Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,576 recruiting studies in this area right now.
By phase
- Not applicable2,951
- Phase 4240
- Phase 2131
- Phase 3102
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University60
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University21
Where studies are running
- California152
- New York79
- Massachusetts65
- Florida64
- Texas50
- North Carolina41
- Illinois40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,576 total
- NCT06097091Recruiting
Pain education for fibromyalgia patients
This trial tests if learning about how your brain and nerves process pain can help reduce fibromyalgia symptoms. You will attend sessions that teach you about the science of pain and how to manage it better.
TaipeiAges 18–64 - NCT06453109Recruiting
Focused ultrasound for chronic back pain with opioid use
This study tests whether focused ultrasound (a non-invasive treatment using sound waves) can help people with chronic back pain who also have opioid use disorder and anxiety. It aims to find a better way to manage pain without relying on opioids.
Washington D.C., District of ColumbiaAges 18–75 - NCT07628218Recruiting
Video versus in-person exercise training for heel pain
This trial compares two ways to learn exercises for plantar fasciitis (heel pain caused by tissue strain): watching instructional videos on your own versus attending sessions with a doctor or trainer. The goal is to see which method helps reduce pain and improve walking more effectively.
BalıkesirAges 18–70 - NCT06697860Recruiting
Shockwave vs. massage for chronic heel pain
This study compares two treatments for chronic heel pain (plantar fasciitis): radial shockwave therapy and Graston technique (a special scraping massage). It aims to see which works better to reduce pain and improve function in adults aged 20–45 who have had symptoms for more than 3 months.
Lahore, Punjab ProvinceAges 5 months–10 months - NCT07626684Enrolling by invitation
Ice Pack After Minimally Invasive Hysterectomy Surgery
This study tests whether applying ice packs to the abdomen after a minimally invasive hysterectomy (removal of the uterus through the vagina) helps reduce pain and speed recovery. You would be randomly assigned to either receive ice pack treatment or standard care.
MuğlaAges 48–70 - NCT07626632Recruiting
Tyler Twist vs. Eccentric Exercises for Tennis Elbow
This study compares two exercise approaches for treating lateral epicondylitis (tennis elbow) in people aged 20–40. It tests whether a specific twisting exercise called the Tyler Twist works better than eccentric exercises (where you lengthen a muscle under tension) to reduce pain and improve grip strength.
Lahore, Punjab ProvinceAges 20–40 - NCT07628452Recruiting
Aerobic exercise versus relaxation for period pain
This study compares two natural approaches—regular aerobic exercise and progressive muscle relaxation—to help reduce painful periods. You'll be assigned to one approach and tracked to see which works better for mild to moderate period cramping.
Okāra, Punjab ProvinceAges 17–24 - NCT07626489Recruiting
Numbing injection to reduce pain after lung surgery
This trial tests whether injecting a numbing medication (ropivacaine) mixed with a steroid (Diprospan) into the surgical area before chest surgery can reduce pain after the procedure. If it works, patients may need fewer pain pills and feel more comfortable during recovery.
Beijing, Beijing MunicipalityAges 18–64 - NCT07627308Recruiting
Ultrasound vs Fluoroscopy for Nerve Injections in Back Pain
This trial compares two imaging methods—ultrasound and fluoroscopy (X-ray)—to guide nerve injections for leg pain caused by compressed nerves in the lower back. The goal is to see which method is safer and more effective at relieving your pain.
Tanta, Gharbia GovernorateAges 18–75 - NCT07626346Recruiting
Pain relief medication added to shoulder surgery nerve block
This trial tests whether adding a medication called dexmedetomidine to a numbing injection around shoulder nerves can improve pain control after laparoscopic shoulder surgery. The goal is to see if this combination works better than the numbing medication alone.
CairoAges 18–65 - NCT07626463Recruiting
Local anesthetic injection to reduce pain after laparoscopic surgery
This trial tests whether injecting a local anesthetic (numbing medicine) and a steroid around the surgical area before surgery reduces pain after laparoscopic procedures like gallbladder, appendix, or hernia repair. The goal is to help patients recover more comfortably with potentially less pain medication needed.
