Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,976 recruiting studies in this area right now.
By phase
- Not applicable7,959
- Phase 2483
- Phase 4479
- Phase 3447
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 386
Top conditions
- Stroke841
- Heart Failure567
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma334
- Atrial Fibrillation268
- Ischemic Stroke201
- Atrial Fibrillation (AF)140
- Acute Ischemic Stroke137
- Myocardial Infarction102
- Pulmonary Hypertension100
- Congenital Heart Disease85
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California460
- Alabama197
- Massachusetts183
- Arizona174
- New York161
- Florida145
- Maryland120
- Illinois119
- Minnesota119
- Texas118
Recruiting studies9,973 total
- NCT06588634Recruiting
A study of a catheter device for high-risk pulmonary embolism
This trial tests a new treatment for people with a severe, high-risk pulmonary embolism (blood clot in the lung). It uses a catheter device to remove the clot and help the heart work better.
New Haven, ConnecticutAges 18 years+ - NCT07559006Recruiting
Shoulder Pain After Stroke and Its Effects on Arm Function
This study looks at how shoulder pain affects arm movement, balance, and daily activities in people who've had a stroke. Researchers want to understand the connection between shoulder pain and physical recovery after stroke.
Kütahya, KütahyaAges 18–80 - NCT07489352Enrolling by invitation
Beta-blocker dose adjustment for older heart failure patients
This study helps older adults with heart failure gradually increase their beta-blocker dose to a level that guidelines recommend, using an approach tailored to each person.
New York, New YorkAges 60 years+ - NCT07118358Recruiting
Testing a new leadless pacemaker for slow heart rhythms
This trial studies a small, leadless pacemaker that is placed directly in the heart to treat slow heart rhythms. It's designed for people who need a pacemaker for the bottom chambers of the heart.
Burlingame, CaliforniaAges 18 years+ - NCT06393920Recruiting
PulseSelect PFA heart ablation registry study
This registry study collects information from people with atrial fibrillation (an irregular heartbeat) who are having a procedure using the PulseSelect PFA system. It helps doctors understand how well this treatment works in real-world settings.
HasseltAges 18 years+ - NCT01099982Recruiting
Studying heart tissue and blood changes after advanced heart care
This trial studies how blood and heart tissue change in people with advanced heart failure who are getting an LVAD (a heart pump) or a heart transplant. It may help doctors better understand what’s happening in the heart before and after these treatments.
Murray, UtahAges 13 years+ - NCT05211401RecruitingPhase 2
Testing rituximab for heart attack patients
This study tests whether adding the drug rituximab to standard heart attack treatment can reduce damage to the heart muscle after a heart attack. Rituximab is usually used for immune system conditions, and it may help calm inflammation and protect the heart. Participants must have a certain type of heart attack and be treated quickly.
ParisAges 18 years+ - NCT07420907Recruiting
Tracking heart health over time
This study uses a wearable patch to monitor heart-related signs in people with heart conditions. It aims to learn more about how these conditions progress, which could help improve future care.
Chicago, IllinoisAges 18 years+ - NCT07220798Recruiting
A program to support caregivers of people with heart failure and memory problems
This study tests a program to help caregivers of people with heart failure and memory problems take better care of themselves, so they can feel better and support their loved one more effectively.
New York, New YorkAges 18–101 - NCT07759427Recruiting
Using a new mapping method to guide treatment for fast heartbeats after a heart attack
This study tests a new way to find the exact spot in the heart that causes rapid heartbeats, so doctors can treat it more precisely with a procedure called catheter ablation.
BrightonAges 18 years+ - NCT07759635Recruiting
Effects of Plan B on heart health in young women
This study looks at how the emergency contraceptive Plan B (levonorgestrel) affects heart and blood vessel health in young, naturally cycling women. Participants will take the medication and have their cardiovascular health measured over a short period.
Hamilton, OntarioAges 18–35 - NCT07759791Recruiting
Life coaching after stroke to rejoin valued activities
This trial tests a coaching program that helps people who have had a stroke get back into activities they value, like hobbies or social outings. It may help you feel more connected and improve your quality of life.
