Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT05829889Recruiting
FFR test versus angiogram to guide left main heart treatment
This trial compares two ways to decide how to treat a narrowed “left main” coronary artery: a pressure-based test (FFR) versus standard X-ray imaging (angiography). It aims to see which approach better helps choose safe, appropriate treatment using a stent when appropriate.
Hong KongAges 20 years+ - NCT05829993Recruiting
AI program to spot ECG heart rhythm risk
This study tests an artificial intelligence (computer) tool that looks at your ECG (heart tracing) to help detect abnormal heart electrical patterns and the risk of dangerous rhythm problems. You may be helping clinicians screen for rhythm risk using ECG data.
ParisAges 18 years+ - NCT05830305Recruiting
Phone app coaching after brain bleed to help blood pressure
This trial tests a mobile health app (WeRISE) to help people who survived an intracerebral hemorrhage (a type of brain bleed) monitor health and manage blood pressure after discharge. It may help you reduce the risk of problems related to high or unstable blood pressure.
Hong KongAges 18–85 - NCT05830721Recruiting
Monitoring leg pressure in adults on life-support
This trial tests a device that continuously measures pressure in an arm or leg to help detect compartment syndrome in people on a heart-lung machine (VA-ECMO). It may help clinicians act sooner if pressure becomes dangerous, potentially reducing complications.
Baltimore, MarylandAges 18 years+ - NCT05831085Recruiting
Compare procedures to improve heart blood flow in diabetes
This study compares two ways to restore blood flow to the heart—stent placement (PCI) versus bypass surgery (CABG)—in people with diabetes and significant multi-vessel coronary artery disease. It looks at outcomes using both standard heart tests and additional imaging/functional measurements to guide the best revascularization strategy.
Palo Alto, CaliforniaAges 20 years+ - NCT05832567Recruiting
Study of hidden and open placebo effects in stroke recovery
This study looks at how “open” (told) and “hidden” (not told) placebo effects may change arm recovery after a long-term stroke. You would do recovery-related assessments and likely receive brain-stimulation or related procedures to test these effects.
Cambridge, MassachusettsAges 18 years+ - NCT05832580RecruitingPhase 3
Preventing calcium buildup in skin, eyes, and blood vessels
This Phase 3 study tests a medicine to help prevent abnormal calcium (called ectopic mineralization) from building up in people with pseudoxanthoma elasticum (PXE). It aims to slow or reduce new damage over time.
UtrechtAges 18–50 - NCT05832762Recruiting
Clot-buster procedure for blocked neck artery stroke
This trial studies whether an emergency clot-removal procedure through the blood vessels (endovascular treatment) helps people who have a stroke caused by a blocked internal carotid artery in the neck. It compares outcomes in patients treated urgently when imaging shows the blockage is likely the main cause.
Montpellier, FanceAges 18 years+ - NCT05833828Recruiting
Testing blood-pressure hormone changes during bypass surgery
This study looks at how a blood-pressure hormone system (RAAS) changes during coronary artery bypass surgery. It may help researchers understand better how to manage blood pressure and heart stress around the time of surgery.
BerlinAges 18 years+ - NCT05833932Recruiting
Registry study of Suhexiang Pill after recent stroke
This study tracks people who had an ischemic stroke (a type of stroke caused by blocked blood flow) within the last week and received Suhexiang Pill. It aims to see how outcomes and follow-up go in real-world use, which may help doctors understand who might benefit and how to monitor patients.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05834803Recruiting
Stenting narrowed kidney artery to help high-risk patients
This trial studies whether placing a small stent in a severely narrowed kidney artery can improve outcomes for people with high-risk, artery-hardening kidney blood-flow problems. It focuses on people whose high blood pressure or kidney function has been getting worse despite multiple medications.
Aarhus NAges 18 years+ - NCT05836259RecruitingPhase 1/Phase 2
TN-201 for heart symptoms from MYBPC3 heart disease
This early trial tests TN-201 to see how safe it is and how well it works to reduce symptoms in adults with MYBPC3-related hypertrophic cardiomyopathy. It’s designed to learn safe dosing, and you may be eligible if you have specific genetic heart changes and ongoing symptoms.
