Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,982 recruiting studies in this area right now.
By phase
- Not applicable7,962
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke844
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California465
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas118
Recruiting studies9,979 total
- NCT02972008Recruiting
Looking for blood markers that predict complications after TAVI
This study enrolls older adults having a minimally invasive heart valve procedure (TAVI) to find “epigenetic” risk markers—signals in the body that may predict who is more likely to have complications during the procedure. If you qualify, your blood and/or samples may be studied to improve safety for future patients.
LilleAges 70 years+ - NCT02972385Recruiting
Testing how genes affect warfarin dosing in Hispanic and Latino adults
This study looks at how a person’s genes may affect how they respond to warfarin, a blood-thinner, so dosing can be safer and more accurate. It specifically focuses on Hispanic and Latino adults.
Tucson, ArizonaAges 18 years+ - NCT02973633RecruitingEarly Phase 1
Heart failure MRI brain-wave images after heart trouble
This early-phase study uses a special MRI scan to look at the heart in people with heart failure (and related heart changes). It aims to see whether these MRI results can better characterize heart disease and help doctors understand what’s going on.
Charlestown, MassachusettsAges 18–85 - NCT02979951Recruiting
IV fosfomycin for serious bacterial infections
This trial studies whether IV (through a vein) fosfomycin can treat severe bacterial infections in adults. It may help people whose infection is covered by the standard fosfomycin use and who need hospital-level care.
Hall in TirolAges 18 years+ - NCT02988128Recruiting
Medical device registry for Medtronic neurovascular products
This study follows people who receive a specific Medtronic neurovascular device to learn about safety and performance over time. It may help improve how these devices are used and monitored in real-world care.
Buenos AiresAges 18 years+ - NCT02996552Recruiting
Ring repair for mild-to-moderate leaky right valve
This trial looks at whether adding a specific repair to the right valve (called tricuspid annuloplasty) during mitral valve surgery helps people whose right valve leakage is not severe. It compares doing the extra right-valve repair versus doing only the mitral valve repair.
Rozzano, MilanoAges 18 years+ - NCT02997254Recruiting
Testing computer methods that analyze atrial fibrillation heart signals
This study compares different computer “analysis methods” that look at real-time heart recordings from people with atrial fibrillation. It may help improve how atrial fibrillation is evaluated during/after an ablation procedure.
Stanford, CaliforniaAges 21–90 - NCT02998788Recruiting
Heart failure risk monitoring for hospitalized adults
This trial studies how to better assess and manage risk in people hospitalized with heart failure or related serious heart problems. It may help by improving how clinicians monitor your condition over time and decide next steps.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT03001180Recruiting
Study blood and tissue markers in vascular anomalies
This study collects extra blood (and sometimes tissue during procedures) to look for markers that can help doctors better understand vascular anomalies. It may not be a treatment, but it can improve future care by finding patterns linked to the condition.
Boston, MassachusettsAges 1 day+ - NCT03003299Recruiting
Valve replacement for failing aortic bioprosthetic valves
This trial studies a new “valve-in-valve” procedure to treat a failing aortic bioprosthetic valve. It may help people improve blood flow through the heart valve and reduce valve-related problems.
Phoenix, ArizonaAges Any age - NCT03016806Recruiting
Umbilical cord blood transplant from unrelated donors
This trial studies transplanting healthy blood-forming cells from an umbilical cord blood donor who is not related to you. It may help people with certain blood cancers, immune disorders, or other serious diseases when a standard transplant plan is needed.
Rochester, New YorkAges 2 months–75 years - NCT03017820RecruitingPhase 1
Vaccine plus immune drugs for relapsed blood cancers
This early-phase trial tests a personalized-style vaccine (called VSV-hIFNβ-NIS) given alone or with other cancer-fighting medicines, including drugs that help the immune system attack. It is designed for people with certain relapsed or hard-to-treat multiple myeloma, acute myeloid leukemia, or lymphomas, to see if the treatment can shrink tumors and improve outcomes.
