Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,941 recruiting studies in this area right now.
By phase
- Not applicable9,343
- Phase 2764
- Phase 1557
- Phase 3513
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke796
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis329
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management114
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California659
- Massachusetts305
- New York294
- Florida271
- Texas266
- Maryland248
- Alabama207
- Arizona207
- Illinois181
- Pennsylvania176
Recruiting studies11,941 total
- NCT07641153Recruiting
Virtual Reality Games to Prevent Confusion After Surgery
This study tests whether playing cognitive games in virtual reality (VR—a computer-generated environment you interact with using a headset) can help prevent delirium (severe confusion) in older adults after major surgery. Delirium is common after surgery in seniors and can slow recovery; this trial explores whether VR brain exercises might reduce it.
Houston, TexasAges Up to 65 years - NCT07642856Recruiting
Brain Stimulation With Therapy for Cerebellar Disorders
This study tests a combination of gentle brain stimulation paired with specialized exercises designed to help people with cerebellar conditions—disorders affecting balance, coordination, and movement. The goal is to see if pairing these two approaches together works better than either alone.
Baltimore, MarylandAges 18–75 - NCT07638046RecruitingPhase 2
Mindful Walking and Brain Function in Older Adults
This study looks at how mindful walking—combining walking with focused attention—affects thinking and memory in older adults at risk for dementia. Researchers will track your brain activity and daily movement to see if this approach helps protect brain health.
Columbia, South CarolinaAges 60 years+ - NCT07638462Recruiting
Early mobility recovery program after acute stroke
This study tests whether early movement and physical activity help stroke patients recover better mobility. You'd be in the hospital after a recent stroke, and the team would work with you on safe movement and exercises during your recovery.
Winston-Salem, North CarolinaAges 18 years+ - NCT07644325Recruiting
Comparing Two Biopsy Methods for Carpal Tunnel Amyloidosis
This study compares two small tissue samples taken during carpal tunnel surgery to see which method best detects a protein disease (transthyretin amyloidosis) that can affect nerves and the heart. If you have carpal tunnel syndrome and are having surgery, this research may help doctors diagnose related heart or nerve problems earlier.
MontpellierAges 18 years+ - NCT07646314Recruiting
Physical therapy techniques for piriformis syndrome pain
This study compares two hands-on physical therapy methods to reduce pain from piriformis syndrome, a condition where a muscle in the buttock area pinches a nerve. You'll receive treatment and be asked which technique works better for your pain and movement.
Lahore, Punjab ProvinceAges 25–40 - NCT07641569Recruiting
Dual-Task Training Methods for Parkinson's Disease
This study compares two different training approaches that combine cognitive (thinking) and physical exercises to help improve balance, walking, and daily functioning in people with Parkinson's disease. The goal is to find which method works better for maintaining independence and preventing falls.
Ankara, KeçiörenAges 40 years+ - NCT06685380Recruiting
Cognitive Control During Sleep: Self-Awakening Study
This study looks at how our brains control waking up on purpose during sleep. It may help people who can train themselves to wake up at specific times.
Milan, ItalyAges 18–65 - NCT05734547Recruiting
Support for children after trauma through parent-and-child sessions
This trial offers a structured program for children who have ongoing trauma symptoms after a scary or harmful event, with work involving both the child and a parent/caregiver. It aims to reduce post-trauma stress symptoms and help the child feel safe again.
AskerAges 7–12 - NCT06690073Recruiting
Motor relearning program for stroke recovery
This trial tests a motor relearning program to help people who had a stroke more than six months ago improve their ability to move and walk. It focuses on retraining the brain and body to work together for everyday activities.
Riyadh, Riyadh RegionAges 45–65 - NCT05483816Recruiting
Sensory stimulation trial for nerve pain in people with neuropathy
This study tests a multi-sensory (multiple-sense) stimulation approach to see if it can help people with nerve-related pain in the legs/feet. You must be able to safely take part in MRI-related sessions and answer questions about pain and health history.
