Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT06680986Recruiting
AI heart ultrasound study for high blood pressure
This trial uses artificial intelligence to analyze heart ultrasound images from people who had high blood pressure evaluations during a hospital stay. It aims to better understand how high blood pressure affects the heart.
Pierre-BéniteAges 18 years+ - NCT06678698Recruiting
Light therapy for blood pressure control in adults
This trial tests light therapy (photobiomodulation) to see if it helps people with high blood pressure who still have trouble controlling it with medication. It is a short study looking at an acute effect.
São Carlos, São PauloAges 40–60 - NCT06680791Recruiting
Endometrial cancer study on recurrence prevention and lifestyle
This study looks at how your cancer type and daily habits might help prevent endometrial cancer from coming back. It only requires that you've had endometrial cancer and a hysterectomy.
PragueAges Any age - NCT06681506Recruiting
New heart rehab program for ischemic heart disease
This study tests a new cardiac rehabilitation treatment for people with ischemic heart disease, a condition where blood flow to the heart is reduced. The goal is to improve heart health and recovery through a structured rehab program.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT03892174Recruiting
Removing inflammatory signals during heart surgery for endocarditis
This study tests whether removing certain inflammation signals (cytokines) can help people with severe heart infection (infective endocarditis) who are having heart surgery soon. It may help reduce harmful inflammation around the time of surgery, but it also has several medication and health-condition requirements.
BernAges 18 years+ - NCT06684171Recruiting
Comparing two ways to guide mitral valve clip repair
This trial tests whether using only ultrasound (echo) to guide a mitral valve clip repair is as good as using ultrasound plus X-ray. The study may help patients with a leaky mitral valve who are not good candidates for open heart surgery.
Shenzhen, GuangdongAges Any age - NCT06669884Recruiting
New ECG method to quickly sort chest pain in ER
This study tests a new ECG-based technology that may help doctors more quickly sort out the cause of your chest pain in the emergency room. If you have chest pain that needs checking, this tool could help decide how urgent your care is.
Jinan, ShandongAges 18 years+ - NCT07651306Recruiting
Bone Loss After Stroke: New X-ray Detection Method
This study tests whether a new way of measuring X-rays can detect bone loss in the shoulder after a stroke. The research may help doctors identify patients at risk for fractures earlier.
IstanbulAges 18 years+ - NCT07648693Recruiting
Brain Protection Device During Aortic Valve Replacement
This trial tests a new device called CHORDS that protects your brain during transcatheter aortic valve replacement (TAVR), a minimally invasive procedure to fix a narrow aortic valve. The device works by blocking debris that might travel to your brain during the procedure.
Bengbu, AnhuiAges 18 years+ - NCT07646600Recruiting
Natural History Study of BAG3 Heart Disease in Chinese Adults
This study follows adults with a specific genetic mutation (BAG3) that causes heart muscle weakness. Researchers will track how the disease develops over time to better understand it and help improve future treatments.
BeijingAges 18 years+ - NCT07654829RecruitingPhase 4
Sebetralstat to prevent swelling before procedures in HAE
This trial tests if sebetralstat can prevent swelling attacks before medical procedures in people with HAE types I or II. You take the medicine short-term before your procedure to see if it helps protect you from an attack.
Colorado Springs, ColoradoAges 12 years+ - NCT07648264RecruitingPhase 3
Immune Boost Treatment After CAR-T or TCE Therapy
This study tests a new immunoglobulin (antibody) treatment called IgPro20 in adults whose immune systems became weakened after receiving CAR-T cell or TCE therapies for blood cancers. The goal is to help strengthen your immune system and reduce infection risk.
Orange, CaliforniaAges 18 years+ - NCT07646704Recruiting
Study of HeartR PDA Heart Device Safety and Function
This study follows patients who had a small heart device (HeartR PDA Occluder) placed to close an opening in their heart called a PDA. Researchers will check how well the device is working and track the patient's health over time.
Pekanbaru, RiauAges 6 months+ - NCT07646782Recruiting
Human Observatory Study: Aging and Longevity Research
This study observes how people age over time to better understand what helps people live longer and healthier lives. You'll share health information through surveys or online screening, and researchers will track changes in your health and wellbeing.
Boulder, ColoradoAges 18 years+ - NCT07652281RecruitingPhase 1
Study of SHR-5421 for multiple myeloma
This trial tests a new drug, SHR-5421, for people with multiple myeloma that has come back or stopped responding to treatment. It aims to see if the drug is safe and how well it works.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07654140RecruitingPhase 2
Testing a new drug for uncontrolled high blood pressure
This trial tests a new drug called SAL0140 for people whose high blood pressure is not controlled by current treatments. It may help lower blood pressure when other medications haven't worked well enough.
Beijing, Beijing MunicipalityAges 18–75 - NCT07654855Recruiting
Long-term safety of eplontersen in ATTR patients
This study follows people who already took part in an earlier trial (D8450R00003) to see how safe eplontersen is over the long term. It also includes people who had a liver transplant or severe liver problems.
Los Angeles, CaliforniaAges 18 years+ - NCT07647172Recruiting
Flavonoid Treatment for Hemorrhoids After Minimally Invasive Surgery
This study tests whether a plant-based medicine called MPFF (a purified flavonoid fraction) helps reduce symptoms and improve healing after minimally invasive surgery for hemorrhoids. You would take this medicine before and after your scheduled procedure.
MoscowAges 18 years+ - NCT07650032Recruiting
Freezing Treatment for Abnormal Heart Rhythms
This trial tests a freezing catheter procedure to treat dangerous, recurring abnormal heart rhythms (ventricular tachycardia) in patients whose hearts are weakened and whose current medications haven't worked. The procedure aims to scar the tissue causing the arrhythmia so your heart beats normally again.
Phoenix, ArizonaAges 18 years+ - NCT06055569Recruiting
Rehabilitation for arm recovery after stroke using observation and muscle stimulation
This trial tests if observing arm movements paired with muscle stimulation helps stroke survivors regain arm function. It may be an option if your stroke affected one arm and you are between two weeks and six months post-stroke.
Milan, ItaliaAges 18 years+ - NCT02756091Recruiting
Study of treatment after a new brain artery dissection
This study looks at people who have had a fresh tear in a brain artery within the last month. The goal is to learn the best way to manage this condition and improve outcomes.
Osaka, KansaiAges 18 years+ - NCT06130033Recruiting
Study of circulation after life support is removed
This study looks at what happens to blood flow and organs after life support is withdrawn in people who are expected to pass away soon. It aims to understand the body's response during this time to improve future care.
Vancouver, British ColumbiaAges 19 years+ - NCT07646418Recruiting
Light therapy and blood-flow restriction for stroke recovery
This study tests whether combining light therapy with blood-flow restriction exercise (a technique that limits blood flow during gentle movement) helps improve arm strength and reduce muscle stiffness in people recovering from stroke. The goal is to see if this combination works better than standard treatment.
Sialkot, Punjab ProvinceAges 50–70 - NCT07654426RecruitingPhase 2
Heart protection during lymphoma chemotherapy
This trial tests if a heart-protecting drug (dexrazoxane) can prevent heart damage in people getting chemotherapy for certain types of large B-cell lymphoma. It is for patients who already have heart risk factors or a history of heart failure.
Boston, MassachusettsAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.