Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,626 recruiting studies in this area right now.
By phase
- Not applicable7,647
- Phase 4471
- Phase 2470
- Phase 3439
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke798
- Heart Failure538
- Hypertension390
- Cardiovascular Diseases374
- Coronary Artery Disease361
- Multiple Myeloma328
- Atrial Fibrillation258
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke138
- Pulmonary Hypertension105
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Acute Coronary Syndrome74
- Obesity74
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine57
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona183
- Massachusetts174
- New York165
- Florida141
- Texas122
- Maryland119
- Minnesota118
- Illinois111
Recruiting studies9,626 total
- NCT07227311RecruitingPhase 2
Belantamab mafodotin combinations for relapsed multiple myeloma
This trial tests a new drug called belantamab mafodotin (a targeted antibody therapy) combined with standard treatments for multiple myeloma that has come back or stopped responding. It looks at three different drug combinations to see which works best for people who have had 1 or 2 prior treatments.
Los Alamitos, CaliforniaAges 18 years+ - NCT07224906Recruiting
Observing patients having a right heart catheterization
This study observes people who are already scheduled for a right heart catheterization, a procedure that checks the pressure in your heart. It helps doctors learn more about heart conditions without adding any extra treatments or procedures.
Boulder, ColoradoAges 18 years+ - NCT07222293Recruiting
Testing an AI tool to screen for diabetic eye disease
This study uses an AI program called DRISTi to screen for diabetic eye disease by taking pictures of the back of your eye. It's designed for adults with diabetes who haven't had major eye treatments or vision loss.
Oxford, North CarolinaAges 21 years+ - NCT07225075Recruiting
Silk Vista Baby flow diverter for brain aneurysms
This trial tests a device called Silk Vista Baby that is placed inside a blood vessel to treat a brain aneurysm (a weak spot in a blood vessel) that hasn't burst. The goal is to see if it helps prevent the aneurysm from growing or bursting.
Thousand Oaks, CaliforniaAges 22–80 - NCT07222813Recruiting
Liver scan to detect high blood pressure in the heart
This trial uses a special liver scan (FibroScan) to measure liver stiffness, which may help detect high pressure in the central veins returning blood to the heart. It is for people with heart failure who are already scheduled for a right heart catheterization.
Los Angeles, CaliforniaAges 18 years+ - NCT07224256Recruiting
Brain implant trial to help with communication after injury or disease
This trial tests a brain-computer interface (BCI) that is implanted by a robot. It is designed to help people who have lost the ability to speak clearly or use their hands well, due to conditions like ALS, stroke, or spinal cord injury.
Dallas, TexasAges 22–75 - NCT07221851RecruitingPhase 3
Weekly vs daily growth hormone for short stature in children
This trial tests a weekly growth hormone injection (lonapegsomatropin) compared to the standard daily growth hormone shot in children with short stature due to certain conditions. It aims to see if the weekly shot works as well or better and is safe.
Palo Alto, CaliforniaAges 2–17 - NCT07227532Recruiting
Testing a new catheter for atrial fibrillation treatment
This study tests a new catheter system, called Varipulse, to see if it's safe and effective for treating atrial fibrillation (AF), a heart rhythm problem. People with short-lasting AF who haven't been helped by medication may be able to join.
Phoenix, ArizonaAges 22 years+ - NCT07228312Recruiting
Stent treatment for unruptured brain aneurysm
This study tests a flexible stent (Choydar flow-directed mesh) to treat unruptured brain aneurysms in the neck area of the carotid or vertebral arteries. It is for people whose aneurysm has not bled and fits certain size and shape limits.
ChenzhouAges 18 years+ - NCT06911710RecruitingPhase 1/Phase 2
Car-T therapy for relapsed blood cancers
This trial tests whether CAR-T cells, a type of immunotherapy that targets specific markers on cancer cells, can treat blood cancers that have come back or not responded to standard treatment. It may offer a new option for people with lymphoma, leukemia, or multiple myeloma.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT05334615Recruiting
Study of blood clot problems after COVID or flu
This study looks at blood clot–related complications after COVID-19 (and in some cases flu) in adults admitted to the hospital. It may help doctors better understand and manage these complications.
