Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,062 recruiting studies in this area right now.
By phase
- Not applicable8,033
- Phase 2488
- Phase 4482
- Phase 3452
- Phase 1360
- Phase 1/Phase 2161
- Phase 2/Phase 386
Top conditions
- Stroke856
- Heart Failure567
- Hypertension402
- Cardiovascular Diseases390
- Coronary Artery Disease373
- Multiple Myeloma329
- Atrial Fibrillation273
- Ischemic Stroke199
- Atrial Fibrillation (AF)146
- Acute Ischemic Stroke141
- Pulmonary Hypertension103
- Myocardial Infarction98
- Congenital Heart Disease86
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis78
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California466
- Alabama199
- Massachusetts182
- Arizona176
- New York166
- Florida145
- Illinois120
- Maryland120
- Minnesota120
- Texas120
Recruiting studies10,059 total
- NCT02827032Recruiting
Device study to help lower high blood pressure
This study tests whether the MobiusHD™ device can help lower blood pressure in people whose pressure stays high despite stable medicine. You may be screened for related nerve control problems and will likely need specific testing of your heart rate/nerve function.
Mannheim, Baden-WurttembergAges 18–80 - NCT02417740Recruiting
Study of the natural course of noncirrhotic portal hypertension
This study follows people with noncirrhotic portal hypertension (NCPH) or people at risk for it to better understand how the condition progresses over time. It does not sound like a medication trial—more like careful monitoring to learn what happens in different people.
Bethesda, MarylandAges 12–100 - NCT02664831Recruiting
Study of inflammation after cardiac arrest in ICU patients
This trial looks at how the body’s inflammation response behaves after someone has a cardiac arrest and was treated in the ICU. It may help doctors understand which patients could benefit from treatments that target harmful inflammation after resuscitation.
Portland, MaineAges 18 years+ - NCT02548546Recruiting
Imaging study to measure the aorta using new techniques
This study uses special imaging to better measure how the aorta wall behaves in people with an enlarged aorta (an aneurysm) and in some people without an aneurysm. Results may help doctors understand aneurysm risk and plan care more precisely.
Jacksonville, FloridaAges 18 years+ - NCT02113644Recruiting
Prevent CardioKids for overweight children after the COACH program
This trial looks at ways to help children who are overweight or obese reduce future heart and health risks. It compares children in different groups based on weight and, for some, whether they are having elective surgery.
Maastricht, LimburgAges 6–18 - NCT02726555RecruitingPhase 3
Red yeast rice plus low-dose statin versus statin alone
This Phase 3 study compares whether taking red yeast rice plus a low-dose statin works better and is as safe as taking a standard statin alone. It aims to improve cholesterol (especially LDL) and reduce cardiovascular risk in people with mild, confirmed artery disease.
Wenzhou, ZhejiangAges 20–80 - NCT02855554Recruiting
MRI heart scan study for specific heart conditions
This study uses a special MRI approach to measure details of your heart muscle in people with certain heart problems. It may help researchers better understand how different conditions affect the heart and how those changes can be measured.
Charleston, South CarolinaAges 18–90 - NCT02114450Recruiting
Training with a leg exoskeleton after stroke
This trial tests a “human–machine” leg exoskeleton system to help people with stroke improve standing and walking during rehab. You may be able to participate if you have certain levels of disability and spasticity, can safely stand and walk with help, and don’t have skin, joint, or medical issues that would make training unsafe.
Houston, TexasAges 18–75 - NCT02118467RecruitingPhase 4
Testing medicines that raise blood pressure in ICU shock patients
This trial studies whether “blood pressure–supporting” medicines (given through a central line) work well and safely for adults in the ICU who have shock. Your team may use the results to improve care for people with low blood pressure and poor blood flow to organs.
Chicago, IllinoisAges 18 years+ - NCT02432092Recruiting
Genetic testing for heart muscle disease in children and families
This study looks at genetic (DNA) changes that may cause cardiomyopathy, a disease where the heart muscle is weakened. It may help families understand possible causes and inform future care.
Indianapolis, IndianaAges Any age - NCT02542683Recruiting
Physical activity program to support children’s brain development
This study looks at whether a structured physical activity program can support thinking and brain development in children around age 2–5. Your child may be eligible if they are having certain surgeries or fit a matched “control” group and do not have specific neurologic or heart-related issues.
