Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,576 recruiting studies in this area right now.
By phase
- Not applicable2,951
- Phase 4240
- Phase 2131
- Phase 3102
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University60
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University21
Where studies are running
- California152
- New York79
- Massachusetts65
- Florida64
- Texas50
- North Carolina41
- Illinois40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,576 total
- NCT07577154Recruiting
Brain-Monitoring Anesthesia for Pediatric Throat Surgery
This trial tests a special brain-monitoring device (called Conox) during anesthesia for children having their tonsils and adenoids removed. The goal is to help doctors give the right amount of anesthetic medicine by watching your child's brain activity in real time.
KayseriAges 3–12 - NCT05605639RecruitingPhase 4
Study tests a targeted injection for neck pain
This trial studies whether an injection near the phrenic nerve can help people with neck pain. It is only for certain types of neck/diaphragm-related problems and excludes people with nerve, injury, cancer, infection, or autoimmune causes.
Dos Hermanas, SevilleAges 18–64 - NCT05816226RecruitingPhase 3
Topical cream for jaw joint pain
This Phase 3 study tests a skin-applied treatment (a cream or gel) to reduce pain in the jaw joint (TMJ). You may benefit if you have TMJ pain and can safely use the study medication without conflicting treatments.
San Francisco, CaliforniaAges 18 years+ - NCT05623176Recruiting
Study fairness in emergency surgery care during emergency laparotomy
This study looks at outcomes and whether emergency general surgery care is delivered fairly. It may help improve how hospitals support people having urgent abdominal surgery.
StockholmAges 16 years+ - NCT07574307Recruiting
Kinesio Tape for Meniscus Knee Injuries
This study tests whether special therapeutic tape (kinesiotape) can help reduce pain and improve function in people with meniscus injuries in the knee. The meniscus is a piece of cartilage that cushions your knee, and this trial sees if the tape can help your body heal without surgery.
BalıkesirAges 18–50 - NCT07569783Recruiting
Can brain stimulation reduce itching after C-section?
This study tests whether a gentle brain stimulation technique (tDCS) can reduce itching after a C-section. It is for women who are having a C-section with epidural anesthesia and morphine.
Nantong, JiangsuAges 18–40 - NCT07571473Recruiting
Monitoring stress during abdominal hysterectomy surgery
This study tests a new monitoring system called CoreSys that tracks your body's stress response during abdominal hysterectomy (surgical removal of the uterus). The goal is to help doctors better manage pain and stress during your operation.
Rosario, Santa Fe ProvinceAges 18–70 - NCT07573969RecruitingPhase 3
Pain Relief Medicines Added to Spinal Injection for Back Surgery
This trial tests whether adding one of two different medicines (dexmedetomidine or ketamine) to a numbing injection in the lower spine improves pain relief after back surgery. You would receive the injection while asleep during surgery to help manage pain afterward.
CairoAges 21–60 - NCT07576101Recruiting
Blood Flow Restriction Training for Lower Back Pain
This study tests whether a special exercise technique that carefully reduces blood flow to your legs while exercising can help reduce chronic lower back pain. The goal is to see if this method combined with training can strengthen your muscles and relieve pain more effectively.
IslamabadAges 18–45 - NCT07569549Recruiting
Thumb base arthritis surgery: joint replacement vs bone removal
This study compares two common surgeries for thumb base arthritis to see which one gives better pain relief and hand function. The results could help you and your doctor choose the best treatment option.
UppsalaAges 40–80 - NCT07576218Recruiting
Pilates and prone plank exercises for postpartum abdominal separation
This study tests whether Pilates and specific core exercises can help close the gap between abdominal muscles (called diastasis recti) that commonly happens after pregnancy. Diastasis recti can cause weakness and discomfort, and this trial evaluates whether these exercises improve that condition.
Lahore, Punjab ProvinceAges 18–45 - NCT07576244Recruiting
Core exercises and massage therapy for postpartum back pain
This study tests whether core-strengthening exercises combined with a hands-on massage technique called myofascial induction therapy can help reduce back pain after vaginal delivery. It may help you recover faster and manage pain without medication.
