Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT06083207RecruitingPhase 1/Phase 2
IBI3003 for multiple myeloma that has returned or not responded
This trial tests an investigational drug called IBI3003 in people with multiple myeloma that has come back or hasn't responded to previous treatments. The goal is to see if it is safe and effective.
Wollongong, New South WalesAges 18 years+ - NCT06005233Recruiting
Smartwatch heart monitoring after unexplained stroke
This trial uses a smartwatch to look for hidden atrial fibrillation (an irregular heart rhythm) in people who have had a stroke or TIA with no known cause. It could help find the reason for the stroke and guide treatment to prevent another one.
MunichAges 40 years+ - NCT06100718Recruiting
Detecting new cancer after a stroke in at-risk patients
This study looks for hidden cancers in people who have had a stroke and have high levels of a blood marker called D-dimer. It aims to see if a full cancer screening one year later can find new cancers that might have been missed.
Lausanne, Canton of VaudAges 18 years+ - NCT06258109Recruiting
Pregnancy and stroke risk after artery dissection
This study looks at women who had a cervical artery dissection (a tear in a neck artery) and later became pregnant. It wants to see if pregnancy raises the risk of another dissection or stroke.
Salt Lake City, UtahAges 18 years+ - NCT06141811Recruiting
Long-term safety study for diabetic foot ulcer treatment
This study follows up on patients who received an experimental cell sheet (ALLO-ASC-DFU) or a placebo in a previous trial. It checks for any new safety concerns over time.
Bucheon-si, Gyeonggi-doAges 19–75 - NCT06722222Recruiting
New surgery for carotid artery narrowing
This trial tests a specific surgical technique called Gao's Triple Eversion Carotid Endarterectomy for people with significant narrowing of the carotid artery. The goal is to prevent strokes by removing the blockage.
Hangzhou, ZhejiangAges Any age - NCT07560956Enrolling by invitation
Quality of Life in Adults With Untreated Fabry Disease
This study looks at how Fabry disease affects daily life in adults who haven't started treatment yet. Researchers want to understand your experiences and challenges to improve care for people with this rare genetic condition.
GothenburgAges 18 years+ - NCT07563257Recruiting
Comparing Two Mapping Catheters for Heart Rhythm Ablation
This trial compares two types of specialized catheters used during heart rhythm ablation procedures to help doctors confirm they've created the right burn patterns. If you're having ablation for persistent atrial fibrillation or flutter with complex burn lines planned, this trial may help improve how your procedure is done.
Be’er Ya‘aqovAges 18 years+ - NCT06653855Recruiting
Cupping for leg stiffness and movement after stroke
This study tests if cupping therapy can reduce leg stiffness and improve movement in people recovering from a stroke. You must be getting rehab at a specific clinic in Joliet.
Joliet, IllinoisAges 30–80 - NCT06717685RecruitingPhase 3
Adenosine vs Verapamil for rapid heart rate
This trial compares two medicines, adenosine and verapamil, to see which works better for stopping a sudden fast heart rhythm called SVT. If you have an episode of SVT that is stable enough to not need emergency shock treatment, you may be able to join.
Lahore, Punjab ProvinceAges 18–70 - NCT07565506RecruitingPhase 2
Nu-3 Gel for Mild Diabetic Foot Infections
This study tests a new gel treatment (Nu-3) for mild infections in diabetic foot ulcers. The goal is to find the right dose and see if it helps heal these wounds safely.
Los Angeles, CaliforniaAges 18 years+ - NCT07559799Recruiting
Melflufen and Dexamethasone for Relapsed Multiple Myeloma
This study tracks how melflufen (a cancer-fighting drug) combined with dexamethasone works in patients with multiple myeloma that has returned or stopped responding to previous treatments. Researchers will monitor your health and quality of life over time to understand the treatment's real-world effectiveness.
