Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT07617961Recruiting
THERAVEX Spray for Wound and Ulcer Healing
This trial tests a topical spray treatment designed to help heal various types of skin wounds, including burns, pressure sores, and diabetic ulcers. The spray may help your wound heal faster and more effectively.
BarcelonaAges 18 years+ - NCT07619820RecruitingPhase 1
CSL300 Safety Study for Kidney Dialysis Patients
This study tests how a new drug called CSL300 (clazakizumab) works in the body of people with end-stage kidney disease who are on dialysis. Researchers want to understand if it's safe and how your body processes it.
BeijingAges 18 years+ - NCT07619885RecruitingPhase 1
Testing a New Blood Thinner Called CG-0255 in Healthy People
This study tests how a new blood-thinning medication (CG-0255) works in the body and compares it with Plavix, a common blood thinner. Researchers will measure how much of the drug enters your bloodstream and what effects it has on your blood clotting ability.
Miami, FloridaAges 18–55 - NCT07619872Recruiting
Safety study of KONECT RESILIA heart valve replacement
This study tracks how well a new artificial aortic valve and aorta graft (called KONECT RESILIA) work after surgery in real-world patients. Researchers want to understand if it's safe and performs well over time in people who need this valve replaced.
München, BavariaAges 18 years+ - NCT07614152RecruitingPhase 3
Growth hormone treatment for girls with Turner syndrome
This study tests whether a new long-acting growth hormone injection helps girls with Turner syndrome grow taller. Turner syndrome is a genetic condition that affects growth, and this trial will see if this treatment is safe and effective.
AnyangAges 2–12 - NCT07613294RecruitingPhase 3
Testing lepodisiran to reduce heart plaque buildup
This study tests whether a new medicine called lepodisiran can shrink plaque in heart arteries for adults with high Lp(a) (a type of cholesterol linked to heart disease) who have had a heart event or are at serious risk. The trial uses CT scans to monitor changes in your arteries.
La Jolla, CaliforniaAges 45–80 - NCT06706635Recruiting
Better info for aortic stenosis patients before TAVI
This trial tests whether giving extra information before heart valve replacement (TAVI) helps patients feel more informed and improves their reported outcomes. If you have severe aortic stenosis and are planning to get a TAVI, this study may be for you.
Bad OeynhausenAges 18 years+ - NCT04444349Recruiting
CoQ10 to reduce inflammation after heart surgery
This study tests whether CoQ10 (a natural nutrient) can lessen harmful inflammation and help protect organs after cardiovascular surgery. If you qualify, you may receive CoQ10 during the surgical period and be followed for how your body responds.
Beijing, Beijing MunicipalityAges 18–90 - NCT05959746Recruiting
AI video tool study for early stroke and TIA diagnosis
This study collects short video and clinical information from people being checked for stroke or a “mini-stroke” (TIA) soon after symptoms start, to help build an AI diagnostic tool. You may be contacted again for a follow-up visit within about 4 months.
Nîmes, GardAges 18 years+ - NCT06132399Recruiting
Virtual reality software for recent stroke recovery
This trial tests whether using virtual reality exercises can help people who recently had a stroke regain movement in their arms or legs. If you had a stroke 7 to 14 days ago and have weakness on one side, this study may help with your recovery.
Almería, AlmeríaAges 18 years+ - NCT06424834RecruitingPhase 2/Phase 3
Targeted medicines for chest pain without blocked arteries
This study tests if specific heart medicines (like beta-blockers or calcium channel blockers) can help people with chest pain that is not caused by blocked arteries. It aims to treat the tiny blood vessels or spasms that may be the real cause of your pain.
Palo Alto, CaliforniaAges 18 years+ - NCT06587308Recruiting
How pressure garments affect arm function after stroke
This study tests whether wearing special pressure garments on the arm can improve movement, feeling, and quality of life for people who have had a stroke. It may help if you have some arm weakness but not too much tightness or other health problems.
