Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT07552389RecruitingPhase 3
Blood Pressure and Diabetes Combination Drug Trial
This study tests whether taking two separate blood pressure medications work as well as taking them combined in one pill for people with high blood pressure and type 2 diabetes. The goal is to find the best, safest way to treat both conditions together.
SeoulAges 19 years+ - NCT07558915RecruitingPhase 1
Testing RO7851624 for Relapsed Multiple Myeloma
This Phase 1 trial tests a new drug called RO7851624 in patients whose multiple myeloma has come back or stopped responding to prior treatments. The goal is to understand how safe and effective this drug is.
Parkville, VictoriaAges 18 years+ - NCT07555938RecruitingPhase 3
New drug combination for previously treated multiple myeloma
This trial tests whether a new drug called cevostamab, combined with two existing myeloma drugs (pomalidomide and dexamethasone), works better than standard treatment for people whose myeloma has returned or stopped responding to prior therapy. You would receive this combination to see if it helps control your disease.
Duarte, CaliforniaAges 18 years+ - NCT07556588Recruiting
Heart transplant study using perfusion technology
This study tests a special machine that helps preserve and evaluate donor hearts before transplant. If you're waiting for a heart transplant, this trial may help doctors find the best donor hearts and improve transplant outcomes.
LeuvenAges 18 years+ - NCT06559475Recruiting
Testing a new aspiration catheter for large vessel stroke
This trial tests a new catheter (Super-Bore 8/7F) to remove blood clots in people having a major stroke caused by a blocked large artery in the brain. The goal is to see if it is safe and effective at restoring blood flow when used within 24 hours of stroke symptoms starting.
Hefei, AnhuiAges 18 years+ - NCT06598930Recruiting
Nurse-led follow-up after mild lung blood clot
This study compares two ways of following up after a non-severe pulmonary embolism: standard medical care alone versus intensive monitoring that includes an advanced practice nurse. The goal is to see if the nurse-led follow-up improves your recovery and quality of life.
DijonAges 18 years+ - NCT06738992RecruitingPhase 4
Early aspirin after mitral valve repair: safety and effectiveness
This study tests whether starting aspirin early after mitral valve repair is safe and effective compared to standard care. It's for adults who have had this heart surgery and have a low risk of bleeding or stroke.
Guangzhou, GuangdongAges 18–85 - NCT05332756Recruiting
Long-term follow-up of moyamoya care and family health
This trial follows people with moyamoya disease who are treated with medication only, and it also looks at first-degree relatives. The goal is to understand long-term outcomes and whether careful conservative care is beneficial over time.
Beijing, Beijing MunicipalityAges 2–60 - NCT06590532Recruiting
Testing a new X-ray system for vascular surgery
This study compares a new automated X-ray system (mobile hybrid room) with the current standard equipment used during vascular surgery. It aims to see if the new system is more effective and cost-efficient for treating narrowed or widened blood vessels in the belly area.
Besançon, BesançonAges 18 years+ - NCT06741332Recruiting
AI software to speed up stroke clot removal referrals
This trial tests whether a special AI software can help doctors speed up the process of referring patients with acute stroke for a procedure that removes a blood clot (thrombectomy). If you have stroke symptoms and a recent CT scan, the AI may help identify if you could benefit from this treatment.
Granollers, BarcelonaAges 18 years+ - NCT05660798Recruiting
Switching from cigarettes to heat-not-burn to protect heart arteries
This study looks at whether switching from regular cigarettes to a tobacco heating product slows buildup of plaque in the heart arteries. You’d be guided through smoking change and monitored using heart scans, to see if artery plaque stays the same or improves.
WarsawAges 18–75 - NCT06527742Recruiting
Body health and recovery during rehabilitation
This study looks at how body composition, frailty, and function change during rehabilitation. It may help understand recovery patterns.
Singapore, SingaporeAges 21 years+ - NCT06714565Recruiting
Can blood pressure and brain oxygen predict falls?
This study looks at how measuring blood pressure and oxygen levels in the brain may help predict falls in older adults. If you have fallen before, your participation could help doctors find better ways to prevent future falls.
AmsterdamAges 65 years+ - NCT06742567RecruitingPhase 3
Apixaban to prevent blood clots after a heart attack
This trial tests whether the blood thinner apixaban can prevent dangerous blood clots from forming in the heart's main pumping chamber after a specific type of heart attack. It is for patients who have severe weakness of the left ventricle and no clot already present.
Karachi, SindhAges 18–75 - NCT04913870RecruitingPhase 4
Tested blood pressure pills for mild to moderate aortic narrowing
This study tests whether angiotensin receptor blocker (ARB) blood pressure medication helps people with mild to moderate aortic stenosis (a narrowing of the heart’s main valve). It looks at safety and whether the treatment offers benefit for your heart and blood flow.
Québec, QuebecAges 20–99 - NCT06663631RecruitingPhase 1
Hibernation-like therapy for stroke recovery after clot removal
This trial tests if a hibernation-like therapy can improve recovery after a stroke caused by a large blood clot in the brain. It is for people who are having a stroke and are scheduled for a procedure to remove the clot.
Linyi, ShandongAges 18–80 - NCT04654650Recruiting
Study of adults with pulmonary hypertension for long-term data
This study follows adults with pulmonary hypertension over the long term and collects information (and possibly samples) to better understand how the condition changes over time. It may help researchers learn what factors affect outcomes, which can improve care in the future.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT06271018Recruiting
Tocilizumab for Aortitis in Giant Cell Arteritis
This trial tests the drug tocilizumab (Actemra) to see if it helps reduce swelling in the aorta in people with giant cell arteritis (GCA) who are newly diagnosed or have had a flare. It may offer a targeted treatment for aortitis without using high-dose steroids.
ParisAges 18 years+ - NCT07551167RecruitingPhase 1
Safety Study of HRS-5765 in Healthy Adults
This is an early-stage safety test of a new experimental drug called HRS-5765 in people without serious health conditions. Researchers want to make sure the drug is safe and understand how your body processes it.
Beijing, Beijing MunicipalityAges 18–65 - NCT07543731Recruiting
Study of how patients stick with cholesterol-lowering injection medications
This study follows people who are starting one of three injectable cholesterol medications (inclisiran, evolocumab, or alirocumab) to see how well they stick with treatment over time. Understanding medication adherence helps doctors and patients find ways to improve long-term health outcomes.
BaselAges 18–99 - NCT07543120RecruitingPhase 2
Extended Safety Study of QCZ484 Blood Pressure Medication
This is a continuation study for people who completed a previous QCZ484 trial and tolerated it well. Researchers will monitor how safe and effective the medication remains with longer-term use for managing high blood pressure.
Garden Grove, CaliforniaAges 18 years+ - NCT07547540RecruitingPhase 1
Study of an investigational drug for heart failure
This study tests an experimental drug called LY3971297 to see if it can help people with chronic heart failure. It aims to find out if the drug is safe and if it improves heart function.
Detroit, MichiganAges 18–65 - NCT06091332RecruitingPhase 2
Sirolimus for brainstem cavernoma bleeding
This trial tests if sirolimus, a medicine that may help reduce abnormal blood vessels, can prevent another brain bleed in people who recently had a bleed from a brainstem cavernoma. You would receive either sirolimus or a placebo to see if it works.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06082284Recruiting
M protein detection study for adult patients
This study is looking for adults at Zhujiang Hospital to test a new, highly sensitive method for detecting a protein called M protein in the blood. It helps doctors understand how common this protein is in different patients.
Guangzhou, GuangdongAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.