La Jolla, CaliforniaAges 18–75 - NCT05835791Recruiting
Study of new ventricular arrhythmia patients getting ICD follow-up
This study looks at people who are newly diagnosed with a dangerous heart rhythm called ventricular tachycardia (VT) and who are getting an implantable cardioverter-defibrillator (ICD). It may help improve how patients are followed in the ICD clinic after the initial hospitalization.
Vancouver, British ColumbiaAges 18 years+ - NCT05836831RecruitingPhase 4
Tranexamic acid for sudden brain bleeding after stroke
This trial studies whether tranexamic acid (a medicine that helps blood clot) can improve outcomes after a spontaneous (not caused by injury) brain bleed. It is designed for adults who arrive soon after stroke symptoms start and meet several safety and timing requirements.
Guntur, Andhra PradeshAges 18–99 - NCT05836610RecruitingPhase 4
Testing hydrocortisone dosing during newborn cooling
This Phase 4 trial studies the best way to give hydrocortisone (a steroid medicine) to newborns who are being cooled for a specific kind of birth-related lack of oxygen. It’s for babies who have low blood pressure during cooling, aiming to improve their stability while they receive standard treatment.
Budapest, Pest CountyAges Up to 3 days - NCT05836896RecruitingPhase 1
Safety check of BCMA CAR T-cells made from your own immune cells
This early-phase trial tests whether a personalized BCMA-targeting CAR T-cell treatment is safe and what dose is tolerable in people whose lymphoma or myeloma has come back or did not respond to prior treatment. If you qualify, the team will monitor you closely for side effects to find the safest maximum tolerated dose.
DresdenAges 18 years+ - NCT05836987RecruitingPhase 3
Smartwatch monitoring trial to guide blood thinner use for AF
This study tests whether continuous heart-rhythm monitoring with a smartwatch can better guide treatment for atrial fibrillation (AF) while you stay on a blood thinner. The goal is to improve safety and reduce stroke risk by catching AF patterns more closely.
Phoenix, ArizonaAges 22–85 - NCT05838079Recruiting
Baby heart study for families affected by diabetes
This study looks at how diabetes during pregnancy affects children’s or babies’ heart health over time. It may help researchers understand risks early, especially for families with a diabetes history during pregnancy.
Copenhagen ØAges 1 day–99 years - NCT05838235Recruiting
Exercise program for kids with Marfan syndrome
This trial studies an adapted physical activity (exercise) program to support effort rehabilitation in children and teens with Marfan syndrome. It may help safely improve activity and fitness while monitoring heart-related risks.
ToulouseAges 7–17 - NCT05838547Recruiting
PET-MR scan study for narrowing in the carotid artery
This study tests how well a special PET-MR scan can help evaluate carotid artery plaque in people who have significant narrowing but no symptoms. It may help researchers better understand disease activity to guide treatment decisions like medication alone or medication plus surgery.
Los Angeles, CaliforniaAges 18 years+ - NCT05838950Recruiting
Short high-intensity exercise program for cardiometabolic health
This trial studies whether a structured, short high-intensity exercise program can improve health markers related to weight, blood sugar, and blood fats in young adults with obesity. It may help you see if this kind of exercise leads to measurable health improvements.
Syracuse, New YorkAges 18–25 - NCT05839067Recruiting
Support program for U.S. veterans living with heart failure
This trial supports U.S. Veterans who have heart failure, to see whether the added support improves health and well-being. You may be able to join if you meet the age, diagnosis, and communication requirements.
Gainesville, FloridaAges 18 years+ - NCT05839717Recruiting
Testing gene changes in PV or ET and blood clot risk
This study looks at a specific gene mutation in people with polycythemia vera (PV) or essential thrombocythemia (ET) to understand how it may relate to blood clots. It mainly involves collecting blood samples and joining a medical registry, before clot-lowering medicines start.
AngersAges 18 years+ - NCT05841199Recruiting
Study heart blood flow during fast heart rates
This study measures how well blood flows through the heart when the heart rate is increased during a heart procedure. It may help doctors better understand coronary (heart artery) blood flow and how to guide treatment when you need angiography or angioplasty.
LondonAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.