Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,981 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2482
- Phase 4481
- Phase 3449
- Phase 1361
- Phase 1/Phase 2164
- Phase 2/Phase 387
Top conditions
- Stroke841
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke201
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke138
- Myocardial Infarction100
- Pulmonary Hypertension100
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas117
Recruiting studies9,978 total
- NCT06155643Recruiting
Detecting heart murmurs in emergency patients
This trial is testing a device that listens to heart murmurs when you come to the hospital with symptoms like chest pain, shortness of breath, or fainting. It helps doctors find serious heart problems earlier.
Saint Joseph, MichiganAges 18 years+ - NCT06153888Recruiting
Heart strain during dialysis: a study on fluid removal
This study looks at how quickly fluid is removed during dialysis affects the heart. It may help find safer ways to manage fluid removal for people on hemodialysis.
UmeåAges 18 years+ - NCT06153563Recruiting
Mitral valve elasticity study during replacement
This trial measures the stretchiness (elasticity) of the mitral valve during surgery in people who are having it replaced. It helps doctors understand how valve stiffness relates to heart health.
Saint-EtienneAges 45 years+ - NCT06136637Recruiting
Monitoring glycocalyx to predict complications after heart surgery
This study will see if measuring a substance in your blood (glycocalyx) can help doctors predict problems after heart surgery that uses a heart-lung machine. The goal is to improve care after surgery.
RouenAges 18–80 - NCT06130033Recruiting
Study of circulation after life support is removed
This study looks at what happens to blood flow and organs after life support is withdrawn in people who are expected to pass away soon. It aims to understand the body's response during this time to improve future care.
Vancouver, British ColumbiaAges 19 years+ - NCT04804748Recruiting
DefiPace to help prevent heart rhythm problems after heart surgery
This study tests DefiPace in people who are having planned open-chest heart surgery (bypass and/or valve surgery) to see if it can help reduce certain post-surgery heart rhythm complications. Whether it’s usable depends on your planned procedure and specific health factors.
ViennaAges 18 years+ - NCT06128330RecruitingPhase 4
Bedside test for bleeding prevention drug in heart surgery
This study tests a quick bedside measurement of how well the drug tranexamic acid works to prevent bleeding during heart surgery. It may help doctors give the right dose to reduce blood loss.
BernAges 18–90 - NCT06792617Enrolling by invitationEarly Phase 1
Exercise for people on ECMO life support
This study tests if gentle exercise in bed can help people on ECMO (a life-support machine for heart and lungs) get stronger and recover faster. It is for adults in the ICU who are stable enough to move safely.
San Antonio, TexasAges 18 years+ - NCT07302659Recruiting
Comparing two aortic clamping methods in off-pump bypass
This study compares two ways to clamp the aorta during off-pump heart bypass surgery to see which is safer for your brain and body. If you are having bypass surgery without a heart-lung machine, you may be able to join.
BeijingAges 18 years+ - NCT07303777RecruitingPhase 2
Study of ABP-745 for people with atherosclerosis
This trial tests a new medication called ABP-745 to see if it helps people with atherosclerosis (hardening of the arteries). It is for people who are already taking a cholesterol-lowering medicine and who have had a special heart artery X-ray (coronary angiography).
Beverly Hills, CaliforniaAges 18–75 - NCT07724262Recruiting
Testing the Argos System to measure heart blood flow
This trial is testing a new system called Argos to see if it can measure how much blood your heart pumps more easily than current methods. It is for patients already in the ICU who need a quick change in fluids or blood pressure medicine.
Le Kremlin-BicêtreAges 18 years+ - NCT07305389Recruiting
Music and exercise in cardiac rehab
This study tests how different types of music affect your mood during exercise in a cardiac rehabilitation program. It may help make your rehab workouts more enjoyable.
GenevaAges 50–75 - NCT05738408Recruiting
Remote smoking help for hospitalized heart patients
This trial tests a phone-based (remote) smoking quit program for people hospitalized for a recent heart-related event. It may help you quit smoking by offering support when you’re in the hospital and afterward.
Burlington, VermontAges 18 years+ - NCT06388382Recruiting
Testing the beep of a special defibrillator
This study looks at the beeping sound (alert tone) from a certain type of defibrillator placed under the skin. The goal is to understand if patients can hear and recognize these sounds, which could be important for safety.
CologneAges 15–100 - NCT07649005Recruiting
How Salt and Potassium Affect Blood Vessel Health in Older Adults
This study explores how different amounts of sodium (salt) and potassium in your diet affect your blood vessels and heart health. Researchers will monitor your blood pressure and vascular function over time to understand these dietary effects better.
Tallahassee, FloridaAges 55–75 - NCT07673536Recruiting
Heart transplant monitoring with extracellular vesicles
This study uses tiny particles called extracellular vesicles (which cells release) to check for signs of organ rejection after a heart transplant, aiming for a safer and less invasive alternative to biopsies.
Berlin, State of BerlinAges 18 years+ - NCT07318103RecruitingPhase 2
Study of HRS-9057 for fluid retention in heart failure
This trial tests an investigational drug, HRS-9057, in people hospitalized with heart failure who still have fluid buildup despite taking standard diuretics. The goal is to see if HRS-9057 helps remove excess fluid better than current treatments.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05345483Recruiting
Rescue stent after failed clot removal in brain arteries
This trial looks at using a special stent device to reopen a blocked brain artery when a standard clot-removal procedure did not work. It may help restore blood flow and reduce damage, especially when the stroke area on scans is small enough and the symptoms started within 24 hours.
AschaffenburgAges 18 years+ - NCT07735156Recruiting
Treating Pelvic Pain with Vein Blockage
This study tests a minimally invasive procedure that blocks abnormal veins in the pelvis to relieve long-term pelvic pain. It may help women with pelvic congestion syndrome.
Sohag, Sohag GovernorateAges 17–55 - NCT04471129Recruiting
Noninvasive breathing support after heart surgery to protect heart function
This study tests whether two noninvasive breathing/oxygen treatments after cardiac surgery help improve heart function. It may benefit people with weak pumping function who are recovering in the hospital and can safely use these devices.
RouenAges 18 years+ - NCT06786819Recruiting
Recovery app after heart bypass surgery
This study tests whether a smartphone app that helps you follow a recovery plan can shorten the time you need to stay in the hospital after coronary artery bypass (heart bypass) surgery. If you are scheduled for this surgery, have a smartphone, and are comfortable using it, this app might help you get home sooner.
São Paulo, São PauloAges 18 years+ - NCT07212686Enrolling by invitationPhase 4
Angiotensin II for severe low blood pressure in children
This study tests an IV medicine called angiotensin II (Giapreza) to raise blood pressure in children who are very sick and not responding to standard treatments. It aims to see if this medicine can help stabilize blood pressure and improve outcomes.
New Hyde Park, New YorkAges birth–18 years - NCT07726251Recruiting
Heart changes during jaw surgery
This study looks at how your heart and blood pressure change during a type of jaw surgery called bimaxillary orthognathic surgery. It will help doctors understand a reflex that can affect your heart rate during the procedure.
Kirikkale, KırıkkaleAges 18–40 - NCT07328958Recruiting
Ciprofol dosing for blood pressure in elderly abdominal surgery patients
This study tests if giving the sedative ciprofol in carefully adjusted doses can prevent low blood pressure during and after laparoscopic belly surgery in older adults. It may help your surgical team keep your blood pressure stable.
Guangzhou, GuangdongAges 65 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,981 recruiting cardiology studies from the U.S. registry right now, out of 15,236 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.