Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,982 recruiting studies in this area right now.
By phase
- Not applicable7,962
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke844
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California465
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas118
Recruiting studies9,979 total
- NCT03245866Recruiting
Study for bleeding caused by a brain aneurysm rupture
This study is for people admitted with a confirmed brain bleeding caused by a ruptured aneurysm. The goal is to better understand this specific cause of bleeding, which may help improve care for patients with aneurysm-related subarachnoid hemorrhage.
Aarau, Canton of AargauAges Any age - NCT03255928Recruiting
Study blood clot cell activity in people with a heart pump
This study looks at how your blood’s clot-forming cells (platelets) behave when you have a heart pump device placed (short-term or long-term). The results may help doctors better understand complications and how to manage them after implantation.
Milan, MIAges 18–75 - NCT03261089Recruiting
Predicting brain outcome after cardiac arrest, reducing bias
This study looks at how to predict brain recovery after certain types of cardiac arrest. It aims to improve decision-making so people are not misjudged due to “self-fulfilling prophecy.”
San Francisco, CaliforniaAges 18–89 - NCT03264352RecruitingPhase 4
Treatment for slightly high blood pressure in type 2 diabetes
This trial tests an intervention to help adults with type 2 diabetes who have “high-normal” blood pressure (not severely high). If you qualify, you may learn whether this approach improves blood pressure and related health outcomes over time.
Guangzhou, GuangdongAges 45–79 - NCT03264261Recruiting
Therapy to improve walking after stroke by using affected arm
This study tests a walking-focused therapy called constraint induced movement therapy (CI therapy) to improve walking after a stroke. It may help people walk faster and more safely by encouraging more use of the more affected side.
Chicago, IllinoisAges 21–75 - NCT03268668Recruiting
Study brain clot makeup and blood markers after stroke
This study looks at the composition of a stroke blood clot and compares it with blood test results to understand treatment response, stroke cause, and prognosis. It may help doctors better predict outcomes and improve care after ischemic stroke.
BordeauxAges 18 years+ - NCT03269630Recruiting
Pulmonary hypertension biobank for heart-lung blood samples
This study collects and stores health information and possibly blood samples from people being evaluated for pulmonary hypertension or related autoimmune conditions. It helps researchers learn more about these illnesses and may support future studies.
New Orleans, LouisianaAges 18 years+ - NCT03272724Recruiting
French study registry for infective endocarditis patients
This trial is a national hospital registry that collects information from people hospitalized with suspected infective endocarditis (an infection of the heart lining or valves). It may help doctors better classify cases and improve care by analyzing real-world patient data.
Vandœuvre-lès-NancyAges 18 years+ - NCT03277365Recruiting
Share your 23andMe data with a digital genetics study
This study tests a digital platform that uses people’s existing genetic information to support genetic research. If you are an adult and willing to share your 23andMe results from an Apple phone, you can likely participate.
La Jolla, CaliforniaAges 18 years+ - NCT03288220Recruiting
Brain stimulation trial to improve arm movement
This trial studies whether a specific kind of non-painful brain stimulation (TMS) can improve arm and hand movement. It tests this in healthy volunteers and in people recovering from stroke.
Bethesda, MarylandAges 18–120 - NCT03290456Recruiting
Prednisone plus rituximab to help keep ANCA vasculitis in remission
This trial studies whether extending low-dose prednisone alongside rituximab (given as infusions at set times) helps keep microscopic polyangiitis (MPA) or granulomatosis with polyangiitis (GPA) in remission. If you respond to initial treatment, the goal is to reduce the chance of relapse and maintain disease control.
AmiensAges 18 years+ - NCT03291652Recruiting
Imaging study of high-risk brain plaque in stroke
This study uses MRI and ultrasound to look closely at brain artery plaques that may release clots and cause stroke. It aims to better understand which plaque features signal higher “embolus” risk, which could guide future care.
