Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT05691244RecruitingPhase 3
Tested drug for acute ischemic stroke within 24 hours
This Phase 3 trial studies sovateltide (and a placebo) in adults with an ischemic stroke, aiming to improve safety and outcomes. It focuses on people who can start treatment quickly after stroke symptoms begin and who do not have bleeding in the brain on imaging.
Tucson, ArizonaAges 18–80 - NCT05692882Recruiting
Registry for stent treatment in narrowed brain arteries in China
This study records outcomes for people with significant narrowing in brain arteries who have treatment using a drug-eluting stent. It may help doctors understand how well this approach works and what risks or benefits to expect.
ChenzhouAges 18–85 - NCT05692778Recruiting
Care program for people with diabetes and foot problems
This trial is testing an improved care approach for people with diabetes who have foot complications, delivered through primary care. It may help by organizing care more effectively and supporting better diabetes and foot management.
GothenburgAges 18 years+ - NCT05693857Recruiting
Understanding heart risk from test results and questionnaires
This study looks at how well questionnaires and cholesterol test results match a person’s future heart risk. It may help researchers improve how doctors spot who is at higher risk and who can benefit from prevention.
ShatinAges 40–90 - NCT05694572Recruiting
Device follow-up for certain MicroPort CRM heart implants
This study checks how well specific MicroPort CRM heart devices and leads work in real life over time. If you already have one of these FDA/market-approved implants and can be followed yearly, the study helps the company monitor safety and performance.
LisbonAges 18–90 - NCT05695508RecruitingPhase 2
Tested treatment for multiple myeloma after standard care
This Phase 2 study tests a study treatment in adults with multiple myeloma that needs treatment. It may help by trying to improve disease control after you’ve had (or are scheduled to have) standard therapy like chemotherapy and stem cell transplant for some people.
BerlinAges 18–70 - NCT05696522Recruiting
Radiation to treat hard-to-control dangerous heart rhythm
This trial tests a focused type of radiation to treat ventricular tachycardia (VT) that keeps coming back despite other treatments. It may help people who cannot (or do not want to) have the usual catheter procedure to fix the rhythm.
LondonAges 18–85 - NCT05696652Recruiting
Exercise training study for people with heart failure
This study looks for blood and other markers that can explain how people with heart failure respond to exercise training. It may help researchers better tailor exercise or treatment plans for heart failure in the future.
Stanford, CaliforniaAges 18–89 - NCT05697562Recruiting
Embolization treatment for hemorrhoid bleeding
This trial studies a procedure that blocks blood flow to bleeding hemorrhoids (called superior rectal arterial embolization). It may help people with hemorrhoid bleeding who are being considered for treatment, especially when bleeding is significant.
JetteAges 18 years+ - NCT05697575Recruiting
Staphylokinase during stroke blood-flow treatment
This trial studies using a medication called non-immunogenic staphylokinase as part of standard clot-busting treatment for an acute ischemic stroke. It may help clinicians improve blood flow after the stroke using an approach designed to be less likely to trigger immune reactions.
Saint PetersburgAges 18–85 - NCT05698628Recruiting
Timing strategies to protect legs during peripheral ECMO
This trial studies whether an “early” or more “conservative” approach to improving blood flow to the leg can prevent limb damage during a type of heart-lung machine called peripheral VA-ECMO. It may help reduce the risk of poor leg blood flow (ischemia) in people with severe heart failure-related shock.
SeoulAges 19 years+ - NCT05698277Recruiting
Ultrasound to track baby heart function in heart disease
This study uses automated ultrasound measurements to track how a baby’s heart is working during pregnancy. It compares babies who have a specific congenital heart problem with babies without it, to understand what ultrasound can detect.
Sydney, New South WalesAges 18 years+ - NCT05698901Recruiting
Testing heart blood tests and scans to monitor Fabry disease
This study checks whether certain heart-related blood tests and heart scans can help monitor people with Fabry disease. It may be useful for both people who have never received enzyme replacement therapy and those who have.
TaipeiAges 18 years+ - NCT05699629Recruiting
Study of people with coronary heart disease or chest pain
This trial follows people who have coronary heart disease or ongoing chest pain that needs a heart scan called coronary angiography. It also includes healthy volunteers for comparison, to help researchers understand risk factors and outcomes over time.
Jinan, ShandongAges 18 years+ - NCT05700877RecruitingPhase 4
Screening and treatment for silent heart artery disease in type 2 diabetes
This trial tests a screening and intervention approach for “silent” coronary artery disease (heart artery narrowing without major symptoms) in people with type 2 diabetes. It may help prevent future heart problems by finding higher-risk cases early and starting the right treatment plan.
OdenseAges 55–75 - NCT05701293Recruiting
RenZan stent check for leg artery narrowing
This trial follows how well the RenZan stent works and how safe it is for people with blocked or badly narrowed thigh-to-knee leg arteries. It may help by improving blood flow and adding careful monitoring to see how outcomes compare over time.
SienaAges 18 years+ - NCT05701358Recruiting
Guiding heart stent decisions to fully treat blocked arteries after a heart attack
This trial compares two ways doctors decide which additional blocked heart arteries to treat with stents soon after a heart attack. It may help patients avoid later heart problems by testing a “complete revascularization” strategy planned after the initial culprit artery was treated.
Los Angeles, CaliforniaAges 18 years+ - NCT05702203Recruiting
Music therapy for newborns with congenital heart disease
This trial tests whether creative music therapy can help newborn babies who have congenital heart disease (CHD) while they are in intensive care. It focuses on babies who are otherwise very young and in the NICU or PICU, regardless of CHD severity.
ZurichAges 1 minute–4 weeks - NCT05702476Recruiting
Non-invasive 3D scan study for Marfan face features
This study uses a non-invasive 3D scan to better measure facial features in people with Marfan syndrome. It may help researchers describe face differences more accurately, without needles or surgery.
San Donato Milanese, LombardyAges Any age - NCT05703126Recruiting
Blood vessel and heart strength tests in AML patients
This study looks at how well your blood vessels and heart pumping ability work in people with acute myeloid leukemia (AML) receiving certain chemotherapy. It may help doctors better understand heart risk during treatment and tailor monitoring to you.
Samara, Samara OblastAges 18–65 - NCT05703386Recruiting
Study MRI changes in small-vessel stroke disease
This study looks at how “small-vessel” changes in the brain develop after an ischemic stroke, using repeated MRI scans. It may help researchers better understand what causes these changes and how to track them over time.
Baltimore, MarylandAges 18 years+ - NCT05704296Recruiting
Two bypass techniques using leg vein and chest artery
This study compares two ways of using a leg vein and an artery from your chest during coronary artery bypass surgery. It may help doctors learn which approach works best for making the new blood pathways to your heart.
SeoulAges 19 years+ - NCT05706194Recruiting
Early brain prognosis test after out-of-hospital cardiac arrest
This trial studies how to predict brain recovery early after a non-traumatic out-of-hospital cardiac arrest. The goal is to help clinicians estimate outcome sooner, which may improve decision-making during intensive care.
HelsinkiAges 18–100 - NCT05706766Recruiting
Exercise coaching before stem cell transplant for multiple myeloma
This trial studies whether a structured exercise program before an autologous (your own cells) stem cell transplant can improve health and fitness in people with multiple myeloma. The goal is to safely prepare your body for transplant, and the study includes fitness testing and ongoing exercise training.
Boston, MassachusettsAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.