Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT07563153Recruiting
Pacemaker Pacing Strategies for Heart Failure Patients
This study tests whether optimized pacemaker settings can improve heart function and symptoms in heart failure patients who need a pacemaker for a slow heartbeat. The goal is to find the best way to program the pacemaker to help your heart work better.
Seoul, SeoulAges 19 years+ - NCT07563322Recruiting
Nicotinamide Riboside for Combined Pulmonary Hypertension
This study tests whether nicotinamide riboside (a B-vitamin supplement) can help people with combined pulmonary hypertension—a condition where blood pressure in the lungs is too high. The researchers want to understand how this supplement affects the body's energy metabolism and whether it might reduce symptoms and improve heart function.
Nashville, TennesseeAges 18–85 - NCT05839717Recruiting
Testing gene changes in PV or ET and blood clot risk
This study looks at a specific gene mutation in people with polycythemia vera (PV) or essential thrombocythemia (ET) to understand how it may relate to blood clots. It mainly involves collecting blood samples and joining a medical registry, before clot-lowering medicines start.
AngersAges 18 years+ - NCT06735521Recruiting
Heart MRI stress test for Fontan circulation
This study uses a special heart MRI with a medicine that stresses the heart (like exercise) to look at blood flow in people who have had the Fontan surgery. The goal is to better understand how the heart works after this surgery.
StockholmAges 18 years+ - NCT06734221Recruiting
Testing a paclitaxel-coated balloon for leg artery disease
This trial tests a special balloon coated with a drug (paclitaxel) to open blocked leg arteries, aiming to improve blood flow and reduce symptoms like leg pain when walking. It is for people with moderate to severe leg artery disease who have not had prior stents or bypass in the treated area.
Chrzanów, MalopolskaAges 18 years+ - NCT05560724Recruiting
Brain stimulation after stroke to track recovery signals
This study looks at whether brain stimulation and brain scans can help measure recovery after an ischemic stroke. It may help researchers understand who benefits from non-invasive brain stimulation by using brain “signal” markers.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT06209606RecruitingEarly Phase 1
Blood test study for multiple myeloma progression
This study is testing whether a blood test that measures a protein called BCMA can help doctors know if your multiple myeloma is getting worse. You may be able to join if your myeloma has come back or not responded to at least two prior treatments, and you have not taken the drug Ruxolitinib before.
West Hollywood, CaliforniaAges 18 years+ - NCT06368206Recruiting
Testing a fingertip light sensor for blood pressure
This study tests a new way to measure blood pressure by using a light sensor on your fingertip, instead of a traditional arm cuff. It aims to see if this optical method works as well as standard blood pressure checks.
LausanneAges 21–85 - NCT06726811Recruiting
Droperidol and changes in heart electrical activity
This study looks at how a medication called droperidol (given through an IV for nausea or agitation) affects the heart's electrical activity. If you are in the emergency department and need both an ECG and droperidol, researchers will check your heart tracing before and after the medication to see if there are any changes.
Corpus Christi, TexasAges 18 years+ - NCT06727006Recruiting
Rescue stenting and clot-dissolving medicine for severe stroke
This trial tests whether using a stent plus a clot-dissolving drug can improve outcomes for people with a large-vessel stroke who are having a procedure to remove the clot. It is designed for patients who can receive treatment within 24 hours of their first symptoms.
Bergamo, ItalyAges 18 years+ - NCT06737549RecruitingPhase 4
Electroacupuncture and NGF for swallowing problems after stroke
This study tests whether a specific type of electroacupuncture (a gentle needle therapy with mild electrical pulses) plus a nerve growth factor injection can help people who have trouble swallowing after a recent stroke. The goal is to see if this combination improves swallowing function better than standard care.
Hangzhou, ZhejiangAges 18–80 - NCT06377761Recruiting
Qishen granules for heart failure with preserved pumping function
This trial tests a Chinese herbal medicine called Qishen Granules for people with heart failure who still have a normal pumping ability (ejection fraction 50% or higher). It may help reduce symptoms and improve heart function.