Hong KongAges 30–85 - NCT03293758Recruiting
Study of food and gut bacteria changes over time
This study looks at how your diet affects the mix of gut bacteria over time. It may help researchers understand links between food, microbiome (gut bacteria), and health outcomes.
New York, New YorkAges 40 years+ - NCT03295773Recruiting
Study brain artery narrowing after stroke using 3D imaging
This study follows people after a stroke to better understand how the brain’s artery narrowing changes over time. It uses special 3D scans to see how blood flow and artery structure evolve, which may help future stroke prevention and treatment.
Hong KongAges 18–80 - NCT03297606RecruitingPhase 2
Match your tumor test to a targeted cancer drug
This trial studies whether giving a targeted cancer medicine based on tumor genetic/protein test results can help people with advanced, incurable cancers live longer. You may be eligible if your cancer has a “potentially actionable” change on testing and you meet health and follow-up requirements.
Edmonton, AlbertaAges 18 years+ - NCT03299569Recruiting
Learn how often Tako-tsubo heart weakness happens in Scotland
This study aims to measure how many people in Scotland develop Tako-tsubo cardiomyopathy (a temporary heart condition often triggered by stress or illness). It may help doctors better understand who is affected and plan care in the future.
Aberdeen, ScotlandAges Any age - NCT03298243Recruiting
Sensory training to improve arm control after stroke
This study tests a hands-on sensory training approach that uses signals from one sense to help your brain control your arm and hand after stroke. It may help improve grip and arm steadiness, especially for people who still have mild-to-moderate arm weakness more than 6 months after a stroke.
Milwaukee, WisconsinAges 21 years+ - NCT03308474Recruiting
Myeloma patient registry study for treatment experiences
This trial enrolls people with multiple myeloma who are starting (or have recently started) standard drug treatment, so researchers can collect real-world information about patients’ experiences and outcomes. It may help by improving future care planning and study designs, while adding an extra set of questionnaires to your routine.
Multiple SitesAges 18 years+ - NCT03312556Recruiting
CPAP for high blood pressure when lying down
This trial looks at whether using CPAP (a breathing device) can help control high blood pressure that happens when you lie down, in people with autonomic failure. It’s designed for safety and effectiveness and may improve symptoms and blood pressure control.
Nashville, TennesseeAges 18–85 - NCT03317860Recruiting
Tests VR and brain stimulation for stroke neglect
This study looks at ways to measure and improve “neglect,” when someone has trouble noticing one side after a stroke. It involves specific brain/hand stimulation testing and focuses on people a few months after stroke.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT03318432Recruiting
Stroke recovery research registry for people with ongoing symptoms
This study is a registry that enrolls adults who have had a stroke and still have symptoms. It helps researchers learn about stroke recovery over time and may connect you to future stroke research studies.
San Francisco, CaliforniaAges 18 years+ - NCT03323216Recruiting
Testing heart-related blood markers in people with diabetes and heart failure
This study looks for blood markers that may help explain or predict heart problems in people who have type 2 diabetes and heart failure. To join, you may also need to be having a planned heart procedure where doctors can collect study information.
Aachen, North Rhine-WestphaliaAges 18 years+ - NCT03327961Recruiting
Study of implanted scaffolds with follow-up in adults
This study follows adults who have had at least one scaffold placed to see how they do over time. It also looks at whether people can stick with the required anti-platelet medicines for at least a year, and whether they can be followed for a year.
Agrigento, AgrigentoAges 18 years+ - NCT03347786RecruitingPhase 1/Phase 2
Verapamil to protect the brain after acute stroke
This trial tests whether verapamil, a common blood-pressure/heart medicine, can help protect the brain after an acute ischemic stroke. It may improve recovery outcomes by supporting the brain’s ability to heal, especially early after stroke symptoms begin.
Atlantic City, New JerseyAges 18–80
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,982 recruiting cardiology studies from the U.S. registry right now, out of 15,268 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.