Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,609 recruiting studies in this area right now.
By phase
- Not applicable7,632
- Phase 4472
- Phase 2469
- Phase 3439
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke797
- Heart Failure534
- Hypertension388
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction97
- Congenital Heart Disease84
- Peripheral Arterial Disease79
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California453
- Alabama196
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois112
Recruiting studies9,609 total
- NCT05765370Recruiting
LDL cholesterol study in people 75+ with heart or blood vessel disease
This trial studies how to lower “bad” cholesterol (LDL) in people age 75 and older who have already had heart, brain, or leg/blood-vessel problems from blocked arteries. The goal is to see if the approach helps prevent further cardiovascular events (like heart attack or stroke).
Beijing, Beijing MunicipalityAges 75 years+ - NCT05322824Recruiting
Study for adults with narrowed brain or neck arteries
This study enrolls people age 40 or older who have at least 50% narrowing in one brain or neck (carotid) artery. It collects clinical information to better understand this condition and how patients are doing over time.
Hangzhou, ZhejiangAges 40 years+ - NCT05811780Recruiting
Record of devices that support organs outside the body
This registry collects information about people who are treated with a machine that supports an organ outside the body. The goal is to better understand how these devices are used and may help improve care over time.
Freiburg im BreisgauAges Any age - NCT05588583Recruiting
Tracking drainage from chronic leg or foot ulcers with a dressing
This study follows how much fluid (drainage) a chronic ulcer produces over time using a dressing called Mepilex Up. It may help clinicians better understand how this dressing manages “exuding” ulcers on the leg or foot.
Castro Valley, CaliforniaAges 18 years+ - NCT01653223Recruiting
Simvastatin to protect the heart during heart surgery
This trial looks at whether simvastatin (a cholesterol medicine) can help protect the heart during cardiac surgery. You might be invited if you’re having surgery for certain, non-complex heart conditions, but not if you have some specific related health problems.
Guangzhou, GuangdongAges 18 years+ - NCT05823519Recruiting
Follow-up study after Ovation repair for abdominal aneurysm
This trial studies people who need an endovascular repair for a type of abdominal aortic aneurysm using the Ovation Alto device. It looks at outcomes after treatment and shares study data with the research team, which may help improve care for future patients.
Palma de Mallorca, Balearic IslandsAges 18 years+ - NCT05832580RecruitingPhase 3
Preventing calcium buildup in skin, eyes, and blood vessels
This Phase 3 study tests a medicine to help prevent abnormal calcium (called ectopic mineralization) from building up in people with pseudoxanthoma elasticum (PXE). It aims to slow or reduce new damage over time.
UtrechtAges 18–50 - NCT05630586RecruitingPhase 2
Semaglutide shot for early stroke recovery
This Phase 2 study tests whether a semaglutide injection given under the skin soon after an acute ischemic stroke can improve recovery. It may help reduce disability, especially if treatment starts within about 4.5 hours of symptom onset.
AarhusAges 18 years+ - NCT05838079Recruiting
Baby heart study for families affected by diabetes
This study looks at how diabetes during pregnancy affects children’s or babies’ heart health over time. It may help researchers understand risks early, especially for families with a diabetes history during pregnancy.
Copenhagen ØAges 1 day–99 years - NCT02444416Recruiting
Registry study for people with new acute heart failure
This study is a registry that collects information about people who come to care with sudden (acute) worsening heart failure symptoms. If your test shows a higher BNP level, your doctors may use your details to better understand and track acute heart failure care.
GenevaAges 16–100 - NCT04737317Recruiting
Check criteria to diagnose cardiac sarcoidosis
This study tests how doctors can best tell whether someone has cardiac sarcoidosis, a condition where inflammation affects the heart. It may help you get a more accurate diagnosis using expert guidelines and special heart tests, and it groups patients as proven, probable, or unlikely.
