Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,626 recruiting studies in this area right now.
By phase
- Not applicable7,647
- Phase 4471
- Phase 2470
- Phase 3439
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke798
- Heart Failure538
- Hypertension390
- Cardiovascular Diseases374
- Coronary Artery Disease361
- Multiple Myeloma328
- Atrial Fibrillation258
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke138
- Pulmonary Hypertension105
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Acute Coronary Syndrome74
- Obesity74
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine57
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona183
- Massachusetts174
- New York165
- Florida141
- Texas122
- Maryland119
- Minnesota118
- Illinois111
Recruiting studies9,626 total
- NCT07234422RecruitingPhase 3
Selenium and CoQ10 for heart failure
This study tests whether adding selenium and CoQ10 (two natural supplements) to standard heart failure treatment helps people with chronic heart failure feel better and improve their health. Researchers are using a registry-based approach to track participants in the Netherlands.
AlkmaarAges 18 years+ - NCT06908759Recruiting
Fall risk in older adults after heart rehab
This study looks at whether a special cardiac rehab program can help older adults who recently had a heart event improve their balance and reduce their risk of falling. It's designed for people age 65 and older who are now stable enough to begin rehab.
Rome, RMAges 65 years+ - NCT03945968Recruiting
Risk scores after abdominal surgery for people with health conditions
This study looks at how other health problems affect the chance of postoperative complications after abdominal surgery. It aims to help doctors better predict risk and decide on the safest care for you.
ArkhangelskAges 18 years+ - NCT04412187Recruiting
Study of inflammation after a new stroke
This study looks at inflammation-related changes soon after an acute ischemic stroke (a type caused by a blocked blood vessel). It may help researchers understand what factors drive recovery and how they could be targeted in the future.
Munich, GermanyAges 50 years+ - NCT05201144RecruitingPhase 2
Test of sildenafil after diaphragm hernia surgery in newborns
This trial studies whether sildenafil (a medicine that helps relax blood vessels) can improve outcomes in babies born with a congenital diaphragmatic hernia (CDH) after they’ve had surgery. Babies are selected based on an ultrasound/echo of heart function after repair.
Salt Lake City, UtahAges Any age - NCT05329714Recruiting
Deep testing registry for people with pulmonary hypertension
This trial is a global registry that collects detailed health information (“deep phenotyping”) from people diagnosed with pulmonary hypertension. It helps researchers better understand the condition and how people differ, which can guide better future treatments.
Giessen, HesseAges Any age - NCT05565781Recruiting
Watch for hidden atrial fibrillation after unexplained stroke
This study uses a smartwatch and a longer heart-monitoring test (a Holter) to find an irregular heart rhythm called atrial fibrillation after a stroke whose cause is unclear. If they detect it, it may help guide better prevention and treatment to reduce future stroke risk.
Barcelona, CataloniaAges 55 years+ - NCT05199194RecruitingPhase 3
Clot-busting before or during procedure for acute stroke
This study compares two treatment approaches for a stroke caused by a blocked brain artery: doing a procedure to remove the clot alone versus giving an IV clot-busting medicine first (tenecteplase). It aims to see which approach works better and is safest for improving recovery.
Porto Alegre, Rio Grande do SulAges 18–85 - NCT05635227Recruiting
Medications during heart surgery to help control breathing and circulation
This study looks at whether giving dexamethasone and olanzapine during certain heart surgeries can improve how blood flow and ventilation (breathing support) are managed. It’s meant to see if these medicines help the body handle heart-lung bypass more safely.
CopenhagenAges 18 years+ - NCT05199662RecruitingPhase 3
IV clot-busting medicine for stroke when standard options don’t fit
This trial tests whether giving IV TNK (tenecteplase) plus standard stroke care can improve outcomes in some people who have a new stroke but cannot get alteplase (another clot-busting drug) and do not have a large blocked artery that can be treated with a procedure. It’s meant for strokes with “mismatch” findings on scans that suggest salvageable brain tissue.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT05553223Recruiting
Very small activity doses for COPD symptoms
This study tests whether “micro-doses” of physical activity (short, small amounts) can help people with COPD. It aims to see if these small activity bursts are safe and beneficial for people who have stable COPD.
