Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,976 recruiting studies in this area right now.
By phase
- Not applicable7,959
- Phase 2483
- Phase 4479
- Phase 3447
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 386
Top conditions
- Stroke841
- Heart Failure567
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma334
- Atrial Fibrillation268
- Ischemic Stroke201
- Atrial Fibrillation (AF)140
- Acute Ischemic Stroke137
- Myocardial Infarction102
- Pulmonary Hypertension100
- Congenital Heart Disease85
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California460
- Alabama197
- Massachusetts183
- Arizona174
- New York161
- Florida145
- Maryland120
- Illinois119
- Minnesota119
- Texas118
Recruiting studies9,973 total
- NCT06557798Recruiting
Second TAVI for failing aortic valve replacement
This trial is for people who have already had a TAVI (a minimally invasive aortic valve replacement) and now need a second procedure because the valve is failing. The study will test how well a redo TAVI works to fix the failing valve.
AalborgAges 18 years+ - NCT06209723Recruiting
Vegetarian diet study for recent heart attack patients and their partners
This study tests whether a vegetarian diet can help the immune system recover after a heart attack. It is for people who recently had a heart attack and their healthy partners.
NijmegenAges 18 years+ - NCT07179380RecruitingPhase 3
A study of an inhaled drug for lung disease with high blood pressure
This trial tests an inhaled medicine (TPIP) for people with both lung scarring (interstitial lung disease) and high blood pressure in the lungs (pulmonary hypertension). It aims to see if the drug helps improve exercise ability and symptoms.
Los Angeles, CaliforniaAges 18 years+ - NCT07763340Recruiting
Photon-counting ct heart scan for people with coronary stents
This study tests a new type of CT scan that takes very detailed pictures of the heart and stents. It may help doctors see whether stents remain open and guide future care.
Beijing, Beijing MunicipalityAges 18–100 - NCT07764081Recruiting
Coronary artery aneurysm care and outcomes
This study looks at how coronary artery aneurysms (a bulging or ballooning of the heart's blood vessel wall) are managed and how they affect people over time. It aims to improve future care by tracking treatment and health results.
Nanjing, JiangsuAges 18–80 - NCT07763054Recruiting
Low-dose antifungal prevention for patients with low white blood cell counts
This trial tests a low dose of an antifungal medicine (liposomal amphotericin B) to prevent fungal infections in patients whose white blood cell counts are very low for more than a week. It may help patients who are at high risk for fungal infections and cannot take other antifungal drugs.
Hainan, HainanAges 18–75 - NCT07764172Recruiting
Sarcopenia in acute ischemic stroke
This study looks at muscle loss (sarcopenia) in people who have had an acute ischemic stroke. It aims to understand how muscle wasting affects recovery, which may help improve care for stroke patients.
MoscowAges 50 years+ - NCT06622005RecruitingPhase 1
Combination treatment for multiple myeloma that has returned
This trial tests a new drug (SX-682) added to a standard three-drug combination (carfilzomib, daratumumab, and dexamethasone) for people whose multiple myeloma has come back or stopped responding to previous treatment. The goal is to see if adding this drug helps control the cancer better.
Buffalo, New YorkAges 18 years+ - NCT07577336Recruiting
Portable MRI for brain injury in children
This study tests whether a small, portable MRI machine can take pictures of the brain at the bedside for children with brain injuries from lack of oxygen or blood flow. It may help doctors see the injury sooner and guide care without moving the child.
Kansas City, MissouriAges Up to 17 years - NCT07762222Recruiting
Iliac vein stenting for chronic post-thrombotic venous ulcers
This trial tests whether placing a stent (a small mesh tube) in the iliac vein can help heal chronic leg ulcers caused by prior blood clots. The goal is to improve blood flow and reduce symptoms.
CairoAges 18–70 - NCT07371624RecruitingPhase 1/Phase 2
Study of B2065 for recent ischemic stroke
This trial tests an investigational drug called B2065 for people who have had a recent ischemic stroke (a stroke caused by a blockage in a blood vessel in the brain). The goal is to see if it is safe and if it might help improve recovery when given within 36 hours of stroke symptoms starting.