New York, New YorkAges 2.5 years–6 years - NCT02748941Recruiting
Imaging study of narrowed neck arteries after stroke
This study looks at new imaging markers in people with significant narrowing of the carotid artery (the main artery in the neck). It compares people who recently had a stroke from that artery with people who have no recent stroke, to better understand stroke risk and artery disease.
BronAges 18 years+ - NCT02435940Recruiting
Registry for inherited eye vision conditions
This study is a registry, meaning it collects information about people with inherited retinal (retina) diseases. It may help researchers learn how these conditions progress and connect you with future studies or treatments.
Columbia, MarylandAges Any age - NCT02772367Recruiting
Make heart muscle cells from blood or skin in breast cancer
This study grows heart muscle cells from your blood or skin to better understand why some people develop heart problems from HER2 cancer treatments. You may be helping researchers learn how to predict and prevent treatment-related heart damage.
New York, New YorkAges 18 years+ - NCT02132741Recruiting
Eye imaging study in people with kidney disease
This study uses a painless eye scan to learn more about how kidney disease may be linked to eye changes. It may help improve understanding and future care for people with chronic kidney disease and/or high blood pressure.
Edinburgh, MidlothianAges 18–80 - NCT02141308Recruiting
OCT eye imaging for rare retinal and choroid diseases
This trial studies rare diseases affecting the retina or choroid using detailed eye scans (OCT). It may help doctors better understand how these conditions look in the eye and how imaging findings relate to vision.
Portland, OregonAges 7–100 - NCT02795052Recruiting
Stem cell treatment trial for nerve injury
This study tests whether bone-marrow stem cells can improve nerve function in people with nerve damage that usually doesn’t recover with current care. It also checks whether the treatment is safe and whether people can be followed over time with repeated nerve exams.
Westport, ConnecticutAges 18 years+ - NCT02756091Recruiting
Study of treatment after a new brain artery dissection
This study looks at people who have had a fresh tear in a brain artery within the last month. The goal is to learn the best way to manage this condition and improve outcomes.
Osaka, KansaiAges 18 years+ - NCT02134574Recruiting
Study of blood cancers in adults in southern France
This study follows adults who are being checked for a possible blood cancer, or who were recently diagnosed with a blood cancer within the last 6 months. It may help doctors understand the condition better and improve how early workups and care are organized.
MontpellierAges 18 years+ - NCT02682667Recruiting
Providing blood samples for cancer immunotherapy research
This study collects and stores blood/tissue samples (called biospecimens) to support immunotherapy research at the cancer center. If you may qualify, your samples help researchers test new immune-based cancer treatments.
Bethesda, MarylandAges 18–120 - NCT02808260Recruiting
Tracking what predicts abnormal heart rhythms after pacemaker
This study looks for patterns that can predict an abnormal heart rhythm called SCAF in people who have a pacemaker or defibrillator. The goal is to help doctors recognize risk earlier and respond sooner if it happens.
Ottawa, OntarioAges 18 years+ - NCT02797366RecruitingPhase 2
Proton beam radiation for adult brain and spine tumors
This trial studies whether proton radiotherapy can treat primary brain (and sometimes spine) tumors in adults. You may join because your tumor type and situation fit specific diagnoses, including some cases needing a re-treatment plan.
GothenburgAges 18 years+ - NCT02138695Recruiting
Study of outcomes after atrial fibrillation catheter ablation
This study follows people after a procedure called catheter ablation to treat atrial fibrillation (an irregular heart rhythm). It aims to learn which factors help predict outcomes, so future care can be better tailored.
SeoulAges 19 years+ - NCT02842424RecruitingPhase 4
Ramipril for walking pain from blocked leg arteries
This study tests whether ramipril (a blood-pressure medicine) can improve leg muscle problems linked to poor blood flow in people with chronic claudication—pain that limits walking. It’s mainly looking at changes related to oxidative stress and muscle scarring (fibrosis).
Omaha, NebraskaAges 18–90
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,062 recruiting cardiology studies from the U.S. registry right now, out of 15,523 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.