Kelowna, British ColumbiaAges Any age - NCT05582044Recruiting
Exercise using leg suction for heart failure with preserved function
This study tests whether a specific lower-body exercise method using negative pressure (leg suction) can improve symptoms and heart-related function in people with heart failure with preserved ejection fraction (HFpEF). You may also be offered screening if you are a healthy person, to compare results.
Kelowna, British ColumbiaAges 40 years+ - NCT05880680Recruiting
SEAL device registry for certain brain aneurysms treated through blood vessels
This study follows people who have a brain aneurysm that can be treated using the SEAL device placed from inside a blood vessel. It aims to track how well the treatment works and how safely it can be used in real-world care.
Itagüi, MedellínAges 18–80 - NCT05962164Recruiting
Passive heat therapy for COPD in non-smokers
This study tests whether using passive heat (warming therapy, not exercise) can improve breathing and body comfort in people with COPD who are not currently flaring up. It may help by seeing if heat changes how well you tolerate breathing and physical activity during testing.
Kelowna, British ColumbiaAges 40 years+ - NCT06061185Recruiting
CT scans for recent hemorrhagic stroke
This study uses advanced CT scans to get a better look at bleeding in the brain (hemorrhagic stroke). It may help doctors understand the stroke and guide care.
Beijing, Beijing MunicipalityAges 18–85 - NCT06100770Recruiting
Aveir leadless pacemaker study for Medicare patients
This study looks at how well a new type of pacemaker, called Aveir AR, works for people with Medicare. It helps doctors understand if this leadless pacemaker is safe and effective for treating slow heart rhythms.
Sylmar, CaliforniaAges 18 years+ - NCT07221682RecruitingPhase 2/Phase 3
Comparing two nerve block methods for lower leg surgery
This study compares two ways of giving a nerve block (fascia iliaca block) to help with positioning for spinal anesthesia and pain relief after lower leg surgery. The goal is to see which method works better for making patients more comfortable.
Sāhīwāl, Punjab ProvinceAges 30–60 - NCT06618612Recruiting
Wound matrix for diabetic foot ulcers
This study tests if a special wound dressing (collagen matrix with antimicrobial) plus standard care helps diabetic foot ulcers heal better than standard care alone. It's for people with diabetes who have a foot sore that hasn't healed for at least 4 weeks.
Clevland, OhioAges 18 years+ - NCT07230067Recruiting
Sepsis with low platelets: platelet transfusion study
This study looks at whether platelet transfusions help patients with sepsis and very low platelet counts recover better. If you or your loved one had sepsis, a low platelet count, and were in the ICU for at least two days, this trial may be relevant.
Guangzhou, GuangdongAges 18 years+ - NCT07229248RecruitingPhase 3
Balloon vs. Stent in Young Heart Attack Patients
This trial compares a drug-coated balloon (DCB) to a drug-eluting stent (DES) in younger adults having their first major heart attack. The goal is to see which treatment works better when the artery is opened quickly.
KarachiAges 18–49 - NCT07226609Recruiting
Plant-based diet study for multiple myeloma patients
This study tests if a plant-based diet can help people with newly diagnosed multiple myeloma who are receiving a standard 4-cycle drug combination (DRVd). Researchers want to see if changing what you eat might improve treatment results.
Basking Ridge, New JerseyAges 18 years+ - NCT07222683Recruiting
How kidney transplant affects heart blood vessel health
This study looks at how receiving a kidney transplant changes the health of small blood vessels in the heart. It may help people with advanced kidney disease understand the benefits of transplant on their heart health.
Boston, MassachusettsAges 18 years+ - NCT07223242RecruitingPhase 2/Phase 3
Tailored exercise training for heart failure with preserved pumping strength
This trial tests a personalized exercise program to help people with a type of heart failure called HFpEF. You may qualify if your heart still pumps well but you have trouble being active, and you are willing to use a phone app and exercise regularly.
Dallas, TexasAges 18 years+ - NCT07224230Recruiting
Custom aortic graft study for high-risk aneurysm patients
This study tests a doctor-modified aortic graft for people with complex aortic aneurysms who cannot use standard approved devices. The goal is to see if this custom approach can repair the aneurysm safely in high-risk patients.
Houston, TexasAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,626 recruiting cardiology studies from the U.S. registry right now, out of 14,734 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.