Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,982 recruiting studies in this area right now.
By phase
- Not applicable7,962
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke844
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California465
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas118
Recruiting studies9,979 total
- NCT03457168Recruiting
Testing treatment for high blood pressure during sleep
This study looks at how to manage high blood pressure specifically during sleep, aiming to lower the risk it can cause over time. It may help you if your blood pressure readings stay high at night even if you’re otherwise able to function normally.
Ourense, OrenseAges 18 years+ - NCT03470246Recruiting
Wearable activity coaching after heart surgery
This study tests a personalized activity program and coaching after heart surgery, using wearable sensors to track movement. It may help you recover more safely and move in a goal-directed way during rehabilitation.
KuopioAges 30–90 - NCT03475173Recruiting
Non-invasive eye scans for healthy and specific retinal problems
This study tests new, non-invasive ways to measure how the retina (the light-sensing part of the eye) is structured and how well it works. It may help researchers better understand certain vision disorders and how to track them, without surgery or injections.
Iowa City, IowaAges 18–99 - NCT03481075Recruiting
Personalized CT modeling to plan safer aneurysm stent repair
This study uses your detailed CT scan to create a personalized computer plan for placing a stent inside your enlarged aorta (an abdominal aortic aneurysm). It may help doctors choose the best stent approach for your anatomy during endovascular repair.
Montreal, QuebecAges Any age - NCT03479580Recruiting
Registry for coronary and small-vessel heart disease in cardiomyopathy
This study enrolls people with certain types of heart muscle diseases to learn how blocked heart arteries and tiny blood vessels affect symptoms and outcomes. It may help researchers better understand these conditions and improve future care.
La TroncheAges 18–100 - NCT03481205Recruiting
Air-transport treatment to protect brain tissue after stroke
This trial studies a protective “conditioning” treatment given during air ambulance transport for people with a suspected large-vessel ischemic stroke. The goal is to reduce further brain injury and preserve more brain tissue while you’re being transported for stroke care.
Iowa City, IowaAges 18–80 - NCT03485040Recruiting
Rehab study for arm weakness after stroke
This study tests a rehabilitation approach to help people recover arm movement after an ischemic or bleeding stroke. You may be able to join if you’re currently an inpatient in the stroke neurology unit and have arm weakness but are medically stable and able to follow simple instructions.
Boston, MassachusettsAges 18–90 - NCT03488732Recruiting
Heart valve disease registry for people needing valve treatment
This study is a registry that collects information about people with severe heart valve problems who are planning to have a valve procedure. It may help doctors better understand your condition and treatment over time.
MünchenAges 18 years+ - NCT03502408Recruiting
CT or MRI blood-flow imaging in strokes treated within 6–24 hours
This study checks how well CT or MRI “blood-flow” scans predict and measure brain injury in people with an acute ischemic stroke who are getting a clot-removing procedure. It may help doctors choose the right people for treatment and evaluate treatment effects using imaging taken soon after hospital arrival.
Hangzhou, ZhejiangAges 18 years+ - NCT03497637Recruiting
Compare two ways to measure artery narrowing during heart procedures
This study compares two pressure-based methods (Vessel-FFR vs standard FFR) to decide how severe a heart artery narrowing is during a coronary angiogram or PCI. It may help patients and doctors choose which narrowings need treatment more accurately.
DresdenAges 18 years+ - NCT03504007Recruiting
Patient registry for people starting blood thinners after a clot
This registry collects information from people who had a clot (venous thromboembolism) and start blood thinners soon after diagnosis. It may help doctors better understand treatment patterns and outcomes after early blood-thinner use.
Rochester, MinnesotaAges 18 years+ - NCT03524222Recruiting
Home hospital care for adults after sudden illness
This trial tests whether certain adults can safely receive hospital-level care at home instead of staying in the hospital, using a home care team. It may help you recover in your own home if your condition fits their plan and you have support at home.
Boston, MassachusettsAges 18 years+ - NCT03536312Recruiting
Surgery versus monitoring for enlarged ascending aorta
This trial compares two ways to treat an enlarged (bigger) ascending aorta: having surgery now versus careful imaging follow-up (surveillance). It may help you and your care team decide which approach lowers the risk of serious problems for aneurysms in a specific size range.
San Francisco, CaliforniaAges 18–79 - NCT03539133Recruiting
Study heart-to-body communication after a heart attack
This study is for people who have recently had a STEMI heart attack. Researchers are looking at how the heart’s injury affects the rest of the body, which may help improve care after this type of emergency.
DüsseldorfAges 18 years+ - NCT03544489Recruiting
Exercise program after ICD implant
This trial studies whether adding a structured exercise program after an ICD implant is safe and helpful for people with certain heart rhythm problems. You may qualify if you can comfortably walk daily and can follow the study schedule for several months.
Seattle, WashingtonAges 18 years+ - NCT03542734Recruiting
Imaging study for thinking and brain changes in older adults
This study looks at brain scans and eye/eye-nerve findings to understand why thinking can change with aging. It may help researchers connect eye and brain changes, which could guide future ways to prevent or detect dementia early.
HangzhouAges 40 years+ - NCT03546374Recruiting
Stop a common heart rhythm with surgery add-on therapy
This study looks at whether an added heart device approach around the time of planned open-heart surgery can help treat non-paroxysmal atrial fibrillation (AF), a long-lasting irregular heartbeat. It may help lower ongoing AF burden in people who also need non-emergency heart surgery.
Palo Alto, CaliforniaAges 18 years+ - NCT03546309Recruiting
Testing RIC to help children with moyamoya after surgery
This trial studies whether a treatment called RIC (remote ischemic conditioning) is safe and helpful for children with moyamoya disease who undergo revascularization surgery. It aims to improve outcomes after surgery and reduce risk, while carefully tracking safety.
Beijing, Beijing MunicipalityAges Up to 18 years - NCT03546231Recruiting
Understanding Tricuspid Valve Leakage: A Research Study
This study looks at people with moderate or severe leakage in the tricuspid valve (a valve in the right side of the heart) to understand how the condition develops and what outcomes patients experience. Researchers want to learn more about this condition so they can improve care.
AmiensAges 1.5 years+ - NCT03547856Recruiting
Registry study for blood pressure control in adults
This study collects health information to understand how well people with high blood pressure (who take blood pressure medicines) reach their blood pressure targets. It may help improve future guidance on blood pressure monitoring and control.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT03549559Recruiting
Heart imaging study in healthy people and specific conditions
This study uses heart imaging to look at changes in the heart muscle. It includes healthy volunteers and people with diabetes or aortic stenosis, to understand differences seen on scans.
Boston, MassachusettsAges 18–85 - NCT03552926Recruiting
Biobank and scan database for recent small stroke patients
This study builds a database and collection (a biobank) from people who recently had a small stroke affecting deep brain areas. It may help researchers better understand small stroke patterns and support future care through better brain imaging and follow-up.
ParisAges 18 years+ - NCT03559114RecruitingPhase 3
Preventing blood clots after severe brain injury
This trial tests whether taking an anti–blood clot medicine (dalteparin) and using leg compression can reduce dangerous blood clots after a severe traumatic brain injury. It may help lower the chance of clots forming when people are immobile and at higher risk.
Calgary, AlbertaAges 18 years+ - NCT03559569Recruiting
Study blood changes in people with circulatory shock
This study looks at how blood vessel and white blood cell aging changes during circulatory shock. Your participation may help doctors better understand what’s happening in the body during shock.
StrasbourgAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,982 recruiting cardiology studies from the U.S. registry right now, out of 15,268 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.