Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT07646444Recruiting
Study of OPN Balloon for Opening Hardened Heart Vessel Blockages
This is a follow-up study of patients who have already had a heart procedure using a special balloon (OPN balloon) to open calcified (hardened) blockages in heart arteries. Researchers will review records to see how well this balloon works and how patients recover.
Minneapolis, MinnesotaAges 18 years+ - NCT07653659Recruiting
Lowering norepinephrine in shock: effects on blood vessel pressure
This study tests whether reducing the dose of a medicine that raises blood pressure (norepinephrine) affects how blood moves through the body in people with distributive shock. If you are on a steady low dose of norepinephrine and have a special heart monitor (PiCCO catheter), this trial may help doctors understand safer ways to wean the medicine.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07646522RecruitingPhase 2
Home-Based Arm Recovery Program After Stroke in Brazil
This study tests whether telehealth (video-guided) exercises can help people recover arm function after a recent stroke. You'll do exercises at home with remote support and guidance, and researchers will track your progress over 6 weeks.
Ribeirão Preto, São PauloAges 18–80 - NCT07648342Recruiting
Eye Pupil Response to Predict Pain After Heart Surgery
This study looks at how your eye pupils respond to light as a way to predict how much pain you might feel when sedation (sleep medicine) is stopped after heart surgery. The goal is to help doctors better manage your pain during recovery.
DijonAges 18 years+ - NCT07650435Recruiting
Clot removal in pulmonary embolism trial
This study tests a procedure to remove blood clots from the lungs in people with moderate or severe pulmonary embolism. It may help reduce strain on the heart and improve recovery.
PlymouthAges 18 years+ - NCT07649681Recruiting
AI nutrition help for taste changes from cancer treatment
This study tests whether an AI-powered nutrition program can help people with taste changes caused by cancer therapy. You'll get personalized recipe suggestions and nutrition advice through an online portal to help you eat better during treatment.
Augsburg, BavariaAges 18 years+ - NCT07649005Recruiting
How Salt and Potassium Affect Blood Vessel Health in Older Adults
This study explores how different amounts of sodium (salt) and potassium in your diet affect your blood vessels and heart health. Researchers will monitor your blood pressure and vascular function over time to understand these dietary effects better.
Tallahassee, FloridaAges 55–75 - NCT07650474Recruiting
Mobile app for heart failure management and quality of life
This study tests whether using a mobile phone app to monitor and manage chronic heart failure improves how you feel and function day-to-day. Researchers will check in with you regularly through your phone to track your symptoms and health.
Addis AbabaAges 18–65 - NCT07649135Recruiting
Remote Step-Counting Program for Stroke Recovery
This study tests whether a remote (at-home) program that tracks your daily steps and includes support from someone you know can help you become more physically active after a stroke. Researchers want to see if this approach is practical and if it helps people who had a stroke 6+ months ago move more.
Minneapolis, MinnesotaAges 18 years+ - NCT07654634Enrolling by invitation
Precision blood thinning therapy study
This trial tests personalized blood thinner treatment for people who need long-term anticoagulation for conditions like atrial fibrillation or blood clots. The goal is to find the safest and most effective dose for each patient.
Changsha, HunanAges 8 years+ - NCT07648446Recruiting
Learning About Pulses and Gut Health in Children
This study teaches children ages 6–13 about pulses (beans, lentils, chickpeas) and how they affect gut health. Researchers want to understand whether eating pulses helps children's digestive systems work better.
Tallahassee, FloridaAges 6–13 - NCT07652710Enrolling by invitation
Balance, arm function, and body awareness after stroke
This study looks at how balance, arm function, and body awareness are related in people who have had a stroke. It may help understand how these factors affect recovery and daily life.
Ankara, AnkaraAges 18–75 - NCT07651631Recruiting
Brain Bleeding Surgery Registry and Treatment Study
This study tracks patients who have had sudden, severe bleeding in the brain and received minimally invasive surgery (a less-invasive surgical approach) to treat it. Researchers want to understand outcomes and improve treatment for this serious condition.
