Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,982 recruiting studies in this area right now.
By phase
- Not applicable7,962
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke844
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California465
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas118
Recruiting studies9,979 total
- NCT03132129Recruiting
Heart imaging study in adults with type 2 diabetes
This study looks for early, “silent” changes in heart function in adults with type 2 diabetes, even if you feel okay. It uses heart scans and looks for factors that may help explain why these changes happen.
LeicesterAges 50–75 - NCT03135327Recruiting
Eye scans study to compare brain and eye health
This study uses detailed eye imaging to look for patterns that may go along with conditions like Alzheimer’s disease, memory problems, multiple sclerosis, or eye/vascular issues. It may help researchers better understand how eye findings relate to health and disease.
Miami, FloridaAges 18–99 - NCT03139786Recruiting
Heart valve follow-up study for bicuspid aorta patients
This study follows patients who have a bicuspid aortic valve—a heart valve with two leaflets instead of three. Researchers track how this condition changes over time to better understand its long-term effects and help guide future care.
Amiens, PicardieAges 18 years+ - NCT03143361Recruiting
Aortic valve replacement registry for adults needing valve surgery
This study follows adults who are having aortic valve replacement to better understand outcomes across different hospitals in Europe. It may help your care team compare results and improve future treatment planning.
VeronaAges 18 years+ - NCT03142659Recruiting
Heart failure care evaluation for adults at this clinic
This study looks at how people with heart failure are evaluated and managed in the clinic. It mainly involves follow-up care and documenting your treatment plans to improve how care is delivered.
Tel AvivAges 18–120 - NCT03152630Recruiting
Vascular dementia check-up and risk diagnosis study
This study aims to find early ways to diagnose “vascular dementia,” which happens when blood vessel problems affect thinking and memory. It may help by testing how well certain health risk factors and medical information can predict who might be developing it.
TaipeiAges 65 years+ - NCT03153683Recruiting
Brain and blood clot registry for adults having brain blood tests
This study is a registry, meaning it collects information from people having surgery or procedures for problems involving blood vessels in the brain. It may help researchers better understand brain blood conditions and clots by tracking patterns over time.
Lexington, KentuckyAges 18 years+ - NCT03169010Recruiting
Study registry for rare lung artery blood pressure problems
This study collects information from people with rare types of pulmonary hypertension (high blood pressure in the lungs) and from healthy volunteers. It helps researchers better understand these conditions, especially using a special lung-heart test to confirm the diagnosis.
Beijing, Beijing MunicipalityAges Any age - NCT03192774Recruiting
Prospective heart valve treatment registry for TAVI patients
This study is a real-world registry that collects information from people who receive TAVI, a procedure to treat a damaged heart valve. It may help doctors understand outcomes and improve care, even though it isn’t testing a new drug.
Bad SegebergAges 18–100 - NCT03185702Recruiting
Turner syndrome research registry for people with Turner syndrome
This registry study is collecting information from people who have Turner syndrome. It may help researchers better understand the condition and plan future studies that could lead to improved care.
Houston, TexasAges Any age - NCT03186391Recruiting
Exercise testing for leg artery disease symptoms
This study tests how well people with peripheral artery disease can use a treadmill for exercise testing. It may help doctors better understand exercise limits and guide safer care.
RennesAges 1.5 years+ - NCT03195556Recruiting
Test ultrasound contrast to improve blood flow in legs
This study checks whether using a special ultrasound with contrast can improve blood flow in people with peripheral artery disease (PAD). If you have leg circulation problems, it may help doctors measure and potentially enhance how well blood reaches your limb.
Portland, OregonAges 19–99 - NCT03206060RecruitingPhase 2
Lu-177 DOTATATE for hard-to-remove pheochromocytoma or paraganglioma
This trial studies Lu-177 DOTATATE (Lutathera), a targeted radiation medicine, for tumors that cannot be safely removed with surgery. It aims to shrink or control pheochromocytoma/paraganglioma that is showing recent growth and has a specific target signal on a special PET scan.
Bethesda, MarylandAges 18–100 - NCT03201094Recruiting
NMES and whey protein for recovery after aneurysmal brain bleed
This pilot study tests whether a therapy that gently stimulates nerves (NMES) and a whey-protein supplement (HPRO) can improve recovery after an aneurysmal subarachnoid hemorrhage (SAH), a type of bleeding around the brain. Participants are usually treated soon after the bleed and stay in the ICU long enough for the study measures.
Baltimore, MarylandAges 18 years+ - NCT03206814Recruiting
Mobile app coaching to improve high blood pressure control
This trial tests whether a smartphone app with remote care (telecare) can help people with hard-to-control high blood pressure reach better blood pressure numbers. It may help you and your care team monitor progress more closely at home.
Bahía BlancaAges 18–80 - NCT03209414Recruiting
Study of frailty in heart patients receiving heart care
This trial looks at “frailty,” meaning reduced strength and resilience, in older adults with coronary artery disease who are getting heart care. It may help doctors better understand which patients are more at risk and how care decisions could be improved.
Zabrze, Upper SilesiaAges 65 years+ - NCT03209674Recruiting
Registry tracking outcomes after heart and chest surgery
This is a registry that collects information from people who have heart or chest (thoracic) surgery. It may help doctors understand what improves outcomes after surgery, but it usually does not test a new drug.
Neuilly-sur-Seine, Île-de-France RegionAges Any age - NCT03211793RecruitingPhase 1/Phase 2
Cell treatment for painful hand sores in systemic sclerosis
This trial tests a cell-based treatment (mesenchymal stromal cells) to help heal painful finger/toe ulcers in people with systemic sclerosis. It is for ulcers that did not improve after a specific IV medicine called prostacyclins.
UtrechtAges 18 years+ - NCT03211975Recruiting
Understanding the Course of Heart Valve Infections
This study follows patients diagnosed with infectious endocarditis (a serious infection of the heart valve) to better understand how the condition progresses and what factors affect outcomes. Researchers will use imaging tests and surgical information to track your health over time.
Amiens, PicardieAges 18 years+ - NCT03217656Recruiting
Jiaxing birth follow-up study for pregnant families
This study enrolls pregnant women in the Jiaxing area and follows them during pregnancy and after delivery to learn about mothers and babies. If you plan to stay involved through birth and follow-up, this may help researchers understand pregnancy and early childhood outcomes.
Hangzhou, ZhejiangAges Any age - NCT03233087Recruiting
Study to predict outcomes in aortic dissection
This study collects medical information and blood-test timing data to learn how to diagnose aortic dissection sooner and predict outcomes. It may help doctors better plan care for people with suspected or confirmed aortic dissection.
Beijing, Beijing MunicipalityAges 18–80 - NCT03225586Recruiting
Study of health differences in urban and rural communities
This study enrolls consenting adults to understand how health differs between people living in cities versus rural areas. Your participation may help researchers learn what factors influence health over time.
Rosario, Santa Fe ProvinceAges 35–70 - NCT03240965Recruiting
Testing changes in smell and taste after recent stroke
This study looks at how smell and taste may change after a new stroke, especially in the first few days. It may help doctors better understand and monitor symptoms related to eating and swallowing after stroke.
Giessen, HesseAges 18 years+ - NCT03242642Recruiting
Testing a new catheter procedure to replace a leaking mitral valve
This trial studies whether a new catheter-based system can replace a badly leaking mitral valve in people who have symptoms. It may help if you can’t safely get current approved valve treatments or standard surgery.
Birmingham, AlabamaAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,982 recruiting cardiology studies from the U.S. registry right now, out of 15,268 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.