Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,982 recruiting studies in this area right now.
By phase
- Not applicable7,962
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke844
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California465
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas118
Recruiting studies9,979 total
- NCT06615479RecruitingPhase 3
New treatment vs standard care for relapsed multiple myeloma
This trial tests a new treatment called BMS-986393 (a type of CAR T-cell therapy) compared to standard treatments for adults with multiple myeloma that has come back or is not responding to therapy, and who have already been treated with lenalidomide (Revlimid). The goal is to see if the new treatment works better.
Birmingham, AlabamaAges 18 years+ - NCT07483255Recruiting
Fetal embolization trial for vein of Galen malformation
This trial tests a fetal procedure to treat a rare brain blood vessel condition called vein of Galen malformation. The goal is to improve the baby's outcome by closing off abnormal connections inside the brain before birth.
Boston, MassachusettsAges 18 years+ - NCT06404268RecruitingPhase 1/Phase 2
Helping stroke survivors regain ankle movement with exercise
This study tests whether gentle leg exercises can help people recovering from a recent stroke. The focus is on improving ankle movement and strength on the weak side.
Baltimore, MarylandAges 30–85 - NCT07722793Enrolling by invitation
EVAR study: heart and artery changes after aneurysm repair
This study looks at how the heart and large arteries change after endovascular repair of an abdominal aortic aneurysm (a bulge in the main artery in your belly). It may help doctors understand if the repair improves heart function and vessel stiffness over time.
OsijekAges 18 years+ - NCT06024746RecruitingPhase 3
Finerenone plus SGLT2i for hospitalized heart failure
This trial tests whether adding two heart medicines together (finerenone and an SGLT2 inhibitor) helps people who are in the hospital for heart failure recover better. It may be an option for you if you are currently hospitalized and your heart stress markers are high.
Fairhope, AlabamaAges 18 years+ - NCT06440694RecruitingPhase 3
Colchicine to reduce inflammation after a first blood clot in the leg
This trial tests if colchicine, a medicine used for gout, can reduce inflammation after a first deep vein thrombosis (blood clot in a large leg vein). It might help prevent long-term leg problems from the clot.
Ottawa, OntarioAges 18 years+ - NCT07348341Recruiting
Laser treatment for blocked heart arteries registry
This study collects information from patients with blocked heart arteries who receive a special laser treatment (ELCA) to open the blockage. It will help doctors understand how well this laser works in different situations.
MadridAges 18 years+ - NCT07275151Recruiting
Testing a new heart procedure for atrial fibrillation
This trial tests a new method called pulsed field ablation (PFA) to treat irregular heartbeats (atrial fibrillation) by isolating the veins that carry blood to your heart. It aims to see how well this procedure works and if it's safe for you.
Ypsilanti, MichiganAges 21 years+ - NCT06371417RecruitingPhase 1
Testing RAY121 for several immune diseases (RAINBOW trial)
This trial tests a new medicine called RAY121 (an antibody) for people with certain autoimmune diseases. It aims to see if RAY121 is safe and how the body handles it. If you have one of these conditions and meet the basic health requirements, you might be able to join.
Orange, CaliforniaAges 18–85 - NCT07719517Recruiting
Morning activities to boost mood after stroke
This study tests if doing simple, guided activities in the morning can help improve your mood after a stroke. If you often feel down and have trouble getting going in the morning, this program might offer a way to feel better.
Hong KongAges 18 years+ - NCT02328573Recruiting
Group singing for people after stroke and their caregivers
This study looks at whether group singing can help people who have had a stroke and support the people who care for them. If you or your caregiver are interested in group singing, this may be a simple way to try the intervention while contributing to research.
New York, New YorkAges 18 years+ - NCT07171060Recruiting
A study of a new device for leaky heart valve
This trial tests a new device called Laplace TTVR to replace a leaky tricuspid valve in the heart without open surgery. It is for people with severe symptoms despite medical treatment.
Ottawa, OntarioAges 60–90 - NCT07718997RecruitingPhase 1
Social skills training for people with sex chromosome differences
This trial tests a social management training program for adults with sex chromosome aneuploidies (SCA). The goal is to see if it can help improve social skills and daily life. It is a small feasibility study to prepare for larger future trials.
OsloAges 16–65 - NCT07429721RecruitingEarly Phase 1
Testing QI-019A for multiple myeloma that came back
This trial tests a new drug called QI-019A for people whose multiple myeloma has returned or stopped responding to at least two prior treatments. The goal is to see if it is safe and if it can help control the disease.
Wuhan, HubeiAges 18 years+ - NCT06429930RecruitingPhase 1
Safety study of L608 in healthy adults
This trial tests an investigational medicine called L608 in healthy volunteers to check its safety and how the body processes it. It may help researchers understand the right dose for future studies.
ChristchurchAges 18–65 - NCT07721025RecruitingPhase 2
Gene therapy trial for Friedreich ataxia heart disease
This trial tests a one-time gene therapy called LX2006 for heart problems caused by Friedreich ataxia. The goal is to see if it can improve heart function and structure.
Tampa, FloridaAges 6 years+ - NCT07719894RecruitingPhase 4
Preventing heart problems in type 2 diabetes with cilostazol and aspirin
This trial tests whether taking cilostazol and aspirin together can help prevent heart attacks, strokes, and other cardiovascular events in people with type 2 diabetes who have early signs of artery disease or metabolic syndrome. It aims to see if this combination is more effective than aspirin alone.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT07236502Recruiting
Moving forward with myeloma: Exercise and lifestyle program
This study tests a lifestyle program with exercise and nutrition guidance for people who have had multiple myeloma for at least one year. The goal is to see if it helps improve daily wellbeing and strength.
Maywood, IllinoisAges 18 years+ - NCT06214507Recruiting
Danon disease natural history study
This study follows people with Danon disease over time to better understand how the condition progresses. It may help guide future treatments.
Phoenix, ArizonaAges 8 years+ - NCT00552357Recruiting
Finding risk factors for poor lung transplant function
This study looks at what increases the chance of developing a serious complication called “primary graft dysfunction” shortly after a lung (or heart-lung) transplant. The results may help doctors better predict risk and improve care after transplant.
Philadelphia, PennsylvaniaAges 13–68 - NCT05086978Enrolling by invitation
Retina camera test in people with heart failure
This study uses a simple camera to take pictures of the back of your eye (retina) to see how useful retinal imaging might be in people with heart failure. You may also be invited as a healthy control, depending on the group you belong to.
Cleveland, OhioAges 18 years+ - NCT06188689Recruiting
Testing a new diagnostic test for heart rhythm disorders
This study is evaluating a new diagnostic test for Calcium Release Deficiency Syndrome (CRDS) and related heart rhythm disorders. It aims to find out if this test can accurately identify patients with these conditions, which could lead to better diagnosis and treatment.
San Francisco, CaliforniaAges Any age - NCT07719387Enrolling by invitation
Vagus nerve stimulation to boost thinking and learning after stroke
This study tests if vagus nerve stimulation, delivered through an implanted device, can help improve thinking and learning in people who have had a stroke. You would use the device at home for six weeks.
Stony Brook, New YorkAges 22 years+ - NCT07644364RecruitingPhase 1
Blood Pressure Medication Study for Japanese Adults
This early-stage trial tests a new blood pressure medication called HJB647 in Japanese adults with elevated or high blood pressure. The study aims to see if the drug is safe and how the body handles it.
Sumida Ku, TokyoAges 18–60
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,982 recruiting cardiology studies from the U.S. registry right now, out of 15,268 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
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- Pain
- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.