Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT04974151RecruitingPhase 4
Prevention trial for stroke risk in people with high blood pressure
This trial tests an approach to prevent first-time stroke and heart problems in people with high blood pressure who also have a specific genetic test result (MTHFR 677 TT). It may help by lowering risk before a first stroke happens.
Bengbu, AnhuiAges 45–74 - NCT06843616Recruiting
Study of a disposable brain clot removal scope for bleeding stroke
This study tests a new disposable tube with a camera (endoscope) that doctors use to remove a blood clot from the brain after a bleeding stroke. It is designed for people who are stable enough for surgery and whose bleed is in a part of the brain that is reachable with this tool.
Guiyang, GuizhouAges 18–80 - NCT04974138RecruitingPhase 4
Preventing first stroke in people with high-risk blood pressure
This trial tests whether a study medicine regimen can help prevent a first stroke in people with hard-to-control “high homocysteine” risk factors linked to a specific gene type. You may qualify if you have certain blood pressure levels, a specific MTHFR gene result, and related blood test findings.
Bengbu, AnhuiAges 45–74 - NCT05874206Recruiting
Branch stent graft for fixing aorta problems in the chest
This trial tests whether a “branch” stent graft can safely repair certain problems in the descending aorta (the big blood vessel in the chest). It may help by sealing the problem while keeping blood flow to an important branch vessel in the left upper chest area.
ZurichAges 18 years+ - NCT06387225Recruiting
Study on brain recovery after cardiac arrest
This study is trying to find better ways to predict recovery in people who had a cardiac arrest outside the hospital and are still unconscious in the intensive care unit. It may help doctors give more accurate information to families.
La Roche-sur-YonAges 18 years+ - NCT06842446Recruiting
Fast detection of blood clots using machine learning
This trial tests whether a machine learning algorithm can quickly detect deep vein thrombosis (blood clots) in people coming to the emergency room. It could help speed up diagnosis and treatment.
SarpsborgAges 18 years+ - NCT06846905Recruiting
Cost and effects of raising the dose of myeloma drugs at home vs. hospital
This study compares whether raising the dose of your current bispecific antibody is more cost-effective when done as an outpatient (day hospital) or as an inpatient. It aims to find the best way to manage your treatment safely.
ToulouseAges 18 years+ - NCT03206814Recruiting
Mobile app coaching to improve high blood pressure control
This trial tests whether a smartphone app with remote care (telecare) can help people with hard-to-control high blood pressure reach better blood pressure numbers. It may help you and your care team monitor progress more closely at home.
Bahía BlancaAges 18–80 - NCT05260125RecruitingPhase 4
Ultrasound-guided shoulder nerve block for stroke pain
This trial compares two ways to deliver a shoulder nerve block to relieve long-lasting shoulder pain after stroke: one guided by ultrasound and one without. It may help if your stroke-related shoulder pain has lasted at least a few months and you may benefit from a targeted pain-relief injection.
BoluAges 25–75 - NCT06068036Recruiting
Telehealth program to boost physical activity after stroke
This study tests whether a telehealth program with a wearable activity tracker can help people who have had a stroke become more active. It's designed for those who are ready to start moving more with their doctor's okay.
Belo Horizonte, Minas GeraisAges 18 years+ - NCT06062017Recruiting
Potassium, hydration, and heart health in young adults
This study looks at how potassium and hydration affect heart and kidney health in healthy young adults. It may help you understand your own health and contribute to new knowledge about preventing disease.
Auburn, AlabamaAges 18–30 - NCT06224660RecruitingPhase 1
Gene therapy for heart problems in Duchenne muscular dystrophy
This trial tests an experimental therapy for heart weakness caused by Duchenne muscular dystrophy. It aims to improve how heart cells handle calcium to protect heart function.
Kansas City, KansasAges 18 years+ - NCT06409754Recruiting
Brain-computer interface for arm recovery after stroke
This trial tests a brain-computer interface system that helps move your arm using electrical stimulation. It is for people who have had a stroke at least 6 months ago and have lasting weakness in one arm.
Mexico City, Mexico CityAges 18 years+ - NCT07360925Recruiting
Fat around heart arteries in transplant patients
This study looks at a type of fat around the heart's arteries in people who need a heart transplant. It may help doctors understand how fat affects heart disease.
PragueAges 30–90 - NCT06652425Recruiting
How cold affects the heart and blood vessels
This study looks at how brief cold exposure affects the heart and blood vessels in healthy adults. It may help us understand the body's response to cold and its potential health impacts.
Shanghai, Shanghai MunicipalityAges 18–30 - NCT07361445Recruiting
Study of a device to help access the heart during ablation
This trial tests a new device to help doctors safely enter the left side of your heart during a procedure called ablation. If you are already scheduled for an ablation or a combined ablation and left atrial appendage closure, this study may be an option.
Jonesboro, ArkansasAges 18 years+ - NCT07352800RecruitingPhase 2
Study of APAC for peripheral artery disease and severe leg ischemia
This trial tests a new drug called APAC to see if it safely prevents blood clots and improves blood flow in people with narrowed leg arteries. It may help those with severe symptoms like pain at rest or non-healing wounds, or those with claudication (leg pain when walking).
HelsinkiAges Up to 85 years - NCT07357285Recruiting
Stroke treatment trial for smaller vessel blockages
This trial tests a new catheter device to remove blood clots from smaller brain arteries in people having a stroke. It aims to see if the device is safe and effective for patients treated within 24 hours of symptoms starting.
BonnAges 18 years+ - NCT07361289Recruiting
Mavacamten for obstructive hypertrophic cardiomyopathy in China
This study looks at how well mavacamten works in real life for adults with obstructive hypertrophic cardiomyopathy, a condition where the heart muscle is thickened and blocks blood flow. It may help improve symptoms like shortness of breath or chest pain.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07357428Recruiting
Brain-computer implant study for severe paralysis or speech loss
This study tests a brain-computer implant that might help people with severe paralysis or speech loss control a computer with their thoughts. It is for people who have trouble moving and speaking due to a progressive disease or injury.
Sacramento, CaliforniaAges 22–75 - NCT07358078Recruiting
Long-term study of ATTR-CM patients on vutrisiran or other approved therapies
This study observes people with ATTR-CM (a heart condition caused by a protein called transthyretin) who are starting treatment with vutrisiran or another approved therapy. It aims to understand how the disease progresses and how treatments work in real life.
Tucson, ArizonaAges 18 years+ - NCT07359768Recruiting
Testing a noninvasive device for heart disease risk
This trial uses a noninvasive device to examine small blood vessels in people at high risk for heart disease. It may help doctors better understand who needs preventive care.
Stockholm, DanderydAges Any age - NCT07361276Recruiting
Observational study on high blood pressure treatment in public clinics
This study looks at how doctors treat high blood pressure in public health clinics. By reviewing medical records, researchers hope to understand what treatments are used and how well they work.
FlorianópolisAges 18 years+ - NCT07360158Recruiting
Studying a new implantable heart device (ICD) for heart patients
This study is testing a new type of implantable cardioverter-defibrillator (ICD) or cardiac resynchronization therapy defibrillator (CRT-D) called the CorSky Family. The goal is to see how well it works for people who need a device to help their heart pump properly and prevent dangerous rhythms.
Graz, StyriaAges 18–99
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.