Iowa City, IowaAges 18–99 - NCT04680442RecruitingPhase 2
Keeping HER2 therapy when your heart function is weaker
This trial studies whether it’s safe to continue HER2-targeted breast cancer treatment (like trastuzumab, pertuzumab, or T-DM1) even when heart function (left ventricle) is reduced. It may help people avoid stopping a helpful cancer medicine because of heart concerns.
Porto Alegre, Rio Grande do SulAges Any age - NCT05686447Recruiting
Testing blood samples to study multiple myeloma
This study looks at stored blood (serum) samples to see whether a lab test called MALDI-TOF mass spectrometry can help analyze multiple myeloma proteins. If you have multiple myeloma (or are a healthy matched control), your existing lab samples may be used for testing.
Guangzhou, GuangdongAges Any age - NCT06214429Recruiting
Shear wave test for carotid plaque stiffness
This trial uses a special ultrasound technique called shear wave elastography to measure how stiff fatty deposits (plaques) are in your neck arteries. It aims to see whether plaque stiffness can help doctors better understand your stroke risk.
Botucatu, São PauloAges 18 years+ - NCT06320132Recruiting
Study on brain bleed recovery in the ICU
This study looks at how patients recover after a sudden, non-traumatic brain bleed. It aims to learn more about their brain function and daily living skills over time.
Milan, MIAges 18 years+ - NCT06340152Recruiting
Studying maternal health after preeclampsia
This trial follows women who have had preeclampsia to learn more about their health after pregnancy. It collects blood and tissue samples to find markers that could improve future care.
San Diego, CaliforniaAges 18–50 - NCT06325488Recruiting
Kidney Health Study in Fabry Disease
This study uses MRI scans to look at how Fabry disease affects the kidneys, including scarring, swelling, and oxygen levels. It may help researchers understand kidney problems better and find new ways to monitor the disease.
CopenhagenAges 18 years+ - NCT06911099Recruiting
Studying mitral valve repair for atrial regurgitation
This trial tests a minimally invasive procedure (transcatheter edge-to-edge repair) to fix a leaky mitral valve caused by an enlarged atrium, not by heart muscle damage. It might be an option if your mitral regurgitation is related to atrial issues and your heart's pumping strength is normal.
The Bronx, New YorkAges 18 years+ - NCT06560762RecruitingPhase 1
Study of a new drug for heart failure with preserved pumping ability
This trial tests an investigational drug for people with a type of heart failure where the heart pumps normally but is stiff. The goal is to see if the drug can improve symptoms and quality of life.
Chicago, IllinoisAges 18 years+ - NCT06887231Recruiting
Virtual reality and brain stimulation for early stroke recovery
This study tests whether using virtual reality (a special headset with games) combined with mild electrical stimulation on the scalp can help people recover arm movement early after a stroke. It is for people who already have some movement in their affected arm and are in the subacute phase (1 week to 3 months after stroke).
Vienna, State of ViennaAges 18–80 - NCT06735898Recruiting
A combined therapy for recovery after intensive care
This trial tests a combination of CYTOFLAVIN (given as an IV and later as a pill) to help people with long-term symptoms after spending time in the ICU. It aims to improve muscle weakness, breathing, swallowing, and energy levels during later stages of rehabilitation.
Yekaterinburg, Sverdlovsk OblastAges 18 years+ - NCT06907186Recruiting
Psychological support program for amyloidosis patients and families
This study tests a structured psychological support program for people with hereditary transthyretin amyloidosis (ATTRv) with heart involvement, their caregivers, and those who carry the gene but have no symptoms yet. The goal is to see if the program is practical and well-accepted.
PaviaAges 18 years+ - NCT06903845Recruiting
Apixaban study for atrial fibrillation
This trial tests whether apixaban, a blood thinner, works well for people with atrial fibrillation who also have heart or circulation conditions. It uses a smartphone app to help track your treatment.
Seongnam, GyeonggidoAges 19 years+ - NCT06914336Recruiting
Liver ultrasound to check fluid buildup in ventilated patients
This trial uses an ultrasound of your liver to see if there is extra fluid or pressure in your veins that might make it harder to breathe. It may help doctors understand how to better manage the breathing machine for people who have been on it for more than a day.
BrestAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,626 recruiting cardiology studies from the U.S. registry right now, out of 14,734 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.