Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,982 recruiting studies in this area right now.
By phase
- Not applicable7,962
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke844
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California465
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas118
Recruiting studies9,979 total
- NCT07619872Recruiting
Safety study of KONECT RESILIA heart valve replacement
This study tracks how well a new artificial aortic valve and aorta graft (called KONECT RESILIA) work after surgery in real-world patients. Researchers want to understand if it's safe and performs well over time in people who need this valve replaced.
München, BavariaAges 18 years+ - NCT07707076Recruiting
Flow diverter vs standard treatment for wide-neck brain aneurysms
This trial compares a flow diverter device to standard endovascular treatment for unruptured wide-neck brain aneurysms at a bifurcation. If you have this type of aneurysm, this study may help determine which treatment works better.
Guangzhou, GuangdongAges 18–75 - NCT06806761Recruiting
Tracking balance and walking after stroke
This study tracks how walking and balance improve in the first weeks after a stroke. It uses simple tests to measure your recovery over time, with no experimental treatments.
Sint-Pieters-Leeuw, Brussels CapitalAges 18 years+ - NCT06397729Recruiting
Testing a new tool to support healthy habits in rural clinics
This study is testing a new way to help people improve their heart health by making healthy changes in their daily habits. It focuses on patients in rural primary care clinics who are at higher risk because of their weight.
St Louis, MissouriAges 18–64 - NCT06121843RecruitingPhase 1
Study of CAR-T cell therapy in combinations for multiple myeloma
This trial tests a new CAR-T cell therapy (called arlocabtagene autoleucel) combined with other drugs for multiple myeloma that has returned or stopped responding. It aims to find a safe and effective dose while tracking how well the treatment works.
Birmingham, AlabamaAges 18 years+ - NCT07707037Recruiting
Helping parents cope after a child's cardiac arrest
This study tests if providing clearer information to parents after their child's cardiac arrest can reduce fear and anxiety. It is for parents of children under 17.5 years old who are expected to leave the hospital soon.
Philadelphia, PennsylvaniaAges birth–17 years - NCT06244953Recruiting
Heart failure support program with palliative care
This study tests whether a tailored program that includes palliative care (extra support for comfort and quality of life) can help people with advanced heart failure and their family caregivers. It aims to reduce hospital visits and improve well-being.
SingaporeAges 21–99 - NCT07299994Recruiting
Intravenous thrombolysis for specific brain strokes
This trial tests whether a clot-busting drug given through a vein can help people with certain types of deep brain strokes that happen in small arteries. It looks at patients who can be treated within 24 hours of symptoms starting.
Vienna, State of ViennaAges 18 years+ - NCT07231757Recruiting
Blood pressure study for older adults
This study tests a treatment to lower blood pressure in adults aged 65 and older whose blood pressure is not well controlled with their current medications. It may be an option for those looking for additional ways to manage their hypertension.
Detroit, MichiganAges 65 years+ - NCT07293923Recruiting
Magenta Elevate™ study for cardiogenic shock
This trial tests a new heart pump called the Magenta Elevate™ to help people whose heart suddenly stops pumping enough blood (cardiogenic shock). It aims to improve blood flow and reduce strain on the heart.
TbilisiAges 40–89 - NCT06929897Enrolling by invitation
Comparing Two Ablation Methods for Persistent Atrial Fibrillation
This study compares two types of ablation (a procedure that uses energy to fix irregular heartbeats) for people with persistent atrial fibrillation. It tests whether adding extra treatment to the back of the heart's left upper chamber helps improve outcomes compared to standard treatment alone.
SeoulAges 20–80 - NCT07420465Recruiting
Heart and metabolic risks in pregnancy and after birth
This study looks at heart and metabolic health during late pregnancy and after delivery, tracking both healthy women and those with complications like high blood pressure or diabetes in pregnancy. The goal is to understand how these risks change and what can be done to improve long-term health.
