Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT07566624Recruiting
Registry study of Hydra heart valve replacement procedure
This study tracks patients who receive a Hydra artificial heart valve to replace a severely narrowed aortic valve. Researchers will follow your progress to understand how well the device works and its safety in real-world use.
Fuencarral-El PardoAges 18 years+ - NCT07564531Recruiting
Safe sedation for heart catheterization in children
This study tests whether a combination of two sedative medications (dexmedetomidine and ketamine) works safely and effectively to keep children calm and still during heart catheterization—a procedure where a thin tube is guided through blood vessels to the heart for diagnosis or treatment.
HanoiAges Up to 18 years - NCT07563660Recruiting
Heart imaging study for arrhythmogenic right ventricular cardiomyopathy
This study uses a special type of heart scan (FAPI PET/CT) to better visualize and understand arrhythmogenic right ventricular cardiomyopathy (ARVC), a condition where the heart muscle weakens and causes irregular heartbeats. The scan may help doctors understand the disease better and improve patient care.
Istanbul, FatihAges 18 years+ - NCT07559903Recruiting
Drug-coated balloon heart artery treatment registry
This study tracks outcomes in adults who receive a special balloon catheter (coated with medication) to open blocked heart arteries. Researchers collect data to understand how well this treatment works and any side effects that occur.
Phoenix, ArizonaAges 18 years+ - NCT07560280Recruiting
Tinnitus from Jugular Vein Narrowing: Diagnosis and Surgery Study
This study evaluates whether neck vein narrowing causes a specific type of tinnitus (ringing in the ears) and tests surgical treatment. If you have persistent tinnitus and imaging shows a narrowed jugular vein, this trial may help determine if surgery could help.
Beijing, Beijing MunicipalityAges 18–75 - NCT07563322Recruiting
Nicotinamide Riboside for Combined Pulmonary Hypertension
This study tests whether nicotinamide riboside (a B-vitamin supplement) can help people with combined pulmonary hypertension—a condition where blood pressure in the lungs is too high. The researchers want to understand how this supplement affects the body's energy metabolism and whether it might reduce symptoms and improve heart function.
Nashville, TennesseeAges 18–85 - NCT07560436RecruitingPhase 2
Stents for Heart Failure With Normal Pumping
This trial tests whether placing stents in coronary arteries helps patients with heart failure who still have a strong-pumping heart. The study aims to see if improving blood flow to the heart reduces symptoms and improves quality of life.
LondonAges 18 years+ - NCT07566091Recruiting
Stent Comparison Study With Vitamin C for Heart Disease
This trial compares two drug-coated stents for treating blocked heart arteries, with or without vitamin C (ascorbic acid). It tests whether sirolimus plus vitamin C is as safe and effective as everolimus. If you need a stent, this study may help determine which medication coating works best for you.
SeoulAges 19 years+ - NCT07564219Recruiting
Beta-Hydroxybutyrate to Boost CAR-T Cell Therapy in Multiple Myeloma
This trial tests whether a natural metabolite called beta-hydroxybutyrate can strengthen CAR-T cell therapy (a type of cancer-fighting cell treatment) in multiple myeloma patients. The goal is to help your immune cells work better against your cancer.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT07560982Recruiting
Improving medication adherence in advanced heart failure
This study looks at whether patients with severe heart failure follow their prescribed medications as recommended by treatment guidelines. The researchers want to understand what helps or prevents patients from taking their medicines correctly, which could improve their heart function and symptoms.
BergamoAges 18–75 - NCT07561320RecruitingPhase 4
Two ways to treat enlarged veins in your leg
This study compares two minimally invasive procedures to treat enlarged great saphenous veins (a vein in your thigh that can cause swelling, pain, or skin changes). Both procedures seal off the problematic vein by either using heat and mechanical motion or injecting a foaming substance.
São Paulo, São PauloAges 18 years+ - NCT07567625Recruiting
Heart Attack Treatment Without a Stent
This trial tests whether patients who have had a heart attack with a specific type of artery blockage can be safely treated without placing a metal stent (tube) in their artery. Doctors will monitor whether the blockage stays open on its own.