BeijingAges 18–75 - NCT07262255Recruiting
Watchman FLX Pro heart device study in Europe
This study tracks people with atrial fibrillation (an irregular heartbeat) who get the WATCHMAN FLX Pro device to reduce stroke risk. It collects real-world data on how well the device works and how safe it is.
AarhusAges 18 years+ - NCT07693348Recruiting
Daily stair climbing for heart rehab
This trial tests whether climbing stairs every day helps people with heart problems recover better during cardiac rehab. If you are in a rehab program and can walk without help, you may be able to participate.
ArrasAges 18 years+ - NCT03372733RecruitingPhase 2
Omega-7 oil effects on blood fats and fullness
This study tests whether an omega-7 (palmitoleic acid–rich) oil changes your blood fat levels and how full you feel. It includes healthy adults and may help explain nutrition-based ways to support heart health.
Bethesda, MarylandAges 18–99 - NCT06826755Recruiting
Melatonin for heart health in midlife women
This study tests whether melatonin can help improve heart health in midlife women with high blood pressure. It involves taking a melatonin pill or placebo for several weeks and checking blood pressure and other health markers.
Rochester, MinnesotaAges 40–55 - NCT07632001Recruiting
Miro3D Wound Matrix for Diabetic Foot Ulcers
This trial tests a new wound-healing product called Miro3D to help diabetic foot ulcers heal better. You would receive this product along with standard wound care to see if it helps your ulcer close faster than standard treatment alone.
Phoenix, ArizonaAges 18 years+ - NCT07762144Enrolling by invitation
Recovery after cardiac arrest
This trial collects health information from people who have survived a cardiac arrest (when the heart stops) and have been brought back to life. The information may help doctors improve care and recovery after this event.
Beijing, Beijing MunicipalityAges Any age - NCT03238690Recruiting
LVAD conditioning to help your heart recover
This study looks at an approach called “conditioning” using your LVAD (a heart pump) while you wait for a transplant. It aims to see whether your heart muscle may recover better during planned changes in support.
Salt Lake City, UtahAges 18 years+ - NCT07163299Enrolling by invitationPhase 1/Phase 2
Cooling artery treatment with magnesium for stroke clot removal
This trial tests adding a cooled magnesium solution directly into the brain artery during standard clot removal to see if it helps limit brain damage and improve recovery. The magnesium and cooling aim to protect brain tissue while the clot is being taken out.
Xuzhou, JiangsuAges 18–80 - NCT07136012RecruitingPhase 3
Olpasiran trial to lower Lp(a) and prevent first heart attack or stroke
This trial tests if olpasiran can lower a type of cholesterol called Lp(a) to help prevent a first major heart attack, stroke, or other heart problems. It is for people at higher risk due to risk factors or early signs of artery disease, but who have not yet had a heart attack or stroke.
Alexander City, AlabamaAges 50–105 - NCT07234032RecruitingPhase 3
Long-term follow-up study of TPIP for PH-ILD
This trial is a long-term follow-up study for people who already completed a previous study of an inhaled treprostinil medication (TPIP) for pulmonary hypertension caused by interstitial lung disease (PH-ILD). It tests whether continued treatment with TPIP is safe and effective over a longer period.
Naples, FloridaAges 18 years+ - NCT06980116RecruitingPhase 1
Finding the right dose of EXS73565 for relapsed B-cell cancers
This study tests a new oral medication (EXS73565) for people with B-cell blood cancers that came back or didn't respond to standard treatments. It aims to find the best dose and check if it's safe and helpful.
TbilisiAges 18 years+ - NCT07422688Enrolling by invitation
Using light scans to find heart artery blockages
This trial uses a special light-based scan (optical coherence tomography, or OCT) to help doctors see inside your heart arteries and find the exact blockage causing your heart attack. It may help guide treatment more precisely.
GenkAges 18 years+ - NCT07348640RecruitingPhase 3
Study of new MRI dye for blocked blood vessels
This trial tests a new MRI contrast dye (gadopiclenol) to see if it works as well as the standard dye for finding blocked or narrowed blood vessels. If you have symptoms of vascular disease, you may be able to join and help compare the two dyes.
Los Angeles, CaliforniaAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,976 recruiting cardiology studies from the U.S. registry right now, out of 15,179 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.