Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT07551141Recruiting
Vibration to Help Stroke Recovery: Balance and Walking
This study tests whether vibrations applied to the bottom of your feet can help improve walking and balance after stroke. You'll receive plantar vibration therapy (gentle vibrations under your feet) while performing walking and balance exercises to see if it helps your recovery.
BoluAges 18–75 - NCT07548099Recruiting
PET scan study of aorta inflammation in aneurysm patients
This research uses a special imaging scan (PET/CT) to take detailed pictures of inflammation in the aorta (the main blood vessel from your heart). Researchers want to understand why some people develop bulges in their aorta called aneurysms. If you have an aneurysm or are a healthy volunteer, this study may help improve how doctors detect and treat this condition.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06654401Recruiting
Using electrical shock to restore normal heart rhythm after surgery
This study looks at whether giving an electrical shock (cardioversion) right after heart surgery can help people with long-lasting atrial fibrillation keep a normal heartbeat. It may help guide future treatment decisions for patients who have not gotten better with medication.
Saint Petersburg, Sankt-PeterburgAges 18 years+ - NCT06744361RecruitingPhase 2
Ketamine after cardiac arrest to protect the brain
This trial tests whether the sedative drug ketamine, given after a cardiac arrest, can help protect the brain. It's for people whose heart stopped outside the hospital due to a shockable rhythm and who needed a breathing tube placed by emergency responders.
CopenhagenAges 18 years+ - NCT06743568Recruiting
Comparing new valves for tight aortic valve in enlarged aorta
This trial tests two types of replacement heart valves (self-expanding and balloon-expanding) in people who have severe aortic stenosis (tight heart valve) and an enlarged aorta (the main blood vessel from the heart). The goal is to see which valve type works better for these patients.
Beijing, Beijing MunicipalityAges 65 years+ - NCT06739239Recruiting
French cohort study of an extra-vascular ICD
This study follows patients who receive a new type of implantable defibrillator that sits outside the heart and blood vessels. It aims to collect information about how well the device works and how safe it is over time.
ParisAges Any age - NCT04921501Recruiting
Testing a detailed heart tracing to evaluate rhythm risks
This study checks a more detailed kind of heart recording (ECG) using many small sensors to better measure electrical rhythm problems. It may help doctors refine how they assess risk in people with serious or suspected dangerous heart rhythm issues.
Clermont-FerrandAges 14 years+ - NCT04196712Recruiting
Heart artery testing registry during coronary angiography
This trial is a registry that collects information from people undergoing an invasive heart artery test (coronary angiography). It helps researchers understand heart disease and outcomes in real-world patients.
Essen, North Rhine-WestphaliaAges Any age - NCT05640752Recruiting
Testing whether better heart imaging planning reduces scans
This trial studies the best way to decide when people need heart imaging tests, with the goal of doing fewer unnecessary scans. It may help patients by avoiding extra radiation and tests while still keeping care safe and appropriate.
Beijing, Beijing MunicipalityAges 30–90 - NCT06746532RecruitingEarly Phase 1
Breast milk nose drops for brain injury in newborns
This trial tests whether giving fresh breast milk as nose drops can help newborns with brain injury from lack of oxygen. It aims to see if this simple treatment can improve brain recovery.
BudapestAges Up to 2 days - NCT06016608Recruiting
Polyvascular disease imaging study
This study uses a special camera to take detailed pictures of artery blockages in people with heart disease, stroke, or mini-stroke. It may help doctors better understand how to treat multiple blocked arteries.
Harbin, HeilongjiangAges 18 years+ - NCT06359782RecruitingPhase 2
Testing C1-inhibitor for brain bleed after aneurysm
This trial tests a drug called C1-inhibitor (a protein that calms inflammation) given shortly after a bleeding stroke caused by an aneurysm. The goal is to see if it can reduce brain damage and improve recovery.
The Hague, South HollandAges 18 years+ - NCT06271187Recruiting
Brace Therapy for Hand Recovery After Stroke
This study tests whether a custom brace (dynamic orthosis) combined with therapy can improve hand movement in people who had a stroke at least 3 months ago. It is designed for those whose arm has some recovery but still needs help with hand opening and grasping.
TainanAges 20–80 - NCT06124664Recruiting
Study of leg vein drainage in pelvic varicose veins
This study looks at how blood flows from the legs in people with varicose veins in the pelvis. It may help doctors understand the link between pelvic and leg vein problems.
MoskvaAges 18–40 - NCT06459388Recruiting
Balance training methods for stroke recovery
This study compares two types of physical therapy exercises to help stroke survivors improve balance and walking. One method uses arm and leg movements, while the other focuses on the pelvis area.
Lahore, Punjab ProvinceAges 40–65 - NCT06407830Recruiting
Walking therapy with and without muscle stimulation for stroke recovery
This study tests whether adding electrical muscle stimulation to a walking and movement program helps stroke survivors walk better, become more independent, and improve their quality of life.
Lahore, Punjab ProvinceAges 45–65 - NCT07539324Recruiting
Drug-coated balloon vs stent for multiple blocked heart arteries
This study compares two treatments for people with blockages in more than one heart artery. One treatment uses a drug-coated balloon to open the artery, and the other uses a drug-releasing stent. The goal is to see which approach is safer and works better.
UlsanAges 20 years+ - NCT07541833Recruiting
Mavacamten Treatment Patterns in Obstructive Heart Thickening
This study tracks how mavacamten (a heart medication) works in Japanese patients with obstructive hypertrophic cardiomyopathy—a condition where the heart muscle becomes abnormally thick and blocks blood flow. The trial aims to understand how well the treatment works and how doctors use it in real-world care.
Minato-ku, TokyoAges 18 years+ - NCT07541404Recruiting
NeoCast embolization for subdural hematoma treatment
This trial tests a newer way to treat subdural hematoma—a bleeding problem inside the brain. After surgery to drain the blood, you'll receive an additional minimally invasive procedure (middle meningeal artery embolization) using a new device called NeoCast to help prevent the bleeding from coming back.
New Haven, ConnecticutAges 18–90 - NCT07540507Recruiting
Data collection for branched aortic stent grafts
This trial collects follow-up data from patients who received special branched stent grafts (tube-like devices) to treat complex aortic aneurysms (weakened areas of the main blood vessel). The study helps confirm these devices work safely over time.
HeerlenAges 18 years+ - NCT06542653Recruiting
PCI for chronic heart artery blockages
This trial looks at how a procedure to open a long-clogged heart artery (called PCI) affects patients' long-term health. If you have had a complete blockage in a heart artery but no recent major heart attack, bypass surgery, or cancer, you may be able to join.
Nanjing, JiangsuAges 18–75 - NCT06674980Recruiting
Testing placenta-based wound treatment for diabetic and venous leg ulcers
This trial tests if adding a special placenta-based wound covering to standard care helps heal diabetic foot ulcers and venous leg ulcers faster. It's for people with wounds that haven't healed after standard treatment for at least 4 weeks.
Metairie, LouisianaAges 18 years+ - NCT06690593Recruiting
Gut Microbiome Study for Healthy Adults Age 45+
This study compares the gut bacteria of healthy adults (age 45+) with those who have a blood condition called monoclonal gammopathy. The goal is to see if gut bacteria patterns differ between the two groups.
Guanzhou, GuangdongAges 45 years+ - NCT07541118Recruiting
Boosting physical activity for kids and teachers
This study tests a program to help elementary school students and teachers get more physical activity, which may lower heart disease risks.
Houston, TexasAges 5 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.