Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,406 recruiting studies in this area right now.
By phase
- Not applicable9,740
- Phase 2783
- Phase 1576
- Phase 3534
- Phase 4342
- Phase 1/Phase 2307
- Phase 2/Phase 3124
Top conditions
- Stroke841
- Parkinson Disease427
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke201
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia154
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke138
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California681
- Massachusetts299
- New York292
- Florida275
- Texas265
- Maryland246
- Arizona212
- Alabama210
- Illinois188
- Pennsylvania177
Recruiting studies12,404 total
- NCT07535593RecruitingPhase 2/Phase 3
Electrical Acupoint Stimulation for Consciousness Disorders
This trial tests a non-invasive treatment called transcutaneous electrical acupoint stimulation (TEAS) to help people recover consciousness after severe brain injury. The treatment uses mild electrical pulses on specific points on the hands and may help improve awareness and responsiveness.
Xi'an, ShaanxiAges 18–80 - NCT07103200Recruiting
Decision-making fatigue after traumatic brain injury
This study looks at how making decisions can feel more tiring after a mild or moderate traumatic brain injury compared to people without a brain injury. It uses computer tasks to measure fatigue.
Minneapolis, MinnesotaAges 18 years+ - NCT05788536RecruitingPhase 1/Phase 2
Gene therapy study for OTOF-related hearing loss
This trial tests a one-time gene therapy delivered into the ear to improve hearing in people with certain OTOF gene changes. It studies safety and how well the treatment can work, especially in children and infants, as doctors monitor hearing tests for up to 48 weeks.
Los Angeles, CaliforniaAges Any age - NCT07630649RecruitingPhase 2
Gene therapy for wet age-related macular degeneration in second eye
This study tests a one-time gene therapy injection (ixoberogene soroparvovec) in the second eye of people with wet age-related macular degeneration who have already responded well to anti-VEGF injections. The goal is to see if this gene therapy can help preserve or improve vision in that eye.
Phoenix, ArizonaAges 50 years+ - NCT07476092Recruiting
Digital games for thinking and visual skills
This study tests whether playing specially designed digital games can improve visual and thinking skills in young adults with mild to moderate intellectual disabilities. It is run by Koç University and takes place at EÇADEM, a center that supports people with special needs.
Istanbul, TürkiyeAges 18–35 - NCT05477277Recruiting
MRI testing during liver transplant evaluation
This study looks at whether having an MRI scan during liver transplant planning helps predict who may have worse outcomes or higher risk of death. It focuses on adults with severe liver disease who are already being considered for a transplant.
Phoenix, ArizonaAges 18 years+ - NCT07019922RecruitingPhase 3
A study of elsunersen for children with SCN2A-related epilepsy
This trial tests an experimental drug called elsunersen in children with a specific type of epilepsy caused by changes in the SCN2A gene. It aims to see if the drug can reduce seizures and be safe for children.
San Diego, CaliforniaAges 1 day–18 years - NCT07098286Enrolling by invitation
Home rehab after stroke
This study tests a high-intensity home-based rehabilitation program for people who have had a stroke. It aims to help you recover strength and function in the comfort of your own home.
Durham, North CarolinaAges 18 years+ - NCT07225686RecruitingPhase 3
Maridebart Cafraglutide for sleep apnea in adults on CPAP
This study is testing whether a new medicine, called Maridebart Cafraglutide, can help people with obstructive sleep apnea who are already using a CPAP machine. The medicine may help with weight loss and potentially improve sleep apnea. Participants will either receive the medicine or a placebo (an inactive substance), and the study lasts for several months.
Northridge, CaliforniaAges 18–99 - NCT07743892Recruiting
Sleep apnea and body awareness study
This study looks at how people with obstructive sleep apnea (OSA) sense and understand their bodies, which may help improve treatment. If you have been diagnosed with OSA, you might be able to join.
KarabükAges 18–65 - NCT07744854Recruiting
Monitoring breathing with sensors during sleep
This study tests two wearable sensors that track how hard you breathe while you sleep. It may help diagnose sleep and breathing problems without needing a hospital visit.
Taipei, TaiwanAges 18 years+ - NCT07050355Recruiting
Brain stimulation and exercise for depression after stroke
This study tests whether combining brain stimulation with aerobic exercise can help treat depression and improve walking in people who have had a stroke at least a year ago. If you have ongoing depressive symptoms and some leg weakness from your stroke, this treatment may help you feel better and walk more easily.
