Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT07370103Recruiting
Predicting low blood pressure in liver disease patients after anesthesia
This study uses an ultrasound to measure blood flow in the neck's main artery to see if it can predict a dangerous drop in blood pressure after you are put to sleep for surgery. It is for adult patients with chronic liver disease who are having planned surgery.
CairoAges 18 years+ - NCT07364175Recruiting
Weight loss drug study for young adults with high blood pressure
This trial tests if the weight loss medication tirzepatide can help young adults (18–40) with obesity and high blood pressure lower their blood pressure. It compares standard care to weight loss with tirzepatide.
Cambridge, CambridgeshireAges 18–40 - NCT07369765Recruiting
Balloon vs stent for blocked arteries
This trial compares two procedures to open completely blocked coronary arteries: a drug-coated balloon or a drug-eluting stent. It may help patients with a single, medium-length blockage in a large enough artery.
IstanbulAges Any age - NCT07363525Recruiting
Early experience with Tigertriever for stroke clot removal
This study looks at the early experience using the Tigertriever device to remove blood clots from large arteries in the brain. It may help researchers understand how well the device works in real-life practice for people having a stroke.
Detroit, MichiganAges 18 years+ - NCT07363343Recruiting
Blood pressure medication study for new mothers after birth
This study tests two different drug combinations to see which works better for new mothers with postpartum high blood pressure that needs more than one medication.
Cleveland, OhioAges 18 years+ - NCT07367841Enrolling by invitation
Heart failure screening pilot for at-risk adults
This study tests a new way to find people who might develop heart failure early, using electronic health records. If you are at risk, screening could help start care sooner and prevent serious problems.
Leeds, West YorkshireAges 40 years+ - NCT07365150Recruiting
Tranexamic acid for brain bleeding
This study tests whether the drug tranexamic acid can help stop bleeding in the brain when given early. It is for people with a spontaneous brain bleed who are awake and can be treated within 6 hours.
Hong KongAges 18 years+ - NCT07367893Recruiting
Exercise echocardiogram registry for heart disease
This study is creating a registry (a database) of patients who have an exercise echocardiogram, which is a stress test that uses ultrasound to look at your heart during exercise. It aims to better understand and diagnose different types of heart disease.
Yongin, Gyeonggi-doAges 18 years+ - NCT07366671Recruiting
Testing a new wire for heart valve replacement safety
This trial tests a special wire to monitor heart function during a less invasive valve replacement procedure (TAVI). It aims to improve safety and understanding of the heart's response during the procedure.
Eindhoven, North BrabantAges 50 years+ - NCT07365501Enrolling by invitation
Blood pressure cuff therapy for heart failure patients
This trial tests if a simple, non-invasive blood pressure cuff procedure can improve blood vessel health in people with possible heart failure. It is an early, single-session study to see how the body responds.
Cuenca, CuencaAges 18 years+ - NCT07363980Enrolling by invitation
Heart CT Study for Rheumatoid Arthritis Patients
This study uses a special heart CT scan to look for early signs of heart disease in people with rheumatoid arthritis. It may help find problems before symptoms start.
AarhusAges 50–75 - NCT07367633Recruiting
Head position after clot removal for stroke
This trial tests whether keeping the head of the bed flat or elevated after a mechanical clot-removal procedure affects recovery. It may help determine the best position to improve outcomes after a stroke caused by a large blockage in a brain artery.
Greater Sudbury, OntarioAges 18 years+ - NCT07368062Recruiting
Mental health after a heart rhythm drug in the ICU
This study looks at the long-term mental health of people who received a drug called dexmedetomidine during an electrical storm (a dangerous heart rhythm) in the ICU.
Ottawa, OntarioAges Any age - NCT07370467Recruiting
MRI study for mitral & tricuspid valve repair
This study uses MRI scans to take detailed pictures of the heart before and after a valve repair procedure. It helps doctors better understand how these new, less invasive treatments affect heart function.
Milan, MilanAges 18 years+ - NCT07361783Recruiting
Heparin before hospital for heart attack
This trial tests whether giving a blood thinner (heparin) early, before you get to the hospital for a heart attack procedure, can improve outcomes. It is for people having a specific type of heart attack (STEMI) who will receive a balloon angioplasty within 2 hours.
Wuhan, HubeiAges 18 years+ - NCT07369999RecruitingPhase 3
Butylphthalide plus tenecteplase for mild disabling stroke
This trial tests whether adding butylphthalide (a drug that improves blood flow) to the standard clot-busting medicine tenecteplase can help people with mild but disabling strokes recover better. If you have had a mild stroke within the last 4.5 hours and are 18–80, this study might be an option for you.
Changsha, HunanAges 18–80 - NCT07362446RecruitingPhase 2
Study of a heart drug for first-time heart attack patients
This trial tests a new drug given shortly after a first heart attack to see if it can reduce heart damage when blood flow is restored. It is for patients having a specific type of heart attack (STEMI) and getting a procedure to open the blocked artery within 6 hours of symptoms starting.
Kingswood, New South WalesAges 40–75 - NCT07369895RecruitingPhase 1
A new cell therapy for relapsed or refractory multiple myeloma
This trial tests a new cell therapy (O&D-001) for multiple myeloma that has returned or not responded to previous treatments. It targets specific markers on myeloma cells (BCMA or GPRC5D) and aims to shrink the cancer.
Guangzhou, GuangdongAges 18–75 - NCT07363161Recruiting
Drug-coated balloon vs. stent for high-risk heart disease
This trial compares two treatments for people with complex coronary artery disease who have high-risk conditions or complicated blockages: a drug-coated balloon (DCB) versus a drug-eluting stent (DES). Both are ways to open up narrowed arteries and keep them open without surgery.
HomburgAges 18 years+ - NCT07367100Recruiting
Testing a new clot-removal catheter for stroke
This study tests a special catheter (a thin tube) designed to remove blood clots from large arteries in the brain during a stroke. The goal is to see if it is safe and effective at restoring blood flow.
EdegemAges 18–90 - NCT07364630Recruiting
Placental membrane trial for diabetic and venous leg ulcers
This study tests whether a special wound dressing made from human placental membrane can help heal diabetic foot ulcers or venous leg ulcers that did not close with standard care. It is for people who were in the BIOCAMP trial and whose ulcer remained open after 12 weeks of standard treatment.
Philidelphia, PennsylvaniaAges 18 years+ - NCT07368933Recruiting
A drug-coated balloon for heart artery blockages
This trial tests a balloon coated with two drugs to treat narrowed or re-narrowed arteries in the heart. It may help people with chest pain or recent mild heart attacks who need a procedure to open a blockage.
BarcelonaAges 18 years+ - NCT07368608RecruitingPhase 1/Phase 2
Testing a new drug for high blood pressure and cholesterol
This study tests a new medicine called BEBT-701 for people with mild to moderate high blood pressure and high cholesterol. The goal is to see if it can lower both blood pressure and LDL ('bad') cholesterol safely.
Changsha, HunanAges 18–60 - NCT07362303Recruiting
Neuralert stroke monitor study for high-risk patients
This trial tests a device that monitors for stroke in adults who are at high risk after certain heart or blood vessel procedures. It could help detect a stroke early so you get treated faster.
Philadelphia, PennsylvaniaAges 22 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.