Zurich, Canton of ZurichAges 18–80 - NCT05741593Recruiting
Interview study for older adults after ischemic stroke
This study talks with people age 65+ who were hospitalized for an ischemic stroke and are already on blood-thinning medicines to learn about their experiences. The interviews may help improve how pharmacists support patients after stroke.
VilleurbanneAges 65–100 - NCT06446778Recruiting
Pipeline device for brain aneurysms
This trial tests a treatment called Pipeline Embolization (a thin tube placed in the artery) to fix brain aneurysms that haven't ruptured. It might help stop the aneurysm from growing or bursting.
Guangzhou, GuangdongAges 22–75 - NCT06678347Recruiting
Leadership program for healthcare managers
This trial tests a program to help first-line managers in hospitals lead better and support their teams. It may benefit managers and their employees by improving work recovery and well-being.
GothenburgAges 18 years+ - NCT04880356Recruiting
Study of very rare inherited brain diseases over time
This study follows adults over time who have a very rare inherited brain disease, or whose illness seems like it may run in families. The goal is to better understand these conditions and how they progress.
Milan, MilanoAges 18 years+ - NCT06681623Recruiting
Ublituximab in older adults with relapsing MS
This study is testing how safe and effective the medication ublituximab is for older adults (ages 55–80) with relapsing multiple sclerosis. It aims to see if this treatment works well for this age group.
Foxborough, MassachusettsAges 55–80 - NCT03944876RecruitingPhase 3
Botulinum toxin to block a facial nerve for chronic cluster headaches
This trial tests whether injections of botulinum toxin type A can reduce frequent, severe cluster headache attacks by targeting a facial nerve area. It’s for people whose cluster headaches have not responded well—or have caused side effects—to standard preventive treatments.
HamburgAges 18–85 - NCT06543758RecruitingPhase 4
Gait rehab with a wearable robot at home
This trial tests whether using a wearable robotic device at home can improve walking ability in people who have had a stroke. If you have trouble walking due to a stroke, this study may help you regain strength and mobility.
Yongin-si, Gyeonggi-doAges 19–79 - NCT06692569Recruiting
Modified physical therapy for arm and hand recovery after stroke
This study tests a type of physical therapy called modified constraint-induced movement therapy to help improve arm and hand function in people who have had a stroke more than six months ago. You will be encouraged to use your affected arm more often while the stronger arm is gently restricted, which may help retrain your brain and improve movement.
Riyadh, Riyadh RegionAges 45–65 - NCT07630545RecruitingPhase 1
Testing a new drug for Parkinson's disease
This study tests an experimental drug, MTX325, in people with Parkinson's disease. The goal is to see if it is safe and how the body processes it, which may lead to new treatment options.
AdelaideAges 18–75 - NCT07637981RecruitingPhase 2
Safety Study of DX243 for Hearing Loss in Noise
This study tests a new medicine (DX243) to see if it is safe and well-tolerated in people with hearing difficulties, especially trouble hearing speech in noisy environments. The goal is to understand how the body processes this medicine and whether it might help improve hearing.
Liège, LiègeAges 18–75 - NCT07636811RecruitingPhase 2
Mivelsiran for Early Alzheimer's in Down Syndrome
This trial tests a new drug called mivelsiran designed to slow early-stage Alzheimer's disease in adults with Down syndrome. The drug works by targeting amyloid, a protein that builds up in the brain and causes cognitive decline.
Maitland, FloridaAges 40–55 - NCT07633301RecruitingPhase 2
TAK-360 Study for Adults With Narcolepsy Type 1
This study tests a new medication called TAK-360 to help adults with narcolepsy type 1 (a condition that causes extreme daytime sleepiness and sudden muscle weakness called cataplexy) feel more alert during the day. The goal is to see if this treatment is safe and effective for managing narcolepsy symptoms.
Redwood City, CaliforniaAges 18–70 - NCT07637162Enrolling by invitationPhase 3
Safety study of AXS-14 for fibromyalgia
This study continues to monitor the safety of an investigational drug called AXS-14 in people with fibromyalgia who previously participated in another AXS-14 trial. Researchers want to make sure the treatment remains safe over time.
Little Rock, ArkansasAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,941 recruiting neurology studies from the U.S. registry right now, out of 18,432 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.