Scottsdale, ArizonaAges 18 years+ - NCT03022552Recruiting
Heart attack research add-on study on blood clotting platelets
This study looks at blood clotting (platelets) during the first phase after a heart attack. You may be able to join if you were recently diagnosed with a heart attack and received standard heart-attack blood thinners like aspirin and a second anti-platelet medicine.
New York, New YorkAges 21–99 - NCT03035747Recruiting
Registry for treatment of varicose veins
This study collects information about people who have varicose veins with abnormal backflow in the leg veins. It’s meant to track how treatments for chronic venous problems are working over time, which can help improve care for others in the future.
Saint PetersburgAges 18 years+ - NCT03042988Recruiting
Heat stress test in people with low nerve control and high blood pressure
This study checks how your body’s blood pressure and stress responses change after being exposed to heat overnight. It’s meant for people with autonomic failure (like certain Parkinson-related or nerve-function conditions) who also have high blood pressure while lying down, which may help researchers understand safer ways to manage it.
Nashville, TennesseeAges 18–80 - NCT03047369Recruiting
Myelin brain disorder research biobank for samples and data
This study collects brain-related medical information and biological samples to help researchers better understand leukodystrophies and other white-matter brain disorders. It may help future diagnosis and treatments by building a valuable “biobank” of patient data and samples.
Los Angeles, CaliforniaAges Any age - NCT03050268Recruiting
Study of childhood cancer risk in families
This study looks at inherited (family) risk for childhood cancers, including families with early cancers or known cancer risk conditions. It may help researchers understand why some children get cancer and improve future risk detection and care.
Memphis, TennesseeAges Any age - NCT03049254Recruiting
Registry and blood/tissue study for certain sudden heart death causes
This study builds a registry and collection of samples to better understand families affected by sudden heart death and related heart rhythm problems that are not clearly caused by a heart attack. It may help researchers identify patterns and improve future care, and it offers a way for patients and families to contribute to research.
Rochester, MinnesotaAges Any age - NCT03091452Recruiting
Atrial fibrillation surgery registry for people treated with ablation
This study is a real-world registry that collects health information from people who have atrial fibrillation and were treated with a heart surgery procedure called ablation. It may help doctors better understand outcomes and care for people with this condition.
München, BavariaAges 18–100 - NCT03103932Recruiting
Blood test–guided discharge for people hospitalized with heart failure
This trial checks whether using a blood test (a “biomarker”) can help doctors decide when it’s safe to send people home after a hospital stay for worsening heart failure. It may help reduce avoidable readmissions while keeping you safe.
Ottawa, OntarioAges 18 years+ - NCT03110822RecruitingPhase 1
Ruxolitinib, steroids, and lenalidomide for hard-to-treat myeloma
This Phase 1 trial tests a combination of ruxolitinib plus steroids and lenalidomide in people with relapsed or refractory multiple myeloma. It’s designed for patients who have had at least two prior treatment options and whose myeloma is getting worse or not responding.
Alhambra, CaliforniaAges 18 years+ - NCT03109197Recruiting
SUDC registry to study sudden unexplained child deaths
This registry collects information (and sometimes DNA) from families affected by sudden unexplained death, to help researchers learn possible underlying causes. If you qualify, you may be contacted about participating in a DNA study or completing family information.
New York, New YorkAges 11 months–100 years - NCT03113552Recruiting
How mitral valve bulging location affects long-term repair outcomes
This study looks back at people who had mitral valve repair surgery to see whether the exact location of a valve problem predicts long-term results. It may help doctors better predict outcomes after surgery and plan follow-up care.
Amiens, PicardieAges 18 years+ - NCT03127761Recruiting
Transplant study for Medicare patients with advanced myeloma
This study looks at outcomes of an allogeneic transplant (a donor-based transplant) in people with stage II–III multiple myeloma or primary plasma cell leukemia who have Medicare. It may help doctors better understand which patients benefit and what to expect before and after transplant.
Minneapolis, MinnesotaAges Any age
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,982 recruiting cardiology studies from the U.S. registry right now, out of 15,268 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.