Weifang, ShandongAges 18–80 - NCT06707454Recruiting
Recovery after open heart surgery in older adults
This study looks at how older adults recover after open heart surgery, focusing on brain and nerve health. It may help researchers understand the effects of surgery on thinking and memory.
CairoAges 60 years+ - NCT06707532Recruiting
Muscle relaxants for safer heart rhythm treatment
This study tests if giving muscle relaxants before a heart ablation procedure can protect muscles from damage. Ablation uses energy to fix irregular heartbeats, and muscle relaxants might make it safer.
Wroclaw, Lower Silesian VoivodeshipAges 18–90 - NCT06197347Recruiting
Web program to help older adults be more active after heart treatment
This study tests a nurse-led website designed to help older adults become more physically active after heart surgery or a stent procedure. If you are interested in getting more active and live in the Montreal area, this program may support your recovery.
Montreal, QuebecAges 65 years+ - NCT05997680Recruiting
Yoga for attention in kids with heart disease
This study tests if a parent-child yoga program can help improve attention in children aged 4 to 6 with congenital heart disease who have attention difficulties. You and your child would attend yoga sessions together for 8 weeks.
Montreal, QuebecAges 4–6 - NCT06245629Recruiting
Comparing two drug combos for relapsed multiple myeloma
This trial looks at two different drug combinations given before a second stem cell transplant for multiple myeloma that has come back after first treatment. It aims to see if adding two extra drugs (bortezomib and bendamustine) to the standard drug (melphalan) works better than using the standard drug alone.
UppsalaAges 18 years+ - NCT06709950Recruiting
Art therapy for movement recovery after stroke
This study tests art therapy (like painting or clay) to help improve movement and emotional well-being after a recent stroke. It is designed for people in the subacute phase (2 weeks to 3 months after their first stroke) who have mild to moderate physical challenges and can actively participate in creative activities.
Jiamusi, HeilongjiangAges 40–75 - NCT06709690Recruiting
AI-powered PET/MR scanner for children with suspected cancer
This study tests a new, fast, and quiet AI-powered PET/MR scanner to take detailed pictures of children with suspected cancer. It aims to make the imaging experience easier and more comfortable for kids.
Shanghai, Shanghai MunicipalityAges Up to 18 years - NCT07609095Recruiting
Testing pulse checks to assess blood circulation during emergency care
This study examines whether checking a patient's pulse at the wrist or other sites can help doctors quickly assess blood circulation problems during emergencies. The goal is to see if simple pulse checks match what more complex monitoring devices show, helping guide faster treatment decisions.
Stockholm, Stockholm CountyAges 18 years+ - NCT07608822Recruiting
Dual-chamber pacemaker with specialized heart block pacing
This study follows patients who recently received a dual-chamber pacemaker (a device that helps regulate heartbeat) designed to work differently when the heart's electrical signals are delayed or blocked. The trial checks whether this new pacing approach safely reduces irregular heart rhythms and works well over time.
Ústí nad LabemAges 18–18 - NCT07609940RecruitingPhase 4
Linvoseltamab plus tocilizumab for heavily treated multiple myeloma
This trial tests a combination of two drugs (linvoseltamab and tocilizumab) for adults with multiple myeloma that has stopped responding to standard treatments. Tocilizumab is added to help reduce serious side effects from the main drug.
Los Angeles, CaliforniaAges 18 years+ - NCT07606274RecruitingPhase 1/Phase 2
Study of NVC-001 for heart muscle disease caused by LMNA gene change
This trial tests an experimental drug called NVC-001 for people with a specific genetic heart condition (LMNA-related dilated cardiomyopathy) that causes the heart to become weak and enlarged. The goal is to see if the drug can help improve heart function.
Birmingham, AlabamaAges 18 years+ - NCT07609862RecruitingPhase 1/Phase 2
Rocbrutinib and Lacutoclax for B-Cell Blood Cancers
This trial tests a combination of two new drugs (rocbrutinib and lacutoclax) to treat B-cell lymphomas and leukemias. The goal is to see if this combination works better than standard treatments, especially for patients whose cancer has come back or stopped responding to previous therapy.
TianjinAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
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- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.