Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,982 recruiting studies in this area right now.
By phase
- Not applicable7,962
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke844
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California465
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas118
Recruiting studies9,979 total
- NCT03562169RecruitingPhase 3
Ixazomib with your own stem cell transplant for relapsed myeloma
This trial studies whether adding ixazomib (an oral drug) to a transplant using your own stem cells can control relapsed multiple myeloma better. It may help by strengthening anti-myeloma treatment after the transplant, aiming to delay disease progression.
AberdeenAges 18 years+ - NCT03563417Recruiting
CTO treatment vs medicines after heart scan
This trial studies whether opening a blocked coronary artery (a CTO) helps people more than staying on the best available heart medicines after an initial 3-month treatment period. It uses heart imaging to confirm there is reduced blood flow in the area supplied by the blockage.
Aarhus NAges 18 years+ - NCT03569735Recruiting
Elderly health survey in Nanshan, Shenzhen
This study follows people age 65 and older in Nanshan to learn about health over time using surveys and health samples. It may help researchers understand what supports healthy aging in the community.
Shenzhen, GuangdongAges 65 years+ - NCT03570450RecruitingPhase 1
Stem cell treatment for non-lacunar stroke after the first day
This early-phase study tests a stem cell treatment for certain types of stroke, focusing first on safety and the right dose. It may help doctors learn whether the treatment is safe and potentially beneficial when given soon after stroke begins.
GrenobleAges 18 years+ - NCT03571763Recruiting
Anti-clotting treatment study in stroke patients with small brain bleeds
This trial looks at how anti-clotting medicines affect small blood vessel bleeds in the brain (cerebral microbleeds) and larger bleeding in the skull after an ischemic stroke. It may help doctors choose safer prevention medicines for people who already have these small bleeds seen on brain MRI.
ShenyangAges 18 years+ - NCT03582293RecruitingPhase 3
Tranexamic acid to prevent worsening chronic brain bleed
This Phase 3 study tests whether tranexamic acid (a medicine that helps blood clot) can stop a chronic subdural hematoma from getting worse. It’s for people diagnosed by CT who are being treated without surgery at first.
AmsterdamAges 50 years+ - NCT03586518Recruiting
Non-contrast heart MRI test in dialysis patients
This trial checks whether a new kind of heart MRI (done without contrast dye) can help doctors see heart changes in people receiving hemodialysis. It may help improve how heart health is measured in dialysis care, especially for people with limited time.
Leicester, LeicestershireAges 18 years+ - NCT03586258Recruiting
Brain scan and memory testing for people with brain injury
This study uses memory and thinking tests along with brain scans (likely MRI) to understand how different types of brain damage affect thinking. It may help doctors learn more about brain-related cognitive problems.
CaenAges 18 years+ - NCT03587922Recruiting
Test a dissolving heart stent for blocked heart arteries
This study tests a dissolving scaffold (a type of temporary heart stent) in people with narrowed coronary arteries that are causing reduced blood flow. It aims to see if the device can be safely used as part of planned stenting or emergency bypass when needed.
ViennaAges 18 years+ - NCT03588286Recruiting
Check heart rhythm risk early after a heart attack
This trial tests whether a programmed heart rhythm test can better identify who needs an implanted defibrillator (ICD) soon after a heart attack. It may help prevent dangerous fast heart rhythms (tachyarrhythmias) by guiding who gets an ICD.
Boston, MassachusettsAges 18–85 - NCT03588481Recruiting
Check DeSyne X2 coronary stent in a heart registry
This study adds people to a registry to track outcomes after getting a specific heart stent called DeSyne X2. It may help doctors understand how well this stent works and how it affects recovery over time.
IncheonAges 19 years+ - NCT03592563Recruiting
Brain health follow-up study for adults
This study follows adults over time to better understand brain health and brain-related conditions. You may join if you already have certain neurological or psychiatric diagnoses, are at higher risk, or simply want to help research on maintaining brain health.
