Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT07609940RecruitingPhase 4
Linvoseltamab plus tocilizumab for heavily treated multiple myeloma
This trial tests a combination of two drugs (linvoseltamab and tocilizumab) for adults with multiple myeloma that has stopped responding to standard treatments. Tocilizumab is added to help reduce serious side effects from the main drug.
Los Angeles, CaliforniaAges 18 years+ - NCT05917717Recruiting
Test a care bundle for adults after witnessed cardiac arrest
This trial studies a “care bundle” approach using special devices to improve care after an out-of-hospital or witnessed cardiac arrest. It may help by standardizing emergency treatment for people right after their heart stops.
Southampton, EnglandAges 18–120 - NCT04666454RecruitingPhase 4
Medication trial for broken heart (Takotsubo) syndrome
This trial tests an optimized medication approach for people diagnosed with Takotsubo (“broken heart”) syndrome. It may help clinicians find a safer and more effective treatment plan after this heart condition.
AarhusAges 18 years+ - NCT04939207Recruiting
Test safer, cheaper scans for suspected coronary artery disease
This study compares new imaging methods to see how well they work and whether they can lower costs for people with suspected coronary artery disease. It may help by using different scan approaches while keeping patient safety in mind.
Eindhoven, North BrabantAges 18 years+ - NCT06224426Recruiting
Oxygen Levels for Stroke Patients Having Clot Removal
This trial tests whether giving a specific level of oxygen during a procedure to remove a stroke clot improves recovery. It is for people with a moderate to severe stroke in the front part of the brain, treated within 24 hours of symptoms starting.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07610538Recruiting
Low-dose IL-2 study after heart bypass surgery
This study tests whether a low dose of a natural immune-boosting protein (IL-2) given after heart bypass surgery can help reduce heart damage. The treatment aims to activate special immune cells that protect heart tissue.
Cambridge, CambridgeshireAges 18 years+ - NCT07611136Recruiting
Brain Vessel Disease Progression After Different Stroke Types
This study examines how small blood vessel disease in the brain progresses differently depending on whether you've had a recent stroke. Researchers will use MRI scans to track changes over time and better understand this condition.
Ulm, Baden-WurttembergAges 18 years+ - NCT07607275RecruitingPhase 4
Chinese herbal medicine for managing high blood pressure
This trial tests whether a traditional Chinese herbal medicine called Yufeng Ningxin can help lower blood pressure in adults with newly diagnosed or ongoing high blood pressure. Researchers will measure how well it works compared to standard treatment.
BeijingAges 18–65 - NCT07611019Enrolling by invitationPhase 2/Phase 3
Colchicine to prevent heart rhythm problems after heart bypass surgery
This study tests whether taking colchicine (a common anti-inflammatory medication) before and after bypass heart surgery can prevent atrial fibrillation—an irregular heartbeat that sometimes occurs after surgery. Researchers hope this simple treatment might reduce complications and improve recovery.
TaipeiAges 20 years+ - NCT07609966Recruiting
Virtual Reality for Stroke Arm Recovery
This trial tests whether virtual reality exercises help stroke patients recover arm and hand movement faster and better. You'd use VR games alongside your regular rehabilitation therapy in the hospital and after going home.
GironaAges 18 years+ - NCT07608926Recruiting
Heart Health Management: Digital Tools vs. Traditional Care
This study compares a new way to manage heart disease risk factors using digital technology (like apps or remote monitoring) with the traditional doctor visit approach. It aims to see which method better helps people control high blood pressure, blood sugar, cholesterol, and weight over 2 years.
Cotignola, RavennaAges 40–75 - NCT07607093Recruiting
Early rhythm control for atrial fibrillation with tricuspid valve leakage
This trial tests whether treating atrial fibrillation (an irregular heartbeat) early helps patients who also have tricuspid regurgitation (leakage in a heart valve). Researchers want to see if controlling the heart rhythm early can improve outcomes for people with both conditions.
