Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT05209776Recruiting
Studying heart inflammation patterns in specific heart rhythm conditions
This study compares inflammation-related signals in people with arrhythmogenic right ventricular cardiomyopathy versus people having certain heart procedures for non-cancer, non-inflammatory reasons. It may help researchers better understand what drives abnormal heart rhythms in this condition.
ToulouseAges 18–99 - NCT05212792Recruiting
Study genes after COVID vaccine side effects
This study looks at genetic information to better understand why some people develop serious side effects after a COVID-19 vaccine, such as GBS, blood clotting with low platelets (VITT/TTS), or heart inflammation (myocarditis/pericarditis). Your information may help researchers learn who is at higher risk and improve future safety.
Vancouver, British ColumbiaAges 5–99 - NCT05213429Recruiting
Coronary artery ectasia registry for people getting heart angiograms
This study is a registry (a structured way of collecting health information) for people suspected of coronary artery disease who are having an elective heart angiogram. It helps researchers better understand coronary artery ectasia and how it shows up in everyday patients.
AmmanAges 18 years+ - NCT05213598Recruiting
Biomarker study for liver disease after Fontan surgery
This study looks for blood and/or test markers that can better show how severe liver disease is in people who had the Fontan heart procedure. It also involves medical imaging and/or a liver biopsy or related procedures to help evaluate those markers.
Bethesda, MarylandAges 18–100 - NCT05213676RecruitingPhase 4
Testing stopping inhaled nitric oxide in newborns with CDH
This trial studies whether stopping inhaled nitric oxide (a breathing medicine) can be safely used in newborns with congenital diaphragmatic hernia (CDH). It may help the team decide the best way to use this medicine during early newborn care.
Birmingham, AlabamaAges birth–1 month - NCT05215587Recruiting
Testing treatment for uncomplicated type B aortic tear
This trial studies which treatment is best for people with a recent, “uncomplicated” type B aortic dissection (a tear in the aorta). It may help doctors choose safer care for patients whose dissection has not yet caused major complications.
AalborgAges 18 years+ - NCT05216042Recruiting
Study of genetics and heart/metabolic health in adults
This study looks at how genetic markers (DNA) relate to heart health and “metabolic” health (how your body manages sugar and fat). You may be asked to provide genetic samples and follow study health checks and protocols to help researchers understand who is at higher risk.
Birmingham, AlabamaAges 18 years+ - NCT05216666Recruiting
Surgery type and leftover limping after hip replacement
This study looks at whether the kind of hip surgery approach affects how much limping remains after a total hip replacement. You may benefit by helping researchers find the approach that leads to better walking after surgery.
MölndalAges 40–80 - NCT05218278Recruiting
Nerve and brain signals after out-of-hospital cardiac arrest
This study looks at measurements taken after someone survives an out-of-hospital cardiac arrest to see if the results can predict outcomes. It may help doctors understand which patients are likely to do better and guide care in the ICU.
MariborAges 18 years+ - NCT05219721RecruitingPhase 1
CAR T-cell study for relapsed multiple myeloma with GPRC5D
This Phase 1 trial tests a CAR T-cell treatment made to target a protein called GPRC5D on myeloma cells. It may help patients whose multiple myeloma or plasma cell leukemia has come back or stopped responding to prior treatments.
Wuhan, HubeiAges 18–75 - NCT05225311Recruiting
Registry for pregnancies with Ebstein and tricuspid valve issues
This registry collects information about pregnancies where the baby is diagnosed with Ebstein anomaly and/or tricuspid valve dysplasia. It helps doctors learn how these heart conditions affect pregnancies and outcomes, and can support better future care.
Toronto, OntarioAges Any age - NCT05227053Recruiting
Cryoablation study for paroxysmal atrial fibrillation after approval
This study looks at outcomes after a specific heart procedure called pulmonary vein isolation done with a cryoablation catheter. It is for adults with symptomatic “paroxysmal” atrial fibrillation who are planning this exact procedure.
