Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,049 recruiting studies in this area right now.
By phase
- Not applicable8,023
- Phase 2486
- Phase 4480
- Phase 3451
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 387
Top conditions
- Stroke854
- Heart Failure568
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma330
- Atrial Fibrillation272
- Ischemic Stroke199
- Atrial Fibrillation (AF)145
- Acute Ischemic Stroke141
- Pulmonary Hypertension103
- Myocardial Infarction99
- Congenital Heart Disease86
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California468
- Alabama199
- Massachusetts182
- Arizona176
- New York165
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas119
Recruiting studies10,046 total
- NCT07002697Recruiting
Study of blood vessel shape and plaque buildup
This study looks at how the shape of your blood vessels affects the buildup of plaque (atherosclerosis) and blood flow. It may help doctors better understand heart disease risk.
DhakaAges 40–70 - NCT07003477Recruiting
Biomarker study for early stroke type diagnosis
This study uses blood tests to quickly identify the type of stroke in patients arriving at the emergency room. It aims to help doctors choose the best treatment early on.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07003568RecruitingPhase 1
CAR-T cell therapy for multiple myeloma with bone or organ spread
This trial tests a new CAR-T cell treatment that targets two proteins (BCMA and GPRC5D) on myeloma cells. It is for patients whose multiple myeloma has come back or stopped responding to treatment and has spread outside the bone marrow (extramedullary disease). The goal is to see if this dual-target approach can attack the cancer more effectively.
ShanghaiAges 18–75 - NCT07003555RecruitingPhase 1
Dual-target CAR-T therapy for multiple myeloma with extramedullary disease
This trial tests a new CAR-T cell treatment that targets two proteins (BCMA and CD19) on myeloma cells. It is for patients whose multiple myeloma has come back or stopped responding to other treatments and has spread to tissues outside the bone marrow.
ShanghaiAges 18–75 - NCT07003646Recruiting
Treating acute pulmonary embolism with clot-dissolving or catheter procedures
This study looks at how well different treatments work for a blood clot in the lung (pulmonary embolism). It includes people who are getting or have already gotten a clot-dissolving medicine or a catheter procedure to remove the clot.
AarhusAges 18 years+ - NCT07004140Recruiting
New MRI for stroke in the first 24 hours
This trial is testing a new type of MRI machine (field-cycling MRI) to see if it can give better images of the brain right after a stroke. It's for people with moderate to severe stroke symptoms who can have an MRI within 24 hours.
AberdeenAges 18 years+ - NCT07004673Recruiting
PET/MR imaging for carotid artery plaque risk
This trial uses special PET/MR scans to look at fatty buildup in your neck arteries to see which ones might be dangerous. It could help doctors better understand your stroke risk and choose the right treatment.
Shanghai, Shanghai MunicipalityAges Any age - NCT07005024RecruitingPhase 3
Blood thinner dosing study for people with cancer starting treatment
This trial tests different ways to take the blood thinner apixaban to prevent blood clots in people with cancer who are starting or switching their cancer treatment. It aims to find the best dose for safety and effectiveness.
Burlington, VermontAges 18 years+ - NCT07005141Recruiting
iHub Stent-Graft for Iliac Artery Aneurysms
This study tests a new stent-graft device for treating aneurysms in the iliac artery. It may be an option if you have an aneurysm that has grown or is large enough to need treatment.
Florianópolis, Santa CatarinaAges 18 years+ - NCT07006064Recruiting
Comparing oxygen methods during TAVI for older patients
This trial tests a new oxygen device (SuperNO2VA) against standard oxygen to prevent low oxygen levels in patients aged 65 and older who are getting a heart valve procedure (TAVI) while sedated. The goal is to see which method keeps oxygen levels safer.
AnkaraAges 65 years+ - NCT07006467Recruiting
Study of a dissolving scaffold for leg artery blockages
This trial tests a new type of absorbable scaffold (like a temporary mesh) that is placed inside a blocked artery below the knee to restore blood flow. It is for people with severe leg pain or small ulcers due to chronic limb-threatening ischemia (CLI) who have a short blockage in a specific artery.