Kingston, OntarioAges 18 years+ - NCT06542120Recruiting
Child health body sounds study
This study looks at how well a computer system can check children's health by listening to body sounds, like those from the heart, lungs, or belly. It is testing an AI system to see if it works well as an extra check alongside regular medical care.
Wuhan, HubeiAges Up to 18 years - NCT07760363Recruiting
Foot exercise device for leg swelling
This study tests if using a foot pedal device while lying down can help reduce leg swelling in the hospital. It aims to see if this simple exercise can improve comfort and outcomes for people with fluid buildup.
Tulsa, OklahomaAges 18 years+ - NCT07761910RecruitingPhase 2
Study of heart effects of radiation therapy using PET-CT for stage III lung cancer
This study looks at whether PET-CT scans can help detect heart damage caused by radiation therapy in patients with stage III lung cancer. If you're getting chemotherapy and radiation together, you may participate to help doctors find ways to reduce heart risks.
Indianapolis, IndianaAges 18 years+ - NCT06630104Recruiting
Studying blood cell changes after CAR-T therapy for blood cancers
This study looks at how CAR-T therapy affects blood cell counts (cytopenia) in people with multiple myeloma or certain lymphomas/leukemias. You will provide biological samples to help researchers understand these effects.
Scottsdale, ArizonaAges 18 years+ - NCT07453407Recruiting
Tavi valve vs surgery for severe aortic regurgitation
This trial compares a new catheter-based valve (J-Valve) with open-heart surgery for people with severe aortic regurgitation, a condition where the aortic valve doesn't close tightly. It aims to see which treatment is safer and more effective.
Hefei, AnhuiAges 65 years+ - NCT07102628RecruitingPhase 3
Early treatment with inclisiran for heart attack patients
This study tests if starting inclisiran soon after a heart attack helps lower cholesterol further in patients already on statins. The goal is to see if early treatment can reduce future heart risks.
Capital Federal, Buenos AiresAges 18 years+ - NCT06789913RecruitingPhase 2
Testing RLY-2608 for growth disorders linked to PIK3CA mutations
This trial tests a new medicine, RLY-2608, that targets the specific genetic change (PIK3CA mutation) causing overgrowth conditions. It aims to see if the drug can slow or stop the growth of affected tissues.
Phoenix, ArizonaAges 2 years+ - NCT06981247Recruiting
Heart disease prevention for office workers
This study tests ways to help city bank employees in Karachi lower their risk of heart disease and stroke. It focuses on people who sit a lot at work and want to prevent heart problems.
Karachi, SindhAges 20–65 - NCT06578104Recruiting
Pulsed AF Study: PulseSelect Catheter for Afib
This study tests a new way to treat atrial fibrillation (Afib) using a special catheter system called PulseSelect that delivers short bursts of energy to create scar tissue in the heart. It is for people whose Afib comes and goes or stays for a while but not more than a year, and who have not had a prior ablation procedure or have a pacemaker or defibrillator.
Tampa, FloridaAges 18 years+ - NCT07650032Recruiting
Freezing Treatment for Abnormal Heart Rhythms
This trial tests a freezing catheter procedure to treat dangerous, recurring abnormal heart rhythms (ventricular tachycardia) in patients whose hearts are weakened and whose current medications haven't worked. The procedure aims to scar the tissue causing the arrhythmia so your heart beats normally again.
Phoenix, ArizonaAges 18 years+ - NCT05639478Recruiting
Foot care and exercise program for people with diabetes
This trial tests whether a structured foot-care and exercise program in primary care helps adults with diabetes. It may help you stay more active and reduce foot problems by teaching daily care and safe movement.
Limeira, São PauloAges 18 years+ - NCT06604884Recruiting
Pipeline Vantage device study for brain aneurysms
This study follows people who receive the Pipeline Vantage device to treat a brain aneurysm. It helps doctors learn more about how well the device works in real-life use.
Jacksonville, FloridaAges 22 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,976 recruiting cardiology studies from the U.S. registry right now, out of 15,179 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Pain
- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.