Anchorage, AlaskaAges 18 years+ - NCT05228340Recruiting
Treating toe ulcers by releasing tight tendons to prevent recurrence
This study looks at whether a minor procedure on a toe (called a flexor tenotomy) can reduce the chance that diabetic toe ulcers come back. It is for adults with diabetes who have nerve damage in the feet and have had toe ulcers before.
Amsterdam, North HollandAges 18 years+ - NCT05230745Recruiting
Test device for heart failure safety and how well it works
This trial studies whether the ContraBand device can be safely placed in people with long-term, symptomatic heart failure and reduced heart pumping. It also looks at whether the approach is practical and tolerable, and gathers early safety information.
AalstAges 18–85 - NCT05230446Recruiting
Testing full stent treatment for heart artery blockages
This study looks at how well doctors can treat multiple blocked heart arteries using a specific drug-eluting stent, aiming to fully open them. It may help patients whose blockage pattern fits the study, but it does not include certain high-risk or special cases.
Rotterdam, South HollandAges 18–85 - NCT05230784Recruiting
Air purifier study for people with heart failure
This trial tests whether using air purifiers can help people with heart failure breathe better and feel better. It enrolls adults with recent heart failure and specific heart and lung conditions, while avoiding people with certain severe breathing problems or recent heart device treatment.
Thiruvananthapuram, KeralaAges 18 years+ - NCT05230914Recruiting
Choosing the best scan for stroke clot removal
This trial compares different scan choices to help doctors decide the best approach for removing a stroke clot. It aims to improve outcomes after emergency stroke treatment by using the right imaging information.
Wuhu, AnhuiAges 18 years+ - NCT05231629RecruitingPhase 2
MRD-guided step-by-step treatment for multiple myeloma
This Phase 2 study tests a treatment plan for newly diagnosed multiple myeloma that changes based on MRD results. MRD is a very sensitive lab test that looks for tiny amounts of remaining cancer, which may help tailor therapy to work better and potentially avoid overtreatment.
Birmingham, AlabamaAges 18 years+ - NCT05232240Recruiting
Study blood pressure swings after stroke or TIA
This trial studies changes (“swings”) in blood pressure in people who recently had an ischemic stroke or a TIA. It may help doctors understand how blood pressure fluctuations affect recovery, even when you do not have known hypertension.
Beijing, BJAges 18 years+ - NCT05238610Recruiting
Registry for older adults with stroke of unclear cause and PFO
This study follows adults over 60 who had a stroke where the cause is unclear, and where a heart opening (PFO) may have contributed. It mainly collects information to better understand this stroke pattern and how these patients do over time.
SeoulAges 60 years+ - NCT05234892Recruiting
Tracking outcomes of an aortic stent graft in Italy
This study is a registry that follows people with an abdominal aortic aneurysm who are getting an Endologix Alto stent graft as planned care. It helps doctors understand how well the device works and how safely people do over time.
RomeAges 18 years+ - NCT05234788Recruiting
Radial-access kidney nerve procedure for hard-to-control high blood pressure
This trial tests a procedure that uses a catheter through the wrist or thigh to quiet overactive nerves in the kidney artery. It aims to lower blood pressure in people whose high blood pressure stays uncontrolled despite using multiple blood pressure medicines.
BordeauxAges 18–75 - NCT05235555Recruiting
TAVI registry for people with severe aortic valve disease
This registry follows people with severe aortic valve narrowing (and sometimes a worn-out valve) who are considered good candidates for TAVI, a valve-replacement procedure. It helps doctors better understand outcomes and care over time.
NaplesAges 55–100 - NCT05235464Recruiting
Testing a high-protein diet for heart plaque risk
This study checks whether eating more protein affects atherosclerosis, which is plaque buildup in artery walls. It may help researchers understand if a high-protein approach changes health markers linked to heart disease.
Columbia, MissouriAges 45–75
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.