Harbin, HeilongjiangAges 18–75 - NCT07566598Recruiting
Brain Blood Flow Measurement After Stroke Treatment
This study measures how well blood flows through the brain after a special procedure to remove a blood clot causing stroke. Researchers use a tiny temperature sensor to understand blood circulation, which may help improve stroke care.
Nice, Alpes-maritimesAges 18–80 - NCT07560306RecruitingPhase 3
New Heart Scan to Detect Blood Clots in Amyloid Heart Disease
This study tests a new type of imaging scan ([64Cu]FBP8 PET) to detect blood clots that may form in the heart's left atrial appendage (a small pouch in the heart) in patients with amyloid cardiomyopathy (a disease where abnormal protein builds up in heart muscle) who also have irregular heartbeat. The scan may help doctors catch clots earlier and prevent strokes.
Boston, MassachusettsAges 18 years+ - NCT07564778Recruiting
Pain Management After Cardiac Arrest Recovery
This study examines how to better treat pain in patients who have survived cardiac arrest and are unconscious in the hospital. Researchers want to understand pain experiences and test pain-relief strategies during early recovery.
HalmstadAges 18 years+ - NCT07560592Recruiting
Salt Intake Study for Recently Hospitalized Heart Failure
This study looks at how salt intake affects people who were just admitted to the hospital with heart failure. Researchers want to understand if managing salt differently can help your heart work better and prevent future hospitalizations.
New Brunswick, New JerseyAges 18 years+ - NCT07564882Recruiting
Music and Mobile Apps to Help Babies With Heart Surgery Pain
This study tests whether music and a mobile app can help reduce pain and stress in babies aged 2–12 months who have had heart surgery. Researchers will measure pain levels and vital signs like heart rate and breathing.
AnkaraAges 2 months–1 year - NCT07563842Enrolling by invitation
Defining Abdominal Pressure Complications After Surgery
This study is updating medical definitions for a serious condition called abdominal compartment syndrome—where pressure builds up in the belly after surgery or critical illness. The research involves expert doctors and patients who have experienced this condition, working together to clarify what it is and how to recognize it.
LublinAges 18 years+ - NCT07563387Enrolling by invitation
Ear Stimulation to Help Speech Recovery After Stroke or Brain Injury
This study tests whether a gentle electrical stimulation applied to a nerve in the ear can help improve speech and language abilities in people who have had trouble speaking since a stroke or traumatic brain injury. The goal is to see if this non-invasive treatment can help rewire the brain to recover language skills.
Jacksonville, FloridaAges 18–80 - NCT07563608Recruiting
Understanding High Blood Pressure in the Lungs for Dialysis Patients
This study investigates why some dialysis patients develop high blood pressure in their lung blood vessels and how it affects their health. Researchers will assess heart function and follow patients over time to better understand this condition.
Pavia, LombardyAges 18–75 - NCT07563452Recruiting
How Exercise Affects Muscles in People Taking Cholesterol Medicine
This study compares how muscles recover after exercise in people who take statin medications (cholesterol-lowering drugs) versus those who don't. Researchers want to understand if statins affect how well muscles bounce back from physical activity.
Innsbruck, TyrolAges 30–65 - NCT07561034Recruiting
Home Exercise Program for Pulmonary Hypertension and Lung Disease
This study tests whether daily home exercises can help people with pulmonary hypertension (high blood pressure in the lungs) combined with interstitial lung disease (scarring of lung tissue). Researchers will send you daily messages to support your exercise routine and see if it improves your symptoms and quality of life.
Rochester, New YorkAges 18 years+ - NCT07563998Recruiting
Fast heart attack blood test in the ambulance
This study tests whether a quick blood test done by paramedics in the ambulance can safely rule out a heart attack in patients with chest pain or similar symptoms. The goal is to help patients get faster, more accurate care before reaching the hospital.
Aarhus NAges 18 years+ - NCT07562178Recruiting
Pemafibrate to prevent stroke from brain artery narrowing
This trial tests whether a medication called pemafibrate can help prevent future strokes in people who have had a recent stroke or TIA (mini-stroke) caused by a narrowed artery inside the brain. The medication works by lowering triglycerides (a type of fat in the blood).
Toyoake, Aichi-kenAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.