Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,982 recruiting studies in this area right now.
By phase
- Not applicable7,958
- Phase 2482
- Phase 4481
- Phase 3449
- Phase 1361
- Phase 1/Phase 2164
- Phase 2/Phase 387
Top conditions
- Stroke841
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Myocardial Infarction100
- Pulmonary Hypertension100
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas117
Recruiting studies9,979 total
- NCT07733960Recruiting
Pacing system study for heart pacing therapy
This trial tests a new pacing system designed to improve how pacemakers work. It may help people who need a pacemaker with left bundle branch area pacing.
Madurai, Tamil NaduAges 18 years+ - NCT03581318Recruiting
Heart MRI study for people with and without heart disease
This study uses magnetic resonance imaging (MRI) to take detailed pictures of the heart. It aims to improve how doctors use heart MRI to diagnose and manage heart conditions.
Bethesda, MarylandAges 7–100 - NCT07734584Recruiting
Reducing air bubbles during aortic repair with carbon dioxide
This trial tests a special flushing method using carbon dioxide gas to prevent air bubbles from entering the bloodstream during a procedure to fix the main artery in the chest. This could help avoid strokes or other complications.
Bologna, ItalyAges 18 years+ - NCT07730879Recruiting
Wall Squat Exercise for Blood Pressure in Sleep Apnea
This study tests whether a simple wall squat exercise can help lower blood pressure in people who have both high blood pressure and sleep apnea (treated with CPAP). If you are using CPAP regularly and are otherwise healthy enough to exercise, this trial may be a good fit for you.
BragaAges 18–80 - NCT07078370Enrolling by invitation
Testing a lab-made blood vessel for heart bypass surgery
This trial tests a lab-made blood vessel (called an ATEV) used as a bypass graft during heart surgery. The ATEV is designed for people who don't have enough healthy leg vein for standard bypass grafts, and it may help restore blood flow to the heart more safely.
PoznanAges 45–75 - NCT07695701RecruitingPhase 4
Heart imaging study for a new ATTR-CM treatment
This trial uses heart scans to see how the drug acoramidis affects heart structure and function in people with a specific type of heart disease called ATTR cardiomyopathy. It may help doctors understand if the treatment is working.
St Louis, MissouriAges 18–80 - NCT07450911RecruitingPhase 1
Mitral valve replacement with the ReValve system
This study is for people with severe mitral valve leakage (mitral regurgitation) who may need a valve replacement. It tests whether the ReValve system is safe and can help improve symptoms and heart function.
TbilisiAges 18 years+ - NCT05851391RecruitingPhase 2
Test drug treatment to stop hard-to-control seizures after cardiac arrest
This Phase 2 trial tests a medication strategy to stop “refractory status epilepticus,” a severe seizure condition that can happen after a cardiac arrest. It may help by reducing ongoing seizure activity after return of circulation in the ICU.
San Francisco, CaliforniaAges 18 years+ - NCT06638944RecruitingPhase 2
Wearable device training for swallowing after stroke or Parkinson's
This study tests a wearable device that gives feedback on swallowing exercises. It may improve swallowing safety after a stroke or for people with Parkinson's disease.
Champaign, IllinoisAges 50–90 - NCT07660263Recruiting
Predicting dementia after stroke with genetics and imaging
This study aims to develop a tool that predicts the risk of dementia after a stroke using genetic and imaging data. It enrolls both healthy adults and people who have had a stroke in the last 3 years.
Gyeonggi-do, Gyeonggi-doAges 19 years+ - NCT06871683Enrolling by invitation
Survey of ClotTriever device use in Japan
This trial is a survey that will collect information on all patients in Japan who are treated with the ClotTriever Thrombectomy System, a device used to remove blood clots. The goal is to understand how the device is used and how patients do in real-world practice.
Chuo, ChibaAges Any age - NCT07083986Enrolling by invitation
Surgery vs stenting for recent stroke patients
This trial compares two procedures to open a blocked carotid artery in people who recently had a stroke. One option is surgery (carotid endarterectomy) to remove the blockage, the other is stenting (placing a small mesh tube to hold the artery open). The goal is to see which works better for patients still having some stroke symptoms.