Hong KongAges 18 years+ - NCT03593317RecruitingPhase 2
Test medicine that blocks hormones for ARVD heart disease
This Phase 2 trial studies whether blocking certain heart/hormone signals can improve ARVD (a heart muscle condition). It also looks at safety by checking how well your kidneys and electrolytes tolerate these medicines.
AmiensAges 18 years+ - NCT03594344Recruiting
Extra hyperbaric oxygen after leg amputation wounds heal
This study tests whether giving extra treatments with hyperbaric (pressure) oxygen after a leg amputation can improve healing or recovery. It’s meant for people whose amputation happened due to long-lasting infection or poor blood flow and who can attend follow-up visits.
OsloAges 18–90 - NCT03594318Recruiting
Registry for adults treated in ICU after cardiac arrest
This trial is a registry, which means the researchers collect information about people who were treated in an intensive care unit after a cardiac arrest. It may help improve understanding of outcomes and care, which can guide future treatment.
Le ChesnayAges 18 years+ - NCT03595267Recruiting
Kidney health checks and care for Indigenous communities
This study offers kidney-related health screening and follow-up care for people in Indigenous communities. It’s designed to help check kidney health early using simple health measurements, and may help you get guidance sooner if anything looks off.
Calgary, AlbertaAges 10–80 - NCT03600662Recruiting
Heart valve reconstruction using your own tissue
This trial studies a surgery to repair the aortic valve using tissue taken from your body. It may help people with significant valve problems, by testing whether this reconstruction approach works and is safe.
Munich, BavariaAges 50 years+ - NCT03601702Recruiting
EmboTrap device for large stroke blockages
This trial studies whether a specific clot-removal device (EmboTrap II) works well for acute stroke caused by a large artery blockage. It may help restore blood flow faster in people who have certain scan patterns and can be treated within 12 hours.
MilanAges 18 years+ - NCT03604133Recruiting
Registry for people getting a defibrillator implanted in a clinic
This trial is a registry that collects information about outcomes after getting an implantable cardioverter-defibrillator (a device that can help correct dangerous heart rhythms). You may be invited if your doctor recommends the implant to be done at an ambulatory surgical center (a same-day surgery clinic).
Lehi, UtahAges Any age - NCT03606200Recruiting
Join a registry for primary ciliary dyskinesia
This study is a registry that collects information from people diagnosed with primary ciliary dyskinesia. It may help researchers better understand the condition over time and improve future care.
BernAges Any age - NCT03607565Recruiting
Imaging test to measure brain blood flow in stroke
This trial studies a new imaging measurement derived from DSA (a special type of brain blood-vessel scan) to better estimate how well blood is flowing in the brain. It may help doctors assess stroke-related blood-flow problems, but it excludes people who have brain bleeding.
Xi'an, ShaanxiAges Any age - NCT03611816Recruiting
Biobank study for atrial fibrillation and stroke samples
This study collects and stores medical information and biological samples from people with atrial fibrillation (or certain types of stroke). It helps researchers better understand these conditions and may support future improvements in diagnosis or treatment.
Bourg-en-BresseAges 18 years+ - NCT03616483Recruiting
Indiana Myeloma Registry for blood cancer-related diagnoses
This registry collects information from adults with certain plasma-cell conditions like MGUS, smoldering multiple myeloma, multiple myeloma, plasmacytoma, or primary amyloidosis. It may help researchers learn more about these diseases and improve future care.
Indianapolis, IndianaAges 18 years+ - NCT03622359Recruiting
Imaging blood flow in leg artery disease using a scan
This study uses a special “radiotracer” scan to look at how well blood flows through the arteries in the legs. It may help researchers better understand circulation problems from peripheral artery disease.
Columbus, OhioAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,982 recruiting cardiology studies from the U.S. registry right now, out of 15,268 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
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- Pain
- Injuries & trauma
- Mouth & dental
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.