Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT07611747RecruitingPhase 4
Ultrasound Screening to Prevent Heart Disease in Rheumatic Patients
This study tests whether using ultrasound to look at arteries in the neck can help prevent heart attacks and strokes in people with inflammatory joint diseases like rheumatoid arthritis or lupus. Researchers will use the results to guide treatment decisions.
Alicante, AlicanteAges 50 years+ - NCT07611136Recruiting
Brain Vessel Disease Progression After Different Stroke Types
This study examines how small blood vessel disease in the brain progresses differently depending on whether you've had a recent stroke. Researchers will use MRI scans to track changes over time and better understand this condition.
Ulm, Baden-WurttembergAges 18 years+ - NCT07610538Recruiting
Low-dose IL-2 study after heart bypass surgery
This study tests whether a low dose of a natural immune-boosting protein (IL-2) given after heart bypass surgery can help reduce heart damage. The treatment aims to activate special immune cells that protect heart tissue.
Cambridge, CambridgeshireAges 18 years+ - NCT07604467Recruiting
Understanding Stem Cells in Takotsubo Heart Syndrome
This study examines how certain stem cells (CD34+ cells) may contribute to takotsubo syndrome, a temporary heart condition often triggered by stress. By understanding this connection, researchers hope to improve treatment and recovery for patients with this condition.
Ljubljana, LjubljanaAges 18 years+ - NCT07607275RecruitingPhase 4
Chinese herbal medicine for managing high blood pressure
This trial tests whether a traditional Chinese herbal medicine called Yufeng Ningxin can help lower blood pressure in adults with newly diagnosed or ongoing high blood pressure. Researchers will measure how well it works compared to standard treatment.
BeijingAges 18–65 - NCT07611019Enrolling by invitationPhase 2/Phase 3
Colchicine to prevent heart rhythm problems after heart bypass surgery
This study tests whether taking colchicine (a common anti-inflammatory medication) before and after bypass heart surgery can prevent atrial fibrillation—an irregular heartbeat that sometimes occurs after surgery. Researchers hope this simple treatment might reduce complications and improve recovery.
TaipeiAges 20 years+ - NCT07606807RecruitingPhase 3
New clot-busting medication for stroke in the extended time window
This trial tests a new medication called rhTNK-tPA for treating acute ischemic stroke (a clot in the brain) up to 24 hours after symptom onset. The study uses simplified imaging to determine eligibility and aims to help patients recover better outcomes.
GuangzhouAges 18 years+ - NCT07604688Recruiting
Registry Study of Dural Arteriovenous Fistulas in China
This study collects information from patients diagnosed with abnormal blood vessel connections in or around the brain or spine. Researchers will track your diagnosis, treatment, and outcomes to better understand these conditions and improve care.
BeijingAges 18 years+ - NCT07607106Recruiting
New Wound-Healing Gel for Chronic Leg and Foot Ulcers
This trial tests a new gel (called BU002) designed to clean and help heal chronic open sores on the legs or feet. The gel may work better than current treatments for wounds that have been open for months and aren't healing on their own.
Santiago, Metropolitana de SantiagoAges 60 years+ - NCT07607093Recruiting
Early rhythm control for atrial fibrillation with tricuspid valve leakage
This trial tests whether treating atrial fibrillation (an irregular heartbeat) early helps patients who also have tricuspid regurgitation (leakage in a heart valve). Researchers want to see if controlling the heart rhythm early can improve outcomes for people with both conditions.
Seoul, SeoulAges Any age - NCT07609966Recruiting
Virtual Reality for Stroke Arm Recovery
This trial tests whether virtual reality exercises help stroke patients recover arm and hand movement faster and better. You'd use VR games alongside your regular rehabilitation therapy in the hospital and after going home.
GironaAges 18 years+ - NCT06711003Recruiting
Enhanced circulation therapy for recent stroke recovery
This trial tests whether a non-invasive treatment that boosts blood flow can help people recovering from a stroke. If you had a stroke within the last month and have moderate to moderately severe disability, you may be eligible to participate and potentially improve your recovery.