LeipzigAges 18 years+ - NCT05727111Recruiting
Home therapy program for people with long-term stroke
This trial tests a structured therapy program done at home to help with movement after chronic stroke. It may help if you have lasting arm/hand problems and can follow simple instructions with a caregiver’s daily support.
BrusselsAges 18–100 - NCT05647876Recruiting
Study how menopause affects heart health risk over time
This study follows people through menopause to better understand how the body changes and how that may affect heart health risk. You may be asked for health checks over time, as researchers look for factors that increase or protect against heart problems.
CopenhagenAges 40–61 - NCT05853796Recruiting
Studying stroke warning signs in young adults
This observational study follows people ages 18–50 who had a first TIA (“mini-stroke”) or an acute ischemic stroke to better understand what happens after the event. It may help improve future care by tracking symptoms, imaging findings, and recovery over time.
Nijmegen, GelderlandAges 18–50 - NCT05561088Recruiting
Head acupuncture after stroke clot removal
This trial studies whether doing head acupuncture after a procedure to remove a stroke-causing blood clot can improve recovery and safety. You may be considered if you had endovascular clot removal within 24 hours and meet specific brain-scan and stroke-severity measures.
Xi'an, ShaanxiAges 18–100 - NCT03245866Recruiting
Study for bleeding caused by a brain aneurysm rupture
This study is for people admitted with a confirmed brain bleeding caused by a ruptured aneurysm. The goal is to better understand this specific cause of bleeding, which may help improve care for patients with aneurysm-related subarachnoid hemorrhage.
Aarau, Canton of AargauAges Any age - NCT04741711Recruiting
At-home ultrasound to help manage heart failure
This study tests whether using lung ultrasound at regular visits can help guide care for people with heart failure. It may help doctors spot worsening fluid problems earlier, before symptoms become severe.
BesançonAges 18 years+ - NCT03113552Recruiting
How mitral valve bulging location affects long-term repair outcomes
This study looks back at people who had mitral valve repair surgery to see whether the exact location of a valve problem predicts long-term results. It may help doctors better predict outcomes after surgery and plan follow-up care.
Amiens, PicardieAges 18 years+ - NCT04862507Recruiting
Thrombectomy treatment for severe stroke with low ASPECTS
This trial studies an approach for removing a blockage using thrombectomy in people with an acute ischemic stroke that shows a low ASPECTS score. It may help restore blood flow in strokes that have significant early changes on brain imaging.
BerlinAges 18 years+ - NCT03002272Recruiting
Long-term follow-up after TAVR or surgical valve replacement
This study checks how well an aortic valve replacement works many years after the procedure. It may help doctors understand long-term valve function and identify people who might need closer monitoring.
Washington D.C., District of ColumbiaAges 18 years+ - NCT04997824Recruiting
AI-guided selection for atrial fibrillation ablation
This trial tests whether an artificial intelligence (AI) system can help choose the best patients for a procedure called catheter ablation for atrial fibrillation (AF). It may improve which people benefit most while keeping safety in mind.
SeoulAges Any age - NCT05519735Recruiting
Heart MRI study after a heart attack treated by catheter
This study looks at the lymphatic system and heart tissue after a heart attack (STEMI) in people who had prompt catheter treatment. It uses heart MRI to understand healing and may help researchers improve care after a heart attack.
WürzburgAges 18–90 - NCT02900521Recruiting
Brest stroke and clot registry for local adults
This study is a population registry that records information from people in a specific area of Brest who had certain types of brain blood vessel events. It helps researchers understand how these conditions happen in the real world and may improve future care planning.
BrestAges 15 years+ - NCT05884892Recruiting
Join a heart condition registry for hypertrophic cardiomyopathy
This program builds a registry of people diagnosed with hypertrophic cardiomyopathy and their family members. By collecting health information over time, researchers hope to better understand the condition and improve care.
AswānAges Any age
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,609 recruiting cardiology studies from the U.S. registry right now, out of 14,617 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.