Sialkot, Punjab ProvinceAges 20–45 - NCT07569731Recruiting
Understanding Fibrous Dysplasia Through Patient Data and Tissue
This study collects information from patients with fibrous dysplasia (a bone condition where normal bone is replaced by fibrous tissue) and related syndromes to better understand the disease. Researchers will review your medical records, imaging scans, and stored tissue samples to learn more about how the disease develops and progresses.
Bologna, BOAges Any age - NCT07573527Recruiting
Online therapy for upper back muscle pain from trigger points
This study tests whether remote physical therapy (done online) can help relieve neck and upper back pain caused by tight knots in your rhomboid muscles. You would receive guided exercises and treatment through video calls instead of visiting a clinic in person.
Karachi, SindhAges 18–35 - NCT07569796Recruiting
Nerve Stimulation to Help Recover After ACL Surgery
This study tests whether stimulating your sciatic nerve (a major nerve in your leg) can help you recover better after ACL reconstruction surgery. The goal is to reduce pain and help you regain strength and movement.
Madrid, MadridAges 18–60 - NCT07576270Recruiting
Breathing exercises and massage after breast cancer surgery
This study tests whether special breathing exercises and massage techniques can help reduce pain, stiffness, and limited arm movement in people who've had breast cancer surgery. It may help improve shoulder function and quality of life after treatment.
Lahore, Punjab ProvinceAges 45–64 - NCT07571889Recruiting
Numbing spray to reduce Botox injection pain for chronic migraine
This study tests whether a numbing spray applied inside the nose before Botox injections can reduce injection pain in people with chronic migraine. The goal is to make the treatment more comfortable without affecting how well it works.
East Providence, Rhode IslandAges 18 years+ - NCT07571252RecruitingPhase 4
Pain Relief Before Jaw Surgery: A Study
This study tests whether taking pain medicine before jaw surgery (orthognathic surgery) helps reduce pain after the procedure. If you're having jaw surgery, this trial may help doctors understand the best way to manage your pain.
San JuanAges 21–65 - NCT07575555Recruiting
Lipedema's role in knee arthritis in women
This study compares women with knee arthritis who do or don't have lipedema (a condition causing painful fat buildup, usually in the legs) to understand how lipedema affects knee joint health. Results may help doctors better treat knee arthritis in women with lipedema.
Izmir, İzmirAges 30–65 - NCT07576296Recruiting
Shoulder exercises for rounded shoulders after pregnancy
This study tests whether specific shoulder blade exercises and stretches can help new mothers with rounded shoulders and shoulder discomfort. It aims to improve posture and reduce pain during the postpartum period.
Lahore, Punjab ProvinceAges 20–35 - NCT07576127Recruiting
Gongs Mobilization and Stretching for Frozen Shoulder
This study tests two hands-on treatment techniques—gongs mobilization and proprioceptive neuromuscular facilitation (a type of guided stretching)—to help reduce stiffness and improve movement in frozen shoulder. Frozen shoulder causes pain and loss of motion in the shoulder joint; this trial aims to see if these treatments can help restore function.
Rawalpindi, Punjab ProvinceAges 40–60 - NCT07576231Recruiting
Sacral Release and Lumbar Mobilization for Period Pain
This study tests two hands-on physical therapy techniques—sacral release and lumbar mobilization—to see if they can reduce severe period pain. If you have significant menstrual pain that isn't caused by an underlying condition, this trial may help you find relief.
Lahore, Punjab ProvinceAges 13–19 - NCT07576985Enrolling by invitation
IV Tylenol for Pain and Agitation After Throat Surgery in Young Children
This study tests whether giving acetaminophen (Tylenol) through an IV (a vein) instead of by mouth helps reduce pain and fussiness after tonsil and adenoid removal in children age 7 and under. The goal is to find better ways to keep children comfortable during recovery.
Cleveland, OhioAges Up to 8 years - NCT07576582Recruiting
Mud therapy for jaw joint pain
This trial tests whether a special mud treatment (peloid therapy) can reduce jaw joint pain and improve function in people with temporomandibular joint disorder. It is a non-drug approach that may help those who have had jaw pain for at least 4 weeks.
Uşak, MerkezAges 18–65
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,576 recruiting pain medicine studies from the U.S. registry right now, out of 6,474 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.