GrazAges 18 years+ - NCT07006493Recruiting
Radiofrequency ablation for obstructive hypertrophic cardiomyopathy
This trial tests a new treatment that uses radiofrequency energy (similar to heat) to shrink the thickened heart muscle blocking blood flow. It is for people with obstructive hypertrophic cardiomyopathy who have symptoms despite medication and are not able or willing to have heart surgery.
Beijing, Beijing MunicipalityAges 18–80 - NCT07006649Recruiting
Study of blood flow in the eye for pseudoxanthoma elasticum
This study looks at blood flow in a layer of the eye called the choriocapillaris in people with pseudoxanthoma elasticum (PXE). It compares these findings with healthy volunteers to understand eye changes before they become severe.
AngersAges 18 years+ - NCT07007143RecruitingPhase 4
Blood thinner study after heart valve repair
This trial tests different blood-thinning medicines after a mitral valve repair procedure (TEER) in people who do not need long-term blood thinners. It aims to find the safest and most effective strategy to prevent blood clots.
Beijing, Beijing MunicipalityAges Any age - NCT07008391Recruiting
High-sensitivity troponin test in ambulance care
This trial tests whether using a high-sensitivity troponin I test in the ambulance, along with standard care, can help emergency medical services better identify heart attacks. This might lead to faster treatment for patients with chest pain or suspected heart attack.
Stockholm, ÅrstaAges 18 years+ - NCT07008365RecruitingPhase 3
Measuring belly pressure and ultrasound to guide fluid removal in heart failure
This trial tests whether using belly pressure and bedside ultrasound can help doctors better manage fluid removal (decongestion) in people hospitalized with heart failure. The goal is to see if this approach leads to better outcomes.
ZaragozaAges 18–100 - NCT07009132Recruiting
Liver function test for adults with Fontan or heart failure
This study tests a simple liver function test (called dual cholate clearance) to see how well it works in adults with a Fontan circulation or right heart failure. It aims to help doctors better detect liver problems in these heart conditions.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07009418Recruiting
CT scan vs. usual care after heart stent or balloon treatment
This trial tests whether a CT scan of the heart arteries is a safe and effective alternative to standard follow-up tests in people who have had a stent or drug-coated balloon placed in a high-risk coronary artery. It may help reduce the need for additional invasive procedures.
Bucheon-siAges 19 years+ - NCT07009652Recruiting
Optimizing mobile ECMO for sudden cardiac arrest patients
This trial tests a better way to get a mobile team that can start ECMO (a heart-lung machine) to people who have a sudden cardiac arrest outside the hospital. The goal is to see if this approach can help save more lives in certain regions.
Ostrava, Moravian-Silesian RegionAges 3–60 - NCT07009873Recruiting
Wearable ultrasound sensor trial for heart, leg, or ICU patients
This trial tests a wearable ultrasound sensor that can be stuck to the skin to monitor your heart, leg blood clots, or vital signs in the ICU. It may replace bulky machines and let doctors see your condition more easily and continuously.
Beijing, Beijing MunicipalityAges 18–70 - NCT07010029Recruiting
Heart vein device for angina with no blocked arteries
This trial tests a special device placed in a vein of the heart to help patients who have chest pain (angina) but no major blockages in their heart arteries. It is designed for people who have tried maximum medications but still have symptoms.
WarsawAges 18 years+ - NCT07010094Recruiting
Shockwave balloons for hardened heart artery blockages
This trial tests a special balloon that uses shock waves to crack calcium in heart arteries, making it easier to place a stent. It is for people with chest pain or signs of heart strain due to a single, severely blocked artery with dense calcium.
Fujian, XiamenAges 18–85 - NCT07010536Recruiting
Virtual reality music therapy for stroke recovery
This study tests whether combining virtual reality games with music therapy can help improve thinking and movement skills in people who had a stroke within the last 6 months. It may be a good option if you are between 50 and 75 and can sit up and use your hearing and vision.
Istanbul, IstanbulAges 50–75 - NCT07011459Recruiting
Cooking for health in older adults
This study looks at whether a healthy cooking program can help people prevent heart disease and cancer. It is for older adults who want to learn to cook in a way that may lower their risk for these conditions.
New Orleans, LouisianaAges 55–120
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,049 recruiting cardiology studies from the U.S. registry right now, out of 15,440 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.