Durham, North CarolinaAges 21 years+ - NCT07744269Recruiting
Hand therapy for early complex regional pain syndrome
This trial compares two hand therapy techniques — contrast baths (alternating warm and cool water) and compression with whirlpool therapy — to see which better eases early-stage complex regional pain syndrome (CRPS) after a hand or wrist injury. If you've had hand or wrist trauma and are still in pain, this study might help you find a treatment that reduces discomfort and improves hand use.
Ankara, YenimahalleAges 18–80 - NCT07745673Recruiting
Study of targeted treatment for Parkinson's disease symptoms
This study compares different ways of targeting treatment for Parkinson's disease symptoms. It is designed for people with mild to moderate Parkinson's who have had symptoms for at least 2 years and are generally stable on their current medications.
Wuhan, HubeiAges 40 years+ - NCT06736548Enrolling by invitation
Sleep treatment program for cancer survivors
This study tests a sleep education program for cancer survivors who have trouble sleeping. You will learn strategies to improve your sleep and overall well-being.
Boston, MassachusettsAges 18–89 - NCT06944522RecruitingPhase 3
Cell therapy for Parkinson's symptoms
This study tests a new cell therapy called bemdaneprocel to see if it can reduce Parkinson's symptoms and “off” time. The treatment involves transplanting special cells into the brain to help replace lost dopamine-producing cells.
Scottsdale, ArizonaAges 45–75 - NCT07737665RecruitingPhase 4
Melatonin for better sleep in IBD patients in remission
This study tests whether melatonin (a natural sleep hormone) can improve sleep quality in people with inflammatory bowel disease (IBD) whose disease is quiet (in remission). If you have IBD and trouble sleeping, you may be able to join.
Bangkok Noi, BangkokAges 18 years+ - NCT06563895RecruitingPhase 3
Testing acoramidis to prevent ATTR amyloidosis in gene carriers
This trial tests a daily pill called acoramidis to see if it can prevent ATTR amyloidosis in people who carry a gene mutation but have no symptoms yet. It aims to stop the disease before it starts.
La Jolla, CaliforniaAges 18–75 - NCT06689878Recruiting
Mobile therapy for anxiety and depression after stroke
This study tests if a mobile cognitive behavioral therapy app can help reduce anxiety and depression in people who have had a stroke. If you are between 40 and 79 and have ongoing feelings of worry or low mood after your stroke, this therapy might be a convenient option.
New York, New YorkAges 40–79 - NCT07549893Recruiting
Coagulation of Middle Meningeal Artery During Brain Bleed Surgery
This trial tests a new technique during surgery for chronic subdural haematoma (bleeding between the brain and skull) where doctors use heat or special tools to seal a blood vessel (the middle meningeal artery) to help prevent the bleed from returning. The goal is to see if this addition to standard surgery is safe and feasible.
LondonAges 18 years+ - NCT06441331RecruitingPhase 1
Lu-177 edotreotide for children with SSTR-positive tumors
This trial tests a radioactive drug called Lu-177 edotreotide for children with a certain type of tumor (SSTR-positive) that hasn't responded to other treatments. The goal is to find the right dose and see how safe it is.
San Francisco, CaliforniaAges 2–18 - NCT06609213Recruiting
Testing a nutrition drink before feeding tube placement in ALS
This trial tests if drinking a special nutrition formula for a few weeks before getting a feeding tube can help people with ALS tolerate tube feeding better. It aims to reduce side effects like bloating or discomfort.
Fort Lauderdale, FloridaAges 18 years+ - NCT07299006Recruiting
Study of a robot to help manage pain during IV placement in children
This trial tests whether a friendly robot named Paro can help reduce pain and anxiety in young children when they need an IV placed. If your child is between 1 and 7 years old and needs an IV, this study may help make the procedure less stressful.
BrestAges 1–7 - NCT07245030Recruiting
Virtual reality vs show-do for dental anxiety in kids with hearing loss
This trial tests whether virtual reality or a show-do method works better to reduce dental anxiety in children who have moderate to severe hearing loss. If your child needs a dental cleaning, this could help make the visit less stressful.
Giza, Giza GovernorateAges 6–12
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,406 recruiting neurology studies from the U.S. registry right now, out of 19,323 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.