Seoul, SeoulAges Any age - NCT07604467Recruiting
Understanding Stem Cells in Takotsubo Heart Syndrome
This study examines how certain stem cells (CD34+ cells) may contribute to takotsubo syndrome, a temporary heart condition often triggered by stress. By understanding this connection, researchers hope to improve treatment and recovery for patients with this condition.
Ljubljana, LjubljanaAges 18 years+ - NCT07606807RecruitingPhase 3
New clot-busting medication for stroke in the extended time window
This trial tests a new medication called rhTNK-tPA for treating acute ischemic stroke (a clot in the brain) up to 24 hours after symptom onset. The study uses simplified imaging to determine eligibility and aims to help patients recover better outcomes.
GuangzhouAges 18 years+ - NCT07605715Recruiting
Catheter vs. Surgery for Leaky Mitral Valve
This study compares two ways to fix a leaky mitral valve (a heart valve that doesn't close properly): one using a thin tube inserted through blood vessels (catheter) versus traditional open-heart surgery. The goal is to see which approach works better and is safer for older adults.
Los Angeles, CaliforniaAges 60 years+ - NCT07607795Recruiting
Grip Exercise and Blood Pressure in Pregnancy
This study tests whether a simple hand-squeezing exercise can help lower blood pressure in pregnant women. You'll either have high blood pressure before pregnancy or normal blood pressure, and researchers will see if regular grip exercises help manage it safely.
PoitiersAges 18–45 - NCT07604402Recruiting
Aortic Valve Replacement Without On-Site Surgery
This study tests a catheter-based procedure to replace a narrowed aortic valve without traditional open-heart surgery. It's designed for patients who are at higher risk for surgery due to age, health conditions, or anatomy.
AndriaAges Any age - NCT07604181Recruiting
Telerehabilitation vs clinic therapy for stroke arm recovery
This trial compares two ways of helping stroke survivors regain arm and hand function: therapy done remotely online versus in-person at a clinic. Both use a specialized approach called constraint-induced movement therapy, which encourages use of the weaker arm. The study aims to see which method works better for people in the first 6 months after stroke.
Faisalabad, Punjab ProvinceAges 40–70 - NCT07604103RecruitingPhase 3
Heart Attack and Pneumonia Recovery Study With Vaccination
This study looks at blood markers (special proteins) in patients who have had both a heart attack and pneumonia, to see how vaccination affects recovery. The goal is to understand whether flu and pneumonia vaccines are safe and helpful for people recovering from these two serious conditions together.
Malang, East JavaAges 18–65 - NCT07606768Enrolling by invitation
Nurse coaching to help control high blood pressure
This study tests whether regular phone or video coaching from a nurse helps people with high blood pressure better manage their condition and take their medications. You'll receive personalized guidance to improve your health habits and blood pressure control.
Huayuan, HunanAges 18–85 - NCT07606859Recruiting
Heat and Air Pollution Reduction for Older Adults With High Blood Pressure
This study tests whether reducing exposure to heat and air pollution helps older adults with high blood pressure feel better and stay healthier. Researchers will provide tools and support to help you stay cool and breathe cleaner air at home.
NicosiaAges 65 years+ - NCT07611968Recruiting
Physician-Modified Stent Grafts for Aortic Aneurysms
This trial tests a custom-made stent graft (a tube that reinforces the aorta from inside) for patients with large aortic aneurysms who may be too sick for traditional open surgery. The goal is to prevent rupture and complications while avoiding major surgery.
Jacksonville, FloridaAges 50 years+ - NCT07603648Recruiting
How different pacemaker lead positions affect heart rhythm signals
This study looks at how placing a pacemaker lead (a thin wire) in different spots in the upper heart chamber affects electrical signals. It may help doctors choose the best position for future pacemakers.
Zunyi, GuizhouAges 18 years+ - NCT07611045Recruiting
Understanding recovery and care after heart surgery
This study asks patients and their families about their experience after heart surgery (like bypass or valve repair) to help doctors improve follow-up care. You'll share your story through an interview, and your feedback could help future patients.
Bristol, BristolAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.