, MálagaAges 18–65 - NCT07310823Enrolling by invitation
Manual therapy for neck-related headaches
This study tests if manual therapy (hands-on treatment) can help people whose headaches start from neck problems. If you have headaches at least once a week and limited neck movement, this trial may be an option.
GizaAges 20–40 - NCT07306312Enrolling by invitation
How thoughts affect low back pain with manual therapy
This study looks at how your thoughts and feelings about your chronic low back pain affect your pain and ability to move, during a course of manual therapy (hands-on treatment by a therapist). It may help you understand if your mindset influences your recovery.
AthensAges 18–65 - NCT07304037Enrolling by invitation
Skin-to-skin contact after birth for pain and satisfaction
This study looks at whether holding your baby skin-to-skin right after birth can help reduce your pain, improve your satisfaction with the birth, and affect your vital signs. If you had a healthy, full-term pregnancy and a vaginal birth without pain medication, you may be able to join.
IstanbulAges 18 years+ - NCT07295587Enrolling by invitation
Headache impact study for Libbs employees
This trial looks at how headaches affect employees at Libbs Pharmaceutical. It uses health data from the Dr. Cefaleia app to understand the burden of headaches at work.
São Paulo, São PauloAges Any age - NCT07287657Enrolling by invitation
Electrical acupoint stimulation after chest surgery
This trial tests a gentle, non-needle therapy that stimulates acupoints with mild electrical current to help you recover better after chest surgery. It may reduce pain and speed healing.
Taipei, HualienAges 15 years+ - NCT07272551Enrolling by invitation
Polyvagal therapy for chronic neck pain
This trial tests a new approach based on the polyvagal theory to help people with long-term neck pain. It uses gentle exercises and techniques to calm the nervous system and reduce pain.
Istanbul, MaltepeAges 18–50
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,764 recruiting pain medicine studies from the U.S. registry right now, out of 6,842 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.