Beijing, Beijing MunicipalityAges 18–64 - NCT07628387Recruiting
Exercise Types for Restless Legs in Pregnancy
This study compares two types of exercise—aerobic (heart-pumping) and muscle relaxation—to help pregnant women with restless leg syndrome sleep better and feel less tired. Restless leg syndrome causes uncomfortable sensations in the legs, especially at night, which disrupts sleep during pregnancy.
Lahore, Punjab ProvinceAges 20–40 - NCT07629388Recruiting
Nerve block for pain after knee replacement surgery
This trial tests whether adding a nerve block (a numbing injection near the nerve) to the usual pain plan can better control pain after a total knee replacement. The goal is to help you recover with less pain and fewer side effects.
DijonAges 18 years+ - NCT07625007Recruiting
Shortwave Therapy for Diabetic Nerve Pain
This trial tests a shortwave treatment to relieve pain and other nerve symptoms in people with diabetic peripheral neuropathy (nerve damage from diabetes). It is for adults who have not found enough relief from standard nerve medications.
ChongqingAges 18–85 - NCT07627542Recruiting
Smartphone use and neck posture in arthritis patients
This study looks at how much time people with rheumatoid arthritis or ankylosing spondylitis spend on smartphones and how it affects their neck posture, balance, and disability. Understanding this connection may help doctors give better advice about phone use and neck health.
Konya, MeramAges 18–65 - NCT07624136Recruiting
Kinesio Taping for Shoulder Flexibility and Range of Motion
This study tests whether a special athletic tape (Kinesio tape) applied to your lower back and shoulder area can improve flexibility and reduce shoulder pain in people with chronic shoulder impingement syndrome—a condition where shoulder structures get pinched, causing long-term pain and stiffness.
Ankara, AltindagAges 20–40 - NCT07623304Recruiting
Exercise guidance system after spinal fusion surgery
This study tests a computer system that guides exercise recovery after spine surgery. It aims to help you heal better and move more safely at home using your WiFi connection.
Nantong, JiangsuAges 18–65 - NCT07628348Recruiting
Physical therapy for neck pain from disc herniation
This study tests a physical therapy technique called DRT (Diaphragmatic Respiration Training) to help patients with neck pain, tingling in the arm, and limited neck movement caused by a slipped disc in the neck. The goal is to improve neck flexibility, reduce pain, and expand the chest.
Lahore, Punjab ProvinceAges 35–55 - NCT07627854Recruiting
Cold therapy after knee replacement surgery
This study compares two ways to reduce pain and swelling after total knee replacement: a special cold wrap (cryocuff) versus a standard ice pack. You'll help researchers understand which method works better for your recovery.
Kremmen, BrandenburgAges 18 years+ - NCT07629323Enrolling by invitation
Spinal Pain Relief During Hiatal Hernia Surgery
This trial tests whether injecting pain medication directly into the spinal fluid during a minimally invasive stomach surgery (called fundoplication) helps reduce pain after the operation. Fundoplication is used to treat severe acid reflux.
Karlstad, Värmland CountyAges 18 years+ - NCT07629141Recruiting
Muscle Position and Dry Needling for Neck Pain
This study tests whether the position of your neck muscle affects how well dry needling (inserting thin needles into tight muscle knots) relieves chronic neck pain. Dry needling may help reduce pain by relaxing tense muscles.
Alcalá de Henares, MadridAges 18–80 - NCT07621367Recruiting
Gut oxygen therapy for bowel problems from low oxygen
This trial tests a treatment that delivers oxygen directly to the gut through a small tube. It is for people with long-term heart failure or sleep apnea who also have belly pain, bloating, constipation, or diarrhea.
Nanjing, JiangsuAges 18 years+ - NCT07627425Enrolling by invitation
Staples vs. Sutures for Hernia Repair Mesh
This trial compares two methods of attaching mesh during hernia surgery—staples versus sutures—to see which leads to better healing and fewer problems after surgery. You'd have a 50/50 chance of receiving either method.
KarachiAges 18–75 - NCT06696898Recruiting
Stretching with and without muscle release for sciatica
This study tests if adding myofascial release (a type of hands-on therapy for tight muscles) to a standard self-stretching program helps relieve sciatica pain and improve movement. It's for people with long-standing (chronic) one-sided sciatica.
Lahore, Punjab ProvinceAges 25–50
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,576 recruiting pain medicine studies from the U.S. registry right now, out of 6,474 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.