TaichungAges 20 years+ - NCT06711432Recruiting
Blood Pressure Management During Tumor Surgery and Brain Function
This trial compares different blood pressure management strategies during abdominal tumor surgery to see which one better protects cognitive function (thinking, memory, and clarity). It is for patients who have multiple stroke risk factors and are undergoing a lengthy surgery.
Hangzhou, ZhejiangAges 40–85 - NCT04533217Recruiting
Vertebroplasty for multiple myeloma back pain
This trial tests whether adding a procedure called vertebroplasty to usual care can better reduce back pain from multiple myeloma. It’s for people who have a small number of spine fractures in a specific area and significant pain.
Middelfart, Region SyddanmarkAges 18 years+ - NCT06712862Recruiting
Testing heart muscle health with PET/MR scan
This study uses a special imaging test (PET/MR) to check if damaged heart muscle is still alive and can recover. It is for people with severe blocked arteries and weak heart pumping function who are planning bypass surgery or stem cell treatment.
Shanghai, Shanghai MunicipalityAges Up to 80 years - NCT06711120Recruiting
Comparing two treatments for varicose veins in the lower legs
This study compares two minimally invasive treatments (radiofrequency ablation and microwave ablation) for varicose veins in the small saphenous vein. If your varicose veins cause symptoms like pain, swelling, or heaviness, this trial may help determine which treatment works better.
ChengduAges 18–90 - NCT05971225Recruiting
Testing remote heart monitoring to improve heart outcomes
This study checks whether starting remote wireless heart monitoring for people with heart failure helps improve important heart outcomes. It may help your care team catch warning signs earlier by receiving your heart data from home.
Suwon, Kyonggi DoAges 20 years+ - NCT05926271RecruitingPhase 2
Genotype-guided clopidogrel alone after stent placement
This trial looks at whether using clopidogrel by itself (without aspirin) works for people after a new drug-eluting stent, based on a blood test of how your body processes the drug. It may help reduce “extra blood-thinning” if you have a certain genetic type that responds well to clopidogrel.
Nieuwegein, UtrechtAges 18 years+ - NCT05986487Recruiting
Sleep apnea treatment for better blood pressure control
This trial tests whether treating sleep-disordered breathing (like sleep apnea) can help lower blood pressure in people with high blood pressure. You may join if you have high blood pressure and haven't been diagnosed with a sleep disorder before.
LleidaAges 18 years+ - NCT06168123Recruiting
Future care for aortic stenosis
This research study is a registry that collects information about people with aortic stenosis, a condition where a heart valve becomes narrow. The goal is to learn more about how this condition is managed and to improve future care.
NieuwegeinAges 18–110 - NCT06313684Recruiting
Hybrid cardiac rehab for heart failure patients
This study tests a hybrid cardiac rehab program (both at the clinic and at home) for people with heart failure. It combines supervised exercise sessions with remote support to help improve your heart health and daily function.
SantiagoAges 18 years+ - NCT06705023RecruitingPhase 2
Fat-derived cell therapy for heart failure
This study tests whether taking a small amount of your own belly fat (through liposuction), processing it, and injecting the cells back into your heart can improve heart function in people with chronic heart failure due to blocked arteries. The trial is for patients whose heart pumps weakly (ejection fraction of 40% or less) and who are already on standard medications.
AstanaAges 21–80 - NCT06713096Recruiting
Recovery plan for faster healing after bypass surgery
This trial tests a structured recovery plan to help people leave the hospital sooner after coronary artery bypass surgery. It may be a good fit if you are having planned or urgent bypass surgery and do not have severe heart or kidney problems.
São Paulo, São PauloAges Any age - NCT06713850Recruiting
Balloon treatment for leg artery blockages with calcium
This trial uses a special balloon (Shockwave IVL) to break up calcium in leg artery blockages, improving blood flow and reducing pain. It's for people with moderate to severe calcium buildup in the femoropopliteal artery.
Wuhan, HubeiAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.