AccraAges 18–45 - NCT07567625Recruiting
Heart Attack Treatment Without a Stent
This trial tests whether patients who have had a heart attack with a specific type of artery blockage can be safely treated without placing a metal stent (tube) in their artery. Doctors will monitor whether the blockage stays open on its own.
Harbin, HeilongjiangAges 18–75 - NCT05511389Recruiting
Testing better electrode placement for heart rhythm shock
This study tests whether two different positions of the electrodes (pads) used for an electrical shock work equally well for people with atrial fibrillation or flutter. It may help improve how safely and effectively the shock restores a normal rhythm.
Hamilton, OntarioAges 18 years+ - NCT05946629Recruiting
Drug-coated stent trial for narrowed heart arteries
This trial studies a drug-coated balloon (plus standard heart medicines) to treat a specific type of blockage in the heart arteries in people who need an intervention. It may help keep the artery open and prevent the narrowing from coming back, depending on how well you match the detailed heart and medication requirements.
Jonesboro, ArkansasAges 18 years+ - NCT07363161Recruiting
Drug-coated balloon vs. stent for high-risk heart disease
This trial compares two treatments for people with complex coronary artery disease who have high-risk conditions or complicated blockages: a drug-coated balloon (DCB) versus a drug-eluting stent (DES). Both are ways to open up narrowed arteries and keep them open without surgery.
HomburgAges 18 years+ - NCT06471036Recruiting
Improving cholesterol testing and treatment after a heart attack
This study tests whether giving extra education to doctors and patients can help improve cholesterol management after a heart-related hospitalization. It aims to see if a simple program can make sure patients get the right testing and treatment for high cholesterol.
Minneapolis, MinnesotaAges 18 years+ - NCT06933875Recruiting
Palliative care support for heart failure patients
This study tests a program to bring palliative care (extra support for comfort and quality of life) to people hospitalized with heart failure. Your doctor will take part, and if you qualify, you may get this additional care during your stay.
New Haven, ConnecticutAges 18 years+ - NCT05907629Recruiting
MRI study comparing blood thinners after a certain stroke
This trial looks at MRI scans to compare two types of blood-thinning medicines (one that affects blood-clotting and one that affects platelets) after a recent stroke caused by severe narrowing in certain brain arteries. It may help doctors understand which treatment works best while checking how the blood vessels and brain tissue look on MRI.
Birmingham, AlabamaAges 18 years+ - NCT07299981Recruiting
Brain water changes after clot-busting drug for stroke
This study looks at how much water builds up in brain tissue after a stroke is treated with a clot-busting drug. It may help doctors understand who will recover better.
ViennaAges 18 years+ - NCT05634031Recruiting
Study of heart vessel dysfunction seen on heart imaging
This study looks at coronary microvascular dysfunction (small blood vessel problems in the heart) using heart imaging. It may help researchers understand causes of chest tightness with activity and shortness of breath when the main heart arteries are not blocked.
New York, New YorkAges 18 years+ - NCT03344276Recruiting
Testing thinking and memory after carotid artery treatment
This study checks how a carotid artery procedure affects thinking and memory. You may be able to join if you’re an adult with significant carotid artery narrowing seen on ultrasound, and you can safely do follow-up MRI scans.
San Diego, CaliforniaAges 18 years+ - NCT03837574Recruiting
Registry for people with Tetralogy of Fallot and a defibrillator
This is a national registry that collects information about people with Tetralogy of Fallot who have an implantable defibrillator. It helps researchers better understand outcomes and care needs in this specific group.
ParisAges 18 years+ - NCT05951777RecruitingPhase 2
Stem cells from your own fat for chronic brain injury
This trial tests whether stem cells taken from your own fat and given through an IV can help people with long-term brain damage from a head injury. It is for adults who have not gotten better with standard treatments.
Houston, TexasAges 18–55
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,982 recruiting cardiology studies from the U.S. registry right now, out of 15,268 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.