Guangzhou, GuangdongAges 18–85 - NCT06738537Recruiting
Choosing treatment for mitral valve prolapse
This study looks at how to involve you in decisions about treating mitral valve prolapse, a condition where a heart valve doesn't close tightly. It aims to find the best way to help you and your doctor choose the right treatment.
Los Angeles, CaliforniaAges 21 years+ - NCT06738615Recruiting
Symptoms and severity of a leaky mitral valve study
This study looks at how symptoms relate to the severity of mitral regurgitation, a leaky heart valve. Researchers want to better understand the link between what you feel and the actual degree of the leak.
Morristown, New JerseyAges 18 years+ - NCT06511245Recruiting
Comparing WEB to other treatments for ruptured brain aneurysms
This trial compares a new device called WEB (a mesh-like implant) with other standard treatments for people who have a ruptured brain aneurysm. The goal is to see if WEB works as well or better than other options.
ReimsAges 18 years+ - NCT05806346Recruiting
TXA dosing for heart surgery patients on bypass
This trial studies whether giving tranexamic acid (TXA) based on patient needs during heart surgery works better than a one-size-fits-all approach. It may help reduce bleeding during surgery, while monitoring for clotting-related side effects.
SeoulAges 19 years+ - NCT06561854RecruitingPhase 3
Comparing multiple myeloma treatment with and without dexamethasone
This trial tests whether adding dexamethasone to an antibody-based combination therapy works better for multiple myeloma that has come back after previous treatments. If you have had 1 to 3 prior therapies and are eligible for one of two standard drug regimens, this study may help find the best approach for you.
ParisAges 18 years+ - NCT07556523RecruitingPhase 4
Recovery quality after heart valve replacement with different sedation
This study compares how well patients recover after a minimally invasive heart valve procedure (TAVR) when given different types of sedation. The goal is to find which sedation approach helps patients feel better and recover faster after the procedure.
Glenview, IllinoisAges 18–90 - NCT07556185Recruiting
Testing a home heart health monitoring app for kids
This study tests whether young people with heart conditions can use a home monitoring app called Medly to track their symptoms and weight. The app may help doctors catch problems earlier and keep kids healthier at home.
Toronto, OntarioAges 8–18 - NCT07557108Recruiting
Nerve Blocks to Improve Recovery After Heart Surgery
This study tests whether special numbing injections around nerves in the chest wall (fascial plane blocks) help patients recover better and have less pain after open-heart surgery. The goal is to see if this technique improves how you feel and function in the days after your operation.
Ordu, AltinorduAges 18–70 - NCT07555977Recruiting
Clot removal methods for acute ischemic stroke
This trial compares two ways of removing a blood clot from a large artery in the brain during an ischemic stroke. It might help you by finding out which method restores blood flow more safely and effectively.
ShanghaiAges 18 years+ - NCT07559006Recruiting
Shoulder Pain After Stroke and Its Effects on Arm Function
This study looks at how shoulder pain affects arm movement, balance, and daily activities in people who've had a stroke. Researchers want to understand the connection between shoulder pain and physical recovery after stroke.
Kütahya, KütahyaAges 18–80 - NCT07556887Recruiting
Using IMPROVE to Choose Carotid Artery Treatment After Stroke
This study tests whether a new tool called IMPROVE helps doctors decide if you need surgery or a stent to clear a narrowed carotid artery (a major neck blood vessel) after a recent stroke or mini-stroke. The goal is to better predict which patients will benefit most from this treatment.
Arnhem, GelderlandAges 18 years+ - NCT07551947Enrolling by invitation
Insulin Resistance and Heart Rhythm Ablation Success
This study examines whether how your body handles insulin (a hormone that controls blood sugar) affects the success of a new ablation procedure called pulsed field ablation, which treats irregular heart rhythms. Researchers want to understand which patients benefit most from this treatment.
TřinecAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.