Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,626 recruiting studies in this area right now.
By phase
- Not applicable7,647
- Phase 4471
- Phase 2470
- Phase 3439
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke798
- Heart Failure538
- Hypertension390
- Cardiovascular Diseases374
- Coronary Artery Disease361
- Multiple Myeloma328
- Atrial Fibrillation258
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke138
- Pulmonary Hypertension105
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Acute Coronary Syndrome74
- Obesity74
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine57
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona183
- Massachusetts174
- New York165
- Florida141
- Texas122
- Maryland119
- Minnesota118
- Illinois111
Recruiting studies9,626 total
- NCT05711173Recruiting
Study blood clot triggers and immune cell changes in clot patients
This study looks at how certain blood cell changes and immune system activity may relate to blood clots in specific veins or lungs. It may help researchers understand why clots happen “without a clear cause” and how to better predict risk.
BordeauxAges 6–50 - NCT06461962Recruiting
Peer support for meth-related heart screening
This study tests whether a peer support program can help people who use methamphetamine get screened for early heart damage. It aims to connect you with care if screening shows possible heart strain.
Portland, OregonAges 18 years+ - NCT06706791RecruitingPhase 4
Empagliflozin for heart failure & diabetes: quality of life study
This trial tests whether a diabetes medicine called empagliflozin can improve the quality of life for people who have both chronic heart failure with a weak heart pump and type 2 diabetes. It compares the effects of adding empagliflozin to your current treatments.
Karachi, SindhAges 40–70 - NCT06889662Recruiting
Genetic testing study for arrhythmic myocarditis
This study tests whether looking at your genes can help doctors understand and treat arrhythmic myocarditis (a type of heart muscle inflammation that can cause irregular heartbeats). It may help find better treatments for people with this condition.
Milan, Italy/MilanAges 10–80 - NCT06890169Recruiting
One-stop telehealth program for weight and diabetes
This trial tests a telehealth program that helps people lose weight and manage type 2 diabetes and fatty liver disease at the same time. It's a one-stop remote clinic that combines medical advice, nutrition, and lifestyle support.
SingaporeAges 21–70 - NCT07270718Recruiting
Beetroot powder for blood pressure in men with hypertension
This trial tests whether taking 20 grams of beetroot powder daily can help lower blood pressure and improve blood flow in men who already have high blood pressure under control with medication. Beetroot is rich in nitrates, which may relax blood vessels.
MoscowAges 18–60 - NCT07278089Recruiting
AF screening for people with heart changes on echo
This trial checks if people with certain heart conditions seen on an echo (like an enlarged heart or stiff heart muscle) have undetected atrial fibrillation (AF). It aims to find AF early so it can be treated to prevent strokes.
TaipeiAges 20 years+ - NCT07277686Recruiting
AI face scan for hidden heart disease in high-risk people
This trial tests whether an AI system can detect signs of coronary artery disease (blockages in heart arteries) by analyzing a photo of your face. It may help identify people in the community who need further heart testing.
Zhoukou, HenanAges 18 years+ - NCT07275931Recruiting
Digital support program for heart failure patients
Researchers in Sweden are testing a digital support program to help patients with heart failure manage their condition at home. If you qualify, you'll use a smartphone or computer-based program that may offer tips, tracking, and help from a care team.
Linköping, Östergötland CountyAges 18 years+ - NCT07270692Recruiting
Detecting weak heart pump with AI and ECG
This study tests if an artificial intelligence program can detect a weak heart pump (low ejection fraction) using a simple three-lead electrocardiogram (ECG), which is a quick heart tracing test. It could help find heart problems earlier without needing a full ultrasound.
Mumbai, MaharashtraAges 18 years+ - NCT07278310Recruiting
Siegel Valve for Severe Aortic Stenosis (TAVR)
This study tests a new replacement valve called the Siegel, placed through a catheter in your leg (TAVR), for people with severe aortic stenosis. It aims to see if it is safe and effective for patients at low, intermediate, or high surgical risk.
