Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,504 recruiting studies in this area right now.
By phase
- Not applicable9,843
- Phase 2785
- Phase 1574
- Phase 3532
- Phase 4345
- Phase 1/Phase 2306
- Phase 2/Phase 3119
Top conditions
- Stroke852
- Parkinson Disease423
- Alzheimer Disease342
- Multiple Sclerosis339
- Dementia229
- Ischemic Stroke201
- Epilepsy196
- Insomnia156
- Obstructive Sleep Apnea156
- Traumatic Brain Injury155
- Spinal Cord Injuries151
- Sarcopenia150
- Acute Ischemic Stroke142
- Cerebral Palsy129
- Mild Cognitive Impairment128
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis106
Leading sponsors
- Beijing Tiantan Hospital135
- Riphah International University127
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University71
- National Taiwan University Hospital69
- University of Minnesota64
Where studies are running
- California677
- Massachusetts308
- New York294
- Florida278
- Texas270
- Maryland245
- Alabama214
- Arizona210
- Illinois193
- Pennsylvania177
Recruiting studies12,502 total
- NCT07635693Recruiting
ATLG Levels During Stem Cell Transplant for Multiple Sclerosis
This study measures how a specific immune-suppressing medication (ATLG) works in patients with multiple sclerosis who are undergoing autologous stem cell transplantation—a procedure where your own blood stem cells are removed, treated, and returned to help reset your immune system.
Milan, ItalyAges 18 years+ - NCT07635758RecruitingPhase 1/Phase 2
Stem Cell Treatment for Recent Stroke Recovery
This trial tests whether special cells from human placenta can help your brain recover after a recent stroke. The treatment is given as an injection and aims to reduce long-term disability.
BeijingAges 18–80 - NCT07635823Recruiting
Adaptive deep brain stimulation for Parkinson's disease
This study tests a new type of deep brain stimulation (DBS)—a surgical treatment that uses electrical pulses to help control Parkinson's symptoms. Unlike standard DBS, this system adapts automatically to your body's needs. You may qualify if you've never had DBS surgery or if you've had it before and are willing to switch to the new device.
Hefei, AnhuiAges 18 years+ - NCT07636720Recruiting
Sleep monitoring with Parkinson's deep brain stimulation device
This study uses a special sensing device in your existing Parkinson's deep brain stimulation implant to monitor your sleep patterns. Researchers want to understand how sleep and the stimulation device interact, which could help improve treatment for Parkinson's patients.
San Antonio, TexasAges 40–80 - NCT07636902Recruiting
Ultrasound to detect skull fractures in young children with head injuries
This study tests whether ultrasound (sound-wave imaging) can quickly and safely detect skull fractures in children 6 years old or younger who have bumped their head. The goal is to find a faster, non-radiation way to check for fractures in the emergency room.
Genova, ItalyAges Up to 6 years - NCT07637084Recruiting
Light therapy for chronic pain and fatigue in Ehlers-Danlos Syndrome
This trial tests whether a non-invasive light therapy called photobiomodulation can reduce chronic pain and fatigue in people with hypermobile Ehlers-Danlos Syndrome (hEDS), a genetic condition affecting connective tissue. The light is applied to the skin and may help cells produce energy and reduce inflammation.
Boulogne-Billancourt, Île-de-France RegionAges 18 years+ - NCT07637357Recruiting
How anesthesia affects thinking after weight-loss surgery
This study looks at how different types of anesthesia used during sleeve gastrectomy (a weight-loss surgery) may affect your memory and thinking skills after the operation. Researchers want to understand which anesthesia approach is safest for your brain.
Istanbul, SancaktepeAges 18–65 - NCT07637773Recruiting
Brain Stimulation for Depression and Loss of Interest in Older Adults
This trial tests a new brain stimulation technique called tACS (transcranial alternating current stimulation) to treat depression in people aged 60 and older, especially the symptom of losing interest in things you once enjoyed. Researchers believe this targeted stimulation may help improve mood and motivation.
Tianjin, Tianjin MunicipalityAges 60 years+ - NCT07637981RecruitingPhase 2
Safety Study of DX243 for Hearing Loss in Noise
This study tests a new medicine (DX243) to see if it is safe and well-tolerated in people with hearing difficulties, especially trouble hearing speech in noisy environments. The goal is to understand how the body processes this medicine and whether it might help improve hearing.
Liège, LiègeAges 18–75 - NCT07640555RecruitingEarly Phase 1
Brain imaging study for Parkinson's and related movement disorders
This research study tests a new type of brain scan (called a PET scan) that may help detect early signs of Parkinson's disease and similar conditions. You'll receive the scan and may have a spinal tap to check for specific protein markers.