Freiburg im BreisgauAges 18 years+ - NCT07564375Recruiting
Testing a new graft for thoracic aorta problems
This early feasibility study tests a new branched stent graft (MBA device) designed to treat problems in the upper part of the aorta (the main artery from your heart) that involve branches going to your arms and head. The device may help patients who are considered too risky for traditional surgery.
Los Angeles, CaliforniaAges 18 years+ - NCT07567001RecruitingPhase 3
Testing NNC0487-0111 for Heart Failure and Obesity
This study tests whether a new medication called NNC0487-0111 can help people with heart failure who also have obesity. Researchers will compare it to a placebo (inactive pill) to see if it improves heart function and overall health.
Alexander City, AlabamaAges 18 years+ - NCT07560085Recruiting
Heart Pump Device to Help After Heart Surgery Complications
This trial tests a new heart-assist device designed to help patients whose hearts are too weak to pump blood on their own after heart surgery. The device is placed through a catheter (thin tube) and aims to improve blood flow and survival in people who don't respond to standard medications.
Fuzhou, FujianAges 18–80 - NCT07563777Recruiting
Long-term study of human aging and health
This is a long-term research study that follows people over time to understand how humans age. Researchers will collect information about your health and lifestyle to learn what helps people stay healthier as they get older.
Boulder, ColoradoAges 18 years+ - NCT05017142Recruiting
Pediatric brain inflammation registry for Swiss patients
This study is a registry that collects health information from children and teens in Switzerland diagnosed with certain inflammatory brain and spinal cord conditions. It helps researchers understand these illnesses better over time and may guide future treatments.
Aarau, Canton of AargauAges Up to 36 years - NCT06733714Recruiting
Brain stimulation plus memory training for older adults
This study tests whether a gentle, non-invasive electrical current applied to the scalp (tACS) combined with computer-based brain exercises can improve memory and thinking in older adults who have concerns about their cognitive health.
Rio de Janeiro, Rio de JaneiroAges 50 years+ - NCT06732232RecruitingEarly Phase 1
CAR-T therapy for multiple myeloma that returned or didn't respond
This early trial tests a new CAR-T cell treatment targeting three proteins (CD19, CD22, and BCMA) on myeloma cells. It's for people whose myeloma came back or didn't respond to at least three prior treatments.
ShanghaiAges 18–75 - NCT06322056Recruiting
Lower blood pressure and cholesterol targets for advanced kidney disease
This trial tests whether keeping blood pressure and cholesterol at lower-than-usual levels can help slow the decline of kidney function in people with advanced chronic kidney disease. If you have moderately to severely reduced kidney function and meet certain blood pressure and cholesterol criteria, you may be able to join.
SeoulAges 19 years+ - NCT06153888Recruiting
Heart strain during dialysis: a study on fluid removal
This study looks at how quickly fluid is removed during dialysis affects the heart. It may help find safer ways to manage fluid removal for people on hemodialysis.
UmeåAges 18 years+ - NCT06044922Recruiting
Using heart rate to predict brain injury after cardiac arrest
This study looks at how your heart rate changes (heart rate variability) to predict brain injury after a cardiac arrest. It may help doctors identify brain damage earlier so they can provide better care.
Brest, Brittany RegionAges 18 years+ - NCT06249945RecruitingPhase 4
Empagliflozin for heart failure with preserved ejection fraction and dialysis
This trial tests whether a medicine called empagliflozin (used for diabetes and heart failure) can help people with both heart failure (with preserved pumping ability) and end-stage kidney disease who are on dialysis. The study looks at how the drug affects heart function and overall well-being.
HsinchuAges 20 years+ - NCT07559942Recruiting
Apiban to Help Dialysis Fistulas Mature Successfully
This trial tests whether a blood-thinner medication called apixaban (Apiban) helps arteriovenous fistulas—surgically created connections in the arm for dialysis—develop and work better. If it helps fistulas mature faster and more reliably, it could reduce complications and improve treatment for kidney failure patients.
Lahore, Punjab ProvinceAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.