Atlanta, GeorgiaAges 18 years+ - NCT07277582RecruitingPhase 2/Phase 3
Study of a new medicine for long QT syndrome types 2 and 3
This study tests a new medicine called THRV-1268 to see if it can safely improve heart rhythm in people with Long QT syndrome types 2 and 3. It may help reduce the risk of dangerous heart rhythm problems.
Scottsdale, ArizonaAges 15 years+ - NCT07269717RecruitingPhase 2
Testing HRS-1893 for heart failure with preserved ejection fraction
This trial tests a new drug called HRS-1893 for people with heart failure with preserved ejection fraction (HFpEF). It aims to see if the drug can improve symptoms and quality of life.
Shanghai, Shanghai MunicipalityAges 40 years+ - NCT07278869Recruiting
Study of Append system for atrial fibrillation patients
This trial tests a new device, the Append System, to close off the left atrial appendage (a small pouch in the heart) in people with atrial fibrillation. The goal is to reduce stroke risk without needing long-term blood thinners.
Jonesboro, ArkansasAges 18 years+ - NCT07276282RecruitingPhase 3
Ziltivekimab for heart attack patients with artery plaque
This trial tests a new drug called Ziltivekimab to see if it can reduce plaque buildup in the heart arteries after a heart attack. It may help prevent future heart problems by targeting inflammation.
BernAges 18 years+ - NCT07273877Enrolling by invitation
Blood pressure control with the Netrod RDN system
This study is for people with high blood pressure who are already using or planning to use the Netrod RDN system, a device that uses radiofrequency energy to treat the nerves around the kidneys. The study aims to see how well this system controls blood pressure in real life.
Beijing, Beijing MunicipalityAges Any age - NCT07276711Recruiting
Protecting brain during TAVR with EmStop device
This trial tests a new device (EmStop) that helps protect your brain during TAVR (a type of heart valve replacement). The device is placed in arteries to catch any debris that might break loose during the procedure, potentially reducing the risk of stroke.
Thousand Oaks, CaliforniaAges 22 years+ - NCT07271238Recruiting
Study of a new imaging system for heart ablation
This study tests a new imaging system (VERAFEYE) that helps doctors guide catheter ablation, a procedure to fix irregular heartbeats like atrial fibrillation. It aims to see if the system makes the procedure safer or more effective.
SplitAges 18 years+ - NCT05332457Recruiting
Beta-blocker effects on heart rate and exercise capacity in atrial fibrillation
This study looks at how taking a beta-blocker affects your resting heart rate during activity and how fit your heart and lungs are during an exercise test. It may help clarify whether the way the medication controls heart rate is linked to better exercise tolerance in people with persistent atrial fibrillation.
TaipeiAges 20 years+ - NCT06354881Recruiting
Blood flow in the brain after lacunar stroke
This study looks at how well-controlled blood pressure and diabetes affect blood flow in the brain after a small type of stroke called lacunar stroke.
Leicester, LeicestershireAges 18 years+ - NCT06598683Recruiting
Brain stimulation for muscle stiffness after stroke
This study tests whether a gentle, non-invasive brain stimulation (tDCS) can help reduce muscle stiffness and improve arm or leg movement in people who had a stroke. If you have tight or stiff muscles after your stroke, this might be a good option to explore.
Rawalpindi, Punjab ProvinceAges 30–70 - NCT07270172Recruiting
Micronutrient study for type 1 diabetes complications
This study tests how a specific drug affects heart and kidney health in people with type 1 diabetes who already have some complications like kidney disease, heart problems, or obesity. It aims to find new ways to prevent further damage.
Aarhus NAges 40 years+ - NCT07276087Recruiting
Physical and Mental Health in Takayasu Arteritis and Behçet's Disease
This study compares physical and mental health in people with Takayasu arteritis or Behçet's disease to healthy volunteers. It aims to better understand how these conditions affect day-to-day life and well-being.
Denizli, DenizliAges 18 years+ - NCT07272395Recruiting
Heart function changes after pacemaker or ICD placement
This study looks at how heart devices (pacemakers, ICDs, or CRT devices) affect the right side of the heart. Participants will have imaging tests before and after the device is placed to see how the heart functions.
Istanbul, FATIHAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,626 recruiting cardiology studies from the U.S. registry right now, out of 14,734 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.