New Haven, ConnecticutAges 50–80 - NCT07640711Recruiting
Brain-Computer Interface for High Spinal Cord Injury
This trial tests a surgically implanted brain-computer interface (BCI) system designed to help people with severe spinal cord injuries regain some ability to move or control devices using their thoughts. The device reads signals directly from the brain to bypass the injured spinal cord.
Utrecht, UtrechtAges 18–70 - NCT07641153Recruiting
Virtual Reality Games to Prevent Confusion After Surgery
This study tests whether playing cognitive games in virtual reality (VR—a computer-generated environment you interact with using a headset) can help prevent delirium (severe confusion) in older adults after major surgery. Delirium is common after surgery in seniors and can slow recovery; this trial explores whether VR brain exercises might reduce it.
Houston, TexasAges Up to 65 years - NCT07641569Recruiting
Dual-Task Training Methods for Parkinson's Disease
This study compares two different training approaches that combine cognitive (thinking) and physical exercises to help improve balance, walking, and daily functioning in people with Parkinson's disease. The goal is to find which method works better for maintaining independence and preventing falls.
Ankara, KeçiörenAges 40 years+ - NCT07641790Recruiting
Vibration Devices to Improve Arm Movement After Stroke
This study tests whether wearing small vibrating devices on your arm can help improve movement and function in the arm weakened by stroke. The vibrations may help retrain your brain and muscles to work together better during the recovery period.
Faisalābad, Punjab ProvinceAges 30–60 - NCT07642089Recruiting
Stretching and strength training for restless legs in pregnancy
This study tests whether gentle stretching and strength exercises can help pregnant women with restless leg syndrome—a condition that causes uncomfortable sensations in the legs and disrupts sleep. The goal is to see if these exercises reduce symptoms and improve sleep quality during pregnancy.
Lahore, Punjab ProvinceAges 18–35 - NCT07642154Recruiting
Balance and Sensory Training After Stroke
This study compares two types of physical therapy to help stroke patients improve balance, sensation in their legs, and confidence walking. The goal is to see which approach works better for people recovering from stroke.
Lahore, Punjab ProvinceAges 50–65 - NCT07642466Recruiting
Bladder Health and Life Quality in Spina Bifida
This study asks adults and teens with spina bifida about how their bladder care affects their daily life and well-being. Your answers will help doctors better understand what matters most to patients.
London, OntarioAges 13 years+ - NCT07642674Recruiting
IV Pain Relief After Shoulder Arthroscopy Surgery
This study tests whether an intravenous pain medication (dexketoprofen) given during shoulder arthroscopy can reduce pain that returns after surgery ends. Researchers want to see if this approach helps keep patients more comfortable and need fewer pain medications overall.
Eskişehir, OdunpazarıAges 18–70 - NCT07642856Recruiting
Brain Stimulation With Therapy for Cerebellar Disorders
This study tests a combination of gentle brain stimulation paired with specialized exercises designed to help people with cerebellar conditions—disorders affecting balance, coordination, and movement. The goal is to see if pairing these two approaches together works better than either alone.
Baltimore, MarylandAges 18–75 - NCT07642882Recruiting
Brain Stimulation for Fibromyalgia Pain Relief
This study tests whether a non-invasive brain stimulation treatment (rTMS) can reduce chronic pain in fibromyalgia patients. The treatment uses magnetic pulses to stimulate specific areas of the brain and may help relieve widespread pain.
Boulogne-Billancourt, Île-de-France RegionAges 18–80 - NCT07642908Recruiting
Brain imaging study of Parkinson's disease with LRRK2 gene mutations
This research study uses advanced MRI brain imaging to understand how a specific gene mutation (LRRK2) affects certain brain chemicals in people with Parkinson's disease. The goal is to learn more about how this genetic form of Parkinson's works, which could help develop better treatments.
Ann Arbor, MichiganAges 45 years+ - NCT07643337Recruiting
Vagus Nerve Stimulation With Rehab to Improve Walking After Stroke
This study tests whether vagus nerve stimulation (a small device that stimulates a nerve in your neck) combined with rehabilitation therapy can help improve walking and leg function in stroke survivors. You would be one of the first to try this combination approach for stroke recovery.
Buffalo, New YorkAges 22–80 - NCT07643363Recruiting
Brain Stimulation for Cognitive Impairment in Dementia
This study tests a new brain stimulation technique called temporal interference stimulation to help slow cognitive decline in people with Alzheimer's disease or frontotemporal dementia. Researchers will combine this stimulation with cognitive training to see if it improves memory and thinking skills.
Tianjin, Tianjin MunicipalityAges 45–85 - NCT07643558Recruiting
Fish oil and weight training for cancer patients' muscle health
This study tests whether taking fish oil supplements combined with progressive weight training exercises can help preserve or build muscle strength in cancer patients undergoing treatment. The goal is to help you maintain physical function and quality of life during cancer care.
Erlangen, BavariaAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,504 recruiting neurology studies from the U.S. registry right now, out of 19,972 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.