MoscowAges 18 years+ - NCT02316314Recruiting
Study heart scan and function in people with Friedreich’s ataxia
This study uses heart tests (including ultrasound and MRI) to better understand how Friedreich’s ataxia affects the heart. You might benefit by getting detailed heart evaluation and contributing to research that could guide future care.
New York, New YorkAges 12–50 - NCT03716167Recruiting
Near-infrared laser for healing and pain in leg vein ulcers
This study tests whether a near-infrared laser can improve healing and reduce pain in chronic venous leg ulcers. If you qualify, you may receive laser treatment and will be checked over time for wound healing and pain levels.
Winston-Salem, North CarolinaAges 18 years+ - NCT07704840RecruitingPhase 2
Testing a new pill for post-stroke arm stiffness
This study tests an experimental pill (BMS-986368) that targets two brain chemicals to reduce muscle stiffness after a stroke. It's for people who had a stroke in the last 4 to 18 months and have moderate tightness in their elbow and wrist.
Elkins Park, PennsylvaniaAges 18–80 - NCT07350798Recruiting
Using robots and virtual reality for stroke rehab on a treadmill
This trial tests whether robotic devices, virtual reality, or augmented reality can improve walking and balance during treadmill training for people who have had a single stroke. It aims to make rehab more engaging and effective.
Kaposvár, Somogy CountyAges 18–99 - NCT04840602RecruitingPhase 2
Venetoclax plus rituximab versus standard Waldenstrom treatment
This trial tests whether adding venetoclax to rituximab works better than standard treatment options for Waldenstrom’s macroglobulinemia (WM). It’s for adults whose WM needs treatment and who meet specific blood, organ, infection, and medication safety requirements.
Tucson, ArizonaAges 18 years+ - NCT07599579Recruiting
Mobile app to manage high blood pressure after pregnancy complications
This study tests a smartphone app to help women who had high blood pressure during pregnancy manage their blood pressure now, 10–20 years later. The goal is to see if the app helps keep blood pressure under control and reduces heart disease risk.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06401707RecruitingPhase 2
Seizure prevention after cardiac arrest
This study tests a seizure-prevention medicine called perampanel for people whose hearts stopped beating (cardiac arrest) and are now in the ICU. The goal is to see if it helps prevent seizures that can happen after such an event.
San Francisco, CaliforniaAges 18 years+ - NCT07084012RecruitingPhase 2
Stem cell treatment for recent stroke
This trial tests whether a single infusion of umbilical cord stem cells can help people recover from a recent ischemic stroke (stroke caused by a clot). It is for patients who have had their stroke within the last 72 hours and have moderate to severe symptoms.
Beijing, Beijing MunicipalityAges 18–75 - NCT03945305Recruiting
Remote ischemic conditioning for high blood pressure
This trial tests if a simple, non-invasive treatment called remote ischemic conditioning (briefly restricting blood flow to an arm) can safely lower blood pressure in people with essential hypertension. It is for adults aged 30-75 whose blood pressure is consistently high despite standard care.
Changchun, JilinAges 30–75 - NCT07731490Recruiting
Early detection and treatment of heart failure
This trial tests if a medication can prevent heart failure in older adults who are at risk. It is for people aged 65 or older who are having certain heart procedures or a major surgery.
ViennaAges 65 years+ - NCT05283356RecruitingPhase 4
Ticagrelor or aspirin after heart valve replacement
This trial compares two blood thinners (ticagrelor and aspirin) to see which one works better at preventing blood clots after a less-invasive heart valve replacement (TAVI). It is for people with severe aortic stenosis who also have diabetes, heart disease, or artery disease.
Vigo, PontevedraAges 18 years+ - NCT07732244Recruiting
Testing a wireless brain oxygen monitor in the NICU
This study is testing a new wireless device that monitors oxygen levels in the brain. It is for babies already using a similar wired monitor, to see if the wireless version works just as well.
Montreal, QuebecAges Any age
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,982 recruiting cardiology studies from the U.S. registry right now, out of 15,245 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.