Atlanta, GeorgiaAges 18 years+ - NCT07649616Enrolling by invitation
Training Law Enforcement to Use Heart-Restart Devices
This study helps police officers learn to use automated external defibrillators (AEDs)—machines that can restart a stopped heart during cardiac emergencies. The goal is to increase how often these devices are used and improve survival rates when officers respond to cardiac arrest calls.
Detroit, MichiganAges 18 years+ - NCT07649330Recruiting
Myofascial Release for Heart Surgery Recovery
This study tests whether a hands-on soft-tissue massage technique can help reduce pain and stiffness in patients recovering from open-heart surgery. The goal is to see if it speeds up healing and improves quality of life after the procedure.
Kaohsiung CityAges 18 years+ - NCT07648498Recruiting
Handgrip exercise for blood pressure and brain health in older adults
This study tests a simple handgrip exercise program (squeezing a device) done in the community to see if it can help lower blood pressure and improve thinking/memory in older adults. It is open only to people already at the Physical Activity Centre of Excellence at McMaster University.
Hamilton, OntarioAges 65 years+ - NCT07646418Recruiting
Light therapy and blood-flow restriction for stroke recovery
This study tests whether combining light therapy with blood-flow restriction exercise (a technique that limits blood flow during gentle movement) helps improve arm strength and reduce muscle stiffness in people recovering from stroke. The goal is to see if this combination works better than standard treatment.
Sialkot, Punjab ProvinceAges 50–70 - NCT07653165Enrolling by invitation
Wound therapy for chronic leg wounds
This trial is testing a new way to clean and treat chronic leg wounds using a special wound therapy and gentle suction. It may help wounds that have not healed for a long time.
Coconut Creek, FloridaAges Any age - NCT07646977Recruiting
Blood Clot Treatment for Heart Attack Recovery
This trial tests a new approach to treating blood clots during a heart attack to prevent damage to the small blood vessels in your heart. You would receive this treatment during an emergency catheterization procedure if you have signs of a major heart attack.
OdenseAges 18 years+ - NCT07647497Recruiting
Heart Imaging to Predict Outcomes in Pulmonary Embolism
This study uses ultrasound images of your heart to see how well the right side is working in people who have a blood clot in the lungs. The goal is to better predict which patients might be at higher risk and need more intensive care.
SohagAges 18 years+ - NCT07652970Recruiting
Home video therapy for severe stroke recovery
This study tests whether a new therapy done at home via video calls can help people with severe, long-lasting stroke regain leg movement and walking ability. If you have trouble walking or moving your leg on one side, this may be an option.
Chicago, IllinoisAges 18–80 - NCT07654426RecruitingPhase 2
Heart protection during lymphoma chemotherapy
This trial tests if a heart-protecting drug (dexrazoxane) can prevent heart damage in people getting chemotherapy for certain types of large B-cell lymphoma. It is for patients who already have heart risk factors or a history of heart failure.
Boston, MassachusettsAges 18 years+ - NCT07649525RecruitingPhase 3
Personalized myeloma treatment based on response and fitness
This trial tests whether tailoring myeloma treatment based on how well you respond to initial therapy and your overall health status can improve outcomes. You'll receive standard first-line treatment (three drugs: daratumumab, lenalidomide, and dexamethasone) and then be assigned to a personalized pathway based on your response and fitness level.
BristolAges 18 years+ - NCT04449523Recruiting
Check for hidden heart rhythm problems after silent brain strokes
This study looks at how often “silent” atrial fibrillation—an irregular heart rhythm that can be symptom-free—happens in people who have silent brain stroke spots on MRI. If it finds a link, it may help identify which patients might benefit from closer heart monitoring or prevention steps.
GrazAges 50 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.